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김신철(Kim Sin-Chul),김광배(Kim Kwang-Bae) 대한건축학회 2011 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.31 No.2(계획계)
The purpose of this study is to comprehensively analyze the works of Morphosis, the US architect, find out his architectural characteristics and redesign the works of Morphosis in Korea after extracting architectural styles from the data. To the end, it is necessary to consider the architectural background in LA where Morphosis worked and LA School theoretically and find out what influence the background had on Morphosis. - omit - Based on the research, architectural characteristics of Shinchon will be added to the architectural styles of Morphosis. It is very interesting to shed new light to the works of Morphosis in Korea and redesign them in a new current perspective through this process.
김신철(Kim Sin-Chul),김광배(Kim Kwang-Bae) 대한건축학회 2010 대한건축학회논문집 Vol.26 No.10
The purpose of the study is to investigate if the influences from three masters, Le Corbusier, Carlo Scarpa, and Louis Kahn, who influenced Mario Botta in his architectural activity and works, are revealed in his architectural style, to define his architectural styles that express his identity the most consistently and universally, and to analyze how the architectural style is materialized via what elements comprehensively. The research will be processed in three steps. First, the architectural philosophy and style inherited from three masters would be investigated from literature. Second, Mario Botta's architectural style would be re-defined from five perspectives, and five built works from three building types, house, public facility and religious building, would be selected and be analyzed from the five perspectives. Third, the outcome would be drawn from the analysis. The results of the study are as follows. First, It was confirmed that Mario Botta‘s architectural style was influenced from three masters as follows; his methodology of floor plan composition at early house projects, formal composition of elevation, and the use of light in space via sky light. Second, his style was virtually and universally realized in his works in frequent manner. Third, the analysis based on five perspectives reveals that the Euclidean geometry was applied in almost every work, and the symmetric style was applied selectively according to the characteristics of the project irrelevant to the time, building type and scale of the project.
급성 허혈성 뇌졸중에 있어서 혈전 용해제 적용 기준의 위반에 따른 예후 및 합병증에 대한 평가
김신철,천일영,김명천,고영관 대한응급의학회 2002 대한응급의학회지 Vol.13 No.3
Purpose: In many other countries, based on research, recombinant tissue plasminogen activator (r-tPA) has been approved for the treatment of acute ischemic strokes. However, in Korea, little research has been done till now, in spite of using r-tPA widely. We sought to assess the feasibility and the efficacy of treatment and to evaluate the prognosis and complications at the violation of using r-tPA. Our study was compared with other previous studies. Methods: A retrospective review is presented of 25 the cases of patients with acute ischemic stroke treated with r-tPA according to the National Institutes of Neurological Disorders and Strokes (NINDS) protocol. We classified the groups by protocol violation (time, blood pressure, and computed tomography). We then analyzed neurologic outcomes by using the National Institutes of Health Strokes Scale (NIHSS) and complications based on whether or not intracerebral hemorrhage (ICH) had occurred. Results: Of the 25 patients (mean age: 57 males: 19), 6 had time violation (onset time>180 min), 4 had blood-pressure violation (systolic BP> 185 mmHg), 5 had CT violation (low density at initial CT). The NIHSS score improved in 64% of all patients after 24 hours. However, improvement was lower in the case of deviation present than it was in the case of deviation absent (time, blood pressure, and CT, respectively, 20%, 50%, and 40%; p-value respectively 0.0274, 0.8350, and 0.4125). ICH occurred in 6 cases, but in cases of deviation present, ICH occurred at a greater frequency. Conclusion: Our safety and feasibility of outcome compared favorably with NINDS and other previous studies. In addition, we confirmed that the presence of protocol deviation was associated a poor outcome.
출혈성 수포와 호흡곤란을 주소로 내원한 발진열 : 1예 보고 A case report
김신철,김명천,고영관 대한응급의학회 2002 대한응급의학회지 Vol.13 No.3
Murine (endemic) typhus is a zoonotic infection caused by Rickettsia typhi (formerly known as Rickettsia mooseri). Rickettsia typhi is an obligate intracellular organism that multiplies within the cytoplasm of mainly endothelial cells. It is transmitted from rats by injection of contaminated flea feces into the skin of the host. The disease manifests itself with the gradual onset of fever, myalgia, and headache appearing 7-14 days after infection. A maculopapular rash is found in some patients (proportions ranging from 20 to 80% in different series). We report a rare case of murine typhus with presentation of hemorrhagic vesicles and dyspnea which was treated at our emergency department, and we give a brief review of the literature.
Cerivastatin과 Gemfibrozil 병합요법 후에 발생한 횡문근 융해증 : 1예보고
김신철,김명천,고영관 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4
Most currently available statins are associated with an increase with risk of myositis, including rhabdomyolysis. Myopathy is believed to be caused by interference in the cytochrome P450 3A4 enzyme system, which results in a marked increase in reductase activity. Cerivastatin, a new synthetic HMG-CoA reductase inhibitor, is a safe, well-tolerated effective drug for the treatment of patients with dyslipidemia. The drug is metabolized by the cytochrome P450 3A4 and cytochrome P450 2C8 hepatic isoenzymes. Because of this dual metabolic pathway, it has been suggested that cerivastatin is less subject to drug-to-drug interactions. We describe a 60-year-old woman with rhabdomyolysis and localized myositis, after she had taken cerivastatin(lipobay, 0.3 mg/day) and gemfibrozil(lopid, 500 mg/day) for 1month.