멧누에 ( Bombyx mandarina ) 난간단백질 유전자의 유전적 분석

성승현(Seung Hyun Sung),김순정(Soon Jeung Kim),염승식(Seung Shic Yum),김종길(Jong Kil Kim),김기세(Ki Sei Kim),김근종(Keun Chong Kim),문준옥(Jun Ok Moon),이병순(Byong Soon Lee),서동상(Dong Sang Suh) 한국유전학회 2001 Genes & Genomics Vol.23 No.4

Two multigene families, high-cysteine A(HcA) and high-cysteine B(HcB), are located within 140 kb region of chorion locus in Bombyx mori. Each family consists of 15 members and one of each members are transcribed in pairs. We report isolation and characterization of HcA and HcB genes of the wild type silkmoth, Bombyx mandarina. In this study, we examined 6 repeating units out of 15 HcA genes and 6 units of 15 HcB genes of B. mori and B. mandarina, respectively, and found that the arrangements and expression units of these are dramatically different. In addition, we found that most of the sequence variations were located within the C-variable region. These results suggest that the likely mechanism of concerted evolution is gene conversion-like event in HcA/HcB gene pairs.

LD₅₀ 산출방법에 있어서 수리 · 통계학적 특성

김세기,김근종,이병무,Kim Se Ki,Kim Keun-Chong,Lee Byung Mu 한국독성학회 2004 Toxicological Research Vol.20 No.4

Lethal dose 50% ($LD_{50}$) has been commonly used as a parameter for the estimation of acute toxicity not only in animal experiment, but also in human study. Several methods to estimate $LD_{50}$ had been introduced, but Spearman-Karber and Berens-Karber method have been widely used due to their relative convenience and accuracy. However, $LD_{50}$ values estimated from the two methods showed inconsistency and variation depending on the characteristics of mortality data. In this study, the two methods were comparatively investigated in terms of accuracy and stability for the estimation of $LD_{50}$.

모바일 게임 이용의도에 영향을 미치는 요인에 관한 연구

김효정(Kim Hyo-Jeung),한창희(Han Chang Hee),서보밀(Suh Bomil),김근종(Kim Keun-Chong) 한국전자거래학회 2005 한국전자거래학회지 Vol.10 No.1

정보기술의 수용에 대한 연구가 활발하게 이루어지고 있음에도 불구하고, 최근에 급격한 성장과 발전을 이루고 있는 모바일 게임의 이용의도에 대한 연구는 미흡한 실정이다. 따라서, 본 연구에서는 모바일 게임 이용 의도에 영향을 미치는 중요 요인에 관한 실증적 연구를 하였다. TAM과 모바일 게임에 관련된 연구를 기초로 하여 시스템적 요인, 개인적 요인, 사회적 요인이라는 3가지 차원에서 서비스 품질, 사회적 영향, 즉시 접속성, 혁신성, 자기효험이라는 5가지의 항목을 외부변수로 제시하였다. 연구모형의 검증을 위하여, 10~30대의 학생과 직장인을 대상으로 설문조사를 실시하여 261부의 설문응답을 통계분석에 이용하였다. 통계검증 결과, 서비스 품질과 즉시 접속성, 혁신성, 자기효험이 지각된 유용성과 지각된 이용 용이성을 통하여 이용의도에 영향을 미치는 것으로 나타났다. 이러한 연구의 결과를 통하여 기업에서 모바일 게임 서비스를 개발하거나 고객을 대상으로 효과적이고 효율적인 마케팅을 하는데 있어 보다 중점을 두어야 할 요인을 제시하고자 한다. Recently, the mobile game industry is explosively extending and advancing. Nevertheless, although research on IT acceptance has been actively performed, the effective studies have not been accomplished in the acceptance of mobile game. This study, therefore, explores the factors affecting customer’s intention to use mobile game. Five external factors (service quality, social influence, instant connectivity, self-innovativeness, and self-efficacy) are proposed to test the several hypotheses. The factors are classified to three dimensions - system, individual, and society. The research model is based on various studies on TAM(Technology Acceptance Model) and mobile service. A survey of mobile game users collected 270 cases, and we used 261 cases for statistical analyses. The analyses show that service quality, instant connectivity, self-innovativeness, and self-efficacy have an indirect effect on the intention to use through perceived usefulness and perceived ease of use. We provide the important factors that should be focused on when an enterprise develops and promotes new mobile game products.

LD_(50) 산출방법에 있어서 수리·통계학적 특성

김세기(Se Ki Kim),김근종(Keun-Chong Kim),이병무(Byung Mu Lee) 한국독성학회 2004 Toxicological Research Vol.20 No.4

Lethal dose 50% (LD_(50)) has been commonly used as a parameter for the estimation of acute toxicity not only in animal experiment, but also in human study. Several methods to estimate LD_(50) had been introduced, but Spearman-Karber and Berens-Karber method have been widely used due to their relative convenience and accuracy. However, LD_(50) values estimated from the two methods showed inconsistency and variation depending on the characteristics of mortality data. In this study, the two methods were comparatively investigated in terms of accuracy and stability for the estimation of LD_(50).

새로운 p-median 모델을 이용한 셀 생산시스템 디자인

원유경(You-Kyung Won),김근종(Keun-Chong Kim) 한국생산관리학회 2004 한국생산관리학회지 Vol.14 No.3

This paper proposes new p-median mathematical formulations for solving the cell formation (CF) problem in group technology manufacturing. In spite of its successful applications to CF problems that have ever been reported in literature, existing p-median formulations have critical limitations for at least three reasons. First, since CF problem is NP-complete, it takes enormous amount of computation time to solve the problem optimally. Second, existing p-median formulations can solve small to medium-sized CF problems since they require too many binary variables. Some of modified p-median formulations require extra continuous variables and constraints at the cost of decreased binary variables. Third, existing p-median formulations suggest no efficient schemes for implementation of the formulations. These limitations discourage cell designer to apply existing p-median formulations to large-size CF problems. Our modified p-median formulations have fundamental advantages over existing p-median formulations in the sense that they can be applied to large-size CF problems within short computer runtime. Unlike existing p-median formulations which do not utilize any information of the median machines throughout the implementation procedure, our modified p-median formulations introduce the candidate set of median machines so that the models can utilize the information of the median machines from the beginning of implementation procedure. This leads to much speedier implementation of model. Furthermore, we develop an alternative p-median formulation which requires less number of binary variables. Our p-median formulations need no extra continuous variables and constraints. Computational results with medium- to large-size data sets available in literature compare our p-median formulations favorably. 본 논문에서는 그룹테크놀러지 생산시스템에서 기계 셀 형성문제를 푸는 새로운 p-median 모델을 제시한다. 기계 셀 형성문제를 푸는 방법론으로서 p-median 모델은 성과가 좋다는 것이 알려져 있지만 기존의 p-median 모델은 적어도 세 가지 점에서 한계가 있다. 첫째, 셀 형성 문제는 NP-complete이므로 문제를 푸는데 계산시간이 매우 많이 소요된다. 둘째, 기존의 p-median 모델은 이진변수가 많이 필요하므로 중규모 이하의 셀 형성문제에만 적용가능하다. 셋째, 기존의 p-median 모델은 컴퓨터에서 모델을 빨리 실행할 수 있는 별도의 수단이 없다. 이로 인해 기존의 p-median 모델을 대규모 셀 형성문제에 적용하는 데는 한계가 있다. 본 논문에서 제시하는 p-median 모델은 빠른 계산시간 내에 대규모 셀 형성문제를 풀 수 있다는 점에서 기존의 p-median 모델보다 효과적이다. 모델을 실행하는 동안 메디안으로 선정되는 기계에 대한 선택정보를 전혀 활용하지 않는 기존의 p-median 모델과는 달리, 본 논문에서 제시하는 p-median 모델에서는 메디안후보 기계집합을 도입하여 실행 초기부터 메디안으로 선정되는 기계에 대한 선택정보를 활용한다. 더 나아가서 이진변수가 줄어든 p-median 모델을 제시한다. 이 모델은 연속변수나 제약식을 추가로 필요로 하지 않는다. 문헌에서 이용 가능한 큰 사이즈의 데이터들을 가지고 기존의 p-median 모델과 비교계산해 본 결과 본 논문에서 제시한 p-median 모델의 성과가 좋음을 발견하였다.

二母數 옵션 價格 變動性 實證 分析

金槿鐘 홍익대학교 산업기술연구소 1997 産業技術 Vol.7 No.-

There have been many empirical reports that market option prices and theoretical ones have discrepancies. Except the constant elasticity of variance model of Cox, all theoretical models used a one-parameter diffusion coefficient. A two-parameter function has been adopted to see whether we can have a better theoretical model. A regular and a weighted nonlinear least squares methods have been developed. And a numerical method with a finite difference technique is used. The exercise price biases can be reduced substantially.

Single-period Inventory Models with Only One-level Substitution

Kim, Keun-Chong 홍익대학교 산업기술연구소 2002 産業技術 Vol.12 No.-

이 논문은 수요가 시간에 따라 변하고 수입과 비용은 비례적이고 대체 가능하고 임의의 재고 수준의 경우에 한 기간 여러 제품의 최적 재고에 관한 연구이다. 모두 N개의 제품 또는 수요가 존재하는 경우로 상정하였다. 제품 대체는 제품 i가 없어 제품 i-1 또는 제품 i+1을 대신 제공하는 경우에 발생한다. 여기서는 2단계 이윤 극대화 모형이 연구되었고, 탐욕법에 의한 제품대체가 최적임을 알 수 있었다. 또 평균 기대이윤과 그 미분값들을 수식으로 나타낼 수 있었다. 그리고 이윤함수의 성질과 최적해의 여러 가지 흥미있는 성질들도 도출하였다.

노랑초파리 한국 자연집단 내의 체중에 관한 유전 분산 분석

김용성,박영민,서동상,성승현,심미정,성기창,김근종 한국유전학회 1998 Genes & Genomics Vol.20 No.3

We estimated genetic variance components for body weight in D. melanogaster. The second chromosomes of 98 lines were extracted from a Korean natural population. Analyses of heritability and genetic variance were performed by partial diallelic crosses. The correlation coefficient (r) of body weight between females and males was estimated to be 0.2817, which was highly significant at the 0.1% significance level. The heritability (H²) was estimated to be 0.317 for females and 0.308 for males ; the additive genetic variance (σ²A) 0.00136±0.00096 and 0.00127±0.00047; the dominance variance (σ²D) -0.00014±0.00031 and -0.00052±0.00026, respectively. These data indicate that, in this population, mutation-selection balance might be an explanation for the mechanism for the maintenance of genetic variability of body weight.

二母數 先物옵션 價格 變動性 實證 分析

金槿鍾 홍익대학교 산업기술연구소 1998 産業技術 Vol.8 No.-

There have been many empirical reports that market option prices and theoretical one have discrepancies. Except the constant elasticity of variance model of Cox, all theoretical model used a one-parameter diffusion coefficient. A two-parameter function has been adopted to see whether we can have a better theoretical model. A regular and a weighted nonlinear least squares methods have been developed. And a numerical method with a finite difference technique is used. The exercise price biases can be reduced substantially. And to our surprise, parameters of the gold futures options are relatively stable than that of equity options.

우선적 수요 계층이 여럿인 경우의 재고 정책 연구

金槿種 弘益大學校 東北亞企業經營硏究所 2005 企業經營硏究 Vol.2 No.-

Sobel and Zhang worked for inventory policies for systems with stochastic and deterministic demand. They proved that if there is stock in the system, a modified (s,S) policy is optimal with a setup cost to meet the stochastic demand. If there is a smoothing cost instead of the setup cost, the problem corresponds to a standard model with one source of demand. On the other hand, Cohen et al. studied the service constrained (s,S) inventory systems with priority demand classes and lost sales. They treated excess demands as lost sales with a deterministic lead time. They derived an approximate, renewal-based model with Markov-chain. They also develop a greedy heuristic which minimizes expected costs subject to a fill-rate service constraints. We extend the latter results to a general priority model using the idea of the former work, We can get an approximate (s,S) priority demand system and evaluate an effective heuristic for a general priority optimization.