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텐저블 인터페이스를 이용한 건강관리 시스템 설계 및 구현
김규종(Kim Kyu-Jong),신기보(Shin Ki-Bo),이병주(Lee Byung-Joo),최경섭(Choi Kyung-Sub),최영미(Choi Young-Mee),주문원(Choo Moon-Won) 한국콘텐츠학회 2005 한국콘텐츠학회 종합학술대회 논문집 Vol.3 No.2
본 연구에서는 사용자의 제어를 인식하는 텐저블 머신을 제작하기 위하여 게임 형식의 콘텐츠를 제어할 수 있는 기술을 제시한다. 특히 설문조사를 통해 헬스기기에 반영할 사용자 콘텐츠 선호도를 분석하여, 게임인공지능과 게임물리 기술을 활용한 체감형 게임 개발로 현실성을 극대화시킨 건강관리 시스템을 설계하고 구현하였다. In this paper, we designed and made a bicycle with tangible interface using a game to make a tangible interface for health-care system In particular, through a survey of the preference of users, we have showed a tangible machine which is possible to recognize users' control as a form of tangible interface, have presented the controllable method of a game contents, have provided the contents reality maximized using game AI and game physics.
궤양성 대장염에서 대장암의 조기진단을 위한 Telomerase 및 hTERT의 임상적 유용성울산대학교 의과대학 서울아산병원 소화기내과
김규종 ( Kyu Jong Kim ),명승재 ( Seung Jae Myung ),홍성수 ( Seong Soo Hong ),이선미 ( Sun Mi Lee ),변정식 ( Jeong Sik Byeon ),양석균 ( Suk Kyun Yang ),홍원선 ( Weon Seon Hong ),김진호 ( Jin Ho Kim ),민영일 ( Young Il Min ) 대한장연구학회 2004 Intestinal Research Vol.2 No.1
Clinical Usefulness of Telomerase and hTERT for the Detection of Colon Cancer in Ulcerative Colitis Background/Aims: Telomerase and telomerase reverse transcriptase (hTERT), are specifically expressed in cancer cells, making them candidate markers for the early detection of cancer. The aims of our study were to determine whether these assays may be useful in the diagnosis of colorectal cancer (CRC) developed in ulcerative colitis (UC) patients. Methods: Luminal washings and biopsies were collected during colonoscopy in 66 patients; 34 with CRC, 21 with UC, and 11 controls. Telomerase activity was detected by telomeric repeat amplification protocol (TRAP) and hTERT was assayed by RT-PCR Results: Telomerase activity was detected in biopsies from 33/34 (97%) CRC, 14/21 (67%) UC, and 3/11 (27%) controls. hTERT was positive in biopsies from 32/34 (94%) CRC, 12/21 (57%) UC, and 5/11 (45%) controls. In washing fluid, 21/34 (62%) of CRC patients were positive for telomerase, but UC patients and controls were negative. The sensitivity of telomerase for CRC was 97% in tissues and 62% in washing fluid. The specificity of telomerase in washing fluid was 100%, whereas the specificity of telomerase or hTERT mRNA in tissues was 47% each. Conclusions: The low specificity of telomerase and hTERT in colonic tissue suggest that these are not candidate markers for CRC arising in UC. Telomerase in colonoscopic luminal washings, however, may be a novel marker for early CRC in UC. (Intestinal Research 2004;2:15-20)
송성은 ( Sung Eun Song ),박무인 ( Moo In Park ),문원 ( Won Moon ),박선자 ( Seun Ja Park ),김규종 ( Kyu Jong Kim ),김재현 ( Jae Hyun Kim ),김경미 ( Gyung Mi Kim ),김종국 ( Jong Kuk Kim ),심영주 ( Young Joo Sim ),이정민 ( Jung Min 대한소화기기능성질환·운동학회 2009 Journal of Neurogastroenterology and Motility (JNM Vol.15 No.1
Dermatomyositis is a rare autoimmune disorder afflicting an estimated 6-10 million people worldwide that has a distinct clinical entity identified by a characteristic skin rash and inflammatory myopathy. It can be combined with other connective tissue diseases such as systemic sclerosis or systemic lupus erythematosus. In addition to primary disturbances of limb muscle and skin, extramuscular manifestations include dysphagia, cardiac conduction abnormalities, interstitial lung disease or subcutaneous calcifications. Dysphagia occurs in 12%-54% of those with dermatomyositis, manifests gradually over weeks to months rather than in acutely, and is diagnosed with high-resolution esophageal manometry and video-fluoroscopic monitoring during swallowing. We report a case of dermatomyositis presenting initially with acute oropharyngeal dysphagia and review the available swallowing studies and related literature. (Kor J Neurogastroenterol Motil 2009;15:65-69)
서정아 ( Jeong Ah Seo ),김규종 ( Kyu Jong Kim ),신은경 ( Eun Kyung Shin ),이은미 ( Eun Mi Lee ),문원 ( Won Moon ),박무인 ( Moo In Park ),김영옥 ( Young Ok Kim ),박선자 ( Seun Ja Park ) 대한소화기학회 2007 대한소화기학회지 Vol.49 No.3
Cowden`s disease, also known as various hamartomatous malformations of multiple organs, is a rare autosomal dominant disorder. The most important feature of Cowden`s disease is its frequent association with malignant neoplasm, particularly in the breast and thyroid gland. Cowden`s disease with malignant neoplasms, is quite rare in Korea so far. We report a case of Cowden`s disease associated with breast cancer in a 41-year-old female who underwent routine health cheek-up. (Korean J Gastroenterol 2007;49:183-186)
위 점막 병변의 겸자 생검과 점막절제술 후의 조직 진단의 비교
김지연 ( Jee Yeon Kim ),이시원 ( See Won Lee ),박이천 ( Lee Chun Park ),신중광 ( Jung Kwang Shin ),박남영 ( Nam Young Park ),문원 ( Won Moon ),김규종 ( Kyu Jong Kim ),박무인 ( Moo In Park ),박선자 ( Seun Ja Park ),장희경 ( Hee Ky 대한내과학회 2006 대한내과학회지 Vol.71 No.6
목적: 위 선종의 정확한 조직학적 진단은 중요한데 이것은 전암성 병변과 국소적 위암과 연관되어 있다는 보고가 있기 때문이다. 그러나 위 선종의 경우 내시경 생검과 점막 절제술로 절제된 조직과의 진단이 일치하지 않는 경우가 관찰된다. 이에 위 선종 및 조기위암으로 의심되는 병변에 대한 내시경 생검과 점막절제술 후의 조직소견의 차이를 내시경 소견에 따라 분석하여 보고자 하였다. 방법: 2002년 5월부터 2004년 8월까지 고신 대학교 복음병원에서 상부 워장관 내시경상 위 선종 또는 조기위암으로 의심되는 병변이 관찰되어 내시경 점막절제술을 시행한 88명의 환자를 대상으로 후향적으로 절제 전 내시경 생검과의 조직소견을 판정하였다. 결과: 내시경 생겁 결과와 점막 절제술 후 조직소견이 일치한 경우가 52예(59.1%)였다. 내시경 생검에서 위염 또는 선종인 71예 중에서 점막절제술 후 선암으로 판명되었던 경우가 13예 있었다. 이렇게 조직 소견이 선암으로 상향 진단된 경우의 내시경 소견은 발적, 함몰형 병변인 경우에서 빈도가 높았다. 결론: 선종이 의심되는 위점막 병연이 관찰된 경우 내시경 생검이 전체 병변의 조직을 반영하기는 어려우므로 특히 발적이 동반되거나, 함몰형 병변인 경우에는 점막절제술 등의 전체 병변 절제를 통한 조직검사를 반드시 시행하는 것이 진단과 치료에 도움이 될 것으로 생각한다. Background: The correct histological diagnosis of a gastric adenoma is important, because an adenoma has been reported to be a precancerous lesion and is associated with focal gastric carcinoma. However, there is some discrepancy between the histology of a forceps biopsy and that of the endoscopic mucosal resection. This study compared the histological findings of a gastric mucosal lesion in the specimens of a forceps biopsy and an endoscopic mucosal resection. Methods: 88 cases of gastric mucosal lesions, which had been removed by the endoscopic mucosal resection, were reviewed retrospectively. All the patients had undergone a forceps biopsy before the endoscopic mucosal resection. The histological findings of the specimens by a forceps biopsy were compared with those by resection. Results: The histological findings were accordant at 52 of the 88 cases (59.1%). Among the 71 cases with adenoma or gastritis in the biopsied specimens. 13 cases (18.3%) were finally diagnosed with gastric cancer in the resected specimens. Among all the gastritis and adenomas determined by the forceps biopsy, the high-risk groups for adenocarcinomas were characterized by the following endoscopic findings: red-colored and depressed lesions. Conclusions: Biopsy specimens may not be representative of the entire lesion. Therefore, an endoscopic resection of a gastric mucosal lesion is needed for making an accurate histological diagnosis and treatment if adenomas such as red-colored or depressed lesions are suspected. (Korean J Med 71:600-608, 2006)
증례 : 소화기 ; 식도와 위기능 장애가 동반된 만성 가성 장폐쇄증 1예
김부경 ( Bu Kyung Kim ),박무인 ( Moo In Park ),박선자 ( Seun Ja Park ),김규종 ( Kyu Jong Kim ),문원 ( Won Moon ),탁희상 ( Hee Sang Tag ),김성빈 ( Sung Bin Kim ) 대한내과학회 2011 대한내과학회지 Vol.81 No.2
반복적인 복통과 구토를 주소로 내원하여 임상증상과 병력, 고해상도 식도내압검사와 위배출 시간 검사를 통하여 식도와 위기능 장애가 동반된 소장의 만성 특발성 가성 장폐쇄증으로 진단되었고, 보존적 치료로 호전된 비교적 경한 증상의 증례이다. Chronic intestinal pseudo-obstruction (CIPO) is a rare digestive syndrome characterized by symptoms and signs of intestinal obstruction in the absence of mechanical obstruction. A 48-year-old female presented at our facility with severe abdominal pain and vomiting. Simple abdominal radiography revealed small bowel gas and ileus. Computed tomography also revealed a dilated small bowel, but there was no evidence of mechanical obstruction. Esophageal function was decreased based on high-resolution manometry and the gastric emptying time was prolonged on a gastric emptying scan. The patient recovered with conservative treatment. We report a case of chronic intestinal pseudo-obstruction with esophageal and gastric dysfunction. (Korean J Med 2011;81:223-228)
HRSG의 start-up/shutdown curve에 따른 시스템 동특성 해석
차훈(Cha Hoon),김규종(Kim Kyu Jong),송유석(Song Yoo Seok),김정래(Kim Jung Rae) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11
HRSG(Heat Recovery Steam Generator) is one of the main components of CCPP(Combined Cycle Power Plant) and should be operated by appropriate procedure in case of start-up or shutdown. If an abnormal operation of HRSG occurs, the problem including fatigue failure can arises. Therefore, the performance of HRSG by dynamic analysis should be investigated. In this study, dynamic analysis for the HRSG system was carried out by commercial software, ProTRAX. The main variable for the analysis was the change of temperature and mass flow rate from gas turbine according to start-up(cold/warm/hot) and shutdown curve to dynamic analysis. The results showed that the exhaust gas condition of gas turbine was a main factor for performance of HRSG such as flow rate and temperature of main steam from final superheater.