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- 저자 : 김경은 ( Gyung Eun Kim ) (검색결과 5 건)
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Lidocaine에 의한 아나필락시스 및 특이 immunoglobulin E 측정
여진엽 ( Jin Yeop Yeo ),김경은 ( Gyung Eun Kim ),한주영 ( Ju Young Han ),임재형 ( Jae Hyoung Im ),박성욱 ( Sung Wook Park ),김철우 ( Cheol Woo Kim ) 대한천식알레르기학회 2013 Allergy Asthma & Respiratory Disease Vol.1 No.1
Although local anesthetics can cause adverse drug reactions (ADRs), most ADRs to local anesthetics are from vasovagal, toxic, or anxiety reactions, while immunoglobulin E (IgE)-mediated anaphylaxis is extremely rare. We report a case of IgE-mediated anaphylactic reaction to lidocaine. A 27-year-old male patient who had two episodes of anaphylactic reactions after local injection of lidocaine was referred to our clinic for the safe use of local anesthetics for the subsequent dental procedure. Skin prick and intradermal tests were performed with amide local anesthetics; lidocaine, bupivacaine, mepivacaine, and ropivacaine. Lidocaine and mepivacaine showed positive response in prick test, and lidocaine, mepivacaine, and bupivacaine showed positive reactions in intradermal test. Only ropivacaine showed negative response both in prick and in intradermal test, and the patient was successfully treated with it. To detect serum-specific IgE, we prepared lidocaine-human serum albumin (HSA) conjugate. Enzyme-linked immunosorbent assay result showed high level of specific IgE to lidocaine-HSA conjugate in serum of the patient. This case suggests that local anesthetics can elicit specific IgE-mediated allergic reactions, and both skin prick and intradermal test should be performed in case of suspected IgE-mediated allergic response to local anesthetics. (Allergy Asthma Respir Dis 1(1):98-101, 2013)
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정용진(Yong-Jin Jeong),김주남(Ju-Nam Kim),서지형(Ji-Hyung Seo),김경은(Gyung-Eun Kim) 한국식품영양과학회 2004 한국식품영양과학회지 Vol.33 No.6
액상칼슘을 첨가한 한방 칼슘제를 중년여성에게 칼슘제 섭취 수준에 따라 3개의 그룹(대조군, Ca500, Ca750)으로 구분하여 일정기간 섭취시키고, 이들의 골밀도 및 골형성 지표의 변화에 대해 조사하였다. 6개월 후 대조군의 골밀도가 감소한 반면, Ca750군의 요추 골밀도는 초기값 0.850에서 0.865로 증가하였다. 또한 혈청 칼슘과 혈청 osteocalcin의 증가 및 요중 deoxypyridinoline의 감소는 액상칼슘 첨가 수준이 높을수록 섭취 전후 차이가 뚜렷하였다. 특히 Ca750군에서는 혈청 osteocalcin 함량이 초기 5.50 ng/mL에서 칼슘제 섭취후 7.93 ng/mL로 유의적인 증가를 나타내었다. 전반적인 연구 결과에서 액상칼슘 섭취에 의한 유의적인 골밀도 증가는 확인되지 않았으나, 칼슘제 섭취에 따른 위장장애나 변비 등의 부작용이 없고 골형성 표지성분의 증가 및 골흡수 표지 성분의 감소를 나타내어, 장기적인 연구가 요망된다. Effects of liquefied calcium supplement on bone mineral density (BMD) and bone health index (osteocalcin, deoxypyridinoline) were investigated in 12 middle aged women. Middle aged women were arranged into 3 groups such as control, Ca500 and Ca750 by liquefied calcium supplement level. BMD was measured at the spine (vertebrae L2-L4). After 6 month, BMD of control group dropped but that of Ca750 were increased from 0.850 to 0.865. The increase in serum calcium and osteocalcin level, and the decrease in urine deoxypyridinoline level were observed in by calcium supplement groups. The bone health index of serum was changed as much as level of calcium supplement. The serum osteocalcin level of Ca750 significantly increased to 7.93 ng/mL after 6 months of calcium supplement. Although we didn't get any significant difference in BMD, we found that the liquefied calcium had no side effect and led effective change in bone health index. Hereafter, we suppose that the liquefied calcium will be available to develop healthy products for preventing osteoporosis.
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최용준 ( Yong Jun Choi ),박진석 ( Jin Seok Park ),김경은 ( Gyung Eun Kim ),한지영 ( Jee Young Han ),나소연 ( So Yun Nah ),방병욱 ( Byoung Wook Bang ) 대한소화기학회 2014 대한소화기학회지 Vol.63 No.5
Colonoscopic examination is a safe procedure, however, unexpected complications can sometimes occur. Bleeding and perforation of the colon have been reported as the most common complications. Hemoperitoneum after colonoscopy is an unusual complication, but it may be catastrophic. We report on a 20-year-old man who experienced left low quadrant pain after undergoing colonoscopy. Hemoperitoneum was diagnosed using abdominal CT. A laparoscopic exploration was urgently performed, revealing a lacerated mesocolon of the descending colon. Bleeding of the injured site was controlled without complication. The patient recovered fully without signs of recurrent bleeding. This report implies that if the patient has persistent abdominal pain after undergoing colonoscopy, we should consider hemoperitoneum as one of the causes. To the best of our knowledge, no case of isolated laceration of the mesocolon of the descending colon after colonoscopy has been reported.
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증례 : 급성 호흡곤란증후군 환자에서 발생한 거대세포바이러스 대장염에 의한 장협착
한주영 ( Ju Young Han ),이홍렬 ( Hong Lyeol Lee ),곽승민 ( Seung Min Kwak ),권계숙 ( Kye Sook Kwon ),김경은 ( Gyung Eun Kim ),김준미 ( Joon Mee Kim ),조재화 ( Jae Hwa Cho ) 대한내과학회 2013 대한내과학회지 Vol.84 No.2
결론적으로 거대세포바이러스 대장염은 면역기능이 유지된 사람에게서는 드문 질환으로 알려져 있으며 그에 따른 합병증으로 대장협착이 발생한 경우는 더욱 흔하지 않다. 연자들은 정상면역을 가진 성인에서 폐렴에 의한 급성 호흡곤란 증후군과 패혈증으로 중환자실 치료 중 지속적인 복부통증, 고열, 혈변으로 대장내시경을 시행하여 거대세포 바이러스 대장염을 진단하였고 이로 인한 장협착이 발생하여 장절제술까지 시행한 1예를 경험하여서 보고하였다. Cytomegalovirus (CMV) infection has been described in immunosuppressed individuals such as patients with AIDS, those receiving chemotherapy, and post-transplantation. CMV can cause severe disease either via reactivation of latent virus or via primary infection. In immunocompetent patients, CMV infection is usually transient and does not exhibit many symptoms. The colon is the site most frequently affected by severe CMV disease in immunocompetent patients. Clinically, CMV colitis commonly presents with diarrhea, fever, and abdominal pain. Although some patients recover spontaneously, others suffer from severe complications, such as bowel perforation, severe gastrointestinal bleeding and, rarely, stricture, and surgery is the choice of treatment in these patients. We report a case of stricture of the proximal transverse colon, presenting as a complication of CMV colitis, in an immunocompetent man with acute respiratory distress syndrome. We performed laparoscopic segmental resection of the proximal transverse colon. (Korean J Med 2013;84:284-289)
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혈액투석 중 저혈당 빈발 말기신부전증 환자에서 인슐린 유사물질 사용 예
송준호 ( Joon Ho Song ),이승우 ( Seoung Woo Lee ),홍성빈 ( Seong Bin Hong ),장지훈 ( Ji Hun Jang ),김경은 ( Gyung Eun Kim ),한주영 ( Ju Young Han ),양동혁 ( Dong Hyuk Yang ) 대한내과학회 2012 대한내과학회지 Vol.83 No.5
Day-to-day insulin requirements often change due to subtle variations in insulin metabolism in patients with type 2 diabetes undergoing hemodialysis. In such cases, intra-hemodialysis hypoglycemia frequently occurs and is a main factor interfering with the delivery of dialysis. As a result, it reduces the quality of life in patients undergoing hemodialysis. The long-acting insulin analogue glargine provides peakless, continuous release over 24 h that approximates a normal basal insulin pattern. Because it has no peak, its use in patients with diabetes undergoing hemodialysis would hypothetically be useful. Specifically, patients would be able to avoid intra-hemodialysis hypoglycemia without the necessity of skipping insulin administration on the day of hemodialysis and achieving adequate glucose control on other days. We recently experienced six cases that switched from treatment with intermediate-acting insulin to a long-acting insulin analogue, which provided better glycemic control by reducing hypoglycemia risk. Limited data are available in the literature concerning insulin analogue usage in patients with diabetes undergoing hemodialysis. Our experience suggests a large-scale prospective investigation is required on this issue. (Korean J Med 2012; 83:647-653)
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