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최환준,권준성,탁민성,Choi, Hwan-Jun,Kwon, Joon-Sung,Tark, Min-Seong 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.6
Purpose: The fingertip is the most commonly injured part of the hand and its injury frequently results in avulsion or crushing of a segment of the nail bed and fracture of the distal phalangeal bone. Restoration of a flat and smooth nail bed is essential for regrowth of a normal nail, which is important not only for cosmetic reasons but also for tactile capability of the fingertip. It is also anatomical reduction of the distal phalanx to promote patient's cosmetics and prevent nail bed deformity. Absence or no replacement of the nail plate results in obliterated proximal skin fold. When the avulsed nail plate cannot be returned to its anatomic position or when it is absent, we use a synthetic material for splinting the nail bed and alternative reductional method for distal phalangeal bone fracture, especially, instead of hardwares. Methods: From January of 2006 to June of 2009, a total of ten patients and fourteen fingers with crushing or avulsion injuries of the fingertip underwent using the artificial nails for finger splint. We shaped artificial nails into the appropriate sizes for use as fingernail plates. We placed them under the proximal skin fold and sutured to the fold proximally and to the lateral and medial edges of the nail bed or to the distal fingertip. Our splints were as hard as K-wire and other fixation methods and more similar to anatomic nail plates. Artificial nails were kept in place for at least 3 weeks. Results: No artificial nail related complication was noted in any of the ten cases. No other nail fold or nail bed complications were observed, except for minor distal nail deformity because of trauma. Conclusion: In conclusion, in order to secure the nail bed after injury and reduce the distal phalangeal bone fracture, preparing a nail bed splint from a artificial commercial nail is a cheap and effective method, especially, for crushed or avulsion injuries of the fingertip.
중국산 햄스터 난소세포로부터 활성형 Angiopoietin-1 생산에 관한 배양액 pH의 효과
정주영(Joo-Young Chung),권준성(Jun-Sung Kwon) 산업기술교육훈련학회 2014 산업기술연구논문지 (JITR) Vol.19 No.4
The effect of culture pH on cell growth and active Angiopoietin-1 production from the recombinant Chinese hamster ovary(CHO) cells was investigated. The cells in the bioreactor were incubated at different pH conditions(6.8, 7.0, 7.2 and 7.4). Specific growth rate decreased at lower culture pH while cell viability remained constant for a longer culture time. Consistently, glucose consumption and lactate production were also reduced at lower culture pH. In contrast to cell growth, expression level of active Angiopoietin-1 dramatically increased by lowering pH. In addition, Western blotting experiment at non-reduced and reduced condition showed that production of active Angiopoietin-1 forms significantly increased at lower pH. These results suggest that lowering culture pH may significantly improve production of biologically active Angiopoietin-1 from CHO cells.
증례 : 감염 ; 위절제술 후 Streptococcus mitis에 의한 비장 Botryomycosis 1예
한양희 ( Yang Hee Han ),이상진 ( Sang Jin Lee ),권준성 ( Jun Sung Kwon ),최규호 ( Kyoo Ho Choi ),김문호 ( Moon Ho Kim ),송은희 ( Eun Hee Song ),강길현 ( Gil Hyun Kang ) 대한내과학회 2015 대한내과학회지 Vol.88 No.5
Botryomycosis는 과립상 물질을 형성하는 만성 화농성 육아종 감염 질환이고 세균이 원인이며 조직학적으로 진균종, 방선균균종, 방선균증과 감별된다. Botryomycosis의 발생에 있어 세균의 독성에 대한 숙주의 국소적인 면역체계 이상이 원인이 될 수 있으나 아직 명확하게 밝혀진 것은 없다. 내장형 botryomycosis는 비특이적인 증상을 보이고 특징적인 방사선 소견이 없어 종양으로 오진되기도 하므로 진단에 주의를 요한다. 지금까지 전 세계적으로 사람에서 발생한 botryomycosis는 200예 이상의 보고가 있었으나 비장을 침범한 사례는 2예밖에 없었으며 우리나라에서 보고된 증례는 없었다. 이에 저자들은 면역 기능이 정상인 53세 여자에서 위암진단 후 시행한 위절제술에서 합병된 Streptococcus mitis에 의한 botryomycosis의 비장 침범 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Botryomycosis is an uncommon chronic suppurative bacterial infection of the skin and visceral organs seen primarily in immunocompromised patients. Here, we report a case of splenic botryomycosis caused by Streptococcus mitis in a 53-year-old immunocompetent woman with a history of distal gastrectomy for advanced gastric cancer. (Korean J Med 2015;88:608-611)
증례 : 신장; 혈액 투석 환자에서 발생한 경화성 피막성 복막염 1예
송윤아 ( Yun A Song ),김은정 ( Eun Jung Kim ),권준성 ( Jun Sung Kwon ),김수희 ( Su Hee Kim ),최건무 ( Kun Moo Choi ),엄대운 ( Dae Woon Eom ),송경일 ( Kyung Il Song ) 대한내과학회 2013 대한내과학회지 Vol.85 No.6
저자들은 B형 간염에 의한 간경화가 있는 혈액투석 환자에서 반복적인 복수 및 복막염의 증상이 발생하여 경화성복막염 의심하에 개복술로 이를 확진하였고 이후 스테로이드 치료로 호전된 경화성 피막성 복막염을 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Encapsulating peritoneal fibrosis (EPF) is a serious, uncommon complication of chronic peritoneal dialysis. However, it is rare in hemodialysis patients. EPF is characterized by peritoneal membrane inflammation followed by peritoneal membrane fibrosis and encapsulation. The etiology is unclear, but inflammation of the deteriorated peritoneum causes peritoneal fibrosis. We present a case of EPF that occurred in a 29-year-old man with hepatitis B-associated liver cirrhosis with ascites that was treated solely with hemodialysis. We managed this patient surgically and then medically with prednisolone. To our knowledge, this is the first such case in Korea, so we report this case with a literature review. (Korean J Med 2013;85:629-633)
즐례 : 저칼슘혈증을 동반한 급성 화농성 갑상선염 1예
유승진 ( Seung Jin Yoo ),심명숙 ( Myoung Sook Shim ),김원준 ( Won Jun Kim ),김은정 ( Eun Jung Kim ),오광훈 ( Kwang Hoon Oh ),이제훈 ( Je Hoon Lee ),권준성 ( Jun Sung Kwon ) 대한내과학회 2014 대한내과학회지 Vol.86 No.1
저자들은 급성 화농성 갑상선염을 진단하고 항생제, 칼슘 제 및 1α-OH-D3 투여로 임상증상 및 부갑상선기능, 저칼슘 혈증이 호전된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. We report a case of acute suppurative thyroiditis complicated by idiopathic hypoparathyroidism. The patient was a 49-year-old female who visited our clinic with a painful goiter on the left lobe of the thyroid gland. She was hypocalcemic, which was accompanied unusually by acute suppurative thyroiditis. She also suffered from tetany of both hands and legs. She had undergone a right subtotal thyroidectomy at another hospital 23 years previously due to a benign thyroid nodule. Intact parathyroid hormone (PTH) levels were increased, but other laboratory findings were normal. No special treatment was administered for the acute suppurative thyroiditis, except antibiotics, to observe its natural course. Her PTH levels decreased and serum calcium returned to normal. The complication of acute suppurative thyroiditis suggested the possible involvement of idiopathic hypoparathyroidism. (Korean J Med 2014;86:79-83)