http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
ACE 유전자 다형성에 따른 일회적 탈진성 운동이 혈중 SOD와 MDA에 미치는 영향
권순욱(Kwon Sun Ug),박인성(Park In Seong) 한국사회체육학회 2003 한국사회체육학회지 Vol.19 No.2
It is anticipated that ACE level would be related to antioxidant system by affecting angiotensin Ⅱ. Since there are little studies on this point, the role of polymorphism of ACE gene about oxidative stress should be identified. The purpose of this study, therefore, is to identify the relationship between polymorphism of ACE gene and antioxidant system. In order to perform this study, 39 health adults were grouped by their ACE gene, which are DD, ID andⅡ types, and performed maximal exercise. By observing SOD, MDA values at pre, post and recovery 30 minute, the adjustment effect of exercise can be studied. These results, therefore, can present the basis to the field of exercise prescription and exercise physiology. Each gene groups which were grouped by ACE gene polymorphism performed maximal exercise and their values of SOD and MDA were compared by two factors genotype and time. Based on the results of blood analysis, repeated-measures ANOVA was performed and the major results are as follows . 1)There was an interaction effect between genotypes and times in SOD. Only DD genotype showed different actions as times went when compared the rest of types. This can cause an interaction effect. 2) There was an interaction effect between genotypes and times in MDA. When DD genotype compared to the rest of genotype(ID,Ⅱ), they showed a quite different trend about times. Its value decreased at post exercise and increase at recovery 30. As a result of this conclusion. DD genotype showed different blood SOD, MDA trend as times went when compared the rest of genotype. This was considered to be caused by DD genotype`s high blood ACE level and DD ge notype needed antioxidant adaptation through regular exercise.
흑색진균에서 중합효소 연쇄반응 및 제한효소 절편길이 다형성을 이용한 Ribosomal DNA 분석
서무규 ( Seo Mu Gyu ),김연진 ( Kim Yeon Jin ),권순욱 ( Kwon Sun Ug ),김정철 ( Kim Jeong Cheol ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.11
N/A Background : There are three kinds of diseases caused by dematiaceous fungi : chromoblastomycosis, phaeohyphomycosis, and eumycotic mycetoma. The dematiaceous fungi have been identified and classified by morphological, biochemical and physiological tests. Recently molecular analysis has been introduced to the field of medical mycology. Objective : Ribosomal DNA gene analysis of dematiaceous fungi using polymerase chain reaction(PCR)-restriction fragment length polymorphism(RFLP) is investigated. Methods : The dematiaceous fungal strains studied were eight clinical isolates of chromoblastomycosis and phaeohyphomycosis agents(3 strains of Fonsecaea pedrosoi, 2 strains of Exophiala dermatitidis, 1 strain of Exophiala jeanselmei, 1 strain of Phialophora verrucosa, 1 strain of Rhinocladiella aquaspersa) and 4 standard strains(F. pedrosoi IFM 4889, E. dermatitidis IFM 4828, P. verrucosa IFM 4928, R. aquaspersa IFM 4930). Total twelve strains of dematiaceous fungi were cultured on Sabouraud dextrose broth and their DNA was extracted by bead-beating method. PCR-RFLP of ribosomal gene small subunit(SSU rDNA) and internal transcribed spacer(ITS)1-ITS2 ribosomal regions using the primer pairs NS1-NS2 and ITS1-ITS4, respectively were done. Results : The PCR product obtained from the SSU rDNA amplification was of approximately 603 bp and restriction profile was clustered into two genetically heterogenous groups, the first one formed by F. pedrosoi and the second one formed by other dematiaceous fungi. In contrast, the amplifiedb PCR products of ITS regions ranged in sized from 580 to 620 bp and restriction profile was clustered into five genetically heterogenous groups and it can be possible to differentiate dematiaceous fungi. But one clinical isolate of F. pedrosoi showed intra-specific variability. Conclusion : The PCR-RFLP analysis of SSU rDNA and ITS regions provided useful information for identification and classification of dematiaceous fungi. (Korean J Dermatol 2003;41(11) : 1478∼1486)
제5차 대한간학회 춘계학술대회 초록집 : 간경변증환자에서 급성 정맥류 출혈의 치료로써 Somatostatin과 Vasopressin의 효과에 대한 무작위 전향적인 비교연구
이헌영 ( Lee Heon Yeong ),이헌주 ( Lee Heon Ju ),이승민 ( Lee Seung Min ),이경태 ( Lee Gyeong Tae ),김준환 ( Kim Jun Hwan ),권순욱 ( Kwon Sun Ug ),이병석 ( Lee Byeong Seog ),김남재 ( Kim Nam Jae ) 대한간학회 1999 Clinical and Molecular Hepatology(대한간학회지) Vol.5 No.1(S)