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- 저자 : 구양수(Yang Soo Ku) (검색결과 5 건)
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고지방혈중에서 Bezafibrate ( Bezalip(R)) 의 효과에 대한 연구
이웅구(Woong Ku Lee),김병옥(Byung Ok Kim),조현명(Hyeon Myeong Cho),장양수(Yang Soo Jang),정남식(Nam Sik Chung),심원흠(Won Heum Shim),조승연(Seung Yun Cho),김성순(Sung Soon Kim),양주영(Joo Young Yang) 대한내과학회 1991 대한내과학회지 Vol.40 No.6
N/A Among the risk factors associated with coronary artery disease, hyperlipidemia is one of the most important. Bezafibrate has been shown to effctively reduce elevated levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) in hyperlipidemia. It has also been claimd to be particularly effective in increasing high-density lipoprotein (HDL) concentrations. In the present study, 22 hyperlipidemic patients were investigated before and after 8 weeks treatment with bezafibrate (300 mg to 400 mg daily) in an effort to clarify futher the effects and side effects of the drug. In the group of 9 patients with hypertriglyceridemia (TG level>230mg%), the serum triglycerides decreased by 63%(p<0.01) and the HDL cholesterol increased by 45%, (p<0.01) corresponding to a significant reduction of total cholesterol/HDL cholesterol ratio. In the group of 9 patients with hypercholesterolemia (cholesterol level > 240 mg%), the total cholesterol decreased by 20% (p<0.01), the LDL cholesterol decreased by 25% (p<0.01) and HDL cholestrol increased by 44% (p<0.01) corresponding to a significant reduction of LDL/HDL ratio. In the group of 4 patients with combined hyperlipidemia (TG level > 230 mg% and cholesterol level > 240 mg%), the total cholesterol decreased by 23% (p<0.01), the serum triglyceride decreased by 62% (p<0.01) and the HDL-cholesterol increased by 19% (p<0.05) corresponding to a significant reduction of total cholesterol/HDL cholesterol ratio. In the total of 22 patients, the total cholesterol decreased by 15% (p<0.05), the serum triglyceride decreased by 59% (p<0.01) and the HDL cholesterol increased by 39% (p <0. 01) corresponding to a significant reduction of total cholesterol/HDL cholesterol ratio. No subjective side effects were noted from the drug, except in one patient with mild gastrointestinal symptoms. In conclusion, it was noted that the bezafibrate was an effective and safe drug useful in the treatment of hyperlipidemia in Korean adult patients.
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16 MDCT를 이용한 CT Urography의 유용성
김동수(Dong Soo Kim),강화원(Hwa Won Kang),임상묵(Sang Muk Im),구양수(Yang Su Ku),이강우(Kang Woo Lee),최창한(Chang Han Choi) 대한CT영상기술학회 2005 대한CT영상기술학회지 Vol.7 No.1
Purpose To evaluate the usefulness of computed tomography urography with 16-channel multidetecter computed tomography in patients with urinary track disease. Materials and Methods IN 28 patients who underwent CT urography from May 2004 to December 2004. The clinical symptoms of these patients include; renal donors or hematuria, which were clinically suggestive of urinary system disorders. All studies were performed on a siemens sensation 16 scanner with 16mm detectors. CT scans were obtained on a unenhanced, arterial phase, 1,3,5 minites with the following technique : a collimator of 5mm a pitch of 1, and 3d reconstrutions at a thickness of 2mm with intervals of l.5mm. Intravenous administered of the normal saline 50 ml immediately after injecting contrast medium(at a rate of 3 ml/sec). Results Of these 28 patients,(9men and 19 women, age ranged from 20 to 79 years old, mean age 44.8 years)l4 patients(46.7%) were proven to have no 뮤normal disease, 4 patients(13.4%) were with renal stones or hydronephrosis, and there were 10 patients(40.9%) of other urinary system disorders. Conclusion CT urography is a very useful modality to evaluate kidny-transeplatation donors, hematuria and flank pain in the patients with urinary track disease
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FAI 환자의 30 Pelvic CT MPR 영상의 유용성
김종희(Jong Hee Kim),이득열(Deuk Yeol Lee),이광원(Gwang Won Lee),구양수(Yang Soo Ku),조영기(Yeong Gi Cho) 대한CT영상기술학회 2011 대한CT영상기술학회지 Vol.13 No.2
최근 증가하고 있는 FAI(femoroacetabular impingement syndrome) 영상진단에 3D Pelvic CT가 임상적으로 많이 시도되고 있다. 이에 본 연구는 CT MPR 영상들을 비교, 분석하여 FAI 진단에 있어 유용성을 알아보고자 한다. 대상 및 방법 2009년 7월부터 2010년 3월까지 본원으로 내원한 환자 중 FAI로 진단된 환자(Cam형 or Mixed형) 남자 14명, 여자 6명 총 20명을 대상으로 하였다. 방법은 일반 X-ray Hip joint axiolateral 영상과 3D Pelvic CT의 Oblique axial plane MPR영상과 Radial plane MPR 영상의 alpha angle을 측정하여 비교 분석하였다. 결과 일반 X-ray Hip joint axiolateral 영상과 3D Pelvic CT의 Oblique axial plane MPR 영상, 그리고 Radial plane MPR 영상의 alpha angle을 측정하여 비교, 분석한 결과 평균값이 각각 69.9° 72.8°, 75.4°로 Radial plane MPR 영상의 alpha angle이 75.4°로 가장 높게 측정되었다. 결론 일반 X-ray의 Hip joint axiolateral 영상에서는 정확한 자세와 각도로 촬영하여야만 의미있는 측정치를 얻을 수 있었으며, 3D Pelvic CT의 Oblique axial plane MPR의 alpha angle은 Radial plane MPR 영상보다 평균 2.6° 작게 측정되어 FAI가 저 평가되었다. 따라서 Radial plane MPR 영상이 더욱 유용하므로 FAI의 진단에 효율적이라 사료된다. I. Purpose Three-dimensional pelvic CT is often attempted clinically in the radiological diagnosis of FAI (femoroacetabular impingement syndrome), the incidence of which is increasing recently. Thus, this study purposed to examine the usefulness of CT MPR images in the diagnosis of FAI through comparative analysis of such images. II. Meterial and Methods The subjects of this study were 20 patients (14 males and 6 females) diagnosed with FAI (cam type or mixed type) sampled from patients who had visited the hospital during the period from July 2009 to March 2010. As to the method, we measured and compared the alpha angle in ordinary X-ray hip joint axiolateral images, and in oblique axial plane MPR images and radial plane MPR images of 3D Pelvic CT. III. Result When che alpha angle was measured and compared for ordinary X-ray hip joint axiolateral images, and oblique axial plane MPR images and radial plane MPR images of 3D Pelvic CT, the mean alpha angle was 69.9°, 72.8° and 75.4°, respectively, so it was large&t as 75.4° in radial plane MPR images. IV. Conclusions In ordinary X-ray hip joint axiolateral images, meaningful measurements can be obtained only when the position and angle of imaging are accurated, in addition, the mean alpha angle in oblique axial plane MPR images of 3D Pelvic CT was 2.6° smaller than that in radial plane MPR images, and as a result, FAI was underestimated. Accordingly, radial plane MPR images are more useful and thus should be considered in the diagnosis of FAI.
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New-onset angina 군과 만성협심증군의 비교 관찰
조승연,박금수,정남식,장양수,심원흠,이웅구 대한내과학회 1986 대한내과학회지 Vol.31 No.2
Fifity-five patients with new-onset angina(duration of symptoms ?l month) and 80 patients with chronic angina(duration of symptoms $gt;3 month) were reviewed to determine the differences of anatomic coronary artery disease. None patients with significant coronary artery disease of the (diagnosed at cardiac catheterization) had a history of prior myocardial infarction or congestive heart failure. There were no significant differences in distribution of age and sex, risk factors and left venticular function between patients with new-onset angina and those with chronic angina. In patients with new-onset angina, there was a similar high incidence of single vessel disease(53%,vs 49%) and slightly lower incidence of triple vessel disease(16% vs 26%) compared with those with chronic angina, but their differences were not statistically significant. A similar predisposition for disease of the LAD (left anterior descending artery) was found. in both groups. Thus patients with new-onset angina apparently have no distinguishing coronary angiographic features as compared with those with chronic angina.
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