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      • KCI등재

        나노 크기의 마그네타이트 입자를 이용한 자성 키토산 미소구체의 제조

        고상길(Sang Gil Ko),조준희(Jun Hee Cho),안양규(Yangkyu Ahn),송기창(Ki-Chang Song),최은정(Eun Jung Choi) 한국자기학회 2006 韓國磁氣學會誌 Vol.16 No.1

        Magnetite nanoparticles, which have been extensively used in many fields, were encapsulated with a natural polymer, chitosan, to improve their biocompatibility. We have synthesized magnetite (Fe₃O₄) nanoparticles using chemical coprecipitation technique with sodium oleate as surfactant. Nanoparticle size can be varied from 1.2 to 7.4 ㎚ by controlling the sodium oleate concentration. Magnetite phase nanoparticles could be observed from X-ray diffraction. Magnetic colloid suspensions containing particles with sodium oleate and chitosan have been prepared. High magnetic property chitosan-microsphere particles were prepared from oleatecoated magnetite suspension using spray method. The surface, and the morphology of the magnetic chitosan microsphere particles were characterized using optical microscope and scanning electron microscope. Magnetic hysteresis measurement were performed using a superconducting quantum interference device (SQUID) magnetometer at room temperature to investigate the magnetic properties of the chitosan microspheres including magnetite nanoparticles. The SQUID measurements revealed superparamagnetism of nanoparticles.

      • KCI등재

        의학적 응용을 위한 생체 고분자로 피복 된 자성 나노 입자와 미소구체의 제조

        고상길(Sang Gil Ko),조준희(Jun Hee Cho),안양규(Yangkyu Ahn),송기창(Ki-Chang Song),최은정(Eun Jung Choi) 한국자기학회 2006 韓國磁氣學會誌 Vol.16 No.4

        We have synthesized uniform nanometer sized magnetite particles using chemical coprecipitation technique through a sonochemical method with surfactant such as oleic acid. Magnetite phase nanoparticles could be observed from X-ray diffraction. Magnetite nanoparticles is surface phase morphology and biopolymer-microspheres for Application Medical. Magnetite nanoparticles coated biopolymer. Atomic Force Microscope (AFM) was used to image the coated nanoparticles. Magnetic colloid suspensions containing particles with sodium oleate, chitosan and β-glucan have been prepared. The morphology of the magnetic biopolymer microsphere particles were characterized using optical microscope. Magnetic hysteresis measurement were performed using a superconducting quantum interference device (SQUID) magnetometer at room temperature to investigate the magnetic properties of the biopolymer microspheres and magnetite coated biopolymer including magnetite nanoparticles. Magnetic Resonance (MR) imaging was used to investigate biopolymer coated nanoparticles and biopolymer microspheres.

      • KCI등재

        음향화학법을 이용한 아연페라이트 나노입자의 합성

        조준희,고상길,안양규,강건욱,안동현,최은정,Cho, Jun-Hee,Ko, Sang-Gil,Ahn, Yang-Kyu,Kang, Kun-Uk,An, Dong-Hyun,Choi, Eun-Jung 한국자기학회 2007 韓國磁氣學會誌 Vol.17 No.2

        계면활성제를 첨가한 음향화학적 침전법으로 두 가지 크기의 아연페라이트 나노입자를 합성하였다. 열분석장치(TGA/DSC)를 이용하여 열적 특성 및 결정화 온도를 조사하였고, 결정구조 확인을 위하여 X선 회절실험을 실시하였다. 제조된 입자는 $240^{\circ}C$ 부근에서 결정생성이 시작되었으며, 결정구조는 전형적인 스피넬 구조를 나타내었다. Scherrer식에 의해 측정된 입자의 크기는 11.2nm와 13.4nm이었다. SQUID를 통하여 자기적 성질을 분석한 결과, 작은 크기의 입자에 대한 방해온도 $T_B$(Blocking temperature)가 큰 입자의 경우보다 더 높게 나타났다. Ultrasonic irradiation in a solution during the chemical reaction may accelerate the rate of the reaction and the crystallization at low temperature. We have synthesized nanometer sized zinc ferrite particles using chemical co-precipitation technique through a sonochemical method with surfactant such as oleic acid. The thermal behaviour of the zinc ferrite was determined by the thermoanalytical techniques (TGA-DSC). Powder X-ray diffraction measurements show that the samples have the spinel structure. Magnetic properties measurement were performed using a superconducting quantum interference device (SQUID) magnetometer.

      • KCI등재

        음향화학법을 이용한 균일한 나노 자성체의 합성

        조준희(Jun Hee Cho),고상길(Sang Gil Ko),안양규(Yangkyu Ahn),송기창(Ki-Chang Song),최은정(Eun Jung Choi) 한국자기학회 2006 韓國磁氣學會誌 Vol.16 No.3

        Ultrasonic irradiation in a solution during the chemical reaction may accelerate the rate of the reaction and the crystallization at low temperature. We have synthesized nanometer sized magnetite particles using coprecipitation method, sonochemical method without surfactant, and sonochemical method with surfactant, in order to investigate the effect of ultrasonic irradiation and surfactant on the coprecipitates of metal ions. The size of the magnetite nanoparticles prepared by coprecipitation method, and sonochemical method without surfactant showed broad distributions. But we got uniform nanoparticles using a sonochemical method with oleic acid. The average size of the particles can be controlled by the ratio R = [H₂O]/[surfactant]. The size of the magnetite nanoparticles prepared by this method showed narrow distributions. We have characterized the nanoparticles using an X-ray diffraction (XRD), a superconducting quantum interference device (SQUID), and atomic force microscope (AFM). The size and distribution of the magnetite nanoparticles were measured by dynamic light scattering (DLS) method.

      • KCI등재

        키토산이 피복된 나노 크기의 자성체 분말 제조

        조준희(Jun Hee Cho),고상길(Sang Gil Ko),안양규(Yangkyu Ahn),송기창(Ki-Chang Song),최은정(Eun Jung Choi) 한국자기학회 2006 韓國磁氣學會誌 Vol.16 No.1

        Magnetic nanoparticles can be used for a variety of biomedical applications. They can be used in the targeted delivery of therapeutic agents in vivo, in the hyperthermic treatment of cancers, in magnetic resonance (MR) imaging as contrast agents and in the biomagnetic separations of biomolecules. We have synthesized magnetite (Fe₃O₄) nanoparticles using chemical coprecipitation technique with sodium oleate as surfactant. Nanoparticle size can be varied from 2 to 8 ㎚ by controlling the sodium oleate concentration. Magnetite phase nanoparticles could be observed from X-ray diffraction. Magnetic colloid suspensions containing particles with sodium oleate and chitosan have been prepared. Nanoparticles, both oleate-coated and chitosan-coated, have been characterized by several techniques. Atomic force microscope (AFM) was used to image the coated nanoparticles. Magnetic hysteresis measurement were performed using a superconducting quantum interference device (SQUID) magnetometer at room temperature to investigate the magnetic properties of the magnetite nanoparticles. The SQUID measurements revealed superparamagnetism of nanoparticles.

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