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동종유래각질세포(Cultured Allogenic Keratinocytes, Kaloderm<sup>®</sup>)를 이용한 부분층 피부 결손의 치료
서상원,장충현,조민수,홍윤기,전세화,Seo, Sang Won,Chang, Choong Hyun,Cho, Min Su,Hong, Yoon Gi,Jeon, Sae Wha 대한외상학회 2007 大韓外傷學會誌 Vol.20 No.1
Purpose: Grafting with autograft skin remains the most effective method for treating skin defects. When insufficient donor sites are present or patients are afraid of the operation, a skin graft is impossible. Cultured allogenic keratinocytes speed wound healing by providing cover and by producing growth factors and extracellular matrix protein. We report an application of cultured allogenic keratinocytes ($Kaloderm^{(R)}$, Tegoscience, Seoul, Korea) in the treatment of an acute partial thickness skin defect. Methods: From March 2005 to January 2006, 20 patients with a partial thickness skin defect were treated with cultured allogenic keratinocytes. The wound was covered with a sheet of cultured allogenic keratinocytes and ointment with $Bactigras^{(R)}$ gauze. The wound was inspected every two or three days. We regarded completion of epithelialization as wound healing. Results: The mean period between time of injury and time of $Kaloderm^{(R)}$ application was 7.5 days. The time taken from application of $Kaloderm^{(R)}$ to complete closure of the wounds was 7.2 days. Conclusion: In view of the favorable outcome, cultured allogenic keratinocytes are safe and effective biologic dressing materials for use in the treatment of open wounds.
비선형 특징추출 기법에 의한 머리전달함수(HRTF)의 저차원 모델링 및 합성
서상원,김기홍,김현석,김현빈,이의택,Seo, Sang-Won,Kim, Gi-Hong,Kim, Hyeon-Seok,Kim, Hyeon-Bin,Lee, Ui-Taek 한국정보처리학회 2000 정보처리논문지 Vol.7 No.5
For the implementation of 3D Sound Localization system, the binaural filtering by HRTFs is generally employed. But the HRTF filter is of high order and its coefficients for all directions have to be stored, which imposes a rather large memory requirement. To cope with this, research works have centered on obtaining low dimensional HRTF representations without significant loss of information and synthesizing the original HRTF efficiently, by means of feature extraction methods for multivariate dat including PCA. In these researches, conventional linear PCA was applied to the frequency domain HRTF data and using relatively small number of principal components the original HRTFs could be synthesized in approximation. In this paper we applied neural network based nonlinear PCA model (NLPCA) and the nonlinear PLS repression model (NLPLS) for this low dimensional HRTF modeling and analyze the results in comparison with the PCA. The NLPCA that performs projection of data onto the nonlinear surfaces showed the capability of more efficient HRTF feature extraction than linear PCA and the NLPLS regression model that incorporates the direction information in feature extraction yielded more stable results in synthesizing general HRTFs not included in the model training.
Zinc 함수 여기신호를 이용한 분석-합성 구조의 초 저속 음성 부호화기
서상원,김종학,이창환,정규혁,이인성,Seo Sang-Won,Kim Jong-Hak,Lee Chang-Hwan,Jeong Gyu-Hyeok,Lee In-Sung 한국음향학회 2006 韓國音響學會誌 Vol.25 No.6
본 논문에서는 1.2 kbps 의 전송률을 가지는 초 저속 음성 부호화기를 위한 방법과 구조를 제안한다. ZFE-CELP (Zinc Function Excitation-Code Excited Linear Prediction) 음성 부호화기는 선형예측 분석 후, 추출된 잔여 신호가 유성음일 경우 Zinc Function을 이용하여 부호화하고, 무성음일 경우에는 CELP 구조를 이용하여 부호화한다. 또한 Super-frame (40ms) 의 영향으로 발생하는 하모닉의 불연속 문제를 해결하기 위해 오버 샘플링을 이용한 선형 위상 합성 기법을 이용하고 Zinc 함수의 정확한 표준파형을 추출하기 위하여 분석-합성 구조를 제안한다. 제안된 초 저속음성 부호화기의 성능을 2.4 kbps의 MELP (Multi Pulse Linear Prediction) 부호화기 및 1.9kbps의 ZFE-PWI (Zinc Function Excitation-Prototype Waveform Interpolation) 음성 부호화기와 비교하였다 제안된 부호화 방법은 19kbps ZFE-PWI 부호화기와 유사한 성능을 보이는 것을 확인하였다. This paper proposes a new Digital Reverberator that models Analog Helical Coil Spring Reverberator for guitar amplifiers. While the conventional digital reverberators are proposed to provide better sound field mainly based on room acoustics, no algorithm or analysis of digital reverberators those model Helical Coil Spring Reverberator was proposed. Considering the fact that approximately $70{\sim}80$ percent of guitar amplifiers are still with Helical Coil Spring Reverberator, research was performed based not on Room Acoustics but on Helical Coil Spring Reverberator itself as an effector. After performing simulations with proposed algorithm, it was confirmed that the Digital Reverberator by proposed algorithm provides perceptually equivalent response to the conventional Analog Helical Coil Spring Reverberators.
지혜 깊어지는 건강_50대를 지켜라 - 원인을 알면 예방할 수 있는 치매
서상원,Seo, Sang-Won 한국건강관리협회 2011 건강소식 Vol.35 No.10
치매(dementia)는 라틴에게서 유래된 말로서 '정신이 없어진 것' 이라는 의미를 갖고 있다. 태어날 때부터 지적 능력이 모자라는 경우를 정신지체(mental retardation)라고 부르는 반면, 치매는 후천적인 뇌질환이다. 즉, 정상적으로 생활해 오던 사함이 후천적인 뇌 손상으로 인하여 기억력, 언어능력, 방향감각, 판단력 등의 인지기능을 잃어가는 것이다. 또한 이런 인지 기능 장애가 심각하여 일상생활에 상당한 지장이 나타날 때 치매라고 한다.
Pull-up 운동 시 그립 두께에 따른 근활성도의 변화
서상원 ( Sang-won Seo ),고성식 ( Sung-sik Ko ),안근옥 ( Keun-ok An ) 한국운동생리학회(구 한국운동과학회) 2021 운동과학 Vol.30 No.1
PURPOSE: There are various variables such as exercise posture, exercise intensity, number of repetitions, and rest time of training for muscle strength development, and these variables are intended to stimulate muscle activity. The purpose of this study was to examine the effects of muscle activation according to grip thickness in pull-up exercise. METHODS: Eleven healthy men were randomly crossover design assigned to pull-up exercise (concentric: 1-s, eccentric: 1-s, 2-s/repetition) to failure. Surface electromyography (EMG) was recorded from the forearm flexors/extensors, biceps brachii, trapezius middle/ lower and latissimus dorsi for muscle activation. Using the resulting EMG data, which were filtered of electromyogram artifacts, we calculated the root mean squares (RMS). RESULTS: Dependent-sample t-test produced a result, muscle activity in forearm flexors (p<.01), biceps brachii (p<.01), trapezius middle (p<.01), trapezius lower (p<.01) and latissimus dorsi (p<.05) were significantly increased at thick grip compared to normal grip in pull-up exercise. CONCLUSIONS: This study suggested that the thicker the grip, the higher the muscle activation. Using a grip thickness as one of the variables for training programs is considered as a method to stimulate muscle activity.