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Low Power 10-b 250Msample/s CMOS Cascaded Folding and Interpolating A/D Converter
CUI, Zhi-Yuan,JIN, Yong-Gao,KIM, Nam-Soo,CHOI, Ho-Yong The Institute of Electronics, Information and Comm 2009 IEICE transactions on electronics Vol.92 No.8
<P>This paper introduces a new folding amplifier in a folding and interpolating 10-b ADC. The amplifier consists of current mirrors and differential stages. Only one current source is exploited in cascaded differential pairs, which reduces the power consumption significantly. In the folding circuit, the interpolation is implemented with a current division technique. An experiment of the amplifier in 10-b folding signal has been integrated in a single-poly four-metal 0.35µm CMOS process. The simulation in 10-b folding ADC shows that power consumption is 225mW at the sampling speed of 250Msample/s and the power supply of 3.3V. The preliminary experiment indicates the current steering folder and digital bits operate as expected.</P>
Study and Application of Evaluation Hierarchy on Power Supply Capability of Distribution Network
Cui, Yan-Yan,Wei, Tao,Chen, Hai,Li, Zhi-Yong 대한전기학회 2012 The Journal of International Council on Electrical Vol.2 No.4
Against the lack of quantitative assessment method on power supply capability of distribution network, evaluation hierarchy on power supply capability of distribution network is proposed. In addition to some common indices, the hierarchy includes some new indices such as "load balancing degree of main transformers, substations and lines", "coordination of power supply between high and medium voltage network", "matching degree of power supply and transmission capability" etc. Besides that, evaluation process is put forward. In accordance with urban and rural areas, the respective adaptive scoring standards and weight values are given. The power supply capabilities of distribution network of two districts in Chongqing, China are evaluated based on the hierarchy proposed in this paper. The example proves that the method and evaluation hierarchy can not only evaluate the power supply of distribution network scientifically, find the weak link, but also guide the planning and construction of network.
A sequential triggering technique in cascaded current source for low power 12-b D/A converter
Cui, Zhi-Yuan,Choi, Ho-Yong,Cho, Tae-Won,Kim, Nam-Soo Emerald Group Publishing Limited 2011 Microelectronics international Vol.28 No.1
<B>Purpose</B> - The purpose of this paper is to introduce a low power digital-to-analog converter (DAC) by using a sequential triggering technique in cascaded current source. <B>Design/methodology/approach</B> - The block of current cell consists of current switch and source. A sequential switching on process is implemented with the current triggering technique in source. An experiment of 12-b 150-MS/s DAC has been integrated in a single-poly four-metal 0.35?µm CMOS process. <B>Findings</B> - Compared with conventional cell array in 12-b 150-MS/s DAC, the proposed cell array shows that more than 30 percent of power consumption is reduced in full digital bit operation with allowable linearity error of 0.4 LSB. <B>Originality/value</B> - This paper presents a new operation method of cell array in a current-steering digital-to-analog converter (DAC) to reduce the power consumption significantly.
CHISELED NICKEL HYDROXIDE NANOPLATES GROWTH ON GRAPHENE SHEETS FOR LITHIUM ION BATTERIES
LEI-LEI TIAN,XIAN-YONG WEI,QUAN-CHAO ZHUANG,CHAO WU,RUI-LUN XIE,ZHI-MIN ZONG,YONG-LI CUI,SHI-GANG SUN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.6
The morphologies and structures of Ni(OH)2–graphene hybrid materials were tailored by using different mineralizers in this work. It was revealed that the synergic effects of the highly oxidized graphene sheets and the mineralizers played a crucial role in controlling the morphology and structure of the nanocomposites, and Na2CO3 is a very effective mineralizer for growing chiseled 2D nanoplates of Ni(OH)2 on graphene sheets. When produced with NaOH, fragmental Ni(OH)2 crystals with irregular shapes erratically decorated on graphene sheets. In contrast, chiseled Ni(OH)2 hexagonal nanoplates grown on graphene sheets were obtained when Na2CO3 was used as the mineralizer. These unique 2D–2D nanoarchitectures with higher contact area between the nanocrystals and graphene substrate can increase the interfacial interaction and then efficiently improve the structural stability of the composite material, thus exhibiting an enhanced Li storage capacity and excellent cycling performance of 562 mAh g-1 after the 36th cycle.
Association of TERT rs2736098 Polymorphism with Cancer Risk: a Meta-analysis
Zhang, Xiao-Jing,Xu, Zhi,Gong, Yong-Ling,Tang, Cui-Ju,Chen, Jin-Fei Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Studies have reported an association between the TERT rs2736098 single nucleotide polymorphism (SNP) and cancer susceptibility, but the results remain inconclusive. Toprovide a more precise estimation of the relationship, a meta-analysis of 8 published studies including 8,070 cases and 10,239 controls was performed. Stratification by sample size, genotyping method, source of controls and ethnicity were used to explore the source of heterogeneity. In the overall analysis, no significant association was found between the TERT rs2736098 polymorphism and cancer risk. However, the result showed the rs2736098 was significantly associated with an increased cancer risk and the heterogeneity was effectively decreased for homozygote comparison by removal of two studies: OR = 1.337 (95% CI = 1.183-1.511; Pheterogeneity = 0.087). In the subgroup analysis by ethnicity, a significantly increased risk of cancers was found among Asians (OR = 1.413, 95% CI = 1.187-1.683 for AA versus GG). Our meta-analysis did not show that the TERT rs2736098 plays an important role in cancer risk. More studies with larger sample size and well-matched controls are needed to confirm the findings.
Overexpression of Cyclooxygenase-1 Correlates with Poor Prognosis in Renal Cell Carcinoma
Yu, Zu-Hu,Zhang, Qiang,Wang, Ya-Dong,Chen, Jing,Jiang, Zhi-Mao,Shi, Min,Guo, Xin,Qin, Jie,Cui, Guang-Hui,Cai, Zhi-Ming,Gui, Yao-Ting,Lai, Yong-Qing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
The aim of this study was to evaluate expression of COX-1 in renal cell carcinoma (RCC) and its prognostic value. mRNA of COX-1 was detected in 42 paired RCC and adjacent normal tissues with quantitative realtime polymerase chain reaction (qRT-PCR). Expression of COX-1 was also evaluated in 196 RCC sections and 91 adjacent normal tissues with immunohistochemistry. Statistical analysis was performed to assess COX-1 expression in RCC and its prognostic significance. The results of qRT-PCR showed mRNA levels of COX-1 in RCC tissues to be significantly higher than that in adjacent normal tissues (p < 0.001). Immunohistochemical assays also revealed COX-1 to be overexpressed in RCC tissues (p < 0.001). Statistical analysis demonstrated high expression of COX-1 was correlated with tumour size (p = 0.002), pathological stage (p = 0.003), TNM stage (p = 0.003, 0.007, 0.027, respectively), and tumour recurrence (p < 0.001). Survival analysis indicated patients with high expression of COX-1 had shorter survival time (p < 0.001), and COX-1 was an independent predictor. This is the first study to reveal overexpression of COX-1 in RRC and point to use as a prognostic marker in affected patients.
수평 구조의 MOS-controlled Thyristor에서 채널에서의 길이 및 불순물 농도에 의한 스위칭 특성
김남수,최지원,이기영,주병권,정태웅,Kim, Nam-Soo,Cui, Zhi-Yuan,Lee, Kie-Yong,Ju, Byeong-Kwon,Jeong, Tae-Woong 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.1
The switching characteristics of MOS-Controlled Thyristor(MCT) is studied with variation of the channel length and impurity concentration in ON and OFF FET channel. The proposed MCT power device has the lateral structure and P-epitaxial layer in substrate. Two dimensional MEDICI simulator and PSPICE simulator are used to study the latch-up current and forward voltage-drop from the characteristics of I-V and the switching characteristics with variation of channel length and impurity concentration in P and N channel. The channel length and N impurity concentration of the proposed MCT power device show the strong affect on the transient characteristics of current and power. The N channel length affects only on the OFF characteristics of power and anode current, while the N doping concentration in P channel affects on the ON and OFF characteristics.
Mechanical evaluation of polymer microneedles for transdermal drug delivery: In vitro and in vivo
Rui Xuan Liu,Yu Ting He,Ling Liang,Liu Fu Hu,Yue Liu,Rui-xing Yu,Bo Zhi Chen,Yong Cui,Xin Dong Guo 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.114 No.-
In this study, we reported two types of PMNs based on polylactic acid (PLA) and polyvinyl alcohol (PVA),respectively. Parafilm M film, porcine skin, and rats’ models were operated to evaluate the mechanicalproperties in vitro and in vivo to find optimal parameters for efficient insertion. Insertion depth was measuredusing Digital Force Gauge by changing insertion force and speed, respectively. Results showed thatincreasing the insertion force and speed used for PMNs application led to a significant increase in thedepth of insertion. A force of 18 N under a speed of 330 mm/min was the optimal condition for insertingPMNs array into ParafilmM film and porcine skin. In addition, PLA-MNs exhibited higher robustness andenhanced homogeneity in insertion depth compared with PVA-MNs, but PVA-MNs were able to reachmuch deeper insertion depth. Moreover, Sprague Dawley (SD) rat experiments confirmed the effectivenessof optimal insertion parameters for transdermal drug delivery. This study illustrated not only thedevelopment of novel PMNs but also the mechanical evaluation for the design of PMNs.
GGEx18의 ethyl acetate 분획물에 의한 고지방식이 비만 마우스의 식이효율과 혈중 leptin 농도에 미치는 영향
박기정,이희영,이혜림,윤미정,박선동,이용태,심지빈,최홍화,신순식,Park, Ki-Jeong,Lee, Hee-Young,Lee, Hye-Rim,Yoon, Mi-Chung,Park, Sun-Dong,Lee, Yong-Tae,Shen, Zhi-Bin,Cui, Hong-Hua,Shin, Soon-Shik 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1
Objectives : This study was designed to determine the effects of the GGEx18 ethyl acetate fraction(EF) on body weight gain, feeding efficiency ratio, and obesity-related factors in plasma as well as histology of liver and adipose tissues using high fat diet-fed male C57BL/6N obese mice. Methods : 8 weeks old, high fat diet-fed obese male mice were divided into 5 groups: C57BL/6N normal, control, EF(1), EF(2) and EF(3). After mice were treated with EF for 9 weeks, we measured body weight gain, food intake, feeding efficiency ratio, fat weight, plasma leptin and lipid levels. We also analysed histology of liver and adipose tissues on high fat diet-fed male C57BL/6N obese mice. Results : Compared with control, EF-treated mice had significantly lower body weight gain and feeding efficiency ratio. Consistent with the effects on body weight gain, EF significantly decreased the adipose tissue weight compared with control. Consistent with the effects on feeding efficiency ratio, EF significantly decreased plasma leptin concentrations compared with control. EF reduced the size of adipocytes as well as hepatic lipid accumulation compared with control. EF seems to be safe since not only the plasma levels of ALT and AST are within the normal range, but also EF did not show any toxic effects on organs. EF(3) was most effective among EF(1), EF(2), and EF(3) at doses of 25, 50, and 100 mg/kg, respectively. Conclusions : These results demonstrate that EF effectively reduces body weight gain, feeding efficiency ratio in high fat diet-fed obese mice, leading to the modulation of obesity. In addition, EF decreases the size of adipocytes and improves plasma lipids and controls hepatic lipid accumulation, suggesting that EF may act as a therapeutic agent for obesity.