ZnS:Mn/ZnS:TbF3 적층구조의 형광층을 이용한 TFEL 소자의 제작 및 그 특성

김영진,김기완,박경빈,김호운,배승춘,조기현 한국센서학회 1997 센서학회지 Vol.6 No.1

The thin-film eletroluminescent (TFEL) device having the stacked structure of ZnS:Mn/ZnS:TbF₃ has been fabricated. Insulate layers used (Pb,La)TiO₃ and SiO₂ thin films. The emission color was white. The TFEL device employing ZnS:Mn/ZnS:TbF₃(8000Å) stacked phosphor layers showed the threshold voltage of 78V_(rms). And the brightness of the TFEL device was 400 ㎼/㎠ at the applied voltage of 100V_(rms). The emission spectrum of TFEL device had a wavelength from 450nm to 620nm. The manufactured devices can be a practical use as a TFEL devices of red, green and blue by using the color filters.

중등도 및 중증고혈압에서 Nifedipine 설하투여의 강압효과에 관한 연구

김영훈,서순규,최인석,김열홍,안희권,심완주,노영무 대한내과학회 1986 대한내과학회지 Vol.31 No.5

In order to assess the efficacy of sublingual nifedipine in the acute treatment of moderate to severe hypertension, a single blind test was done in 30 patients, 10 males and 20 females, aged 40 to 76 years, with moderate to severe hypertension. The patients with mean sitting blood pressure(BP) of more than J40 mmHg received sublingual placebo, and BP and pulse rate(PR) were measured in sitting position 10,20 and 30 minutes after the sublingual placebo was given. The patients with post-placebo 30 minutes sitting mean BP of less than 13pmmHg were excluded from the study. The placebo treatment period was followed by the administration of 10mg of sublingual nifedipine, and BP and PR were measured 10,20,30 and 45 minutes after nifedipine was given. BP decreased with placebo treatment(p$lt;0. 01 by paired t-test, preplacebo vs. post-placebo 30 minutes). With sublingual nifedipine BP started to fall in 10 minutes and reached the lowest levels in 30 or 45 minu1es. The systolic BP decreased from 198.0±21.4mmHg to 159±20.4mmHg, diastolic BP from 122.5±13.0 mmHg to 103.2±14.4 mmHg and mean from 147.7±13.4 mmHg to 121.7±14.8 mmHg 45minutes after nifedipine(p$lt;0.01 by paired t-test). The average fall in systolic BP/diastolic BP/mean BP 45 minutes after nifedipine was 39/19/26 mmHg(p$lt;0. 001, by paired t-test). The maximal fall in systolic BP correlated better with pretreatment value(r=0.42) than the maximal fall in diastolic pressure(r=0.21), PR increased from 79±12 to 87±11/minute with nifedipine(p$lt;0.001, by paired t-test). Side effects were mild facial flushing(16.7%) and palpitation (3.3%). The findings suggest that a dose of 10mg of sublingual nifedipine is a simple, effective and safe method for the acute treatment of moderate to severe hypertension and can be used as a non-injecting alternative agent for the treatment of hypertensive emergency.

B 형 간염 Virus-Associated Hemophagocytic Syndrome 1 예

김진우,임경수,최영미,정인석,박두복,김호균,정영기 대한내과학회 1991 대한내과학회지 Vol.40 No.6

Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic generalized histiocytic proliferation with marked hemophagocytosis associated with systemic viral infections such as Epstein-Barr virus, cytomegalovirus, adenovirus, herpes virus. etc. High fever, liver dysfunction, coagulation abnormality, and peripheral blood cytopenias are characteristic findings. Hepatosplenomegaly, lymphadenopathy, bilateral pulmonary infiltrations, and skin rash are often present. We report a case of Hepatitis B virus-associated hemophagocytic syndrome with a brief review of literature.

Semi - continuous Culture 방법을 이용한 Condensed Tannin 의 한국재래산양 반추위 섬유소 분해 미생물의 활성에 미치는 영향

배귀석,이상석,최종원,박상엽,장문백,하종규,최일,배희동,김종민 한국낙농학회 1999 韓國酪農學會誌 Vol.21 No.2

14 일령 이유자돈을 위한 적정 LACTOSE : SUCROSE 비율 SUCROSE RATIO FOR THE PIGS WEANED AT 14 DAYS OF AGE

한인규,김진동,조원탁,한영근,이찬호,이기웅,박향숙 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.6

본 실험은 lactose에 대한 sucrose 대체가 14일령 조기 이유자돈의 성장에 미치는 영향을 알아보기 위하여 수행하였다. lactose와 sucrose의 적정비율을 결정하기 위해 평균체중 5.02±0.18 ㎏인 14일령 이유자돈 80두를 4처리 4반복, 반복당 5두씩 완전임의로 배치 하였으며, 처리구별 lactose와 sucrose의 비율은 각각 100:0(처리구 A), 75:25 (처리구 B), 50:50 (처리구 C), 25:75 (처리구 D) 및 0:100 (처리구 E)이었다. 이유초기 7일동안 뿐 아니라 시험 전 기간에 걸친 자돈의 일당중체량 및 일당사료섭취량은 처리 평균간 통계적인 유의차를 나타내지 않았으며, 다만 시험 전기간에 걸친 사료요구율에 있어서만 유의차가 인정되었으며, B와 D 처리구가 특히 우수한 것으로 나타났다 (p<0.05). 이유 1주동안 (Phase I)의 영양소 소화율은 DM과 CP를 제외하고는 처리 평균간 유의차가 인정되지 않았으며, A 처리구의 CP소화율은 다른 처리구에 비해 유의적으로 높았다 (P<0.05).그러나 B, C, D 그리고 E 처리구간에는 유의적인 차이가 보이지 않았다. 이유 14∼21일령 (Phase II)의 영양소 소화율은 처리평균간 유의차가 인정되지 않았으며, 이유 3주간에 걸친 건물, 질소 및 인의 배출량 역시 처리 평균간 유의차를 나타내지 않았다. 본 실험결과에서 나타난 바와 같이 14일령 이유자돈에 대한 탄수화물 공급원으로서의 lactose에 대한 sucrose의 대체는 자돈의 생산성 감소 및 영양소의 배출량 증가와 같은 불리함이 없이 이루어질 수 있음을 의미한다. This experiment was conducted to determine the optimum ratio of lactose to sucrose for nursery pigs weaned at 14 days of age. A total of 80 weaned pigs (BW 5.02±0.18 ㎏) were allotted into one of five treatments using a completely randomized block design. Treatments were 100:0 (A), 75:25 (B), 50:50 (C), 25:75 (D) and 0 :100 (E) in lactose : sucrose ratio. For the first week after weaning, no significant differences were found in average daily gain (ADG), average daily feed intake (ADFI) and feed conversion ratio (FCR, feed/gain). There were also no significant differences in ADG, ADFI and FCR among treatments during the second and third week after weaning. During overall experimental period, FCR was significantly influenced by dietary treatment, especially B and D treatments showed better FCR than other treatments (p<0.05). During the initial 7 day postweaning (Phase I), the nutrient digestibility was not influenced by the lactose: sucrose ratio except for dry matter (DM) and crude protein (CP). CP digestibility of diet A was significantly higher than those of other diets (p<0.05), but no significant.differences were found among diets B, C, D and E. During the second and third week postweaning (phase II), no significant differences were found in digestibilities of GE, DM, CA and P among treatments. There were no significant differences in nutrients excretion among treatments. These results indicate that sucrose can be well utilized by baby pigs as the source of carbohydrate after 15 days of age. It implies that lactose added in weaner diets could be partially replaced with sucrose.

급성 심근경색증 초기 진단에 latex 응집을 이용한 혈청 myoglobin 측정의 임상적 의의

박영배,서정돈,최윤식,이영우,오병희,손대원,임하진,김유우,박명희 대한내과학회 1987 대한내과학회지 Vol.32 No.2

We evaluated the diagnostic usefulness of latexagglutination test for elevated serum myoglobin as a screening test in the early phase of acute myocardial infarction and 21 patients with chest pain mimicking acute myocardial infarction were included in this study. Result was compared with serum myoglobin level measured by radioimmunoassay (RIA) in every case. The Following results were obtained: 1) When serum myoglobin levels measured by RIA below 85ng/㎖ were regarded as normal, this test showed sensitivity of 82%, specificity of 95%. 2) In latex-agglutionation test for elevated serum myoglobin, test results were interpreted as negative, weakly positive and positive. If we regard weakly positive tests as positive, sensitivity was 93% and specificity was 62%. In contrast, if we regard weakly positive tests as negative specificity rose to 100% while sensitivity reduced to 75%. 3) Agreement rate of both test was k=0.59. It is suggested that latex-agglutination test for elevated serum myoglobin is helpful in ruling out acute myocardial infarction when test result is negative, and that it can be used as a screening test in the early phase of acute myocardial infarction because of its rapidity and simplicity in performing the procedure.

인공판막 재대치험예에서의 판막실패의 양상

박영배,김유호,서정돈,최윤식,이영우,오병희,도문홍,최동주,전은석 대한내과학회 1987 대한내과학회지 Vol.32 No.3

In order to observe the aspects of prosthetic cardiac valve failure, we analyzed 26 cases of Redo operation among 1081 cases of valve replacemant performed from Jan. 1961. to July 1986. The results are as follows; 1) Crude Redo operation rate was 2.4%. 2) The most common cause or prosthetic cardiac valve failure was the primary tissue failure (73%) 8r the PVE was the 2nd (15.4%). 3) Mean valve implantation time was 47.7 months. Implantation time in the child group was shorter than in adult by 6.8 months, In the primary tissue failure group (19 cases) implantation time in the child was 42.8 months 8z in adult, 66.8 months. (P$lt;0.05) In conclusion, the durability of tissue valves was significantly decreased in the child age group because of increased propensity for calcification, so the preference of tissue valves especially in this age group should be reconsidered.

시료내 라이신 : 에너지 비율이 이유 자돈의 성장 및 영양소 소화율에 미치는 영향 DE RATIO ON THE GROWTH PERFORMANCE AND NUTRIENT DIGESTIBILITY IN WEANED PIGS

한인규,김진동,현충남,이지훈,강완병,현영 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.5

본 연구는 현대의 빠르게 성장하는 이유자돈에서 사료내 Lys : DE 비율이 이유자돈의 성장 및 영양소 소화율에 미치는 영향을 알아보기 위하여 실시되었다. 평균체중 5.70±0.14의 이유자돈 (Yorkshire×Landrace×Duroc) 100두를 공시하였고, 제 1기 (0∼14일) 동안, 두 수준의 에너지 (3,400과 3,600 ㎉ DE/㎏)와 두 수준의 Lys : DE 비율 (4.4와 4.9 g/Mcal), 제 2기 (15∼28일) 동안, 두 수준의 에너지 (3,300과 3,500 ㎉ DE/㎏)와 두 수준의 Lys : DE 비율 (4.4와 4.9 g/Mcal)이 되도록, 2×2 요인법으로 설계하였으며 4처리 5반복 반복당 5두의 이유자돈이 공시되었다. 시험 전기간 (0∼28일)동안, 일당중체량 (ADG)은 저 에너지-고 Lys : DE구가 저 에너지-저 Lys : DE구 보다 높았으며, 사료요구율 (FCR)은 고 에너지-고 Lys : DE구가 저 에너지-고 Lys : DE구를 제외한 나머지 처리구들 보다 낮은 경향을 보여 주었으나 유의한 수준은 아니였다. 사료내 Lys : DE 비율이 높아짐에 따라 ADG가 높아지는 경향을 보여 주었으나 유의하지는 않았다 (P>0.05). 그러나 FCR은 Lys : DE 비율이 높아짐에 따라 유의하게 개선되었으며 (P<0.05). 에너지 수준에 따른 차이는 관찰되지 않았다. 제 1기 동안 영양소 소화율은 사료내 에너지수준에 따라 영향받지 않았다. 건물소화율과 총에너지 소화율은 Lys : DE 비율이 증가함에 따라 유의하게 개선되었다 (P<005). 제 2기 동안 조지방을 제외한 영양소 소화율은 사료내 에너지 수준간에 따라 영향받지 않았다. 사료내 Lys : DE 비율에 따른 영양소 소화율에 있어 유의한 차이는 관찰되지 않았다. 제 1기 동안 필수 및 비필수 아미노산 소화율에 있어서는, 처리에 따른 유의한 차이가 관찰되지 않았다. 그러나 제 2기 동안 총필수 아미노산과 총 아미노산 소화율이 사료내 Lys : DE 비율이 증가함에 따라 유의하게 개선되었다 (P<0.05). 본 실험결과는 이유자돈이 4.4 g Iysine/Mcal DE 수준보다 4.9 g Iysine/Mcal DE 수준의 사료를 효과적으로 이용할 수 있음을 제시해 주었다. This study was carried out to evaluate the effect of lysine:energy ratio (Lys : DE) on growth performance and nutrient digestibility of weaned pigs. A total of 100 pigs (Yorkshire × Landrace × Duroc) averaging 5.7±0.14 ㎏ of initial body weight were employed. Two levels of dietary energy (3,400 and 3,600 ㎉ DE/㎏) with two levels of Lys : DE ratio (4.4 and 4.9 g/Mcal) for phase I period (0 to 14 d) and two levels of energy (3,300 and 3,500 ㎉ DE/㎏) with two levels of Lys : DE ratio (4.4 and 4.9 g/Mca1) for phase II period (15 to 28 d) were involved in a two × two factorial arrangement, respectively. Each treatment had five replicates with five pigs per replicate. During phase I period (0 to 14 d), no difference between groups in ADFI, and feed conversion rate (FCR) was significant. However, FCR was significantly improved with increased Lys : DE ratio (P<0.05). During phase II period (15 to 28 d), ADG, ADFI and FCR were not significantly (P<0.05) different among groups. There was no interaction between dietary energy concentration and Lys : DE ratio in growth performances of weaned pigs. FCR, however, was improved with increased energy level and Lys : DE ratio (P<0.05). During the overall period (0 to 28 d), there was no interaction between dietary energy concentration and Lys : DE ratio in growth performances of weaned pigs. However, there was a tendency for higher ADG with higher Lys : DE ratio. FCR was significantly improved with increased Lys : DE ratio (P<0.05), but was not affected by dietary energy concentration. During phase I period (0 to 14 d), no differences in nutrients digestibilities were observed between dietary energy levels. Between dietary Lys : DE ratios, dry matter (DM) and gross energy (GE) digestibilities were significantly (P<0.05) improved with higher Lys : DE ratio. During phase II period (15 to 28 d), no differences in nutrients digestibilities except energy levels. Between dietary Lys : DE ratios, no significant differences in nutrients digestibilities was observed. In regard to amino acids digestibilities, during phase I period (0 to 14 d), average values of essential amino acids (EAA), non-essential amino acids (NEAA) and total amino acids digestibilities were not significantly influenced by dietary energy levels and Lys : DE ratios. During phase II period ( 15 to 28 d), pigs fed high Lys : DE ratio diets showed significantly (P<0.05) higher total EAA and total amino acids digestibilities. The digestibilities of threonine, methionine, phenylalnine and serine were significantly improved as the dietary Lys : DE ratio increased. In conclusion, the results of the current experiment indicate that fast-growing weaned pigs might be able to use more effectively diets contatining 4.9 g lysine/Mcal DE compared to diets containing 4.4 g lysine/Mcal DE.

한국에서의 Human T-Cell Leukemia Virus Type-1(HTLV-1)에 대한 혈청학적 및 역학에 관한 연구

이영열,이성열,김은실,이홍복,김병국,이문호,박선양,김노경,서철원,규경채,최강원,조한익,고월청,야마구찌이찌세이 대한내과학회 1986 대한내과학회지 Vol.31 No.2

Type-C retrovirus, human T-cell leukemia virus type-l(HTLV-1), has been shown to be associated etiologically with adult T-cell leukemia, which is an endemic disease in southwestern parts of Japan. We examined the seroepidemiological characteristics of antibody to adult T-cell leukemia virus associated antigen (anti-ATLA-antibody) by the indirect immunofluorescent assay and ELISA from the healthy individuals and various diseased patients in the Republic of Korea, a country adjacent to Japan in which HTLV-1 is endemic. The results were as follows. 24 out of 9,603 individuals(0.25%) were seropiositive. The positve rate was 0.17% in males and 0.36% in females, the sex difference was female predominent relatively. HTLV-1 carriers were found 16 individuals in Seoul, 5 in Kyonggi area, 1 in Chungnam and Jonbuk, respectively, but found only 1 individual in Busan city and Jaejoo area close to southwestern parts of Japan. Positive rate to anti-ATLA-antibody seemed to be high in older age, especially at the 50s(0. 4Yo). In conclusion the prevalence rate of anti-ATLA- antibody seemed to be very low in the Republic of Korea adjacent to Japan in which HTLV-1 is endemic and no patient with adult T-cell leukemia has been found as yet. Also we noted that the Republic of Korea is not an endemic area to HTLV-1.

축산에서 탄수화물 복합체의 응용

최윤재,조광근,윤연화,김성찬,김재영,손광수,박영우 한국낙농학회 1999 韓國酪農學會誌 Vol.21 No.4