성인병에 대한 한방치료법(증치의학과 사상의학)에 관한 연구 : 고혈압에 대한 한방치료법(중치의학과 사상의학)에 관한 연구

박동일,김영균,안창범,이인선,김종원,권정남,장경전,이인선,이성근,장용우,신영민 동의대학교 한의학연구소 1999 동의한의연구 Vol.3 No.-

We had a result of the treatment as below when is devided Korean medicine Tx.. Western medical Tx., Cooperative Tx.. 1) At the improvement of BP control, an average in Korean medicine Tx. (from 170㎜Hg/100㎜Hg to 150㎜Hg/90㎜Hg), an average in Western medical Tr. (from 170㎜Hg/100㎜Hg to 130㎜Hg/80㎜Hg), an average in Cooperative Tx.(from 180㎜Hg/110㎜Hg to 130㎜Hg/90㎜Hg), generally all pars had improvements of BP control. But it is not significant of each case. 2) At the improvement of symptoms by the apologetics, Cooperative Tx. is profitable in cases of 'GanHwa',' DamEum', 'EumYangYangHer', 'EumHer'. Korean medicine Tx. is superior in case of 'GiChe'. 3) At the improvement of symptoms by a questionnaire, Korean medical Tx., Western medical Tx., Cooperative Tx. groups had improvements, but each practice group didn't have specific significance. Only it was somewhat profitable to Korean medical Tx. in the 210㎜Hg/110㎜Hg, Western medical Tx. in the 180㎜Hg/110㎜Hg, Cooperative Tx, in the 170㎜Hg/90㎜ Hg. 4) There are the apparent improvements in patients whose BP are over 200㎜Hg of Korean medical Tx. group, whose BP are over 190㎜Hg of Western medical Tx. group and whose BP are over 170㎜Mg of Cooperative Tx. group. There are the improvement of diastolic BP in 110㎜Mg(Korean medical Tx., Western medical Tx.) and 90㎜Hg(Cooperative Tx.). 5) At the improvement of Pulse pressure, generally Pulse pressure are decreased. There are similar improvements in all of Korean medical Tx., Western medical Tx., and Cooperative Tx.. 6) At the Symptomatic approvement according to ages, Korean medical Tx., Cooperative Tx. are somewhat good for his twentieth, and Western medical Tx. is somewhat good for his forties. 7) the correlation of Obesity-grade and BP, as Obesity-grade is higher as BP is higher, but there are no similarity in the improvement. 8) At the EAV improvements, as examination into correlation with the point of 1~3th, we could get results as below. There are high improvements of DRHTM, DRALM, DLLYM, DLLIM in Cooperative Tx. There are high improvements of DRPASI, DLLARI in the Korean medical Tx. group. There are high improvements of DRFADM in Western medical Tx. group.

生體血의 保存環境과 腐敗産物에 依한 血中알콜濃度變化에 關한 硏究

張成吉,金英雲,柳在薰,吳世珍,權五星,朴世延 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

이산화된 탐색공간에서 다구찌 방법을 이용한 구조 최적설계에 관한 연구

장성현,정우영,정용민,권봉철,최영휴 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

Nowadays, there are several design problem having discrete variables in the industrial fields. The researchers are using the optimization method, such as genetic algorithm (GA), simulated annealing (SA), design of experiment (DOE) and taguchi method (TM), to solve it's design problem. Moreover, people want to decrease the computational cost and time. Therefore, in this paper, we proposed the iterative optimization algorithm which repetitively searched a local region to find best solution in discrete searching space using TM. The optimal solution in each local region is obtained by S/N ratio for the evaluation function that consists of the objective function and penalty function. Also, we have applied our algorithm to 3-bar, 10-bar, and 25-bar truss optimization problem.

편평 세포암, 광선 각화증 및 Bowen병에서 p53과 Ki-67의 발현 양상

장영우,양승하,김의한 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : The function of p53 protein was known to regulate damaged cell proliferation in S phase, so damaged cell proliferation was not occurred by apoptosis. Ki-67 nuclear antigen has been used as a marker to define growth fraction in both benign and malignant tumors. The Ki-67 nuclear antigen was expressed throughout the cell cycle except G0 and early G1 phase. The role of p53 and Ki-67 in oncogenesis, tumor progression and prognosis were important. The authors analyzed immunohistochemical expression of p53 and Ki-67 in squamous cell carcinoma, actinic keratosis and Bowen's disease. Method: Seventeen cases of squamous cell carcinoma, fifteen cases of actinic keratosi and seven cases of Bowen's disease were immunohistochemically stained with p53 and Ki-67 monoclonal antibodies. Results: 1. p53 protein were expressed mainly in basal layer in well differentiated squamous cell carcinoma and diffusely expressed in poorly differentiated squamous cell carcinoma. In actinic keratosis, the expression pattern of p53 was similar to well differentiated squamous cell carcinoma, but the intensity was lower. 2. In Bowen's disease, the p53 protein was more diffusely and strongly expressed than squamous cell carcinoma. 3. The ki-67 labelling index in squamous cell carcinoma was below 20% regardless of differentiation. In actinic keratosis, the labelling index was lower. 4. The Ki-67 labelling index in Bowen's disease was higher than squamous cell carcinoma and weakly expressed in basal layer, especially adjoining dermis. 5. In mitotic cells, the p53 protein was not expressed, but Ki-67 nuclear antige was strongly expressed. Above results suggested that Bowen's disease is almostly composed of immature cell while squamous cell carcinoma was composed of the mature and immature cells. In spite of higher labelling index in Bowen's disease, the growth rate is really faster in squamous cell carcinoma. The authors suggested the reason that the number of the mitotic cells in Bowen's disease were fewer than that of squamous cell carcinoma.

아메바성 대장염과 연관된 Henoch-Scho¨nlein Purpura 1예

장재현,원경준,이준,변유미,이재광,김영훈,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Henoch-SchonIein purpura is a common form of vasculitis primarily involving the skin, the gastrointestinal tract, the joints, the kidneys, and the nervous system. The etiological investigations are essential, because triggering factors are found in approximately half the patients such as viral, bacterial and parasitic infections, drugs, toxins, systemic diseases and cancer. But it's the correlation between Henoch-SchonIein purpura and Entamoeba histolytica has been rarely reported. We report a 29-years-old woman with Henoch-SchoIein purpura complicated by the lower gastrointestinal bleeding caused by the amoebic colitis. She complained of cramping abdominal pain, lower extremity purpura and hematochezia. Cysts and trophozoites of Entamoeba histolytica were detected in her stool. Skin biopsy demonstrated the leukocytoclastic vasculitis. She was administered metronidazole 1,500㎎ a day for the treatment of amebic colitis. Her hematochezia was improved, but the abdominal pain and purpura were not. The subsequent corticosteroid therapy improved her symptoms.

데스크탑 밀링기의 경량 ·고강성화 구조 최적설계

장성현,정우영,홍정표,최영휴 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

This paper describes a case study on the structural design optimization of a desktop milling machine for microfactory. Actually, the structural dynamics analysis is necessary to machine tool design and development to secure high precision machining performance. In the preliminary design stage, one of design alternatives for a desktop milling machine was chosen according to F.E.M structural analysis. It had relatively stronger than others but unfortunately had not enough structural rigidity. After all, we carried out the static design optimization for the chosen design alternative to decrease compliance. The static design optimization problem, in this study, is to find out thickness of structural members which minimize the weight and the static compliance under several constraints. The optimization results showed a great reduction in the compliances, moreover, vibration amplitudes at the spindle nose of this machine tool was also reduced greatly. We successfully designed the machine structure having less static compliance than the critical value.

림프절 질환들에서 병변에 따른 수지상 세포의 변화

장영우,김대중,양승하,김의한 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

The reaction patterns of the dendritic cells in lymph node lesions was as follows; 1. The number of the dendritic cells in the nonspecific lymphadenitis showed no significant decrease, so the immunologic reaction in the lymph nodes substained. 2. The number of the dendritic cells in tuberculous lymphadenitis showed significant decrease in case of the tubercles present in the lymph node than in case of no tubercle present. 3. The dendritic cells in lymph nodes of gastric adenocarcinoma were entirely disappeared regardless of metastasis. 4. The dendritic cells in lymph node of infiltrating ductal carcinoma were observed significantly regardless of metastasis. Above results suggested that the no expression of dentritic cells appeared to be the result of loss of function than disappearance. The loss of function of dendritic cells meaned that the easy infiltration of agents due to lack of immune reaction Because the immune reaction of lymph node in infiltrating ductal carcinoma was sustained while the immune reaction of lymph node in gastric adenocarcinoma was significantly reduced, the prognosis of infiltrating ductal carcinoma was better than gastric adenocarcinoma. But more research is necessary about the other prognostic factors.

CDMA 시스템의 시뮬레이션 프로그램 구현 및 이를 이용한 전력 제어 분석

장우영,장태정 강원대학교 정보통신연구소 2002 정보통신논문지 Vol.6 No.-

Recently, CDMA system has been widely used in wireless communication systems. Since all the signal shares a frequency band and is discriminated from each other by code, the reverse link power control is very important to improve the communication quality and to increase the system capacity. In this paper, a program was constructed by using Matlab to simulate and analyze the power control in CDMA systems based SIR(Signal to Interference Ratio). Through simulations by using the program, we observed some known characteristics of the power control and the capacity of a CDMA system. We also found that for a new active user, one step jump command to average received power of current active users in the cell as the first target power command in the reverse link of the new user, instead of 1 dB step size as given in IS-95(a), can greatly reduce the stabilizing time in power control.

진행성 위암과 동반된 후복막 섬유화증 7예의 임상적 고찰

장재영,천영국,최우봉,김진오,조주영,이준성,이문성,심찬섭 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background/Aims: Retroperitoneal fibrosis is a fibrosing disease process which frequently develops ureteral obstruction. Malignant retroperitoneal fibrosis has been reported that various types of cancer including cancer of the breast, stomach, prostate, lung, cervix, uteri, colon, pancreas, ovary, and even Hodgkin's disease. While the pathogenesis remains obscure, small foci of metastatic neoplasm in the retroperitoneal space can elicit a desmoplastic reaction in secondary form to malignancy. Methods: Recently we experienced 7 cases of retroperitoneal fibrosis with advanced gastric cancer. So, we report 7 cases of retroperitoneal fibrosis with clinical and radiologic characteristics. Results: The most common signs and symptoms were related irreversible renal dysfunction. The urologic finding noted medial deviation of the involved ureters and hydronephrosis Conclusions: Clinical manifestations are abdominal pain, back pain, hydronephrosis, and uremia. When sudden back pain and hydronephrosis develop in advanced malignancy, physicians should be considerd for retroperitoneal fibrosis.

궤환선형화와 LMI기법을 통한 PMSM의 H₂/H∞제어에 관한 연구

장우영,박승규 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-

The purpose fo this paper is to obtain the mixed H₂/H∞controller for the PMSM which is nonlinear system. The mixed H₂/H∞control problem of the nonlinear system requires the coupled Hamitonian-Jacobi-Isaacs equations. And it is not easy to obtain the solutions. So we change this problem to the LMI(Linear Matrix Inequality) condition by using feedback linearization.