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      • KCI등재

        The Gender-Sensitive Social Risk Factors for Internet Addiction in College Undergraduate Students

        Xia Lin,Jing-yan Gu,Wan-jun Guo,Ya-jing Meng,Hui-yao Wang,Xiao-jing Li,Wei Deng,Lian-sheng Zhao,Xiao-hong Ma,Ming-li Li,Ting Chen,S,K,Cheng,Tao Li 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.7

        Objective The current study aims to explore precipitating and social risk factors for internet addiction (IA) in university undergraduate students, and to provide evidence for interventions and the early prevention of IA in different genders. Methods Four thousand eight hundred and fifty-eight college sophomores completed an online survey on their internet use-related behaviours and social risk factors. Results We found that more male (8.3%) than female students (5.4%) had moderate and severe IA. The main online activity in the moderate and severe IA groups was online gaming in males and online streaming in females. Roommates engaging in similar internetbased entertainment was a risk factor of IA only for males, while not being in a romantic relationship was a risk factor of IA for females only. Infatuation with the internet before college and adjustment problems for college life were shared risk factors for both genders in the mild and moderate IA groups. Conclusion IA was a common phenomenon in college students with shared and unique precipitating and social risk factors in males and females. The gender-sensitive risk factors for IA warranted earlier and individualized intervention and prevention strategies for IA in this population.

      • KCI등재

        Effects of a Compound Extract from Agrimonia pilosa Ledeb, Grifola umbellata (pers.) Pilat, and Gambogia on Human Gastric Carcinoma MGC-803 Cells

        Li Zhao,Xiao-Nan Zhang,Hong-Yan Gu,Jia Wang,Lei Tao,Rong Mu,Qing-Long Guo 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.1

        Three traditional Chinese medicines, Agrimonia pilosa Ledeb, Grifola umbellata (pers.) Pilat, and Gambogia, are combined to form a compound extract, AGC. In this study, the in vitro and in vivo inhibitory effects of AGC on human gastric carcinoma MGC-803 cells were demonstrated, and the molecular mechanisms underlying these effects are investigated. Our results indicate that AGC inhibited MGC-803 cell growth in a dose-dependent manner as measured by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, with an IC?? of about 6.045±0.69 ㎍/㎖. In vivo, AGC inhibited growth of human gastric carcinoma in xenograft tumors in nude mice, and the inhibitory rate reached 55.2% at 300 ㎎/㎏. The pro-apoptotic activity of AGC was attributed to its ability to decrease the expression of Bcl-2 and Pro-caspase3 and increase the expression of Bax. These results demonstrate that AGC can effectively induce programmed cell death and may be a promising anti-tumor drug in human gastric carcinoma.

      • SCIEKCI등재

        A Study on Cutting and Tribology Performances of TiN and TiAlN Coated Tools

        Li, Hua-Ying,He, Hui-Bo,Han, Wen-Qiang,Yang, Jun,Gu, Tao,Li, Yuan-ming,Lyu, Sung-Ki Korean Society for Precision Engineering 2015 International Journal of Precision Engineering and Vol.16 No.4

        TiN and TiAlN coatings were deposited on the surface of AISI 5140 steel and cemented carbide YT15 by magnetron sputtering technique (MSP). The reciprocating sliding tests of TiN and TiAIN coatings on the surface of AISI 5140 steel were performed to investigate the friction coefficients of coatings affected by various normal loads with friction pair of 304 stainless steel balls. Dry machining tests on AISI 5140 hardened steel were carried out with the TiN and TiAlN coated tools on a CA6140A lathe. The effects of cutting speed on cutting forces and surface roughness of TiN and TiAlN coated tools were obtained and analyzed to assess the cutting performance of coated tools. The microcosmic micrographs of wear areas of coated tools were observed and investigated by scanning electron microscope and energy dispersive spectrum. The results show that the friction coefficients of TiN coatings are lower than that of TiAlN coatings. The cutting force of TiAlN coated tool decreases and flank wear resistance enhances in comparison with TiN coated tool. The wear form and mechanisms of TiN coated tool are mainly crater wear on the rake face and adhesive wear and abrasive wear on the flank face. The wear form and mechanisms of TiAlN coated tool are mainly adhesive wear, the breakage of cutting edge and the damage of tip, accompanied with diffusion and oxidation wear.

      • KCI등재

        Behavior of Steel-concrete Composite Cantilever Beams with Web Openings under Negative Moment

        Tao Chen,Xianglin Gu,Hua Li 한국강구조학회 2011 International Journal of Steel Structures Vol.11 No.1

        The effect of web openings on the mechanical behavior of composite beams under negative moment was studied through monotonically loading tests. Nonlinear finite element method based analysis was also conducted for cantilever composite beams. The test and the finite element analysis results indicated that the initial cracking loads of composite beams with web opening are lower than that without web opening. The first crack initiated from the concrete slab on the top of the opening. The beams with web opening failed due to shear failure of concrete slab upon the opening. It was also found that the load carrying capacity of beam decreases with the increase of the moment-to-shear ratio at the central line of the opening and the mechanical behavior of beam can be improved significantly by applying stiffening steel plates around the opening. To quantify the reduction of load carrying capacity, a method for calculating the load carrying capacity of beams with web openings under negative moment was derived with consideration of the interaction between moment and shear. Good consistency was obtained between the proposed method, the finite element method and the test results.

      • Research on Health Crowdfunding: A Literature Review

        Gu, Rui,Li, Jing,Xue, Tao 한국지능정보시스템학회 2022 한국지능정보시스템학회 학술대회논문집 Vol.2022 No.6

        Health crowdfunding has become an important supplement to the health fundraising system and has attracted increasing attention from both researchers and practitioners. However, few efforts have been devoted to integrating the existing finding. This paper aimed to fill this gap. We conducted a systematic review of relevant literature and accordingly classified health crowdfunding into three types: health research crowdfunding, health innovation crowdfunding, and health expenses crowdfunding. Based on this classification. we reviewed the existing findings and discussed future research directions. This paper serves as a foundation for future research to conduct in-depth investigation and advances our understanding of health crowdfunding.

      • KCI등재

        Terahertz Computed Tomorgraphy with a Quantum Cascade Laser and a Quantum-well Photodetector

        Tao Zhou,Li Gu,Zhi-Yong Tan,Jun Cheng Cao 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.2

        In this letter, a terahertz (THz) tomography system based on a quantum cascade laser (QCL)and a quantum-well photodetector (QWP) is demonstrated. The QCL provides a relatively high power (a few microwatts) in a continuous-wave mode at 3.9 THz as a light source, and the QWP provides a narrow response range from 3 to 7 THz with a calibrated peak response of 0.5 A/W under background-limited performance. We employ the widely-used filtered back projection (FBP)and algebraic reconstruction algorithms for terahertz tomography technology. The reconstructed cross-sectional image of a sample has successfully revealed the internal and the external structures with a resolution of around 1.5 mm. This experiment demonstrates that the terahertz QCL and the photodetector are potentially useful for terahertz tomography applications.

      • SCIESCOPUSKCI등재

        Temporal expression profiling of long noncoding RNA and mRNA in the peripheral blood during porcine development

        Gu, Yiren,Zhou, Rui,Jin, Long,Tao, Xuan,Zhong, Zhijun,Yang, Xuemei,Liang, Yan,Yang, Yuekui,Wang, Yan,Chen, Xiaohui,Gong, Jianjun,He, Zhiping,Li, Mingzhou,Lv, Xuebin Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.5

        Objective: We investigated the temporal expression profiles of long noncoding RNA (lncRNA) and mRNA in the peripheral blood of pigs during development and identified the lncRNAs that are related to the blood-based immune system. Methods: Peripheral blood samples were obtained from the pigs at 0, 7, 28, and 180 days and 2 years of age. RNA sequencing was performed to survey the lncRNA and mRNA transcriptomes in the samples. Short time-series expression miner (STEM) was used to show temporal expression patterns in the mRNAs and lncRNAs. Gene ontology and Kyoto encyclopedia of genes and genomes analyses were performed to assess the genes' biological relevance. To predict the functions of the identified lncRNAs, we extracted mRNAs that were nearby loci and highly correlated with the lncRNAs. Results: In total of 5,946 lncRNA and 12,354 mRNA transcripts were identified among the samples. STEM showed that most lncRNAs and mRNAs had similar temporal expression patterns during development, indicating the expressional correlation and functional relatedness between them. The five stages were divided into two classes: the suckling period and the late developmental stage. Most genes were expressed at low level during the suckling period, but at higher level during the late stages. Expression of several T-cell-related genes increased continuously during the suckling period, indicating that these genes are crucial for establishing the adaptive immune system in piglets at this stage. Notably, lncRNA TCONS-00086451 may promote blood-based immune system development by upregulating nuclear factor of activated T-cells cytoplasmic 2 expression. Conclusion: This study provides a catalog of porcine peripheral blood-related lncRNAs and mRNAs and reveals the characteristics and temporal expression profiles of these lncRNAs and mRNAs during peripheral blood development from the newborn to adult stages in pigs.

      • KCI등재

        Mathematical Model Relating Dynamic Dewatering Process of Fresh Mortar and Its Composition

        Tao Ji,Xiaoying Zhang,Xiong Zhang,Yong-juan Zhang,Caiyong Gu,Weihua Li 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.2

        The composition and properties of raw materials have significant influences on water retention capacity of mortar, but the basic origin remains unclear. To clarify the movement of water inside mortar and the mechanism of water retention, the dynamic dewatering experiment was designed and the mathematical model describing the dewatering process of mortar was set up in this work. The model proved to be effective according to the results from dynamic dewatering experiment. The study demonstrated that capillary gradual contraction model is suitable for describing early dewatering process of fresh mortar and the parameters in the dewatering equation are relevant to the properties of raw materials, which certify that the model is of physical significance. Moreover, influencing factors such as water properties and binding materials properties were obtained and their relationship with water retention of mortar were discussed theoretically based on capillary gradual contraction model.

      • KCI등재

        Novel Method to Improve the Microstructure and Mechanical Properties of 45 Steel

        Tao Gu,Shuaixin Zhang,Yuhong Zhao,Yurong Yang,Huafeng Liu,Li Wu,Jianhua Liu,Hua Hou 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.4

        Aiming at the problems of poor hardenability and low mechanical strength of 45 steel after quenching and tempering atnormal pressure, 45 steel was quenched and tempered under high pressure. The microstructure of 45 steel after high pressurequenching and tempering was analyzed by optical microscope, scanning electron microscope and transmission electronmicroscope, its hardness and compressive strength were tested by hardness tester and electronic universal testing machine,and compared with samples treated by the same process under atmospheric pressure. The results show that uniform andcompact tempered sorbite can be obtained after high pressure quenching and tempering of 45 steel, and the precipitatedgranular carbides are finely dispersed, thus improving the mechanical properties of 45 steel. Under a pressure of 3 GPa,quenching at 900 °C for 15 min and 550 °C for 60 min tempering, the hardness and compressive yield strength of 45 steelwere 36.3 HRC and 971 MPa, respectively, which were respectively 25.17% and 20.77% higher than the corresponding valuesobtained with the same process under atmospheric pressure quenching and tempering. This work provides a new method toeffectively improve the mechanical properties of 45 steel.

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