흉수부에 발생한 희돌기 교세포종(Oligodendroglioma) 1예 : 증례보고 Case Report

고현송,송시헌,김관태,김성호,김윤 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.5

Primary oligodendroglioma of the spinal cord is a very rare tumor. On searching through the literature from 1931. we could find only about 46 cases, and tumor is almost absent in Korea on the review of the literature. The authors present a case of 8-year-old female patient with the symptoms of paraparesis, urination difficulty. diffuse back pain and hypesthesia in both lower extremities. Spine MRI revealed the mass at the level of T(3)-T-(12), with combined nature of cystic and solid portion. Decompressive laminectomy and partial mass removal was performed, and then adjunctive radiotherapy and chemotherapy was done. The patient was improved after operation with radiotherapy and chemotherapy. so he walks alone and has no voiding difficulty at present (postoperative about 20months),

경찰공무원의 건강체력 실태

노성규,손호중,고성은,엄경일,권호준 江原大學校附設體育科學硏究所 2003 江原大學校附設體育科學硏究所論文集 Vol.- No.26

The purpose of this study is to suggest basic data to make out the program about the health and promotion of physical fitness. So, we measured the status of the present police officers physical fitness through measuring their height, weight, %body fat, and healthy physical fitness and through comparing it with popular physical fitness survey data in an age. The conclusion that compared and analyzed the measuring result of the height, weight, and the element of healthy physical fitness of 143 police officers in G province is following First, Their height, weight, board jumping and VO2max is seemed to be high as compared with the standard. Second, %Body fat is closely similar with the standard. Third, The flexibility and sit-up is seemed to standard below By this time, it is true that the study of the superiority players evaluation of physical fitness is developing in our country. But, the study of the physical fitness evaluation about non-player, that is general person has been neglected in korea. So, it is not very enough the study and developing program for the improving the general person's physical fitness. Therefore, It should make the spacial study of the various physical fitness of korean in an occupation, a sex and age. And then, the special exercise program that can satisfy the various needs of today 'men is needed. Also, it should make the vertical study for the improvement of physical strength in vocational classification. Also, the government and office should invest institutional effort to help the police officer' health and welfare. Police officers also have to learn themselves the efficient and continuous exercise habit to be happy with health in considering their own physical condition. And then, the prescription of the exercise program about the result must come with.

나트륨系 化學添加劑가 注入된 粘性土의 壓縮强度에 關한 硏究

趙誠正,高光虎 충북대학교 농업과학기술연구소 1993 農業科學硏究 Vol.10 No.2

This study was conducted to investigate the effect of chemicals on the characteristics of com-paction and unconfined compressive strength in brown and black clay soil chemicals. Unconfined compressive strength and compaction tests were performed by adding of sodium sulfite, sodium chloride, sodium carbonate, calcium chloride, magnesium oxide, lime and plaster to the amount of 0, 2, 4, 6, 8% by weight of dry soil to two kinds of brown and black clays. After the specimens of soil chemicals were molded, they were cured during 0, 7 and 28 days in the curing chamber having more than 95 percent of relative humidity and 23±1℃ of temperature. The results obtained were as follows ; 1.The relationship between the maximum dry density and the optimum moisture content of soil chemical mixture showed high correlation and the regression equations were as follows : 2.In the brown and black clay soil chemical mixture, with the addition of more sodium chloride, calcium chloride, sodium carbonate and sodium sulfate, the optimum moisture contents of soil chemical mixtures were decreased, the maximum dry density increased, but with the addition of more magnesium oxide· and lime, the values of the optimum moisture content and the maximum dry density were opposite. In the brown clay soil chemical mixture, the more the amount of plaster contained, the more was the value of optimum moisture content of soil chemical mixture and the less was the maximum dry density, but in the black clay soil chemical mixture there was not a clear tendency. 3.In the brown clay the unconfined compressive strength of soil chemical mixture adding of sodium chloride, sodium carbonate, calcium chloride, plaster and sodium sulfite was decreased with the addition of more chemicals, but in the case of magnesium oxide and lime, on the contrary unconfined compressive strength was increased. In the black clay, with the addition of more chemicals, the unconfined compressive strength of soil chemical mixture adding of calcium chloride and sodium carbonate was decreased, but soil chemical mixture adding of lime and magnesium oxide was increased conversely. The unconfined compressive strength of soil chemical mixture adding plaster was the greatest at the 4 percent of plaster content, those of soil chemical mixtures adding sodium chloride and sodium sulfite were not definite, but were decreased generally. 4.In the brown and black clays, unconfined compressive strength of soil chemical mixture adding sodium chloride, sodium carbonate, sodium sulfite, plaster and calcium chloride was decreased in accordance with the longer curing period, but in case of lime and magnesium oxide was increased on the contrary. 5.In the soil chemical mixture mixed with 8 percent of chemical content to brown clay soil, on the basis of 28-day strength, the effect of chemicals was arranged in the order of lime, magnesium oxide, plaster, sodium carbonate, sodium sulfite, calcium chloride and sodium chloride, in the black clay soil, the order of effect was lime, magnesium oxide, plaster, sodium sulfite, calcium chloride, sodium carbonate and sodium chloride.

Crawford Ⅲ형과 Ⅳ형 흉복부 대동맥류 4예 보고

문성민,손민수,이길연,이상목,고석환,홍성화,윤충,오수명,박호철 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2

KCCH cyclotron neutron 및 60Co r-ray에 의한 인체 말초혈액 임파구의 염색체 이상측정

김성호,김태환,정인용,조철구,고경환,류성렬 대한방사선 방어학회 1992 방사선방어학회지 Vol.17 No.1

KCCH cyclotron neutron(30cCy/min) 및 ??Co γ-ray(210cGy/min)를 시험관내의 정상 인체 말초혈액임파구에 조사하여 염색체이상(dicentric 및 centric ring)을 관찰하고 이의 선량-반응관계식을 linear model(Y=K₁D+a), power-law model(Y=K₂Dⁿ), quadratic model(Y=K₃D²) 및 linear-quadratic model(Y=αD+βD²)을 사용하여 구하고 이들 model중 염색체이상의 측정치와 가장 일치하는 관계식을 근거로 하여 γ -ray에 대한 neutron의 relative biological effectiveness(RBE)를 산출하였다. 염색체 이상(dicentric plus centric ring)의 발생분포는 γ-ray의 경우 linear model(P=0.067)을 제외한 power-law model[Y=(5.81±1.96)×10??, P=0.931], quadratic model [Y=(3.91±0.09)×10?D², P=0.972] 및 linear-quadratic model [Y=(6.55±6.83)×10?D+(3.72±0.22)×10?D², P=0.922]에 적합하였다. Neutron의 경우 linear model [Y=(6.12±0.17)×10?³ D-022, P=0.987]에 가장 일치하였고 quadratic model (P<0.005)을 제외한 power-law model[Y=(2.43±0.70)×10?³D+(1.21±0.39)×10?D², P=0.415]에 비교적 적합하였다. 세포당 0.1-1.5개의 염색체이상을 나타내는 neutron의 γ-ray에 대한 RBE는 2.714±0.408이었다. The frequencies of KCCH cyclotron neutron(30cCy/min) or ??Co γ-ray(210cGy/min)-induced asymmetrical interchanges(dicentrics and centric ring) and acentric fragment(deletion) at several doses were measured in the normal human peripheral blood lymphocytes. Chromosome aberrations were scored at the first nitosis after stimulation with phytohemagglutinin. The neutron and γ-ray data were analysed on liner, power-law, quadratic and linear-quadratic model. When the dicentrics and centric rings of γ-ray datas were pooled and fitted to these model, good fits were obtained to power-law [Y=(5.81±1.96)×10??, P=0.931], quadratic [Y=(3.91±0.09)×10?D², P=0.972] 및 linear-quadratic model [Y=(6.55±6.83)×10?D+(3.72±0.22)×10?D², P=0.922] except for linear model(P=0.067). As in the case of neutron data, the best fits was obtained to the linear model [Y=(6.12±0.17)×10?³ D-022, P=0.987] and good fits were obtained to power-law[Y=(5.36±3.02)×10?⁴D??, P=0.601] and linear-quadratic model [Y=(2.43±0.70)×10?³D+(1.21±0.39)×10?D², P=0.415], except for quadratic model (P<0.005). The relative biological effectiveness(RBE) of neutron compared with γ-ray was estimated by best fitting model. In the asymmetrical interchanges range between 0.1 and 1.5 per cell, the REE was found to be 2.714±0.408.

PTFE 이식편을 이용한 대퇴동맥과 슬관절이하 동맥 우회로술의 결과 분석

문성민,손민수,이길연,이상목,고석환,홍성화,윤충,오수명,박호철 대한혈관외과학회 2004 Vascular Specialist International Vol.20 No.1

육안적 혈뇨로 내원한 환자에서 발견된 방광 유전분증 : 증례보고

김은진;성 현;홍수민;정성연;박경식;손형래;박일권;구호석;고행일 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-

Amyloidosis is a disease resulting in deposition of amyloid in the body. The disease can be either primary or secondary. The amyloidosis of urinary bladder is more usually affected by primary amyloidosis and also very rare. The patient with primary amyloidosis of the bladder usually presents with gross hematuria. The amyloidosis resembles bladder cancer in cystoscopy. It can be confirmed by biopsy. The treatment consists of medication (e.g., steroid, antitumor agent, cholchicine, DMSO) and/or transurethral resection. The standard treatment is mephalan and prednisolone. A 49-year-old man complained of recently developed gross hematuria without abdominal pain. We examined urinary bladder cystoscope for gross hematuria. It revealed small bulging mass on trigone are a of bladder. Therefore we did bladder biopsy. Finally, it revealed bladder amyloidosis. The patient was improved by medication (mephalan 2mg and prednisolone 1 mg/kg po daily). We report an unusual case of amyloidosis involving bladder.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

혈액투석 환자에서 대퇴신경범증으로 발현된 장골근 및 요근 농양 1예

이준상,강동구,신상열,윤재호,조영일,고성은,유영범,전혜정,진춘조,송종오 대한신장학회 2004 대한신장학회잡지 Vol.23 No.1

The Role of the PI3K Pathway in the Regeneration of the Damaged Brain by Neural Stem Cells after Cerebral Infarction

Koh, Seong-Ho,Lo, Eng H. 대한신경과학회 2015 Journal of Clinical Neurology Vol.11 No.4

<P>Neurologic deficits resulting from stroke remain largely intractable, which has prompted thousands of studies aimed at developing methods for treating these neurologic sequelae. Endogenous neurogenesis is also known to occur after brain damage, including that due to cerebral infarction. Focusing on this process may provide a solution for treating neurologic deficits caused by cerebral infarction. The phosphatidylinositol-3-kinase (PI3K) pathway is known to play important roles in cell survival, and many studies have focused on use of the PI3K pathway to treat brain injury after stroke. Furthermore, since the PI3K pathway may also play key roles in the physiology of neural stem cells (NSCs), eliciting the appropriate activation of the PI3K pathway in NSCs may help to improve the sequelae of cerebral infarction. This review describes the PI3K pathway, its roles in the brain and NSCs after cerebral infarction, and the therapeutic possibility of activating the pathway to improve neurologic deficits after cerebral infarction.</P>