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어린이 김치 표준화에 대한 연구(1) : 어린이 김치의 담금법 개발 Development of the Preparation of Kimchi for the Children
송영옥,전영수,권명자,빈성미,김은희,문정원,김명 부산대학교 가정대학 1995 家政大學硏究報告 Vol.21 No.-
The purpose of this study is reporting the results of first trial for the standardization of children's kimchi in terms of brining standardization, development for the recipe ad pannel test for the children's kimchi. In order to develop the standard recipe for children's kimchi, our research team have visited kimchi factories, temples and houses located in Pusan and Kyung-Sang Nam Do province. Three kinds of chinese cabbage kimchi (hamyang, haeundae, and jinrae kimchi named by region where we collected) which got the top three highest score in panel testing was selected. The original recipes of these kimchi were sightly modified to prepared the kimchi at laboratory. Among three of them, hamyang kimchi which contained dried anchovy power was selected as a model kimchi for development of the children's kimchi recipe. We find out that the optimal salt concentration of brined cabbage and kimchi for the children's kimchi (sliced style kimchi, approximately 2.5X3cm a piece) that showed the hightest pennel score were approximately 1.5% and 2.0%, respectively. The salt concentration of brined cabbage became 1.5, 1.43, and 1.60% after 60 min at 10% brining solution, 45 min at 12% and 30 min at 15%, respectively. The developed recipe used for the children's kimchi at our team is as follows. The major ingredients used for the preparation of kimchi is brined sliced chinese cabbage (salt concentration is 1.5%) 1kg galic 11g, ginger 5.0g, red pepper powder 20.0g, fermented anchovy juice 25.0g, fermented shrimp juice 5.0g dried anchovy and sea weed extracts 30.0g, anchovy power 2.4g glutinious rice gel 40.0g, starch syrup, 10.0g, and apple juice 22.5g. The total acceptability test of developed children's kimchi (test kimchi) was carried out with 84 of 6th grade student during lunch time at elementary school in Pusan where has a school lunch program. Sixty nine percent of student answered test kimchi is very good, 25% of them said it is fair, and only 6% of students answered they didn't like test kimchil. However, for the kimchi supplied from school at lunch, 52% students answered the kimchi is good, 26% of them said it is fair, and 22% of them said they don't like school supplied kimchi. This result tells us that the test kimchi is better than school supplied kimchi and the test kimchi can be developed further as a children's kimchi.
張明洙,宋浚泰 全北大學校 附設 都市및環境硏究所 1990 都市 및 環境硏究 Vol.5 No.-
The purpose of this study is to, through the research of the history of Chonju, find out the object of restoration among historic remains damaged artificially, preserve the characteristics of the areas in which historic remains existing right now are cellectively distributed and to re-organize their historic environment coupled with cultural individuality and peculiarity. The results of the study are summarized as follows; First, the East gate, the West gate, and the North gate except for the presently existing the South gate should be restored, and Sun Hwa Dang which was the center of Kwan-A in the old castle (old Chonju city) and other accessory buildings restored. Second, in order to solve these problems mentioned above, I propose that area of human activity, one of the elements for urban landscape, be organized.
RPL36 as a prognostic marker in hepatocellular carcinoma
Song, Myeong Jun,Jung, Chan Kwon,Park, Chung‐,Hwa,Hur, Wonhee,Choi, Jung Eun,Bae, Si Hyun,Choi, Jong Young,Choi, Sang Wook,Han, Nam Ik,Yoon, Seung Kew Blackwell Publishing Asia 2011 Pathology international Vol.61 No.11
<P>Ribosomal proteins (RP) play key roles in the regulation of apoptosis, multidrug resistance and carcinogenesis. The aim of this study was to investigate the expression of ribosomal protein L36 (RPL36) in hepatocellular carcinoma (HCC) and to correlate it with clinicopathological parameters and clinical outcome. Liver specimens were obtained from 60 HCC patients who had undergone a partial hepatectomy. Expression of RPL36 in tumor tissue and surrounding non‐tumorous tissues was evaluated on a tissue microarray by immunohistochemistry. RPL36 was expressed in 45 of 60 (75%) HCC by immunohistochemistry, but was not detected in corresponding non‐tumors. RPL36 expression correlated significantly with serum levels of albumin (<I>P</I>= 0.044) and prothrombin time (<I>P</I>= 0.026), which reflect liver synthetic function. Moreover, expression of RPL36 was found to be higher in patients with early tumor stages (I/II) (<I>P</I>= 0.038) or without portal vein thrombosis (<I>P</I>= 0.005). In univariate analysis, patients with RPL36 expression revealed better overall survival (<I>P</I>= 0.037). By multivariate survival analysis, RPL36 expression was found to be an independent prognostic factor for overall survival (<I>P</I>= 0.026). Our data suggest that RPL36 may be involved in the early stage of hepatocarcinogenesis, and it can be used as an independent and potential prognostic marker for resected HCC.</P>
( Myeong Jun Song ),( Si Hyun Bae ),( Sung Won Lee ),( Do Seon Song ),( Young June Lee ),( Ho Jong Chun ),( Jong Young Choi ),( Seung Kew Yoon ),( Nam Ik Han ),( Sang Wook Choi ),( Young Sok Lee ),( C 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: The purpose of this study was to evaluate the recurrence of hepatocellular carcinoma and the survival rate of patients who received radiofrequency ablation (RFA) after transarterial chemoembolization (TACE) with that of patients treated with TACE or RFA alone. Methods: Two-hundred and one patients with HCC were consecutively enrolled at Seoul St. Mary`s hospital between Dec, 2004 and Feb, 2010. Inclusion criteria were a single HCC≤5.0 cm or up to three HCCs≤3.0 cm, with no vascular invasion or extrahepatic metastasis. In all, HCC patients (n=87) who had undergone RFA after TACE and those who received TACE (n=71) or RFA only (n=43) were analyzed. Propensity scores were generated to select from each arm of the study. Results: Median follow-up periods were 33.3 months (6.8-80.9 months). The recurrence rates at 1, 3, and 5 years in the TACE+RFA and RFA groups were similar (6, 33, and 54%; and 10, 31, and 48% respectively); however, those in the TACE group were higher (17, 58, and 78%, respectively). In the TACE+RFA group, the local recurrence rates were significantly lower compared with the RFA group (P=0.034). The overall survival rates at 1, 3, and 5 years in the TACE+RFA group (98, 95, and 90%, respectively) were superior to those in the TACE or RFA groups (98, 90, and 83%; 94, 84, and 71%; P=0.064, 0.011, respectively). In a multivariate analysis of overall survival using a Cox regression model, combination treatment was a significant independent factor for survival compared to RFA and TACE monotherapy (HR, 0.371; 95% CI, 0.141-0.973; P=0.0371, HR, 0.476; 95% CI, 0.230-0.986; P=0.046, respectively) Conclusion: The combination of TACE and RFA is an effective treatment for early-stage HCC and results in lower local recurrence and better overall survival rates than those achieved by RFA or TACE alone.
( Myeong Jun Song ),( Si Hyun Bae ),( June Sung Lee ),( Sung Won Lee ),( Do Seon Song ),( Chan Ran You ),( Jong Young Choi ),( Seung Kew Yoon ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.2
Background/Aims: We compared the recurrence of hepatocellular carcinoma (HCC) and the survival of patients who received radiofrequency ablation (RFA) after transarterial chemoembolization (TACE) with patients treated with TACE or RFA alone. Methods: This study included 201 patients with HCC, who were consecutively enrolled at Seoul St. Mary’s Hospital between December 2004 and February 2010. Inclusion criteria were a single HCC≤5.0 cm or up to three HCCs≤3.0 cm. We used a propensity score model to compare HCC patients (n = 87) who received RFA after TACE (TACE + RFA) with those who received TACE (n = 71) or RFA alone (n = 43). Results: The median follow-up period was 33.3 months (range, 6.8 to 80.9). The TACE + RFA group showed significantly lower local recurrence than the RFA or TACE groups (hazard ratio [HR], 0.309; 95% confidence interval [CI], 0.130 to 0.736; p = 0.008; and HR, 0.352; 95% CI, 0.158 to 0.787; p = 0.011, respectively). The overall survival was significantly better in the TACE + RFA group compared to the RFA group (HR, 0.422; 95% CI, 0.185 to 0.964; p = 0.041). However, the survival benefit was not different between the TACE + RFA and TACE groups (p = 0.124). Subgroup analysis showed that among patients with a tumor size < 3 cm, the TACE + RFA group had significantly better long-term survival than those in the TACE or RFA groups (p = 0.017, p = 0.004, respectively). Conclusions: TACE + RFA combination treatment showed favorable local recurrence and better overall survival rates in early-stage HCC patients. Patients with tumors < 3 cm are likely to benefit more from TACE + RFA combination treatment. Additional studies are needed for the selection of suitable HCC patients for TACE + RFA treatment.
( Myeong Jun Song ),( Do Seon Song ),( Hee Yeon Kim ),( Sun Hong Yoo ),( Chung Hwa Park ),( Si Hyun Bae ),( Jong Young Choi ),( U Im Chang ),( Jin Mo Yang ),( Seung Kew Yoon ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: Transarterial chemoembolization (TACE) has been widely used as treatment in hepatocellular carcinoma. In order to maximize the therapeutic efficacy, Doxorubicin loaded drug eluting bead has been developed to deliver higher doses of chemotherapeutic agent and to prolong contact time with tumor. The purpose of this study was to evaluate the efficacy and safety of DC bead® TACE in comparison with conventional TACE. Methods: One hundred twenty nine patients who underwent TACE between Aug. 2008 and Feb. 2011 were retrospectively enrolled. We compared HCC patients (n=60) who had underwent TACE with DC bead® to controls (n=69) who had received conventional TACE. The primary endpoint was treatment response according to modified RECIST criteria, time to recurrence and overall survival. The primary safety endpoint was treatment-related liver toxicity. Results: The objective response rates of the DC bead® group were significantly better than that of conventional TACE group (81.6 vs 49.2 %, p <0.001). Subgroup analysis conducted in patient with intermediate stage confirmed significantly higher objective response and longer time to progression rates in patients receiving DC bead® than those treated with conventional TACE (p<0.001, p=0.038, respectively). DC bead group showed significant overall survival benefit (p=0.005). There was no statistically significant difference in liver toxicity between the DC bead® and conventional TACE group (p>0.05). Conclusions: Transarterial chemoembolization with DC bead® showed better treatment response and time to progression rates compared with conventional TACE. DC bead® TACE may appear to be a feasible and promising approach in the treatment of HCC.