傷寒論에 대한 精神醫學的 硏究

文相泰,辛容玹,具炳壽 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.1

This study was aimed to get the course which is caused by Neuropsychiatric symptoms in Sang-Han. Therefore this study is based on 『Euhak-Ipmun. Sang-Han』(『醫學入門.傷寒』) classfied mainly by symptoms. The results were summerized as follows: 1. Neuropsychiatric symptoms in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』) are explained as Pal-Gang(八綱), which shows those are settled down to a systematic oriental medical theory. 2. Pal-Bup (八法) used in the cure of symptomatische psychose in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』), which is intended to boost the effect of cure, choosing the respondent cure method about various causes. 3. Pal-Gang(八綱) and Pal-Bup(八法) in『Euhak-Ipmun. Sang-Han』(『醫學入門·傷寒』) are improved by Lee-Chun(李 ) who added Jang-gi(張機)'s Sang Han theory and new medical thought in the ages of Geum. Won. 4. Lee-Chun(李 ) believed that Neuropsychiatric symptoms which appeared in Sang Hang is caused by the "Unbalance(不平)". So he wanted to reach harmony of "Jeong(精), QI(氣), Shin(神), Hyul(血)" after improving the status of "Unbalance(『不平』)" toward the status of "Balance(平)".

The Evolving Policy Debate on Border Closure in Korea

Su-Jin Kang,Jihyun Moon,Heewon Kang,Heekyoung Nam,Sangwoo Tak,Sung-Il Cho 대한예방의학회 2020 Journal of Preventive Medicine and Public Health Vol.53 No.5

302 Copyright © 2020 The Korean Society for Preventive Medicine J Prev Med Public Health 2020;53:302-306 • https://doi.org/10.3961/jpmph.20.213 The Evolving Policy Debate on Border Closure in Korea SuJin Kang1, Jihyun Moon2, Heewon Kang1, Heekyoung Nam3, Sangwoo Tak1, Sung-il Cho1,3 1Institute of Health and Environment, Seoul National University, Seoul, Korea; 2Samsung Advanced Institute of Health Science and Technology, Sungkyunkwan University, Seoul, Korea; 3Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Korea Brief Report Objectives: In this paper, we aimed to investigate the evolving debate over border closure in Korea during the coronavirus disease 2019 (COVID-19) pandemic, to address the main themes associated with border closure, and to discuss the factors that need to be considered when making such decisions. Methods: We collated and reviewed previously conducted review studies on border closures during infectious disease outbreaks to derive relevant themes and factors. Results: According to our systematic review on border closures and travel restrictions, the effects of such containment efforts are limited. We suggest considering the following factors when determining whether to impose border closure measures: (1) disease characteristics, (2) timeliness of implementation, (3) transmission delay and the basic reproduction number, (4) globalization and pandemics, and (5) social and economic costs. Conclusions: Our assessment indicates that the effects of border closures are at best temporary and limited. Alternative measures must be contemplated and implemented to suppress the spread of COVID-19 in particular and infectious diseases more broadly.

중증 외상환자에서 염기 결핍수치의 유용성

문준동,김수진,문철규,최성혁,전정민,이성우,홍윤식 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: This study's objective was to determine the prognostic value of the base deficit measured in the emergency department(ED) and to determine whether base deficit can provide information not provided by advanced injury scoring system. Methods: This study was a retrospective analysis of data collected for two years. Thirty-two severe trauma patients who were admitted to the Emergency Department of Korea University Hospital were included in this study. The patients were divided into two groups: the normal base deficit group(-3 mmol/L to 3 mmol/L) and the elevated base deficit group(>3 mmol/L). The base-deficit value, age, sex, head injury, organ failure rate, and survival were considered, and the also Revised Trauma Score(RTS), Acute Physiology And Chronic Health Evaluation(APACHE II), and Injury Severity Score(ISS) were measured. Result: The elevated base-deficit group showed a lower survival rate and a higher organ failure rate compared to the normal base deficit group. Logistic Regression showed a strong association between base deficit and mortality rate. Among the previous injury scoring Systems(RTS, APACHE II, ISS), base deficit had the strongest correlation with RTS. By using base deficit value and the RTS together, we obtained a higher positive predictive value than that obtained by using base deficit or RTS alone. Conclusion: The admission value of the base deficit in the ED is a useful tool in predicting the outcome in severe trauma patients, and it can be an adjunct to previous injury scoring systems. As an advanced injury scoring System is developed in the future, the base deficit may have some significant role.

항치매성 acetylcholineaterase 함유 검은 비늘버섯 추출물의 PC12 신경세포사 저해 효과

문정수, 한상민, 이종수 배재대학교 자연과학연구소 2021 自然科學論文集 Vol.32 No.1

본 연구에서는 부분 정제된 acetylcholinesterase 저해물질을 함유한 검은비늘버섯 추출물의 신경세포 PC12에 대한 세포독성을 조사하고 PC12 신경세포 저해효과를 조사하였다. 검은 비늘버섯 추출물은 세포 생존에 영향을 미치지 않았고 무처리군의 85.6%에 비해 19.3%로 세포사 저해효과가 우수하였다. Dementia disease has been increased because of the significant increase in life expectancy over sixty-five years of age in Korea. This studies were carried out to develop new anti-dementia compounds such as acetylcholinesterase(AChE) inhibitor from edible mushrooms.. AChE inhibitor from water extract of finally selected Pholiota adiposa were partially purified by Sephadex G-50 gel permeation chromatography and RP-HPLC. The partial purified acetylcholinesterase inhibitor-containing Pholiota adiposa extracts showed high cell viability and also showed apoptotic inhibitory effects against PC12 neuron-like cells.

검은 비늘버섯 Pholiota adiposa로부터 항치매성 Butyrylcholinesterase 저해물질의 생산

한상민, 박선정, 문정수, 이종수 배재대학교 자연과학연구소 2021 自然科學論文集 Vol.32 No.1

본 연구에서는 식용버섯 유래의 새로운 항치매성 butyrylcholinesterase(BChE) 저해물질을 생산할 목적으로 식용버섯 추출물들의 BChE 저해활성을 측정하였다. 식용버섯들 중에서는 검은비늘버섯의 물 추출물이 42.7 %의 BChE 저해활성을 보여 최종 선발하였다. 또한 검은비늘버섯 자실체를 30 ℃에서 24시간 물 추출하였을 때 BChE 저해활성이 가장 높았다. n this paper, screening potent edible mushroom with high anti-dementia butyrylcholinesterase(BChE) inhibitory activity and optimal extraction condition of BChE inhibitors were described. Among various edible mushroom, the water extract from Pholiota adiposa fruiting body had high BChE inhibitory activity of 42.7 %. BChE inhibitor from P.adiposa fruiting body was maximally extracted when its fruiting body was trated with distilled water for 24 hr at 30 ℃.

서로 다른 이중에너지 방사선흡수기계 기종 (Hologic QDR 4500-A 와 Lunar EXPERT-XL)간의 골밀도 교차 보정

문대혁,김기수,이희경,김재승,신중우,조진만,김상욱 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

Purpose: A cross-calibration equation is needed to compare bone mineral density measured by different dual X-ray absoptiometry systems. We performed this study to establish appropriate cross-calibration equations between two different dual X-ray absorptiometry systems. Materials and Methods: Bone mineral density of anterior-posterior lumbar spine (L2-4 level) and femoral neck were measured in 109 women (55±11yr) using two different dual X-ray absorptiometry systems (Lunar EXPERT-XL) and Hologic QDR 4500-A). Bone mineral density values measured by two systems, including area, bone mass content, bone mineral density and percentile of young normals were compared and cross-calibration equations between two systems derived. Results: The bone mineral density values of 109 women measured by Lunar system were 0.958±0.17 g/cm2 at L2-4 and 0.768±0.131 g/cm2 at femur neck, which were significantly higher (13±6% at L2-4 and 19±7% at femur neck, p<0.001) than those (0.851±0.144 g/cm2 at L2-4 and 0.649±0.108 g/cm2 a neck) by Hologic system. Bone mineral content and percentile of young normals measured by Lunar system were also significantly higher than those by Hologic system (p<0.001), whereas there was no difference in area (p>0.05). There was a high correlation between bone mineral density values of L2-4 and femoral neck obtained with both dual X-ray absortiometry systems (r=0.96 and 0.95, respectively). Cross-calibration equations relating the bone mineral density were Lunar=1.1287×Hologic-0.0027 for L2-4 and Lunar=l.1556×Hologic+0.0l82 for femoral neck. Conclusion: We obtained cross-calibration equations of bone mineral density between Lunar EXPERT-XL and Hologic QDR 4500-A. These equations can be useful in comparing bone mineral density obtained by different dual X-ray absorptiometry systems.

조기진통의 진단과 처치

성문수,김현찬 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Prematurity and intra-uterine growth retardation(IUGR) and two main cause of low birth weight(LBW), a major contributor to infant mortality. The majority of LBW infants in developing countries is due to IUGR, while most LBW infants in industrialized countries are due to preform birth. The preform birth rate of almost 10% of birth has remained little changed for several decades, despite in changes in clinical practice and technology. Between 75~80% of those deliveries are due to either preform labor or preform prematurity of membranes. There is not yet complete understanding of the cause of preform labor. Preventive and treatment efforts aimed at single etiology have been unsuccessful to date, since the cause are multifactorial. Accurate diagnosis of preform labor remains a problematic issue. New techniques such as transvaginal cervical sonography and fetal fibronectin are increasingly important in diagnosis and intervention planning. Neither test can, at present, recommended for screening of general population since there is no effective intervention for a positive test. Future directions in research include development of new tocolytic agents and clarification of the best use of adjunctive therapies for lung maturity.

LiNbO₃: (Mg+Mn) 단결정의 광흡수

김상수,정문영 昌原大學校 基礎科學硏究所 1995 基礎科學硏究所論文集 Vol.7 No.-

Transition metal manganese(Mn) has been chosen as a marking impurity, and three kinds of manganesedoped LiNbO₃crystals have been grown by the Czochalski method. Their [Li]/[Nb] ratio and contents of MgO in the growing melt are 0.945 + 0 mole % MgO, 0.945 + 4.5 mole % MgO and 0.945 + 6.0 mole % MgO, respectively. The amount of MnO in the crystals is 0.1 mole %. The measurements of UV absorption edge and ?? absorption bands in these crystals were made at room temperature. The position of the UV absorption edge and the shape and peak point of the absorption band of the ?? vibrational band changed monotonously up to a critical concentration of ?? ions. The mechanism of the incorporation of ?? ions changes at this concentration. As experimental results showed, the significant difference between them revealed that the ionic environment of ?? cation in the 0.945 + 0 or 4.5 mole % MgO and 0.945 + 6.0 mole % MgO is different. According to this, the ?? cation should substitute for ?? in 0.945 +6.0 mole % MgO crystal rather than substitute for ?? in 0.945 + 0 or 4.5 mole % MgO.

점성토(c-Ф 흙)로 뒤채움된 중력식 옹벽에서 인장규열을 고려한 수평토압 : 배수해석

정성교,남선우,김문규,오병수 東亞大學校 建設技術硏究所 1997 硏究論文集 Vol.21 No.2

Coulomb’s theory has been usually used in practice for design of retaining walls. This theory assumed that the lateral earth pressure was a triangular distribution, because the point of applying the thrust could not be abtained straightforward. However, the results of laboratory and filed tests proved that the lateral earth pressure was not a triangular distribution. In this study, for gravity walls with inclined backface, backfilled by c - ø soils with inclined surface, an analytical method for earth pressure has been derived. This method applied the flat arching concept and the Coulomb’s wedge, under drained condition, for the cases of considering tension crack. In addition, this paper is dealt with comparing the new analytical solution with existed theories for some cases.

[논문]다른 온도로 소성한 왕겨를 콘크리트 흔화재로 사용한 콘크리트의 강도특성에 관한 연구

신상엽,정의창,정유진,박문석,백계승,최세윤,김영수 釜山大學校生産技術硏究所 2007 生産技術硏究所論文集 Vol.66 No.-

본 논문은 다른온도로 소성한 왕겨를 콘크리트 흔화재로 사용한 콘크리트의 강도특성을 알아보기 위한 것으로 물결합재비를 35% 로 고정하고 왕겨의 혼입률을 각기 달리하여 소성온도에 따른 압축강도 특성과 왕겨의 혼입률에 따른 강도특성을 평가하였다. 실험결과 왕겨가 혼화재로서 성능을 발휘하는 최저 온도가 600℃인 것으로 나타났으며, 700℃로 소성한 경우 가장 우수한 강도 값을 나타내었다. 또한 혼입률별 압축강도 특성에서는 혼입률 10% 에서 가장 우수한 강도발현을 나타내었다.