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한국인 가족성 용종증 환자의 가계도 분석 - 한국 용종증 등록소 -
박규주 ( Kyu Joo Park ),박재갑 ( Jae Gahb Park ),최규완 ( Kyoo Wan Choi ),원치규 ( Chi Kyooh Won ),김광연 ( Kwang Yun Kim ),김세민 ( Sea Min Kim ),김영진 ( Young Jin Kim ),김용일 ( Yong Il Kim ),김응국 ( Eung Kook Kim ),김종훈 ( J 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5
Familial adenomatous polyposis (FAP) is a disease characterzed by the development of 100 to several thousand colorectal adenomas, of which one or more will degenerate into carcinoma unless prophylactic colectomy is performed. It is characterized by autosomal dominant mode of inheritance, but sporadic cases without family history of the disease has been reported in up to one-third of patients. (continue...)
( Su Yeon Lee ),( Kyooh Yun Kim ),( Hyun Jin Kim ),( Sang Yeob Yeo ) 한국환경생물학회 2013 환경생물 : 환경생물학회지 Vol.31 No.1
Oil spills have occurred throughout the years of industrialization and represent a global challenge as they affect vast areas of the ocean. The toxicity of crude oil to aquatic organisms has been extensively investigated, but the potential impacts of crude oil on vertebrate development remain largely unknown. Here, we investigated the effects of dispersants used in treating a recent oil spill, as well as that of crude oil, on vertebrates by using the zebrafish (Danio rerio) model species, which has been widely used in empirical studies of both early embryonic development and adult physiology. Chronic exposure to crude oil resulted in marked developmental abnormalities, including pericardial edema, abnormal trunk vessel development, retardation of axonal branching, and abnormal jaw development. Embryonic development was affected more severely by exposure to the oil-dispersant combination than to the oil alone. Thus, the zebrafish in vivo model system suggests that dispersant treatment can have detrimental developmental effects on vertebrates and its potential impact on marine life, as well as humans, should be carefully considered in clean-up efforts at the site of an oil spill.