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18F-FDG PET/CT Findings of Scrub Typhus
Kim, Jahae,Kwon, Seong Young,Kang, Sae-Ryung,Cho, Sang-Geon,Song, Ho-Chun Lippincott 2015 Clinical nuclear medicine Vol.40 No.10
ABSTRACT: Scrub typhus is an acute infectious disease caused by Orienta tsutsugamushi, which is clinically manifested by fever, generalized lymphadenopathy, diffuse myalgia, headache, maculopapular rash, and eschars at the site of chigger feedings. Diagnosis of scrub typhus requires compatible clinical features, history of exposure, and result of selorogic testing. In recent years, F-FDG PET/CT is seen as having increasing potential for use in examination and management of patients with infectious or inflammatory disorders. This is a PET/CT case demonstrating scrub typhus in a patient without evidence of recurrence of thyroid papillary cancer.
Kim, Jahae,Yoo, Su Woong,Kang, Sae-Ryung,Cho, Sang-Geon,Oh, Jong-Ryool,Chong, Ari,Min, Jung-Joon,Bom, Hee-Seung,Yoon, Jung-Han,Song, Ho-Chun The Korea Society of Nuclear Medicine 2012 핵의학 분자영상 Vol.46 No.4
Purpose We investigated whether PET indices measured by $^{18}F$-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) can predict prognosis in patients with operable primary breast cancer. Methods We reviewed 53 patients with operable primary breast cancer who underwent pretreatment FDG PET/CT. PET indices, maximum standardized uptake value (SUV) and metabolic tumor volume (MTV), were measured in the primary breast tumor (P), metastatic lymph nodes (N) and total tumor (T). The Cox proportional hazards model was used with age, tumor size, clinical lymph node status, method of surgery, presence or absence of neoadjuvant chemotherapy, histological type, histological grade, hormone receptors and HER2 status to predict disease-free survival (DFS) and overall survival (OS). Results Median follow-up period was 50 months (range, 17-73 months), during which 17 patients had recurrent disease and nine of whom died. The univariate analysis showed that high SUV of N ($N_{SUV}$, P=0.011), MTV of N ($N_{MTV}$, P=0.011) and MTV of T ($T_{MTV}$, P=0.045) as well as high histological grade (P=0.008), negative estrogen (P=0.045) and negative progesterone (P=0.029) receptor status were associated with shorter DFS. High $N_{SUV}$ (P=0.035), $N_{MTV}$ (P=0.035) and $T_{MTV}$ (P=0.035) as well as high histological grade (P=0.012) and negative estrogen receptor status (P=0.009)were associated with shorter OS. $N_{SUV}$, $N_{MTV}$ and $T_{MTV}$ were found to be significantly associated with high histological grade (P=0.005). However, those failed to be statistically significant prognostic factors on multivariate analysis. Conclusions PET indices seem to be useful in the preoperative evaluation of prognosis in patients with operable primary breast cancer. $N_{SUV}$, $N_{MTV}$ and $T_{MTV}$ might be considerable factors associated with patient outcome in operable breast cancer.
이환모,김호중,김긍년,안풍기,천자혜,김양수,신혜선,김인숙,정혜경,김영아,채형기,박인영 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2
연구배경: 수술적 치료가 필요한 척추관협착증 환자들은 주로 60세 이상의 고령환자로장기간의 입원 시 기회 감염의 증대와 불필요한 의료비의 증대를 가져오게 되며, 수술후환χ}들의 재원일수의 증가는병원의 병상가 동률을감소시키고, 전공의에게는불필요한 업무를 증가시킨다. 연구목적: 비용·효과면에서 최적화된 진료지침의 개발은 불필요한 의료비의 감소및 Hospital Induced Complication을 줄여 환자만족도를증진시킬 수 있으며, 각 환자에 대한전공의 업무를 줄일 수있다. 의료기관: 서울특별시에 소재한 2,075병상의 종합전문 요양기관 연구방법: 정형외과및 신경외과의 척추관협착증환자 의 처방을 비교하여 최적의 표준진료지침을 개발하고 최종적으로 CP Master Program (EMR 프로그램)에 입력하여 환자에게 적용하였다. 연구결과': CP 적용전, 후비교를통해 재원일수는 3.8일 이 감소하였으며, 이에 따라 병상가동률 및 진료수익이 증가했으리라고 예상되며 현재 비교검토중이다. 또한,CP 개발및 CP Master Program의 사용을 통한 전공의 업무감소에 대해 검토하고 있다.
Cho, Sang-Geon,Jabin, Zeenat,Park, Ki Seong,Kim, Jahae,Kang, Sae-Ryung,Kwon, Seong Young,Jeong, Geum-Cheol,Song, Minchul,Kim, Jong Sang,Cho, Jae Yeong,Kim, Hyun Kuk,Song, Ho-Chun,Min, Jung-Joon,Bom, H Springer-Verlag 2017 European Journal of Nuclear Medicine and Molecular Vol.44 No.2
<P>LVMD measured by GMPS showed added prognostic value in acute MI with multivessel disease. GMPS could serve as a comprehensive evaluation imaging tool in patients with acute MI and multivessel disease.</P>
이환모,김호중,김긍년,안풍기,천자혜,신현주,김양수,신혜선,김인숙,정혜경,김영아,채형기,박인영,Lee, Hwan Mo,Kim, Ho Jung,Kim, Keung Nyun,Ahn, Poong Gi,Chun, Jahae,Shin, Hyun-Ju,Kim, Yang Soo,Shin, Hye Sun,Kim, In Sook,Chung, Hye Kyung,Kim, You 한국의료질향상학회 2009 한국의료질향상학회지 Vol.15 No.2
연구배경: 수술적 치료가 필요한 척추관 협착증 환자들은 주로 60세 이상의 고령환자로 장기간의 입원 시 기회 감염의 증대와 불필요한 의료비의 증대를 가져오게 되며, 수술 후 환자들의 재원일수의 증가는 병원의 병상가동률을 감소시키고, 전공의에게는 불필요한 업무를 증가시킨다. 연구목적: 비용 효과면에서 최적화된 진료 지침의 개발은 불필요한 의료비의 감소 및 Hospital Induced Complication을 줄여 환자 만족도를 증진시킬 수 있으며, 각 환자에 대한 전공의 업무를 줄일 수 있다. 의료기관: 서울특별시에 소재한 2,075병상의 종합전문요양기관 연구방법: 정형외과 및 신경외과의 척추관 협착증 환자의 처방을 비교하여 최적의 표준진료지침을 개발하고 최종적으로 CP Master Program(EMR 프로그램)에 입력하여 환자에게 적용하였다. 연구결과: CP 적용 전, 후 비교를 통해 재원일수는 3.8일이 감소하였으며, 이에 따라 병상 가동률 및 진료수익이 증가했으리라고 예상되며 현재 비교 검토 중이다. 또한, CP 개발 및 CP Master Program의 사용을 통한 전공의 업무 감소에 대해 검토하고 있다.
Yoo, Su Woong,Kim, Jahae,Chong, Ari,Kwon, Seong-Young,Min, Jung-Joon,Song, Ho-Chun,Bom, Hee-Seung The Korea Society of Nuclear Medicine 2012 핵의학 분자영상 Vol.46 No.4
Purpose This study aimed to further stratify prognostic factors in patients with stage IV non-small cell lung cancer (NSCLC) by measuring their metabolic tumor volume (MTV) using F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT). Materials and Methods The subjects of this retrospective study were 57 patients with stage IV NSCLC. MTV, total lesion glycolysis (TLG), and maximum standardized uptake value (SUVmax) were measured on F-18 FDG PET/CT in both the primary lung lesion as well as metastatic lesions in torso. Optimal cutoff values of PET parameters were measured by receiver operating characteristic (ROC) curve analysis. Kaplan-Meier survival curves were used for evaluation of progression-free survival (PFS). The univariate and multivariate Cox proportional hazards models were used to select the significant prognostic factors. Results Univariate analysis showed that both MTV and TLG of primary lung lesion (MTV-lung and TLG-lung) were significant factors for prediction of PFS (P<0.001, P=0.038, respectively). Patients showing lower values of MTV-lung and TLG-lung than the cutoff values had significantly longer mean PFS than those with higher values. Hazard ratios (95 % confidence interval) of MTV-lung and TLG-lung measured by univariate analysis were 6.4 (2.5-16.3) and 2.4 (1.0-5.5), respectively. Multivariate analysis revealed that MTV-lung was the only significant factor for prediction of prognosis. Hazard ratio was 13.5 (1.6-111.1, P=0.016). Conclusion Patients with stage IV NSCLC could be further stratified into subgroups of significantly better and worse prognosis by MTVof primary lung lesion.
Brain Metastases Mimicking Hyperostosis Frontalis Interna on 99mTc HDP Bone Scintigraphy
Kang, Sae-Ryung,Kim, Jahae,Kwon, Seong Young,Min, Jung-Joon,Bom, Hee-Seung,Sohn, Myung-Hee,Song, Ho-Chun Wolters Kluwer Health, Inc. All rights reserved. 2016 Clinical nuclear medicine Vol.41 No.10
<P>Symmetric bifrontal uptake of bone-seeking agents is usually considered as the main feature of hyperostosis frontalis interna in postmenopausal elderly women. This finding is not uncommon in elderly women because of the change in their hormonal level. However, in the present case, a 66-year-old woman with intra-axial brain metastases of breast cancer showed symmetric bifrontal uptake on bone scintigraphy. Therefore, symmetric bifrontal uptake should not always be considered as a definite indicator of hyperostosis frontalis interna. Further evaluation such as SPECT/CT is needed for evaluation of brain metastases especially in cancer patients.</P>