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      • KCI등재후보
      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • KCI등재
      • 뉴로-퍼지 가중치 제어 신경망 구조

        朴秀峰,金在珥 東新大學校 1995 論文集 Vol.7 No.-

        In the learning of the neural network, Learning rate largely depends on the algorithm of network implementation, and is closely related to the weight length and computing speed. In this paper, we propose an algorithm to design digital logic systems and hardware using weighted control neural network with neuro-fuzzy architecture. The network for weight-control based on the mathmetical proposition has been proposed. The proposition use AT MOST n, AT LEAST n. The proposed algorithm has been applied to design JK flip-flop and ROM. The simulations shows that the proposed algorithm can simplify design of hardware, improve processing speed of system and implement synapse with good learning in the large neural network.

      • KCI등재
      • SCOPUSSCIEKCI등재

        Transthyretin의 Glutathione 자동산화 촉진작용

        박종근,정신,김재휴,김수한,강삼석,이제혁,안봉환 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.8

        When reduced glutathione(GSH) was incubated at neutral pH and at 37°, its concentration decreased slowly with formation of oxidized glutathione(GSSG). Autooxidation of GSH was accelerated by Cu^(2+) and Hg^(2+), but not by other common mono-, di-, and tri-valent cations. Transthyretin was found to stimulate autooxidation of GSH in the presence or absence of Cu^(2+) and Hg^(2+). EDTA inhibited perfectly the autooxidation of GSH regardless of the presence of transthyretin. The stimulating activity of transthyretin was maximal at pH 7.0, declining progressively with increase or decrease of pH from 7.0. Sulfhydryl-blocking agents such as p-hydroxymercuribenzoic acid and Nethylmaleimide markedly inhibited the stimulating activity of transthyretin. Transthyretin stimulated autooxidation of other sulfhydryl compounds such as clithiothreitol and cysteine. However, it did not show a significant effect on autooxidation of sulfhydryl group of egg albumin and eye lens proteins. And transthyretin did not cause any oxidative change to thyroxine(T₄), 3, 5, 3Ltri iodo thyronine(T₃) and 3, 3: 5~triiodothpnine(rT₃) bound to it in the presence of GSH and Cu^(2+). The above results suggest that transthyretin may play a role in regulation of oxidized status of sulfhydryl groups in blood plasma and cerebrospinal fluid

      • KCI등재후보

        중재제도유용성과 부산지역기업들의 인식도에 관한 실증적 연구

        박봉규,신군재 韓國仲裁學會 2005 중재연구 Vol.15 No.3

        In the era of globalization firms must operate all useable resources into marketing activities to survive on the unlimited competition. However, firms face many kinds of disputes with counterparts because of aggressive marketing activities. There are two ways of solving these disputes : litigation and arbitration. As compared to litigation, arbitration is more popular because of such merits as the enforcement of arbitral award in foreign countries, the single trial system, the settlement by specialists, and the confidential proceedings. This paper examines trade firms' perception on the arbitration system and the effects of the advantages of arbitration and quality of arbitrators on the outcome of arbitration. The results show that the advantages of arbitration and quality of arbitrators influenced positively on the outcome of arbitration, but influenced nagatively on the colsed-door of arbitration procedures and a fair procedure of arbitrator. Though this paper has several limitations, this paper may contribute to figure out the relationship between arbitration merits and quality of arbitrator and outcomes as a first empirical paper and to suggest future research method and direction.

      • 열처리된 AgInS₂박막의 defect 연구

        박창선,김봉재,홍광준 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.1

        AgInS₂단결정 박막은 수평 전기로에서 합성한 AgInS₂다결정을 증발원으로하여, hot wall epitaxy(HWE) 방법으로 증발원과 기판(반절연성-GaAs(100))의 온도를 각각 680℃, 410℃로 고정하여 단결정 박막을 성장하였다. 이때 단결정 박막의 결정성은 광발광 스펙트럼과 이중결정 X-선 요동곡선(DCRC)으로부터 구하였다. Hall 효과는 van der Pauw 방법에 의해 측정되었으며, 293K에서 운반자 농도와 이동도는 각각 9.35×10^(16)/㎤, 294 ㎠/V·s였다. 또한 광흡수 spectra에서 energy band gap의 온도 의존성 E_(g)(T)는 2.3165eV-(9.89×10_(-3)eV/K)T² / (T+2930K)임을 확인하였다. 성장된 AgInS₂단결정 박막을 Ag, S, In 분위기에 열처리하여 10K에서 photoluminescience(PL) spectra를 측정하여 점 결함의 기원을 알아보았다. PL 측정으로부터 얻어진 V_(Ag), Vs, Ag_(int), 그리고 S_(int)는 주개와 받개로 분류되어졌다. AgInS₂단결정 박막을 S분위기에서 열처리하면 p형으로 변환됨을 알 수 있었고, In 분위기에서 열처리하면 열처리 이전의 PL spectra를 보이고 있어서 I₂, I₁ 및 S, A emission에 의한 PL peak에는 영향을 주지 않는다고 보았다. A stoichiometric mixture of evaporating materials for AgInS₂single crystal thin films was prepared from horizontal furnace. To obtain the single crystal thin films, AgInS₂ mixed crystal was deposited on thoroughly etched semi-insulating GaAs(100) substrate by the Hot Wall Epitaxy(HWE) system. Temperature of the source and substrate were 680℃ and 410℃, respectively. The crystalline structure of the single crystal thin films was investigated by the photoluminescence and double crystal X-ray diffraction (DCXD). The carrier density and mobility of AgInS₂single crystal thin films measured from Hall effect by van der Pauw method are 9.35×10^(16)cm^(-3) and 294 cm²/V·s at 293 K, respectively. From the optical absorption measurement, the temperature dependence of the energy band gap bn-AgInSz single crystal thin films was found to be E_(g)(T) = 2.1365 eV - (9.89 x10^(-3) eV) T²/(2930 + T). After the as-grown AgInS₂single crystal thin films was annealed in Ag-, S-, and In-atmospheres, the origin of point defects of AgInS₂single crystal thin films has been investigated by using the photoluminescence(PL) at 10 K. The native defects of V_(Ag), Vs, Ag_(int), and S_(int) obtained from PL measurements were classified as a donors or acceptors type. And we concluded that the heat-treatment in the S-atmosphere converted AgInS₂single crystal thin films to an optical p-type. Also, we confirmed that In in AgInS₂/GaAs did not form the native defects because In in AgInS₂single crystal thin films did exist in the form of stable bonds.

      • 해조류 에탄올 농도별 추출물의 항돌연변이원성 및 항균성

        박제석,오명철,오창경,현재석,김봉오,김수현 濟州大學校工科大學産業技術硏究所 1996 尖端技術硏究所論文集 Vol.7 No.2

        톳. 미역 및 다시마의 에탄올 농도별 추출물이 MMS. ICR191 및 sodium azide에 의해 유도되는 돌연변이원성의 억제효과 및 E. coli, B. subtilis 및 S. serevisiae에 대한 항균효과를 검정하였다. 톳의 90% 에탄올 추출물은 MMS와 ICR191에 대한 항돌연변이 원성이 각각 70 및 95% 이상으로 매우 높았으나, sodium azide에 대한 항돌연변이원성은 없었다. 미역의 에탄올 농도별 추출물은 30∼90% 에탄올 추출물에서 50% 이상의 항돌연변이 효과를 보았으나 MMS와 sodium azide에 대한 항돌연변이 효과는 없었다. 다시마의 30∼90% 에탄올 추출물의 ICR191에 대한 항돌연변이 효과는 70% 이상이었으나, MMS와 sodium azide에 대한 효과는 없었다. 에탄올 농도별 톳의 추출물들에 대한 항균성 검색 결과 70과 90% 추출물들이 E. coli와 B. subtilis에 대하여 뚜렷한 항균효과는 미역 추출물 보다 다시마의 추출물이 더욱 요과적이었다. 미역 추출물은 50% 추출물만이 S. cerevisiae에 대한 성장저지효과를 나타낸 반면, 다시마 추출물은 90% 에탄올 추출물에서는 시험된 모든 공시균주에 대하여, 그리고 70% 에탄올 추출물에서는 E. coli와 B. sutilis에 대하여 높은 성장저지효과를 나타내었다. Desmutagenic against MMS-, ICR191- and sodium azide-induced mutations, and antimicrobial effects against Escherichia coli, Bacillus subtilis and Saccharomyces cerevisiae by the extracts from Hizikia fusiforme. Laminaria japonica and Undaria pinnatifida with ethanol of a different concentrations were investigated. Desmutagenic effects against MMS and ICR191 of 90% ethanol extracts from Hizikia fusiforme were up 70 and 95%. respectively. no against sodium azide. Desmutagenic effects against ICR191 of 30∼90% ethanol extracts from Undaria pinnatifida and Laminaria japonica were up to 50 and 70%. respectively. but no against sodium azide and MMS. Antimicrobial effect of 70 and 90% ethanol extracts from Hizikia fusiforme had potent antimicrobial activities against E. coli and B. subtilis. Ethanol extracts from Laminaria japonica showed more effective antimicrobial effects than those from Undaria pinnatifida. Only 50% ethanol extract from Undaria pinnatifida showed growth inhibition effect against S. cerevisiae. Seventy percent ethanol extract from Laminaria japonica showed growth inhibition effect against all strains tested. while 90% ethanol extract showed against E. coli and B. subtilis.

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