Pityriasis Amiantacea: An Epidemiologic Study of 44 Cases in Korean Patients

( Hyun-bin Kwak ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2020 Annals of Dermatology Vol.32 No.1

[P029] A case of miliary osteoma cutis on face

( Hyun-bin Kwak ),( Soo-han Woo ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Miliary osteoma cutis of the face is a rare variant of osteoma cutis that particularly occurs on the face of middle-aged women. Clinically, it presents as multiple skin colored papules and normochromic hardened nodules predominantly, which mimics milia. They cause therapeutic and cosmetic problem especially in women who are usually concerned. A 55-year-old woman presented with asymptomatic multiple papules on her face. She had no known relevant history of any systemic disease or medication. Physical examination revealed multiple scattered flesh colored, 3-5mm sized, hard papules on the forehead, chin, and both cheek. Under the clinical impression of milia, ablative Er-Yag laser was done, but we found crushed chalky materials from the lesion. Histopathologic findings from the lesion showed a fragment of mature bone formation in the dermis. She was finally diagnosed as miliary osteoma cutis.

Cutaneous carcinosarcoma: a clinicopathologic and immunohistochemical analysis of of 21 cases

( Hyun-bin Kwak ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Cutaneous carcinosarcoma is a rare, poorly characterized malignancy, and a biphasic tumor comprising malignant epithelial and heterogenous mesenchymal elements. Most studies on this tumor have been conducted in Caucasians. Objectives: The purpose of this study is to investigate the clinicopathologic and immunohistochemical features of cutaneous carcinosarcoma in Korea. Methods: We included 21 patients who were diagnosed with cutaneous carcinosarcoma. Results: There was a male predilection (M:F=2.5:1). The mean patient age was 70.76 years (range 43-96 years). The most common site of cutaneous carcinosarcoma was the cheek (5/21, 23.81%). Histopathologically, most tumors showed a characteristic morphological aspect consisting of two types of tumor cells, i.e. differentiated squamous cells, and spindle cells with transition zones between the two components. On immunohistochemistry, the squamous cells were positive for cytokeratin and the spindle cells showed variable expression of cytokeratin, vimentin and smooth muscle actin. Conclusion: To optimize the management of these rare tumors, correct histological diagnosis is essential. We hope this study could make some contribution to diagnosis and management of cutaneous carcinosarcoma in Korea.

Pityriasis amiantacea: a clinical and pathologic study of 39 patients

( Hyun-bin Kwak ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Pityriasis amiantacea (PA) is a unique clinical syndrome characterized by thick, asbestos-like, adherent scales engulfing tufts of scalp hairs. It occurs as a part of several inflammatory skin dermatoses. Objectives: We studied to investigate the clinical and etiopathologic characteristics of PA. Methods: We retrospectively analyzed a series of 39 PA who visited Chonbuk national university hospital from March 2008 to May 2017. Results: The mean age of the patients was 42.7 ±23.3 years (4 months ~ 79 years) with a female predominance (M:F=1:2). The most common skin diseases associated with PA was seborrheic dermatitis (30.7%), followed by psoriasis (12.8%), pemphigus (12.8%), lichen planopilaris (7.6%), folliculitis decalvans (7.6%), tinea capitis (5.1%). Five patients (12.8%) was isolated PA with no associated with other skin disease. PA was localized in 21 patients (53.8%), widespread in 13 patients (33.3%), whole scalp in 6 patients (15.3%). Scarring alopecia was detected in 6 patients (15.3%) mainly associated with primary cicatricial alopecia. Most of patients were well responded to medical treatment including antifungal agent, corticosteroid, or retinoid; however, physical removal was additionally performed in recalcitrant cases. Conclusion: PA represents a particular,exaggerated reaction pattern of the scalp result from various inflammatory and infectious skin diseases. Therefore, individualized treatment is necessary depending on the underlying skin conditions.

Dermoscopic study of tinea faciei incognito

( Hyun-bin Kwak ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Tinea incognito is a dermatopyte infection of the skin modified by previous treatments such as prolonged use of topical steroids. The diagnosis of tinea faciei incognito can be delayed or missed because of its atypical appearance without classic ringworm-like pattern. Objectives: We aims to investigate the dermoscopic findings of tinea faciei incognito and its diagnostic usefulness. Methods: We retrospectively evaluated mycologically proven 38 patients with tinea faciei incognito in our institution between July 2014 and July 2018. Results: Mean age was 59.6±20.4 years with female predominance (male:female ratio 1:1.4). Mean duration until confirmation of diagnosis was 3.4 months. Eczema-like conditions (20, 52.6%) were the most common clinical manifestation, followed by psoriasis-like (5, 13.2%) and rosacea-like (4, 10.5%) conditions. Dermoscopic patterns was observed as follows; 1) Skin: scales (81.6%), follicular pustules (44.7%), diffuse erythema and arborizing vessels (42.1%), 2) Facial vellus hairs: empty follicles (57.9%) and translucent hairs (28.9%), 3) Terminal hairs (eyebrow, beard and mustache): broken hairs (39.5%), black dots (34.2%) and empty follicles (23.7%). Conclusion: The distinct dermoscopic patterns, especially in hair follicle in this study could be usuful in clinical diagnosis of tinea faciei incognito.

Cutaneous candidiasis of the hands in an infant

( Hyun-bin Kwak ),( Eui-sung Jung ),( Sang-woo Park ),( Su-kyung Park ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

The clinical manifestations of infection with Candida species range from local mucous or cutaneous infection to widespread dissemination with multisystem organ failure. Candida species are considered to be normal flora in the gastrointestinal tract. Cutaneous candidiasis in early infancy may appear as diaper dermatosis or intertrigo. Candidiasis on the hand is considered to be a rare condition . We report a case of cutaneous candidiasis seen in a healthy 50-day-old infant. The palms showed erythematous scaly lesions of about 20 days duration. Scales in 10% potassium hydroxide solution revealed spores with pseudohyphae. The specimens were cultured on Sabouraud dextrose agar media and the white yeast-form colonies were observed. Microscopic features prepared with lacto-phenol cotton blue revealed round spores. Candida albicans was identified with internal transcribed spacer region sequencing of PCR amplified gDNA. Skin lesions were improved after 20 days without any antifungal agent.

Congenital melanocytic nevus of the nipple in a young male

( Hyun-bin Kwak ),( Eui-sung Jung ),( Sang-woo Park ),( Su-kyung Park ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Congenital melanocytic nevi occur at any site of the body. However, involvement of the nipple is very rare, with only two cases reported. Herein, we report a rare and interesting case of congenital melanocytic nevus of the nipple in a young male. A 22-year-old male presented with an asymptomatic, brown pigmented papules with cobblestone appearance on the right nipple. He and his mother stated that the lesion had been present from birth without significant changes. The breasts had no evidence of any nodularity or gynecomastia. A biopsy of the pigmented lesion on the right nipple revealed a diffuse infiltrate of small monomorphous melanocytes extending into the deep dermis. Melanocytes were also present around smooth muscle cell bundles of the nipple and mammary ducts. On the basis of clinical findings and histopathology, he was diagnosed as congenital melanocytic nevus with an unusual location.

Isolated Phthiriasis Palpebrarum in an Elderly Woman: Diagnosis and Treatment Using by Dermoscopy

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Chang-seop Lee ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.3

Isolated phthiriasis palpebrarum in an elderly woman

( Hyun-bin Kwak ),( Eui-sung Jung ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Public louse infestation caused by a blood-sucking parasite, Pthirus pubis is a worldwide public health problem that affects about 2% of the human population. Although Pthirus pubis typically infests pubic hair, it is also found on terminal hair elsewhere on the body including the axilla, chest, limbs, eyebrows, and eyelashes. Although eyelashes are a common site of Pthirus pubis infestation in children because of the lack of terminal hairs in other body areas, isolated phthiriasis palpebrarum, Pthirus pubis infestation of eyelashes and eyelids without pubic hair involvement, is very rare in adults. A 70-year-old healthy woman was presented with a 2-week history of erythema and pruritus of both eyelids. Physical examination of the eyelids showed erythematous patches and numerous black granules, which seemed to be particles of mascara. Dermoscopy revealed crab lice and ovoid nits on the eyelashes and red-brown feces on the eyelids, which were not discernible by the naked eye. There were no other lesions on the scalp, axilla, and pubis. A diagnosis of isolated phthiriasis palpebrarum was made. She was successfully treated with mechanical removal of the lice and nits with fine forceps under high-magnification videodermoscopy and topical application of 5% permethrin cream. There was no recurrence after 4 weeks of follow-up.

[P174] Nevus lipomatosus cutaneous superficialis of the sole in an infant

( Hyun-bin Kwak ),( Soo-han Woo ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Nevus lipomatosus cutaneous superficialis (NLCS) is a benign hamartomatous condition characterized by the presence of ectopic tissue in the dermis. Clinically, it is classified into two forms; multiple (classic) and solitary. The classic form presents as grouped coalescent soft, smooth plaque or nodules at birth and develops during the first three decades of life. These are most commonly seen in the pelvic girdle, with a predilection for the gluteal region. On the other hand, the solitary form usually presents as a single nodule or papule in adults and can appear at any site, including the lower trunk, knee, axillae, arm, ear or scalp. Herein, we report a rare case of NLCS occurring on the sole of an infant. To the best of our knowledge, this is the second reported case of NLCS on that rare location. A 10-month-old male infant presented with asymptomatic brown soft tumor on his right sole since birth. The infant was delivered via normal spontaneous vaginal delivery with full term. On physical examination, solitary, 0.5×0.5cm sized, soft and nontender, brown nodule was found on the left sole. In addition, he had multiple brown cafe-au-lait-like macules on both extremities. He had no any other systemic or neurological abnormalities and no family history of cutaneous diseases . Histopathologic findings of the tumor revealed grouped and strands of fat cells embedded among the collagen bundles of the dermis, which was compatible with NLCS.