목재가 선적된 선창에서 발생한 산소결핍에 의한 질식사

김동훈,김기권,장태정,김정란,이구,김수근,임현술 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

Oxygen deficiency has been frequent in a clouted space. Wood consumes oxygen and discharges carbon dioxide Instead of photosynthesis in closed space without light, so do some microorganisms on the surface. We experienced a case that a healthy Insect-proofer fell down and died of asphyxia on stair-board at 7 m below the hatch of the cargo-hold shipping wood Analysis of gases in cargo-hold revealed O2; 12.3%, CO; 105 ppm, CH4; 2.7%, and H2S; 1.9% at 1 m below the hatch, and then O2; 6.1%, CO; 220 ppm, CH4; 2.9%, and H2S, 2.3 ppm at 2.5 m below the hatch. Autopsy findings were unremarkable. We justiced the cause of death asphyxia due to oxygen deficiency. As seen in this case, the serious oxygen deficiency was accounted for oxygen consumption by wood and microorganisms.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

6C 전략에 근거한 여성 포탈 사이트의 차별화 전략에 관한 연구

김현수,김나랑,홍순구 東亞大學校 經營問題硏究所 2002 經營論叢 Vol.23 No.-

Daicel Cellulose Nitrate Cronar비적검출기에서 핵분열파편의 화학부식 특성

金炫九 조선대학교 기초과학연구소 1987 自然科學硏究 Vol.10 No.1

A series of experiments was performed to study the effect of etchant, concentration of etchant, bulk-etching rate and track diameter distribution in Daicel Cellulose Nitrate and Cronar plastic detectors. Californium-252 (cf-252) was used as a source for Spontaneous Fission Fragments (S.F.F) The bulk etching behaviour of Daicel cellulose Nitrate depends on the normality, the temperature. From the measured bulk-etching rates at different temperatures, the activation energy for bulk-etching has been obtained. The activation energy, Q, was found a value of 1.06eV for Daicel Cellulose Nitrate detector. When Cronar was etched with 6.25N, NaOH and KOH and at 69˚C, the maximum ratio of maximum length to maximum width were 6.15 and 7.07 respectively. Cronar was etched better with NaOH than with KOH at a given normality.

Daicel Cellulose Nitrate와 Cellulose Acetate 비적 검출기에서 알파입자와 핵분열파편의 특성

金炫九 조선대학교 기초과학연구소 1986 自然科學硏究 Vol.9 No.1

A series of experiments was performed to study the effect of types of etchant, concentration of etchant, bulk-etching rate, and track diameter distribution in Daicel Cellulose Nitrate (DCN) and Cellulose Acetate(CA) plastic detectors. From the measured bulk-etching rates at different temperatures, the activation energy for bulk-etching has been obtained. The activation energy, Q, was found to have a value of 0.926±0.010 eV for cellulose acetate. Caliornium-252 (cf-252) was used as a source for spontaneous fission fragments (3FF) and 1.52 MeV/nucleon α-particles, whereas 1.32 MeC/nucleon α-particles were obtained from a polonium-210 (po-210) source. We have found that the cf-252 spectrum always appears in the track diameter distribution. The optimum etching time (t_c) corresponding to the critical diameter(d_c) was obtained from the plot of track diamter vs. etching time at a given temperature. For α-particles in Daicel Cellulose Nitrate, t_c and d_c values were found to be about 64 minutes and 21, 6±0.2 ㎛, respectively.

Sodium Hydroxide용액에서 CR-39비적검출기의 부식조건 및 특성에 관한 연구

김동호,강동우,김현구 조선대학교 기초과학연구소 1988 自然科學硏究 Vol.11 No.1

A series of experiments was performed to find the optimum etching condition and the detection efficiency etc. of CR-39 track detector in order to get track detection. The CR-39 detectors It were irradiated with a 0.12 μC_i, Am-241 alpha source under a known geometrical arrangement. The detection efficiency for CR-39 detector used in this experiments was obtained about 80, 08±1.24% in the atmosphere and we concluded that 6.25N NaOH at 70℃ for 5.5hrs. represents the optimum etching condition for CR-39 detector. From the meaured bulk-etching rates at different temperatures, the activation energy for bulk-etching has been obtained. The activation energy, Q, was found to have a value of 0.73±0.O5eV for CR-39 detector.

?裂囊腫의 外科的 治驗 1例

金命來,唐鉉九 대한악안면성형외과학회 1986 대한악안면성형외과학회지 Vol.8 No.1

전착법에 의해 제작된 Ni-Fe-P 비정질 합금막의 구조적 열적 특성

김현구,문미숙 조선대학교 기초과학연구소 1998 自然科學硏究 Vol.21 No.1

A study of the fabrication and characterization of amorphous Ni-Fe-P alloys was carried out using a X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), differential scanning calorimetry (DSC) and Vickers hardness. Amorphous Ni-Fe-P alloys were electrodeposited in normal Watt's type bathe contaning FeSO_4 (10∼100g) and H_3PO_3 (0∼10g). The copper substrates with the deposited alloy was used as the working electrod, with platinum plate as the counter electrode. The electrodeposited Ni-Fe-P amorphous alloys showed broad peaks in the XRD patterns. In the EDX experiment, the Ni and P content of the alloys increased with increasing phosphoric acid concentration, whereas the Fe concent decreased with increasing P content in Ni-Fe-P amorphous alloys. In the DSC experiment, crystallization temperature (T_x), peak temperature (T_p) and enthalphy (△H) was 370.6℃, 381.8℃ and 171.6mJ/mg for current density 2A/dm^2, phosphoric acid 5g/l, and FeSO_4 20g/l concentration, respectively. The T_x, T_p, and △H increased as the ferrous sulfate concentration increased. The amorphous Ni-Fe-P deposites after being heat treated up to 450℃ produced Ni_3P, Ni_3Fe and Fe_3P. The hardness of the as-deposited Ni-Fe-P amorphous alloys was 100Hv and 150Hv after being heat treated up to 400℃ for 1h.

쌍태 임신의 임상적 고찰

김구현,송창훈 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Twin pregnancy is one of the important problems in Obstetrics because of a significantly higher morbidity and mortality than singleton pregnancy. In this study, we examined the 94 twin pregnancies among 6651 women, who deliverd in the ten year period from September, 1985 to August, 1994. The result were as follows : 1. The frequency of twin pregnancy was 94 cases among 6651 deliveries.(1:70.6) 2. In the age distribution, the predominant age group was 25-29 years. 3. The predominant parity group was nullipara. 4. The predominant gestational age group at delivery was 37-40 weeks 60.7% 5. In cases of 1st baby, the most frequent baby weight group was 2500-2999g (38.3%) followed by 2000-2499g (30.9%) and that of 2nd baby was in order of 2000-2499 (33.0%) and 2500-2999g (28.7%) respectively. 6. Both male group was predominant group (48.9%) 7. Cesarean section was done in 54.3% of the cases. 8. In 72.1% the presentation was cephalic in both babies and in 11.5%, was cephalicbreech combination 9. Concerning the delivery interval between the 1st and the 2nd baby, within 5 mins was 73.8% 10. The perinatal mortality rate of the 1st baby was 1.6% and that of the 2nd was 3.2%

대관령지역 안개의 화학조성(2002)

김현진,김만구 강원대학교 부속 환경연구소 2004 Journal of the Environment Vol.1 No.-

Cloud/fog water was collected at Daekwanreung, a typical clean environmental area, by using an active fog sampler during the foggy period in 2002. The pH ranged from 3.6 to 6.5 with a mean of 5.0, but the pH^(+) calculated from average concentrations of H^(+) was 4.4 SO₄^(2­), NO₃and NH₄^(+) were predominant ions with average concentrations of 473.3, 463.3 and 576.0ueq/ℓ, respectively. This showed that cloud/fog water was slightly acidified, but the concentrations of major pollutants were as high as those for polluted area, suggesting long range transport of pollutants. Samples were categorized into four groups(E, W, S, N) by applying 48-h back trajectory analysis using the Hybrid Single-Particle Largrangian Integrated Trajectory (HYSPLIT) model. Concentrations of seasalt (Na^(+) and CI^(-) were the highest for group E, indicating large input of seasalts by air masses transported from the East Sea. The concentrations of SO₄^(2­) were slightly higher in group N and group W than those in group S and group E. However, the concentrations of NO₃^(3­) were significantly higher in group W than those in other three groups. The medians of cloud/fog water pH for group N and W was below 4.5, which is significantly lower than those in group E and group S. This suggests that the acidifying pollutants were mainly transported from the Asia continents and cause acidification of the cloud/fog water in Daekwanreung. The large discrepancy in the concentrations of NO₃^(3­) in group N and group W showed that NO₃^(3­) was mainly transported from the Seoul metropolitan area.