http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Giuseppe Caputo ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
( Pistone Giuseppe ),( Pardo Nicola ),( Caputo Valentina ),( Castelli Elena ),( Curiale Salvatrice ),( Gurreri Rosario ),( Bongiorno Maria Rita ) 대한피부과학회 2018 Annals of Dermatology Vol.30 No.4
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab. (Ann Dermatol 30(4) 462∼464, 2018)
-
Back-analysis of a Large Landslide in a Heterogeneous Rock Mass
( Matteo Berti ),( Anna Rita Bernardi ),( Giuseppe Caputo ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2
Flysch is a sedimentary rock consisting of a rhythmic alternation of hard (limestone, sandstone, siltstone) and weak (marl, mudstone, claystone) layers. Because of the presence of layers with different physical properties the mechanical characterization of heterogeneous rock masses such as flysch is a real challenge. Different methods have been proposed in the literature to characterize flysch, combining empirical classification indexes with laboratory tests. Most of these methods, however, were specifically designed for tunneling and underground excavations and their applicability to slope stability problems is not yet fully investigated. In this study, we analyze a large landslide in a cretaceous flysch rock in order to compare the mobilized strength at failure with those predicted by the modified GSI method (Marinos and Hoek, 2001). The landslide occurred in the Savena River basin (Northern Apennines of Italy) on April 6, 2013 with a volume of about 3 million cubic meters. Soon after the failure, geological, geotechnical, and geophysical investigations were carried out to detect the failure mechanism and define the landslide geometry. Back-analyses of the failed slope were performed using both limit equilibrium and finite difference methods to estimate the in situ strength of the flysch. The results show that the mobilized rock mass cohesion is very low and that the GSI method can predict the in situ strength only assuming a very high disturbance factor. Moreover, the analysis shows that the linearization criteria proposed in literature to compute the equivalent Mohr-Coulomb parameters remarkably overestimate the rock mass strength.
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
