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- 저자 : ( Ece Yigit Taskin ) (검색결과 3 건)
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( Ece Yigit Taskin ),( Sibel Serin ),( Kevser Kutlu Tatar ),( Sema Basat ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Gastric Xanthalesmas are rare benign incidental yellow-white lesions between 0.5-10 mm in size. They are detected more frequently in female patients and the frequency of these lesions increases with age. Although the etiology of these lesions are unclear, chronic gastritis, gastrointestinal anastomosis, intestinal metaplasia, and H. pylori infection are found to be associated with GI xanthalesmas. They are usually located in antrum of the stomach in gastrointestinal tract, especially along the lesser curvature. In contrast to cutaneous xanthalesmas there is no evident association between GI xanthalesmas and hyperlipidemia. Methods: Here we present endoscopic and histological features of gastric xanthalesma in a 65 year old man with a history of chronic gastritis and iron defi ciency anemia. Results: Patient presented with iron defi ciency anemia. Upper GI endoscopy and colonoscopy has been done for investigation of the etiology. Colonoscopy showed diverticular disease of the colon. Upper GI endoscopy of the patient showed a 4mm foamy yellowish lipamatous lesion at the lesser curvature of the stomach (Image). Multiple biopsies are obtained from the lesion. The histology showed large foamy histiocytes containing a mixture of lipids in the mucosa and the submucosa. The multiple biopsies obtained from the antrum showed intestinal metaplasia and chronic gastritis with H.plylori positivity. Conclusion: Gastric xanthalesmas are asymptomatic benign and incidental endoscopic fi ndings. Even though they can be found in every part of Gastrointestinal tract from esophagus to colon, they are frequently observed in stomach. They are usually associated with chronic gastritis, Helicobacter pylori infection and intestinal metaplasia. Although the clinical signifi cance is unclear, gastric xanthalesmas are important lesions and biopsies should always be performed because they are frequently confused with malignant lesions.
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( Kevser Kutlu Tatar ),( Sibel Serin ),( Ece Yigit Taskin ),( Betul Ayaz ),( Sema Ucak Basat ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Endogenous endophtalmitis (EE), a sight-threating emergency,has been reported as the 2-8% of all endophthalmitis cases. EE is most often associated with a diagnosed underlying medical condition, including DM, liver disease, cardiac disease, malignancy, in-dwelling catheters and intravenous drug abuse (IVDU). A woman, 69 year-old, diagnosed with EE was followed up in the ophthalmology clinic for vitrectomy, consulted due to abdominal pain, pyuria and high levels of cholestasis enzymes. The patient had DM, hypertension, and ischemic heart disease for the last decade and severe heart failure for the last month. She had femoral catheter for ultrafi ltration two weeks ago. She was transferred to the internal medicine clinic with the differential diagnosis of heart failure, acute cholecystitis and urinary tract infection. In the MRCP imaging following an abdominal US, a signal differentiation due to possible metastasis or abscess was identifi ed in the liver. Multiple calculus in the neck of the bile cyst and cystic duct, sludge in gallbladder, expansion in choledoch diameter and multiple calculus at the distal part of choledoch were detected. A bilobular and fi at contoured, 85x140mm lesion was found at the left adnexa. A third echocardiography in a month was performed for her recently diagnosed cardiac failure and 2/6 systolic murmur, which was detectable best from the mitral point. The last echocardiography showed %50 EF, intermediate-advanced mitral insufficiency and a mass-vegetation on mitral valve. TEE, performed afterwards, showed vegetation on mitral valve and the possibility of valve perforation. Due to the continuation of decompensation and total obstruction in circumfi ex artery seen on the coronary angiography, coronary bypass and vegetation removal operations were performed. In this case, we present a case which has almost all the etiological reasons together except IVDU and which was diagnosed as IE based upon the EE diagnosis.
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( Gulcin Gungor Olcum ),( Guven Koc ),( Fidan Canan Celik Yagan ),( Ece Yigit Taskin ),( Senem Ertilav ),( Hanife Serife Aktas ),( Sati Sena Yildiz ),( Demet Ataman Tasan ),( Fatih Akdogan ),( Sema Ba 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: RA is a chronic systemic disease manifest with multiple joint infi ammation. Vasculitis, heart, lung disease, extra-articular symptoms can also be present. TNF-a,IL-6 and mediators such as cytokines, have been shown to have an important role in this infi ammatory process. Anti-TNF drugs considered to be effective in preventing; RA,disability and joint destruction. CRP is one of the best indicators of infi ammation though, ESR is an indirect indicator of infi ammation and ESR levels affected by age, sex, status and anemia. ESR and CRP levels in patients with RA, disease activity and has been shown to correlate with radiographic fi ndings In this study, we aim to to show the correlation between ESR, CRP levels with disease activity in patients receiving anti-TNF alpha therapy. Methods: In this Retrospective study between January 2006 to March 2010 patients diagnosed with RA were evaluated in two groups. In the study group patients receiving at least one year of TNF-alpha were included where as in the control group patients only receiving DMARD were include. Only female patients were involved in both groups. There were 46 women in the study and 47 women in the control group. Disease severity and DAS 28 score was used to determine the disease activity. For statistical analysis Number Cruncher Statistical System 2007 & PASS 2008 Statistical Software (Utah,USA) was used. Results: In patients receiving anti-TNF alpha therapy DAS 28 scores showed statisticallysignifi cant correlation with the ESR. A statistically signifi cance between DAS 28 and CRP were not found. In control group with only DMARD treatment, the DAS 28.
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