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수종 한약 처방 전탕액(煎湯液)의 허피즈바이러스에 대한 효능 검색
임성우,Lim, Seong-Woo 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.2
Objective : In order to find antiviral compounds against Herpes simplex virus type I(HSV-1) and II(HSV-2) from herb medicines, a convenient virus-induced cytopathic effect(CPE) inhibition assay was introduced. Methods : Fourteen purchased herbal medicines, and their toxicity of infected cell and anti-viral activities were evaluated. Among them, the major part of herbal medicines showed cell stability compared with the contrast. Results : Cytotoxic concentration (CC) of the $H_2O$ extracts of Hyongbangpaedoksan against HSV-1 and HSV-2 was 181.12. This is high level cytotoxic concentration compared with the contrast. Therefore, we assumed that the high level cytotoxic concentration of herbal medicine play a major role in improvement of antiviral activity at the first infective cell. But antiviral effect was unable to figure out for selective index(Sl)=CC50/EC50. The other herbal medicines were unable to showed potent anti-HSV activity. Conclusions : The antiviral activation using herbs in this thesis have unlimited objects, to select research object will help to show the direction of antiviral drug development that have less side effect and more excellent efficiency.
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임성우 영남대학교 인문과학연구소 2014 人文硏究 Vol.- No.71
‘독일의’ 또는 ‘독일어’의 의미를 가진 Deutsch의 형성과정을 보면 이는 단순히 한 민족의 언어나 국가명으로 발전한 것이 아님을알 수 있다. 도이치는 언어명, 민족명, 나라명이였으며, 심지어 18세기 이후부터는 문화 개념으로 자리 잡게 되었다. 이러한 도이치용어의 변천은 독일이 처했던 역사적 상황과 더불어 언어변천과도관련이 있다. 다른 유럽의 언어들과 마찬가지로 독일어는 라틴어,그리스어, 불어 등 서유럽의 언어들과의 다양한 관계 속에서 발전과 변화를 거듭해 왔다. 최근에는 세계화 경향 속에서 독일어에도 영어화 현상이 두드러지게 나타나고 있다. ‘뎅글리쉬’라는 독일식영어 표현들이 늘어나면서 우려의 목소리도 적지 않게 들린다. 그럼에도 불구하고 지금까지 독일어의 변화 과정을 보면 외래어와의접촉을 통해서 발전해 왔다는 사실을 잊어서는 안 된다. 물론 전세계적으로, 특히 유럽에서 ‘링구아 프랑카’의 지위를 영어가 담당하게 됨으로써 불어뿐만 아니라 독일어의 위상이 날로 추락하고있는 것이 사실이다. 하지만 세계화 시대에 지구촌 공용어로서 영어의 지위를 인정한다면 독일이 지리적, 문화적으로 속한 중부유럽 및 동유럽 국가들에서는 독일어의 위상이 상당히 높음을 알 수있다. 최근 유럽연합의 동유럽으로의 확대정책에서 나타나는 독일의 역할을 감안해 보면 새롭게 부상할 독일어의 위상도 어느 정도짐작할 수 있다. 나아가 향후 독일어가 서유럽과 중동부유럽 사이의 차이를 극복하고 ‘하나의 유럽’으로 심화하는 데 언어문화적 매개 역할을 할 것인지 주목해 볼 필요가 있다.
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A Single-Stage 12-Times Frequency Multiplier for a 5G Frequency Synthesizer
임성우,남규현,박준석 한국전자파학회 2022 Journal of Electromagnetic Engineering and Science Vol.22 No.3
This paper presents a single-stage 12-times frequency multiplier composed of an invented harmonic generator (HG) and a modified cascode buffer. The reliable output frequency band is guaranteed from 16 GHz to 28 GHz (54.5% frequency range). The whole band is divided to 256 subsidiary frequency bands by applying 8-bit digitally controlled capacitor banks of LC (inductor and capacitor)-tuned output. The invented HG architecture is based on a double-balanced mixer, but the bottom and top differential pairs are appropriately biased to generate the required turn-on time, , for obtaining the more dominant desired 12th harmonic. In addition, to reduce power consumption and conversion gain variation for the target frequency band, a negative-gm differential pair is added to the HG core in parallel to enhance the equivalent parasitic resistance, which is directly proportional to the HG gain. Newly created automatic constant amplitude control is able to keep the HG amplitude output constant as well as keep it from oscillating. Further desired harmonic amplification and unwanted suppression can be achieved by the proposed cascode buffer. The proposed 12-times multiplier is fabricated on a 65-nm CMOS (complementary metal-oxide-semiconductor) process and successfully tested. Chip die size is 0.4 mm2, and power consumption is only 4 mW.
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전전역의 특징과 기능에 관한 연구-메타의사소통적 기능 ‘수정’을 예로 들며
임성우 한국독어독문학회 2005 獨逸文學 Vol.104 No.-
Bei der Beschäftigung mit dem Vorvorfeld geht es darum, ein syntaktisches Phänomen zu beschreiben, das eine topologische Position vor dem Vorfeld konstituiert. Es besteht die Möglichkeit, ein Element vor einen Satz zu stellen und dadurch bestimmte Funktionen zu erlangen. Diese Elemente, die scheinbar außerhalb der Satzkonstruktion stehen, können besondere Hinweise auf eine Situation oder Anrufe des Gesprächspartners sein. Damit wird der linearen Folge von Informationen ein Signal oder Kommentar vorgeschaltet, der in einer losen Verbindung zum eigentlichen Satz steht. Dies beeinflußt den Satzbau syntaktisch nicht, aber übernimmt eine semantische und strukturierende Funktion. Die wichtigen Funktionen der Vorvorfeld-Elementen finden sich im Bereich der Metakommunikation. Hier wird dem Sprecher eine Vielfalt von Möglichkeiten eröffnet, seine Argumentation zu strukturieren, und gleichzeitig dem Hörer Hilfestellung zum Verstehen gegeben. Der Entschluss, ein sprachliches Element (scheinbar) außerhalb des eingentlichen Satzverbandes zu stellen, kann somit als Verweis auf kommunikative Aspekte der Sprache gedeutet werden, um die Verständlichkeit bei den Zuhörern zu sichern.
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임성우,한상헌,이성진,유석주,신형식,유형근,Lim, Sung-Woo,Han, Sang-Heon,Lee, Seong-Jin,You, Suk-Joo,Shin, Hyung-Shik,You, Hyung-Keun 대한치주과학회 2003 Journal of Periodontal & Implant Science Vol.33 No.4
Nicotine is one of the major components of cigarette smoking which causes various systemic and local diseases to human body. The purpose of the present study was to investigate the effects of nicotine on bone mineralization in human fetal osteoblasts cell line(hFOB1). To compare the alkaline ph-osphatase(ALP) synthesis, hFOBl were cultured with DMEM/F-12 1:1 Mixture and 100 pg/ml, 1 ng/ml, 10 ng/ml, 100 ng/ml, 1 ${\mu}g$/ml, 10 ${\mu}g$/ml, 100 ${\mu}g$/ml of nicotine. And to compare the calcium accumulation, hFOB1 cultured for 23 days were quantified and photographed. ALP activity of hFOB1 exposed to nicotine was not significantly changed at a lower concentrations of nicotine, but was significantly decreased at a higher concentrations (10 ${\mu}g$/ml, 100 ${\mu}g$/ml) of nicotine (p<0.05). A quantified calcium acculation in hFOB1 was significantly decreased at 1,10, and 100${\mu}g$/ml of nicotine (p<0.05). Significantly decreased calcium deposition was observed at 1, 10, and 100${\mu}$/ml of nicotine. These results indicate that a higher concentration of nicotine show a negative effects on mineralization of hFOB1.
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