호산구 농포성 피부염 - 수장 족저를 침범한 -

이형순,최응호,이승헌,강원형 ( Hyung Soon Lee,Eung Ho Choi,Seung Hun Lee,Won Hyoung Kang ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.6

We report herein a case of eosinophilic pustular dematosis with involvement of palms and soles in a 17-year-old man. The patient showed typical clinical pictures with specific laboratory and histopathologic findings of eosinophilic pustular dermatiss, We agree with the previous reports of Orfanos and Sterry`s and Saruta and Nakamizo`s, and also we may suggest that it is necessary to use of another term for this disease instead of eosinophilic pustular folliculitis because the hair follicles are not found on the palms and soles.

농업의 환경가치와 평가기법

이형순,Lee Hyung Soon 한국관개배수위원회 2002 한국관개배수논문집 Vol.9 No.2

중복 증후군 - 중추신경계 침범이 동반된 예 -

이형순(Hyung Soon Lee),김승민(Seung Min Kim),김수찬(Soo Chan Kim) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.2

We describe a patient with overlap syndrome in whom systemic lupus erythematosus and scleroderma were combined. The patient expired due to severe central nervous system involvernent and pneumonia. Pertinent neuropsychiatric signs of the patient included generalied seizure, impairment of recent, memory, dysarthria, mental deterioration, Balints syndrome, right sided hemiparesis and right sided central type facial weakness. Hrain MRI and cerebral angiogram slowed cerebral vasculopathy. We suggest that a long-term follow-up is necessary for the confirmation of ciagnosis of a connective tissue disease, because the evolution, transition and overlapping features among the group of connective tissue diseases may commonly occur over time. (Kor J Dermatol 1994; 32(2): 347-351)

질점막에 발생한 국소성 피부 점액증

이형순(Hyung Soon Lee),안성구(Sung Ku Ahn),이승헌(Seung Hun Lee),차동수(Dong Su Cha) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.1

A solitary, asymptomatic lesion, clinically resembling a transpare it cyst, has been present for 4 months in the vaginal mucosa of a 43-year-old healthy woman. An xcisional biopsy revealed the lesion to be a focal accumulatition of hyaluronic acid replacing the collagen fibers and fibroblastic proliferation in the dermis consistant with cutaneous focal mucinosis. During the follow-up period for 3 months, no recurrence was observed. (Kor J Dermatol 1993; 31 (1): 114-117)

무증상의 부신 골수 지방종 1예

이형순(Hyung Soon Lee),최새별(Sae Byeol Choi),김경식(Kyung Sik Kim) 한국간담췌외과학회 2008 한국간담췌외과학회지 Vol.12 No.4

Adrenal myelolipoma is a rare benign, non-functioning tumor that is frequently discovered incidentally. We report here on a case of a 47-year-old woman with an incidentally found adrenal tumor. She was slightly obese and had been diagnosed with diabetes. Her blood sugar level was well-controlled with oral hypoglycemic agents. All the laboratory test results were within normal limits. The abdomen CT scan revealed a well-demarcated homogenous solid mass that was 9cm in diameter, and it consisted of fat tissues. The differential diagnosis for malignant tumors was necessary, so we performed complete surgical excision. The patient recovered well without any major complications. If the diagnosis of adrenal myelolipoma is definite, then regular follow-up of this type of patient is sufficient. However, as the differential diagnosis with malignant tumors is rather difficult and as spontaneous hemorrhage can persist in the giant myelolipomas that are greater than 10cm in diameter, performing complete surgical excision is inevitable.

선상 한공각화증과 판형 한공각화증이 공존한 예

이형순(Hyung Soon Lee),정준(Joon Chung),안성구(Sung Ku Ahn),이승헌(Seung Hun Lee) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.2

We report herein a case of the coexistence of linear and placue porokeratosis in a 20-year-old female patient. The patient showed the typical clinical picures of linear and plaque porokeratosis on the right wrist, dorsum of the hand, dorsolater; I aspect of the fingers and axilla, respectively. Histopathologically, these lesions showed the typical cornoid lamella. We tried to remove the lesions with 75 100% trichloroacctic acid but could not gain a sat.isfact.ory effect. (Kor J Dermatol 1992;30(2): 234-238)

난소적출과 에스트로젠 투여가 백서의 하악골 고조에 미치는 영향

이형순(Hyung-Soon Lee),홍성규(Sung-Gyu Hong),김정기(Jong-Ghee Kim) 대한치과교정학회 1999 대한치과교정학회지 Vol.29 No.1

본 실험은 폐경기 골다골증 여성의 교정치료에서 일어날 수 있는 하악골의 구조의 변화와 에스트로젠 투여 효과를 추정하기 위한 연구의 일환으로 난소를 적출한 군과 에스트로젠 투 여 및 비투여군으로 분류하고 미세방사선사진으로 하악골을 촬영하여 이의 골 면적을 측정 하고 조직 변화를 관찰하였다. 생후 4개월된 Sprauge-Dawley계 백서 50마리를 난소적출 (OVE)군, 난소적출후 에스트로젠 투여(OVE-EST)군, sham operation 시행후 에스트로젠 투여(EST)군으로 분류하여 각군을 수술후 5주, 6주, 7주째 희생시켜 하악골을 적출한 후 좌 측 하악골은 비탈회표본으로 제작하여 미세방사선사진을 통해 해면골을 관찰하고 면적을 측 정하였으며 우측 하악골은 탈회표본으로 제작하여 병리조직학적인 소견을 관찰하여 다음과 같은 결과를 얻었다. 1. 하악골의 전체골면적에 대한 피질골의 비율분석에서 OVE군, OVE-EST군, EST군 모두 에서 통계적으로 유의한 변화가 없었다. 2. OVE군은 대조군에 비해 5,6,7주째로 갈수록 골수강의 비율이 증가하였는데(P<0.05), 백 서의 난소제거가 하악골에서도 골소주를 소실시켜 골수강을 확장시켰다. 3. OVE-EST군은 5주째는 골수강의 비율이 약간 증가되어 있었으나 점차 감소하여서 7주 째에 유의하게 적었고(P<0.05), EST군은 6주째부터 골수강의 비율이 현저히 감소되었는데 (P<0.05), 에스트로젠이 골수강의 크기를 감소시키는 효과가 있음을 알 수 있었다. 4. 미세방사선사진과 병리조직학적 소견상 OVE군에서 골수강들의 크기가 확장되었고, 파골 세포들이 불규칙한 변연부에서 다수 관찰된 반면, OVE-EST군은 점점 치밀해지는 골소주 들로 골수강이 작아지는 양상을 나타냈고, EST군에서는 풍부하고 치밀한 골소주들로 골수 강들의 크기가 작아졌다. The purpose of this study was to evaluate the changes of cancellous and cortical bone and the effect of estrogen in ovariectomized rats. Fifty female rats, 250gm in body weight, were divided into three groups : ovariectomized group(OVE), ovariectomized and estrogen-injected group(OVE-EST), and sham operated and estrogen-injected group(EST), Bilateral ovariectomy was performed at the onset of the experiment. In OVE-EST group and EST group, estrogen was injected 50µg/kg B.W. every other days from 3 weeks after surgery to sacrifice Each five rats were sacrificed after 5, 6, 7 weeks. One side of mandibular body was radiographed with a soft x-ray apparatus (Hitex Co., Ltd., Japan). Thereafter the obtained microradiographs were used for the morphometric analysis using a Image analyzer. The morphometric analysis was performed for parameters such as total bone area, cortex bone area and medullary one area. The other side of the mandibular bone was decalcified and embedded in paraffin as using a general method. The specimens were sectioned and stained with Mallory´s anilline blue and observed light microscopically. The results were as follows. 1. In all groups, the proportion of cortex to total bone area was not significantly different. 2. In ovarietomized(OVE) group, the proportion of marrow cavity to medullary bone area increased significantly from 5 to 7 weeks(p<0.05). In ovariectomized and estrogen-injected (OVE-EST) group, it decreased significantly at 7 weeks, and in estrogen-injected(EST) group, it decreased significantly from 6 week(p<0.05). 3. Microradiogram and histopathologic findings revealed that marrow cavity was enlarged and osteoclasts were observed around irregular bone surface in OVE group. In OVE-EST group, the size of marrow cavity at 7 weeks was similar to that of control group, as dense trabecular bone increased from 5 to 7 weeks, marrow cavity decreased.

위장관 ; 응급 위장관 수술 후 조기 경장 섭취의 안전성

이형순 ( Hyung Soon Lee ),심홍진 ( Hong Jin Shim ),이호선 ( Ho Sun Lee ),이재길 ( Jae Gil Lee ),김경식 ( Kyung Sik Kim ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.6

Background/Aims: Postoperative early feeding has many advantages, and current guidelines recommend the early diet or enteral feeding after gastrointestinal surgery. However, there are controversies in emergency situation. The aim of this study was to assess the safety of early enteral feeding in patients underwent emergency gastrointestinal (GI) surgery. Methods: We reviewed the patients underwent emergency GI surgery by single surgeon from March 2008 to December 2010, retrospectively. The early feeding was defined when feeding was started within 72 hours after operation. Results: Fifty-three patients were enrolled. Men were 31, with mean 60.6 (±18.5) years old age. Thirty-three patients were treated in the intensive-care unit after operation. The most common cause of operation was bowel perforation, and followed by intestinal obstruction. Segmental resection with primary anastomosis of small bowel is the most common operation. Thirty-two of them started the diet within 48 hours postoperatively. Twenty-nine patients had post-operative complications. Wound complications were the most common, and followed by the abdominal pain, and ileus. Wound complications were developed in 18 patients, and the post-feeding abdominal pain was in 7 patients. Anastomotic leakage and intraabdominal abscess were developed in 2 patients, and 1 patient required reoperation to treat the anastomotic disruption. One patient developed pneumonia and sepsis, and resolved under conservative treatment. There was no mortality in these patients. Conclusions: Early enteral feeding may be safe in cases of emergency GI surgery. However, it may require further studies to confirm the safety and feasibility of the early feeding in emergency situations. (Korean J Gastroenterol 2011;58:318-322)

간세포암 근치적 절제 후 발생한 간외 재발암의 위험인자 분석

이형순(Hyung Soon Lee),최기홍(Gi Hong Choi),황호경(Ho Kyung Hwang),강창무(Chang Moo Kang),최진섭(Jin Sub Choi),이우정(Woo Jung Lee) 한국간담췌외과학회 2010 한국간담췌외과학회지 Vol.14 No.4

Purpose: A few studies have been reported on extrahepatic metastasis after curative resection for hepatocellular carcinoma (HCC). We investigated the patterns of extrahepatic recurrence and we identified the risk factors for extrahepatic recurrence after curative resection for HCC. Methods: We retrospectively reviewed 587 patients who underwent surgical resection with a curative aim from January 1998 to December 2007 in the Yonsei University Health Care System. Among the 571 patients, 291 (51.0%) patients developed recurrence. Sixty five patients initially presented with extrahaptic recurrence. The patients with extrahepatic recurrence were divided into Group A (peritoneal recurrence) and Group B (non-peritoneal extrahepatic recurrence). Results: Group A had higher rates of intraoperative bleeding>1,500 ml and perioperative transfusion too. On the multivariate analysis, perioperative transfusion, satellite nodule and the tumor size were the independent risk factors for Group A. The Edmondson-Steiner grade, satellite nodule and the tumor size were the independent risk factors for Group B. The 1, 3 and 5-year overall survival rates after curative resection for the patients with extrahepatic recurence were 83.1%, 48.9% and 27.4%, respectively. The recurrence patterns and treatment modalities did not affect the overall survival after treatment for extrahepatic recurrence. Conclusion: A perioperative transfusion was found to be a different risk factor for peritoneal recurrence, as compared to those risk factors for non-peritoneal extrahepatic recurrence. Therefore, efforts by physicians to decrease intraoperative bleeding may prevent peritoneal recurrence after performing curative resection for HCC.

이중경제의 발전 메카니즘과 상대적 빈곤감

이형순( Hyung Soon Lee ) 한국경제학회 1985 經濟學硏究 Vol.33 No.1