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      • KCI등재

        Micronucleus Test of PolycanTM, β-Glucan Originatedfrom Aureobasidium, in Bone Marrow Cells of Male ICR Mice

        이형식,Hyung-Rae Cho,Kun-Ju Yang,Seung-Bae Moon,Bok-Ryeon Park,Hyun-Dong Shin,Hee-Jeong Jang,Lin-Su Kim,구세광 한국독성학회 2008 Toxicological Research Vol.24 No.1

        In this research the genotoxic effect of PolycanTM β-glucans originated from Aureobasidium pullulans SM-2001, was evaluated using the mouse micronucleus test. PolycanTM was administered once a day for 2 days by oral gavage to male ICR mice at doses of 1000, 500 and 250 mg/kg. Cyclophosphamide was used as a known genotoxic agent in a positive control group. The appearance of a micronucleus is used as an index for genotoxic potential. The results obtained indicated that Polycan TM shows no genotoxicity effect up to 1000 mg/kg dosing levels. In addition, it is also considered that there were no problems from cytotoxicity of PolycanTM tested in this study because the polychromatic erythrocyte ratio was detected as > 0.47 in all tested groups.

      • KCI등재
      • KCI등재
      • KCI등재

        정우회 국회의원 모리야 에이후(守屋榮夫)와 조선사회

        이형식 서울대학교 인문학연구원 2022 人文論叢 Vol.79 No.4

        Moriya Eihu exerted very strong power as the ‘doorknob power’ of the governor of Chosen during his term of office in Chosen, and continued to have an influence on Chosen with the ‘personal connections of the Governor-General of Chosen’ and those of the northeast area remaining in Japan as his background, even after he had left Chosen in 1924. Even after he became a member of House of Representatives, he raised funds for the war and rallied its supporting forces by establishing a Chosen branch of Dainihonsyouwarenmei, his own political organization. Using his ‘personal connections with Chosen people’ as a former lawyer, he took charge of big cases in Chosen, and got deeply involved in Chosen society and pending issues of Chosen by playing a role of window of the colonial lobby between Japanese in Chosen and influential people of Chosen. In this paper, the cases that Moriy was concerned with in his Jungwoohoe days, such as the case of Chosen industry, the establishment of Hamheung hydroelectricity, the Chosen civil engineering collusion case, and the matter of accepting Najin land, were used to examine the ways in which colonial politics operated. As a former colonial officer, Moriy made trials of the Chosen industry case, the Chosen civil engineering collusion case and others advantageous to his clients by contacting judges in advance or by mobilizing the Chosen governor, the prime minister, and the first political party, Jeongwoohoe, during the trials. Through his defense in the Akutsu trial where he turned away from the Chosen people whose land had been taken away, he not only earned a reputation as a lawyer, but also could finance his office as a member of House of Representatives. He raised funds by speaking for the influential Japanese in Chosen. In addition, he was also actively involved in the business of interest including the establishment of Hamheung hydroelectricity or the matter of accepting Najin land. In this process, he contacted the Japanese Government-General of Chosen, Mantetsu, local governments and others and lobbied them widely. His ‘colonial lobby’ for the establishment of Hamheung hydroelectricity can be said to be the typical case of ‘colonial development’ through ‘the corrupt relationship among government, business and offices' although it was dashed because of local residents’ fierce opposition. 모리야는 조선 재임 시절에는 조선 총독의 ‘문고리 권력’으로 막강한 권력을 행사했고, 1924년 조선을 떠났어도 조선에 남아 있던 ‘내무성 인맥’과 동북지역 인맥을 배경으로 조선에 영향력을 미쳤다. 중의원 의원이 되고 나서도 자신의 정치단체인 대일본소화연맹의 조선지부를 설치하여 정치자금을 조달하고 지지세력을 규합하는 데 이용하였다. 모리야는 전관 변호사로서 자신의 ‘조선인맥’을 이용하여 조선에서 굵직한 사건을맡았고 재조일본인과 조선인 유력자들의 식민지 로비(colonial lobby)의 창구 역할을 수행하는 등 조선사회와 조선 현안에 깊숙이 관여하였다. 본 논문에서는 정우회 시절 모리야가 관여한 조선산업사건, 함흥수력전기 설립, 조선토목담합사건, 나진토지수용문제 등을 사례로 식민지 정치가 작동하는 방식을 구명해 보았다. 모리야는 전관 변호사로서 재판 중에 재판관들과 사전에 접촉하거나 조선총독, 총리, 제1당인 정우회를 동원하여 조선산업사건, 조선토목담합사건 등의 재판을 의뢰자에게유리하게 이끌었다. 토지를 갈취당한 조선인들을 외면한 아쿠쓰 재판 변론을 통해서 변호사로서의 명성을 얻었을 뿐 아니라 중의원 의원 사무실 유지비도 마련할 수 있었다. 재조일본인 유력자의 이해를 대변하면서 이들로부터 정치자금을 조달했던 것이다. 한편, 함흥수력전기 설립이나 나진지토지수용문제 등와 같은 조선 이권사업에도 적극적으로 개입하였다. 이 과정에서 조선총독부, 만철, 지방정부 등과 접촉하여 광범위한 로비를 벌였다. 비록 지역 주민들의 격렬한 반대로 좌절되었지만 함흥수력전기 설립을 위한 모리야의 ‘식민지 로비’는 ‘정경관(政經官) 유착’을 통한 ‘식민지 개발’의 전형적인 사례라고 볼 수 있다.

      • KCI등재
      • SCOPUSKCI등재

        Radiation Therapy in Carcinoma of the Vulva A Review of Fifteen Patients

        이형식,오원용,서창옥,김귀언,박찬규,Lee H. S.,Oh W. Y.,Suh C. O.,Kim G. E.,Park C. K. The Korean Society for Radiation Oncology 1985 Radiation Oncology Journal Vol.3 No.1

        외음부에서 발생하는 악성종양은 부인과 영역의 악성종양 중에서는 드물게 발생하는 것으로 알려져 있으며 치료에 있어서도 수술 또는 방사선치료 단독의 경우보다는 수술 후 보조적으로 방사선 치료를 시행하는 것이 더 효과적이고 치료율도 높은 것으로 알려져 있다. 이에 1971년 1월부터 1985년 4월 사이에 연세대학교 의과대학 치료방사선과에서 외음부 악성 종양으로 진단되어 방사선 치료를 받았던 15예에 대하여 후향성 분석을 시행한 바 다음과 같은 결과를 얻었기에 보고하는 바이다. 1. 15예의 외음부 종양 환자 중 4예는 수술요법 시행 후 보조적요법의 방사선 치료를 받았으며, 1예는 수술전 방사선 치료를 받았고, 나머지 10예는 근치적 목적의 방사선 치료를 받았다. 2. 방사선치료만을 시행한 군과 방사선치료 및 수술요법을 병행한 군과의 국소제어율을 비교하여 본 결과, 전 15예의 국소제어율은 $53\%(8/15)$였으며, 단지 방사선 치료만을 시행한 군에서는 $40\%$(4/10), 방사선 치료 및 수술요법을 병행한 군에서는 $80\%(4/5)$의 국소제어율을 보였다. 3. 치료 실패율은(국소적 잔존+국소재발 또는 원격전이) 단지 방사선 치료만을 시행한 군에서는 $70\%(7/10)$, 수술 후 방사선 치료를 시행한 군에서는$40\%(2/5)$의 성적을 보였으며, 치료실패 호발부위는 원발병소(외음부)였다. This study analyzes fifteen patients who underwent a course of radiation therpy for their vulva cancer in the Department of Radiation Oncology, College of Medicine, Yonsei University from January, 1971 to April, 1985. Four patients had initial surgery for their vulva cancer and were subsequently treated by a course of adjuvant radiation therapy. Eleven patients were given radiation therapy as the initial course of therapy, and one of these was in adjuvant setting before radical surgery. Treatment in each instance was individuilzed and usually consisted of some components of external beam, brachytherapy, and/or electron beam therapy. Primary local control rate in all cases was $53\%(8/15),\;40\%(4/10)$ in the radiation therapy alone group and $80\%(4/5)$ in the radiation therapy combined with surgery group. Treatment failures were noted in 7/10 in the radiation therapy alone group and 2/5 in the radiation therapy combined with surgery group. The most common failure site was primary site failure(vulva).

      • KCI등재
      • KCI등재

        1980년대 할리우드 영화에 나타난 가족: <위험한 정사> 페미니즘 시각으로 다시 읽기

        이형식 문학과영상학회 2008 문학과영상 Vol.9 No.3

        The 1980s was a turning point in American history in that the rise of neoconservatism attempted to restore the terrain of the establishment which was lost to the challenges of civil rights movement, feminist movement, and counterculture movement in the previous decades. The so-called “backlash” trend was most conspicuous in the representation of women in mass media. The phenomenal success of Fatal Attraction and the heated response of the audience to the film reflect the suppressed anger of the conservatives who had been forced to relinquish their rights and status to women. Originally a moral tale about a man who commits adultery and pays the penalty, the screenplay had to be revised several times to cater to the taste of the producers who wanted to portray the single professional woman negatively. Consequently, the narrative structure and various cinematographic devices were tailored in order to delineate the Other woman who seduces the male character as a psychopath. In contrast, his wife is portrayed as an angel who devotes her time to such domestic duties as supporting her husband and taking care of their daughter. Therefore, this film turned out to be a morality play about a battle between the good woman and the bad woman. This paper aims to employ “reading against the grain” strategy, drawing on Laura Mulvey’s theory on visual pleasure in narrative cinema. Mulvey suggests that there are two avenues of escape to disavow the castration threat which female sexuality poses in the movies. One of them is voyeurism which provides audience with the pleasure of “ascertaining guilt, asserting control, and subjecting the guilty person through punishment or forgiveness.” In Hollywood movies, the male characters as bearer of the look usually become an active agent who forwards the story and make things happen. In this film, however, it is Alex who initiates the affair and propels the story forward with her powerful gaze and desire. Even though she is shot to death by Beth, her challenge against the patriarchy and law of the father is strong enough to disturb the equilibrium of the status quo. Therefore, the happy ending which shows the recovery of the family is a false one because the voice of independent women cannot be silenced even after Alex’s death. The 1980s was a turning point in American history in that the rise of neoconservatism attempted to restore the terrain of the establishment which was lost to the challenges of civil rights movement, feminist movement, and counterculture movement in the previous decades. The so-called “backlash” trend was most conspicuous in the representation of women in mass media. The phenomenal success of Fatal Attraction and the heated response of the audience to the film reflect the suppressed anger of the conservatives who had been forced to relinquish their rights and status to women. Originally a moral tale about a man who commits adultery and pays the penalty, the screenplay had to be revised several times to cater to the taste of the producers who wanted to portray the single professional woman negatively. Consequently, the narrative structure and various cinematographic devices were tailored in order to delineate the Other woman who seduces the male character as a psychopath. In contrast, his wife is portrayed as an angel who devotes her time to such domestic duties as supporting her husband and taking care of their daughter. Therefore, this film turned out to be a morality play about a battle between the good woman and the bad woman. This paper aims to employ “reading against the grain” strategy, drawing on Laura Mulvey’s theory on visual pleasure in narrative cinema. Mulvey suggests that there are two avenues of escape to disavow the castration threat which female sexuality poses in the movies. One of them is voyeurism which provides audience with the pleasure of “ascertaining guilt, asserting control, and subjecting the guilty person through punishment or forgiveness.” In Hollywood movies, the male characters as bearer of the look usually become an active agent who forwards the story and make things happen. In this film, however, it is Alex who initiates the affair and propels the story forward with her powerful gaze and desire. Even though she is shot to death by Beth, her challenge against the patriarchy and law of the father is strong enough to disturb the equilibrium of the status quo. Therefore, the happy ending which shows the recovery of the family is a false one because the voice of independent women cannot be silenced even after Alex’s death.

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