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      • KCI등재

        백색토끼에서 수술 현미경에 노출 후 망막의 변화

        이정규,김호영,조호균,Jeong Kyu Lee,Ho Young Kim,Ho Kyun Cho 대한안과학회 2011 대한안과학회지 Vol.52 No.5

        Purpose: This study was performed to investigate the potential damage to white rabbit retinas caused by an operating microscope light. Methods: A total of 18 white rabbits were exposed to the light of an operating microscope for 60 minutes. Fundus examination, fluorescein angiography (FAG), and electroretinogram (ERG) were performed before exposure and 1 hr, 1 day, 7 days and 14 days afterward to allow for serial comparisons. Light and electron microscopic examinations were performed to evaluate the changes in the rabbit retinas over time. Results: Signs of retinal damage upon fundus examination and FAG were not found before or after exposure to the light of an operating microscopy. ERG, however, showed significant reduction in the dark-adapted rod response 1 hour after light exposure, and significant decline in the amplitude of the maximal combined response a- and b-wave 1 day after light exposure in the rabbit retinas. ERG findings returned to the pre-exposure level after 2 weeks. Ultrastructural injury to the photoreceptor outer segments and the retinal pigmented epithelium, observed using transmission electron microscopy, recovered to the pre-exposure state after 2 weeks. Conclusions: The risk of retinal damage should be considered as an early result of exposure to the light of an operating microscope, even in normal retinal findings. J Korean Ophthalmol Soc 2011;52(5):603-609

      • KCI등재

        항녹내장 약제가 배양된 사람 결막상피세포에 미치는 영향

        이정규,류양환,Jeong Kyu Lee,Yang Hwan Ryu 대한안과학회 2006 대한안과학회지 Vol.47 No.11

        Purpose: To investigate the toxicity of a short-term application of timolol maleate, dorzolamide, and benzalkonium chloride (BAC) on human conjunctival epithelial cells in vitro. Methods: Chang‘s conjunctival epithelial cell line was treated for 5 min, 15 min, 30 min, and 60 min with various concentrations of timolol, dorzloamide, or BAC, and then examined 4 hrs or 24 hrs later. Cell viabilities were assessed by MTT assay. The expressions of various cytokines by timolol maleate, dorzolamide, and BAC treatment in human conjunctival epithelial cells were evaluated using ELISPOT. Results: BAC significantly decreased survival of conjunctival epithelial cells in a dose and time dependent manner compared with timolol and dorzolamide. Inflammatory cytokines, IL-6 and IL-8, were highly expressed in conjunctival epithelial cells treated with timolol, dorzolamide, and BAC. Conclusions: The present study suggests that increased expression of inflammatory markers, IL-6 and IL-8 might explain the ocular surface disorder in patients receiving antiglaucoma medication.

      • KCI우수등재

        교각에 의한 하상세굴에 관한 실험적 연구

        이정규,정동원,이창해,육운수,Lee, Jong Kyu,Jeong, Dong Won,Lee, Chang Hae,Yook, Woon Soo 대한토목학회 1994 대한토목학회논문집 Vol.14 No.6

        The results of laboratory experiments on the clear-water scour of cohesionless bed sediment for three types of pier shape were presented. According to the experimental data, the local scouring around the pier was initiated at $V/V_c=0.4{\sim}0.5$ and $Fr_p{\fallingdotseq}0.2$, and the relative local scour depths linearly increased with respect to the velocity ratio and the pier Froude number. The relative scour depth had the linear relationship with ${\tau}_r$ for ${\tau}_r$ < $10^{-4}$, but it tends to become constant for ${\tau}_r$ > $10^{-4}$, irrespective of ${\tau}_r$. And also the relative scour depths showed the close relationship with both the geometric standard deviation and the pier shape. 본 연구에서는 3가지 교각형상에 대하여 국부적 정지상세굴에 대한 실험결과를 분석하였다. 실험결과에 의하면 교각의 세굴은 $V/V_c=0.4{\sim}0.5$, $Fr_p{\fallingdotseq}0.2$일 때 시작되었고 상대세굴심은 유속비와 교각푸르드수와의 관계에서 선형적으로 증가하였다. 또한 상대세굴심은 ${\tau}_r$ < $10^{-4}$일 때는 선형적으로 증가하지만 ${\tau}_r$ > $10^{-4}$이 되면 일정해지는 경향을 가지며 모래의 기하표준편차(${\sigma}_g$)와 교각형상과도 깊은 관계가 있었다.

      • KCI등재

        NCS 기반 토양환경분야 국가기술자격 실기시험 평가방법에 관한 연구

        이정규,배재근,Lee, Jeong-Kyu,Phae, Chae-gun 한국지하수토양환경학회 2017 지하수토양환경 Vol.22 No.5

        Human Resources Development of Korea has been practicing performance evaluation for occupational qualification licences in environmental sectors that include water, air, and wastes management, but not soil. The purpose of the study was to improve overall quality of the national qualification test in the soil sector to better train applicants based on National Competency Standards (NCS), which is designed to emphasize site-specific conditions and knowledge. This study systematically analysed the current licence test in the soil sector with respect to qualification units, performance criteria, knowledge, techniques, and attitude as described in NCS. Furthermore, test evaluation was conducted to examine the validity of the revised licence test. The test results indicated the revised test method would bring positive outcomes to the related industry. Upon the reviews and amendments by the field experts, the result of this study could serve as a framework to the development of more robust and reliable licence test.

      • KCI등재

        詩ㆍ文에 나타난 李萬敷의 歷史認識

        이정규(Jeong-kyu Lee) 어문연구학회 2007 어문연구 Vol.54 No.-

          This thesis is aimed at examining the ancient history of our country, which Siksan Man-boo Lee had cognizance of. Prior to examining Siksan"s recognition of history, the researcher first paid attention to the consciousness of "making things valuable" which is thought to have affected the foundation for recognition of history. On the assumption that the real meaning of "making things valuable" may differ case by case, the researcher tried to make it clear that, overriding the assertion that Chosen succeeded China, Siksan"s consciousness of "making things valuable" expressed the culture of Chosen"s superiority, rather than none inferiority, to that of China. And, the researcher clarified that this point laid the foundation for Siksan"s having recognition of independent history. The peculiarity of the culture of home country is emphasized and the superiority of our culture is asserted everywhere in the writings scattered in a collection of Siksan"s works, And this confirmed that Chinese ethnic group and barbarians of the circumference are not distinguished by the race or location of a country, but by the culture of a country.<BR>  Subsequently, the researcher examined the recognition of history of our country in ancient times descending from Tangun time, by noting Siksan"s independent national consciousness that Chosen is an independent country as he deviates from the traditional viewpoint of Chinese ethnic group and barbarians of the circumference. He emphasized the existence of Tangun Chosen, extended the upper limit of our history by valuing highly the fact that Chosen was enlightened by Gija"s moving east, and noticed that thereby the pride of national culture was distinguished. But, he removed Wiman Chosen from our history, and did not considered our history discontinued by the outside power by determining the location of Hansagun to be above the Han River. Moreover, he showed dual recognition of history by establishing both the historical current of Tangun-Buyeo-Kokuryeo-Baekje and the other historical current of Tangun-Kija-Mahan.<BR>  Siksan attempted historical investigation of geography several times based upon what he saw and heard from his own travels, and went on to form his own historical viewpoint based upon the knowledge of ancient history he acquired from a variety of history books.

      • Barcelona Pavilion의 건축 분석

        이정규,Lee, Jeong-Kyu 배재대학교 공학연구소 1997 공학논문집 Vol.2 No.1

        이 논문에서 미스 반 데 로에의 바르셀로나 파빌리온의 건축적 특성을 분석하였다. 건축이 설계된 배경과 배치, 공간, 형태, 구조와 미학적 요소를 분석하였고, 같은 시기의 두 작품과 비교하였으며, 기존의 평가와 해석을 연구하였다. 그 결과 바르셀로나 파빌리온은 모든 근대건축 요소들이, 창작을 피워내는 상상력의 도가니 속에 함께 녹아들어 있음을 알게되었다. The pupose of thesis is to analyze the architectural characteristics of Mies's Barcelona Pavilion. I analyzed the site, space, form, structure, aesthetic elements, compared it with two other buildings by him, and studied the evaluation and interpretation about the building. I cocluded that all of the modern architectural elements were fused in the crucible of Mies's imagination to produce an original work of art.

      • 무기체계 사이버 보안 정책 동향

        이정규(Lee Jeong Kyu) 한국정보보호학회 2018 情報保護學會誌 Vol.28 No.6

        무기체계를 대상으로 한 다양한 형태의 사이버 위협에 직면하고 있다. 실제 상대국을 대상으로 한 공격행위도 언론을 통해 발표되고 있다. 무기체계를 대상으로 한 사이버 공격은 실물 공격보다도 더 큰 위력을 발휘하기 때문에 이를 대비하기 위한 보안 검증 강화는 그 무엇보다도 중요하다고 할 수 있다. 본 고에서는 이러한 사이버 위협, 미국과 우리의 보안정책을 알아보고 문제점을 진단하여 현실적 개선방향을 제시하고자 한다.

      • KCI등재
      • KCI등재

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