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이경진 천년의시작 2010 (계간)시작 Vol.9 No.4

Site-Specific Labeling of Proteins Using Unnatural Amino Acids

이경진,강덕희,박희성 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.5

Labelign of a protein with a specific dye or tag at defined positions is a critical step in tracing the subtle behavior of the protein and assessing its cellular function. Over the last decade, many strategies have been developed to achieve selective labeling of proteins in living cells. In particular, the site-specific unnatural amino acid (UAA) incorporation technique has gained increasing attension since it enables attachment of various organic probes to a specific position of a protein in a more precise way. In this review, we describe how the UAA incorporation technique has expanded our ability to achieve site-specific labeling and visualization of target proteins for functional analyses in live cells.

보행자시설 유형 재정립을 위한 기초연구

이경진,윤정은,윤일수 대한교통학회 2022 대한교통학회 학술대회지 Vol.87 No.-

복부관리요법이 삶의 질 및 신체상(Body Image)에 미치는 영향 체외충격파요법과 수기요법을 중심으로

이경진,이지현,오수연 한국인체미용예술학회 2019 한국인체미용예술학회지 Vol.20 No.1

This study attempted to investigate the effects of extracorporeal shockwave therapy (ESWT) and manipulative therapy on aesthetic factors – obesity-related quality of life and body image. For this, the therapies were given a total of 12 times to 45 middle-aged women with abdominal obesity (BMI: 23kg/ ㎡ or higher, WHR: 0.80 or higher, waist circumference: 80cm or greater) aged 35-59 living in Busan and Gyeongnam. According to analysis using SPSS 20.0, compared to manipulative therapy, the ESWT improved the obesity-related quality of life (F=79.828, p<0.001) and had a positive influence on appearance evaluation (F=136.554, p<0.001), health evaluation (F=19.912, p<0.001), appearance orientation (F=57.377, p<0.001), fitness orientation F=5.527, p=0.023), health orientation (F=31.061, p<0.001), preoccupation with being overweight (F=68.407, p<0.001) and body area satisfaction (F=133.102, p<0.001). In fitness evaluation and self-classification weight, there were no differences between the two groups. In addition, test subjects were satisfied with the abdominal care and realized its necessity regardless of how high or low the obesity-related quality of life/body image was. It’s anticipated that the study results would be available as evidence-based effective data that has considered an aesthetic aspect referring to the pursuit of feminine beauty.

자녀양육 과정에서 아버지들이 갖는 원가족 경험의 의미

이경진,박영숙,김낙흥 한국유아교육ㆍ보육복지학회 2018 유아교육·보육복지연구 Vol.22 No.4

본 연구의 목적은 자녀양육 과정에서 아버지들이 갖는 원가족 경험의 의미를 살펴보기 위한 것이다. 이를 위해 영아부터 성인까지의 자녀가 있는 30-50대 아버지 9명을 목적 표집하여 개별 심층면담을 통하여 자료를 수집하였다. 수집된 자료를 Colaizzi(1978)가 사용한 분석 방법을 활용하여 분석한 결과 4개의 범주와 10개의 하위범주로 분류하였다. 연구결과 첫째, ‘원가족 아버지를 통해 아버지상을 정의하다’에서는 전형적인 아버지상의 전이, 새로운 아버지상의 추구로 나타났다. 둘째, ‘원가족 아버지의 모습을 그대로 닮아가다’에서는 유일한 아버지 모델의 굴레, 자녀양육을 위한 참고서로 나타났다. 셋째, ‘원가족 아버지라는 산을 넘어가다’에서는 아버지를 객관적으로 바라보기, 내 안에 있는 아버지 깨닫기, 원가족으로부터 분리되어 아내와 하나 되기로 나타났다. 넷째, ‘원가족 아버지와의 관계를 다시 만들어가다’에서는 뒤늦게 깨달은 아버지의 사랑, 조금씩 풀려가는 아버지에 대한 원망, 자녀를 매개로 한 아버지와의 관계 회복으로 나타났다. 이러한 연구결과는 보다 긍정적인 자녀양육을 위해선, 아버지가 자신의 모습을 스스로 고찰하여 원가족과 관련된 그림자를 인식하고 원가족으로부터 분화하는 기회를 가짐으로써 원가족에 대한 부정적인 감정을 해소하고 자신을 좀 더 이해하려는 노력이 필요함을 시사한다. The purpose of this study is to examine the meaning of the original family experience of fathers in child rearing. For this reason, we collected nine fathers from 30 to 50 who have children from infants to adults and gathered materials through individual deep interviews. The collected data were analyzed by Colaizzi(1978)' method and classified into four categories and ten sub-categories. The results of this study are as follows: First, 'defining father's image through the original family father' showed 'a typical father's metastasis' and 'a new father's image pursuit'. Second, 'looks like the original family father' is 'bridle of the only father model' and 'a reference book for parenting'. Third, in 'crossing the mountain as the original family father', it appeared that 'observing the father objectively', 'realizing my father in me', and 'being separated from the original family and becoming oneness with the wife'. Fourth, in 'making a new relationship with the original family father', 'the father's love realized late', 'the resentment of the father gradually loosened', and 'the restoration of the relationship with the father through the child'. The results of this study suggest that for more positive parenting, it is possible to recognize the shadows related to the original family and to differentiate them from the original family by examining their own figure to solve the negative feelings about the original family and to understand themselves more suggesting that efforts are needed.

자색고구마 유산균 발효 음료 제조

이경진,배재오,박정섭,류숙희 한국식품영양과학회 2011 한국식품영양과학회 학술대회발표집 Vol.2011 No.10

Evaluation of dental status using a questionnaire before administration of general anesthesia for the prevention of dental injuries

이경진,김서율,박경미,양수진,김기덕,박원서 대한치과마취과학회 2023 Journal of Dental Anesthesia and Pain Medicine Vol.23 No.1

Background: Dental evaluation and protection are important for preventing traumatic dental injuries when patients are under general anesthesia. The objective of the present study was to develop a questionnaire based on dentition-related risk factors that could serve as a valuable tool for dental evaluation and documentation. Methods: We developed a questionnaire for dental evaluation before administration of general anesthesia, investigated the association between patient-and-dentist responses and mouthguard fabrication, and assessed response agreement between 100 patients. Results: Protective mouthguards were fabricated for 27 patients who were identified as having a high risk of dental injury. There was a strong association between dentists’ responses and mouthguard fabrication, depending on the general oral health status, use of ceramic prosthesis, presence of masticatory pain related to periodontal diseases, gingival edema, and implants (P < 0.05). Response agreement between patients and dentists for items related to dental pain, loss of dental pulp vitality, root canal therapy, dental trauma, aesthetic prosthesis, tooth mobility, and implant prosthesis was high (Cohen’s kappa coefficient κ ≥ 0.6). Conclusions: A high agreement was observed between patient-dentist responses and a strong association with mouthguard fabrication for items pertaining to ceramic prosthesis, masticatory pain, and dental implants. Patients with a “yes” response to these items are recommended to undergo a dental evaluation and use a dental protective device while under general anesthesia.

Suggesting Structure and Direction of a Library and Information Science Curriculum Applying Design Thinking Methods

이경진 한국문헌정보학회 2023 한국문헌정보학회지 Vol.57 No.1

In response to the changing needs of users and library services, there is a need to develop a library information science curriculum that reflects such change and to foster competent librarians. Recent studies abroad have emphasized the need for librarians who can apply design thinking methods which is a problem-solving methodology that expansively explores various alternatives and derives results, in response to recent changes and problems occurring in libraries. In this study, in order to understand how design thinking methods can be taught and to understand the perceptions of the students and librarians involved in the course, a case study is conducted of a class that applied design thinking methods and students and librarians have been interviewed who had experience participating in the class. By reflecting on the needs of students and librarians’, this study explored new directions of what forms courses can take for future librarians. Based on the results of the analysis, among the different characteristics of design thinking, the value of cooperation, problem-solving ability, flexibility and iteration of design characteristics was considered as the value of a class for LIS students and librarians where design thinking methods were applied. From the findings, the research suggests future directions of creating more structured courses that involve an element of design thinking.

PBL을 적용한 정신건강론 과목에서 예비유아교사의 경험 과정과 의미 탐색

이경진,조은지 한국어린이문학교육학회 2021 어린이문학교육연구 Vol.22 No.1

The purpose of this study was to analyze the meaning of operating mental health theory subjects with PBL for preservice early childhood teachers. Participants in the study were 25 preservice early childhood teachers and three professors and 3 human resources. As a process of PBL, teams drew up solutions to a two-stage dilemma, and presentations and evaluations were made. The collection of data took place over four months by taking recordings and collecting written data and field notes. Three categories and six subcategories were analyzed as the meaning of implementing the subject of PBL-applied mental health theory for preservice early childhood teachers. As a category of “Serious exploration of children’s mental health,” “Deeply empathy for children's mind” and “Actively exploring mental health knowledge” were derived. As a category of “The creation of a consensus on parenting and family connections for children’s mental health support,” “Understanding parents and the parenting environment of children” and “re-recognition of the importance of home and institutional linkage for children’s mental health support” were derived. As “building practical confidence in solving mental health problems that can be faced as teachers,” “looking at one's mental health as a prospective preservice early childhood teacher” and “building confidence in solving mental health problems for children through the process of exploring with the group” were derived. 본 연구의 목적은 예비유아교사를 대상으로 PBL을 적용한 정신건강론 과목 운영의 의미를 분석하는 것이다. 연구 참여자는 4년제 유아교육학과 2학년에 재학중인 예비유아교사 25명과 교수자 및 인적자원 3명이다. PBL의 과정으로서 팀별로 2단계 딜레마에 대해 해결안을 도출하였고, 발표 및 평가가 이루어졌다. 자료의 수집은 녹음 및 녹화와 서면자료 수집, 현장노트 기록으로 4개월 간 이루어졌다. 예비유아교사를 대상 PBL적용 정신건강론 과목 실행의 의미로서 3개의 범주와 6개의 하위 범주가 분석되었다. ‘영유아 정신건강에 대한 진지한 탐구’ 범주로서 ‘영유아의 입장에 대해 깊이 공감하기’와 ‘정신건강 지식을 적극적으로 탐구하기’가 도출되었다. ‘영유아 정신건강 지원을 위한 양육자 및 가정연계 공감대 형성’으로는 ‘영유아의 양육자와 양육환경에 대한 이해하기’와 ‘영유아 정신건강 지원을 위한 가정과 기관 연계의 중요성 재인식하기’가 도출되었다. ‘교사로서 직면할 수 있는 정신건강 문제해결에 대한 실천적 자신감 형성’으로 ‘예비유아교사로서 자신의 정신건강 바라보기’와 ‘조원과 함께 탐구하는 과정을 통해 영유아의 정신건강 문제 해결에 대한 자신감 다지기’가 나타났다.

두경부암 환자 방사선 치료 시 BinkieRT^TM(구강용 고정장치)에 대한 유용성 평가

이경진,손상준,임경달,김찬용,이제희,GyeongJin Lee,SangJun Son,GyeongDal Lim,ChanYong Kim,JeHee Lee 대한방사선치료학회 2022 대한방사선치료학회지 Vol.34 No.-

Purpose: The purpose of this study is to evaluate the effectiveness of oral positioning stent, the BinkieRT^TM in radiation treatment for head and neck cancer patients in terms of tongue positions reproducibility, tongue doses and material properties. Materials and Methods: 24 cases using BinkieRT^TM during radiation treatments were enrolled. The tongue was contoured on planning CT and CBCT images taken every 3 days during treatment, and then the DSC and center of tongue shift values were analyzed to evaluate the reproducibility of the tongue. The tongue dose was compared in terms of dose distribution when using BinkieRT^TM and different type of oral stents (mouthpiece, paraffin wax). Randomly selected respective 10 patients were measured tongue doses of initial treatment plan for nasal cavity and unilateral parotid cancer. Finally, In terms of material evaluation, HU and relative electron density were identified in RTPS. Results: As a result of DSC analysis, it was 0.8 ± 0.07, skewness -0.8, kurtosis 0.61, and 95% CI was 0.79~0.82. To analyze the deviation of the central tongue shift during the treatment period, a 95% confidence interval for shift in the LR, SI, and AP directions were indicated, and a one-sample t-test for 0, which is an ideal value in the deviation(n=144). As a result of the t-test, the mean and SD in the LR and SI directions were 0.01 ± 0.14 cm (p→.05), 0.03 ± 0.25 cm (p→.05), and -0.08 ± 0.25 cm (p ←.05) in the AP direction. In the case of unilateral parotid cancer patients, the Dmean to the tongue of patients using BinkieRT^TM was 16.92% ± 3.58% compared to the prescribed dose, and 23.99% ± 10.86% of patients with Paraffin Wax, indicating that the tongue dose was relatively lower when using BinkieRT^TM (p←.05). On the other hand, among nasal cavity cancer patients, the Dmean of tongue dose for patients who used BinkieRT^TM was 4.4% ± 5.6%, and for those who used mouthpiece, 5.9% ± 6.8%, but it was not statistically significant (p→.05). The relative electron density of Paraffin Wax, BinkieRT^TM and Putty is 0.94, 0.99, 1.26 and the mass density is 0.95, 0.99 and 1.32 (g/cc), Transmission Factor is 0.99, 0.98, 0.96 respectively. Conclusion: The result of the tongue DSC analysis over the treatment period was about 0.8 and Deviation of the center of tongue shifts were within 0.2 cm, the reproducibility was more likely excellent. In the case of unilateral head and neck cancer patients, it was found that the use of BinkieRT^TM rather than Paraffin Wax or Putty can reduce the unnecessary dose irradiated to the tongue. This study might be useful to understand of BinkieRT^TM's properties and advantages. And also it could be another considered option as oral stent to keep the reproducibility of tongue and reducing dose during head and neck radiation treatments.