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      • Trypsin inhibitor 결여大豆品種의 탐색 및 그의 遺傳育種學的 硏究 : Ⅱ. Kunitz 및 Bowman-Birk trypsin inhibitor의 정제 및 분리

        金秀一,이홍석 서울大學校 農科大學 1986 서울대농학연구지 Vol.11 No.1

        Crude Kunitz and Bowman-Birk soybean trypsin inhibitors were fractionated into three fractions by Sephadex G-75 gel filtration respestively. The Kunitz and Bowman-Birk trypsin inhibitors from Sephadex G-75 column chromatography were resolved into nine and eight fractions by DEAE-cellulose chromatography respectively. All the fractions except ninth fraction of Kunitz inhibitors revealed trypsin inhibiting actvities. Each fraction isolated was examined their polyacrylamide gel electrophoretic patterns with or without SDS. Among 10 main bands, five were appeared as trypsin inhibitors. Kunitz inhibitors differ from Bowman-Birk inhibitors in their electrophoretic patterns, showing band 3 and 4 as main bands instead of band 6,7,8 and 9 for Bowman-Birk trypsin inhibitors. The moleculer weight of Kunitz trypsin inhibitors was 22 Kdaltons while that of Bowman-Birk inhibitors was lower than 14 Kdaltons. In addition, Bowman-Birk type inhibits chymotrypsin twice as much as Kunitz type inhibitors.

      • KCI등재

        최근 10년간 국내의 봉독 관련 연구에 대한 고찰

        이홍석,이재동,고형균,Lee, Hong-seok,Lee, Jae-dong,Koh, Hyung-kyun 대한침구의학회 2003 대한침구의학회지 Vol.20 No.3

        Objective : to research the trend of the study related to Bee venom and o establish the hereafter direction for the study on Bee Venom therapy. Methods : We reviewed the domestic papers published last ten years(1992-2001). Results: 1.We have searched 53 papers in 7 journals and the pattern of study was as follow: the experimental studies were 33, the clinical studies were 10 and the reviewed studies were 10. 2. The experimental studies were 2 papers of analysis of Bee Venom, 3 papers of safety assessment, 1 paper on production of antibody against Bee Venom and 26 paper of safety assessment. 3. Bee Venom used in studies was made in Korea, China and U.S.A.. There were differences of component and effect according to the place of production. 4. There were the experimental studies of LD50 in mouse, acute toxicity, local irritation test, antigenicity and pyrogen test of Bee Venom. Conclusions : We need more studies of unification of term about Bee Venom, difference according to the place of production, clinical safety and effects.

      • 干拓地의 際鹽用水量 算定에 關한 硏究

        李洪石,具滋雄,李長春 전북대학교 농업과학기술연구소 1986 農大論文集 Vol.17 No.-

        In this laboratory study two different reclamation experiments(Rinsing and Leaching method with mixing gypsum and soil at the rate of 1.2ton/10a) were carried out to estimates water requirements for reclaiming salt-af footed soils. The results of the reclamation experiments were summarized as follows; 1. When the depth of water applied per unit depth of soil was 3.0 in Rinsing method, the fraction of sodium concentration remaining in soils was 16-25% and the fraction of total salt concentration remaining in soils was 25-35%. 2. When the depth of water leached per unit depth of soil was 0.30 in Leaching method, the fraction of sodium concentration remaining in soils was 14-15% and the fraction of total salt concentration remaining in soils was 35-37%. 3. The ESP value decreased to less than standard level 15% in Rinsing method when the depth of water applied per unit depth of soil was more than 2.4, and it decreased to less than 15% in Leaching method when the depth of water leached per unit depth of soil more than 0.15. 4. The ECe value decreased to less than standard level 4㎜hos/㎝ in Rinsing method when the depth of water applied per unit depth of soil was more than 2.7, and it decreased to less than 4㎜hos/㎝ in Leaching method when the depth of water leached per unit depth of soil was more than 0.27. 5. It is considered as a reasonable method that the water requirement for reclamation(depth of water applied or leached per unit depth of soil) is applied to be 3.0 in Rinsing method and 0.30 in Leaching method.

      • SCOPUSKCI등재
      • KCI등재

        근대 상해주재 일본총영사관경찰기구 연구

        이홍석,장흠 전북사학회 2022 전북사학 Vol.- No.66

        1872년 일본은 중국 상해공공조계지에 첫 번째 주중 영사기구인 총영사관 을 설치하였다. 1884년부터 일본교민을 ‘보호취체’ 한다는 핑계로 일본국내로 부터 상해총영사관에 외무성경찰을 파견하기 시작한 후, 1945년까지 선후로 상해총영사관 안팎에 경찰서·경찰부·파출소·파견소·분서 등 다양한 경찰 기관을 설치하였다. 상해총영사관경찰기관은 최대로 25개, 경찰 인원은 220명 에 달한 적도 있었다. 이들 경찰관의 존재와 활동은 아무런 법적 근거가 없 기에 모두 불법이다. 당초 상해총영사관경찰은 일본 교민들에 대한 ‘보호단 속’만 했지만 신해혁명 이후부터는 주로 중국 정세에 대한 정보활동을 하기 시작했다. 9.18사변 이후에는 상해총영사관에 중국대륙에서 최대의 정보기구 인 특고경찰과(제2과)를 설치하고 특고경찰로써 중국인들의 반일배일운동을 적극적으로 감시하고 취체하였으며 심지어 중국·조선의 반일인사를 공개적 으로 체포했으며 중국인들의 반일무장을 무자비하게 탄압하였다. 결과, 상해 일본총영사관경찰은 중국에서 수많은 침략죄행을 저질렀다. 총적으로 상해총 영사관경찰기구는 영국·미국 등 구미열강들의 주중영사관에 없는 특수한 침 략기구로서 근대일본의 중국침략에서 특수한 역할을 하였다. Japan set up its first consulate in China in 1872 in the Shanghai Public Concession.Since 1884, Japan has dispatched police officers to the Shanghai Consulate General under the pretext of protecting and banning overseas Chinese.Japan has set up various police agencies such as police stations, police departments, dispatch offices, police stations, branch offices, and the “Central Police Department” inside and outside the consulate. The Shanghai Consulate has a maximum of 25 police agencies and 220 police officers. As the establishment of these police agencies has no legal basis, their existence and their activities are null and void.Initially, the Shanghai consulate police only engaged in the “protection and ban” of Japanese overseas Chinese. Since the Revolution of 1999, he has been mainly engaged in intelligence activities on the Chinese political situation. In particular, after the September 18th Incident, the Japanese Consulate General in Shanghai set up the largest intelligence agency in mainland China, the “Extra High Police Section” (referred to as “Extra High Section”, externally known as “Second Section”). The “super high police” actively monitored and banned the resistance movement of the Chinese people, and publicly searched and arrested the anti-Japanese people in various countries with guns.These police officers have been present since the surrender of Japan in 1945, during which time they committed unforgivable crimes of aggression in China.

      • 문턱전류이상에서 구조 및 재료 변수들이 $\lambda$/4위상천이 DFB 레이저의 단일모드 이득차에 미치는 영향

        이홍석,김홍국,김부균,이병호 대한전자공학회 1999 電子工學會論文誌, D Vol.d36 No.3

        주입전류가 문턱전류 이상일 때 선폭증가계수, 구속계수, 내부손실과 레이저의 길이가 λ/4 위상천이 DFB레이저의 단일모드 이득차와 발진주파수의 변화에 미치는 영향에 대하여 체계적으로 연구하였다. 구속계수나 선폭증가계수와 구속계수의 곱으로 주어지는 변수보다 선폭증가계수가 단일모드 이득차 및 발진주파수에 미치는 영향이 크다. 내부손실이나 레이저 길이 각각의 값보다 내부손실과 레이저 길이의 곱으로 정의되는 정규화된 내부손실이 DFB 레이저의 단일모드 이득차 및 발진주파수의 변화에 미치는 영향이 크다. 정규화된 내부손실이 같은 경우에는 내부손실계수보다 레이저의 길이가 동작특성에 미치는 영향이 큼을 알 수 있었다. 또한 양자우물 레이저가 builk 레이저에 비하여 선폭증가계수가 작기 때문에 구속계수와 정규화된 내부손실 값의 변화에 따른 단일모드 이득차의 감소와 발진주파수의 변화가 작음을 보았다. Systematic studies for the effect of the linewidth enhancement factor, the confinement factor, the internal loss and the cavity length on the single mode gain difference and the frequency detuning are performed for $\lambda$/4 phase shifted DFB lasers above threshold. The above threshold characteristics are mainly determined by the linewidth enhancement factor, not by the confinement factor or the parameter defined by the product of the linewidth enhancement factor and the confinement factor. The normalized internal loss defined by the product of the internal loss and the cavity length mainly determines the above threshold characteristics compared to that of the internal loss or the cavity length alone. The effect of the cavity length on threshold characteristics is larger than that of the internal loss in the case of the same normalized internal loss. The above threshold characteristics of quantum well lasers are more resistant to the variations of the confinement factor and the normalized internal loss than those of bulk lasers due to the small linewidth enhancement factor.

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