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- 저자 : 沈鳳燮 (검색결과 454 건)
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Studies on Urinary Haptoglobin in Normal Person
심봉섭,홍경자,최홍락 생화학분자생물학회 1975 BMB Reports Vol.4 No.2
The excretion of haptoglobin component into the urine was investigated in the normal person. Urine was concentrated by ultrafiltration, and urine concentrate was tested with various antisera, and the urinary specific fast-migrating haptoglobin component was isolated by starch block electrophoresis, and the molecular weight was estimated by gel filtration technique. Urine contained fast-migrating haptoglobin component in addition to the intact haptoglobia. The fast component was always complexed with hemoglobin, and it contained both alpha- and beta-chains; however, it showed different conformational immunological reaction from intact serum Hp-Hb complex. From the estimation of molecular weight, it was concluded that the fast urinary haptoglobin component would be a half of the normal 1-1 Hp-H.b complex.
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