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황준일 ( Jun Eul Hwang ),우학 ( Hak Woo ),김상호 ( Sang Ho Kim ),이우석 ( Woo Seok Lee ),황재하 ( Jae Ha Hwang ),김정철 ( Jung Chul Kim ),조덕 ( Duck Cho ),박정진 ( Jeong Jin Park ),이신석 ( Shin Seok Lee ),박용욱 ( Yong Wook Pa 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.2
Necrotizing fasciitis is a life-threatening soft tissue infection involving skin, subcutaneous tissue, and superficial fascia. We report a case of necrotizing fasciitis that developed in a 76-year-old female patient taking low-dose methotrexate and prednisolone for rheumatoid arthritis (RA). A computed tomography scan of the neck during the initial work-up showed soft tissue swelling, loss of fat planes, and mild heterogeneous enhancement in the right lateral neck, suggesting cellulitis. The lesions were associated with skin necrosis and multiple bullae rapidly expanded to the right anterior chest in spite of empirical antibiotic therapy. Surgical debridement was immediately performed, and soft tissue biopsy from the lesions showed the pathologic finding consistent with necrotizing fasciitis. The skin wound defect was reconstructed by a flap operation with split-thickness skin graft. This case shows the development of necrotizing fasciitis in a elderly patient taking methotrexate and low-dose steroid for RA and highlights early recognition and prompt surgical debridement for successful management.
황준,정의식,Duk-Chul Hwang 한국정밀공학회 2005 International Journal of Precision Engineering and Vol.6 No.3
This paper presents the experimental results to verify the atomization characteristics and environmental impact of cutting fluid. Even though cutting fluid improves the productivity through the cooling and lubricating effects, environmental impact due to cutting fluid usage is also increased on factory shop floor. Cutting fluid's aerosol via atomization process can generate human health risk such as lung cancer and skin diseases. Experimental results show that the generated fine aerosol of which particle size less than 10 micron appears near working zone under typical operation conditions. The aerosol concentration also exceeds NIOSH regulations. This research can be provided as a basis of environmental impact analysis for environmental consciousness.
황준서(Joon Seo Hwang),유형곤(Hyeong Gon Yu) 대한검안학회 2012 Annals of optometry and contact lens Vol.11 No.1
목적: 한국인 망막색소변성 환자의 초진 시 시야장애를 평가하고자 한다. 대상과 방법: 망막색소변성 환자의 초진 시 시야, 시력장애의 분포와 유전양상에 따른 차이를 분석하였다. 결과: 총 400명의 환자의 유전양상은 상염색체우성 17.0%, 상염색체열성 11.0%, X-연관열성 3.5%, 단순형 68.0%였다. 잔존시야가 반경 50o 이상인 환자가 7.3%, 25∼50o가 10.8%, 10∼25o가 29.3%, 10o 미만(World Health Organization 분류: 심한 저시력)이 52.8%였다. 중심시력은 20/30 이상이 43.8%, 20/100∼20/30이 44.5%, 20/200∼20/100이 5.5%, 20/200 미만(심한 저시력)이 6.3%으로, 중심시력저하가 시야장애에 비해 경하였다. 유전양상에 따른 장애는 상염색체열성과 X-연관열성에서 심해, 반경 25o 이상의 잔존시야를 보이는 경우가 없었고, 20/30 이상인 시력을 가지는 비율도 낮았다(15.2%, 35.7%). 결론: 한국인 망막색소변성 환자는 초진 시 진행된 시야장애를 보이고, 시야장애가 중심시력저하보다 심하였다. 상염색체열성과 X-연관열성 환자에서 상염색체 우성과 단순형에 비해 더 진행된 시야장애를 나타내었다. Purpose: To evaluate visual field defect of Korean patients with retinitis pigmentosa (RP). Methods: A total of 400 patients with RP who were diagnosed within 3 years, 231 males and 169 females were included in this study. Data were collected including age, symptomatic disease duration, family history, visual acuity (VA), Goldmann visual field (VF) at the initial visit. Results: Determination of inheritance pattern revealed 17.0% autosomal dominant RP cases, 11.5% autosomal recessive (AR) RP, 3.5% X-linked recessive (XL) RP, and 68.0% simplex RP, indicating a relative small proportion of AR RP cases. The remaining visual filed was ≥50o (radius) in 7.3%, 25∼50o in 10.8%, 10∼25o in 29.3% and ≤10o in 52.8%. Visual acuity was ≥20/30 in 43.8%, 20/100∼20/30 in 44.5%, 20/200~20/100 in 5.5% and ≤20/200 in 6.3%. The functional acuity score of 83.3±17.2 was higher than the functional field score of 49.9±20.5. VA and VF defects were greater in AR RP and XL RP than in other types, the proportion of ≥20/30 VA was smaller and there was no patient who had VF greater than 25o. Conclusions: Korean RP patients had advanced visual field defect at the initial visit. VF defect was greater than VA loss and more severe in the patient with AR RP and XL RP.