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다발성 전이를 동반한 고령의 간세포암 환자에서 경동맥방사선색전술과 반복적 경동맥화학색전술로 간내암과 다발성 전이의 부분관해를 이룬 증례
황상연 ( Sang Youn Hwang ),이선미 ( Seon-mi Lee ),임정우 ( Jung Woo Im ),전기정 ( Ki Jeong Jeon ),안상부 ( Sang Bu Ahn ),박진영 ( Jin-young Park ) 대한간암학회 2018 대한간암학회지 Vol.18 No.2
The number of older adults with hepatocelluar carcinoma (HCC) has been increasing with longer life expectancy and earlier diagnosis and treatment. However, older patients have lesser function reserve of multiple organ systems, more disability rate. Therefore, the treatment of elderly HCC patients remains a challenge worldwide. Recently, studies suggests that the survival outcome of older patients may be comparable to that of younger patients and active treatment may achieve promising rates of local and systemic control in selected patients. Based on above suggestions, we herein offer our experience of a case achieved partial remission by sequential therapy of transarterial chemoembolization after transarterial radioemoblization in elderly HCC patient with multiple metastasis. Further study, maybe regarding a combination of locoregional and systemic treatment, is necessary on how to manage HCC in elderly patients. (J Liver Cancer 2018;18:151-156)
황정임(Jeong-Im Hwang),최윤지(Yoon-Ji Choi),최정신(Jung-Shin Choi) 한국농촌지도학회 2018 농촌지도와 개발 Vol.25 No.2
Farm succession is one of the m ost im portant events that substantially influence the viability of a farm business not only for a fam ily farm operation, but also for a farm industry as a w hole. This study aim s to analyze the factors w hich affect the probability of existence of a successor, using the nationw ide survey data. The probability of having a successor increases w ith the age of operator, the num ber of sons, the area under cultivation, organic farm ing, farm expansion plan, m ain crop and operator’s attitude tow ards farm succession. Also this study investigates the succession plans of fam ily farm s having a successor and land disposal plans of fam ily farm s w ithout a successor. 40% of farm s having a successor have only vague succession plans and 34.7% of farm s w ithout a successor have a plan to apportion their land am ong their children. Based on these results, this study suggests the necessity of planning for farm succession and successors’ agricultural training. In addition, m easures for preventing from land fragm entation are needed for realization of effective usage of agricultural land.
소라페닙 치료 실패 후 소라페닙과 Tegafur 병용요법을 통해 간세포암의 완전관해를 유도한 증례 1예
황상연 ( Sang Youn Hwang ),이선미 ( Seon-mi Lee ),임정우 ( Jung Woo Im ),전기정 ( Ki Jeong Jeon ),안상부 ( Sang Bu Ahn ),박진영 ( Jin-young Park ),최철원 ( Cheol-won Choi ),양광모 ( Kwang-mo Yang ) 대한간암학회 2017 대한간암학회지 Vol.17 No.1
Sorafenib is the only approved targeted agent as the first line systemic therapy for treatment of advanced hepatocellular carcinoma (HCC). However, the improvement of survival duration under 3 months is far from clinical satisfactory and most patients experience disease progression within 6 months after sorafenib therapy. Unfortunately, second line systemic therapy after treatment failure of sorafenib was not established and there were no clear guidelines for salvage treatment modalities. Recently, studies suggests that combination of sorafenib and single cytotoxic agent can be relatively effective and safe strategy that achieves promising rates of local and systemic control in advanced HCC patients. Based on above suggestions, we herein offer our experience of a case achieved complete remission by combination therapy of sorafenib and tegafur in the patient with progressed disease after sorafenib therapy. (J Liver Cancer 2017;17:88-93)
한부모가족 지원을 위한 네트워크 강화 방안에 관한 탐색적 연구
황정임(Jung-im, Hwang),이호택(Ho-taek, Lee),김유나(Yu-na, Kim) 한국여성정책연구원 2016 여성연구 Vol.91 No.2
본 연구는 한부모 가족지원을 목적으로 실시되는 대표적인 정책 사업인 취약·위기가족지원사업이 한부모 가족의 다양한 문제와 복합적인 서비스 수요에 부응할 수 있도록 네트워크 현황을 파악하고, 활성화 방안을 모색하는데 목적을 두었다. 이를 위해 취약·위기가족지원사업을 수행하는 건강가정지원센터 30개소 전수를 대상으로 네트워크 현황조사를 실시하였고, 이 가운에 조사에 응한 23개소의 자료를 토대로 분석을 실시하였다. 또한 네트워크 운영의 문제점과 개선방안을 심도 있게 모색하기 위해 전문가 및 현장관계가 15명을 대상으로 포커스그룹인터뷰를 실시하였다. 조사결과를 토대로 건강가정지원센터의 한부모 가족지원 네트워크 강화를 위해서는 전담 인력 및 조직 강화, 네트워크 역량강화 시스템 운영, 다양한 서비스 개발, 공공부문과의 네트워크 활성화, 연대활동 강화 노력이 필요함을 제시하였다. 본 연구는 최근 한부모 가족지원의 새로운 복지 전달체계로 자리매김하고 있는 건강가정지원센터의 한부모가족지원사업 네트워크 현황에 대한 기본적인 이해와 더불어 실천방향을 제시하였다는 점에서 의미를 지닌다. The purpose of this study is examine the current state and problems of networks to support single-parent families and present measures for operating networks to provide customized support and integrated services in response to policy demands for single-parent families. To examine current state of network, survey data collected from 23 centers that offering social services to single parent families was utilized. To figure out critical problems and improvement plan, we conducted focused group interviews with 15 researchers and people concerned. Based on the results of survey and FGI, following strategies were suggested : (1) to facilitate institutions’capabilities for networking, competencies for both staffs and organizations’ toward networking should be strengthened, (2) to meet diverse demands of single parent families, more supportive programs must be developed, and (3) building cooperative relationships with public sector is needed for intensify network system to improving supports for single parent families.
황정규(Jung gyu Hwang),심두보(Doobo Shim),임현정(Hyeon Jeong Im),박상기(Sang Ki Park),강은주(Eun-Ju Kang),조경환(Kyung hwan Cho),배성경(Seong Kyeong Bea),이지현(Ji-hyun Lee),김종철(Jong Cheol Kim) 한국차학회 2018 한국차학회지 Vol.24 No.2
Morphologic and physicochemical changes of shading cultivated tea (Camellia sinensis) tree leaves were investigated during 26 days with 95% shading treatment. Shading cultivation showed higher leaf area (10%) and moisture content (12%) than non-shading cultivation. The shading cultivation increased the total free amino acid (3.4-fold), theanine (3.7-fold), arginine (10.8-fold) and caffeine levels (2.0-fold) but decreased the total catechin contents, EGCG (epigallocatechin gallate) and EGC (epigallocatechin) levels of tea leaves. The SPAD value and total chlorophyll contents of the shading cultivation were increased by 1.1- and 2.1-fold, respectively. The results of a color analysis showed that lightness (L*) of non-shaded was higher than that of shading cultivated matcha. However, the greenness (a*) and yellowness (b*) of shading cultivated matcha were higher than those of non-shading cultivation. The surface color of shading cultivated matcha had higher chroma- and G-values than non-shading cultivated matcha, which represents real green color. Thus, the shading cultivation is suitable to prepare a high-quality matcha product.
주문맥침범과 임파절 전이를 동반한 Child 등급 B인 간세포암 환자에서 방사선치료와 sorafenib 병합으로 종양의 부분관해를 경험한
황상연 ( Sang Youn Hwang ),이선미 ( Seon Mi Lee ),임정우 ( Jung Woo Im ),김준석 ( Joon Suk Kim ),안상부 ( Sang Bu Ahn ),지은경 ( Eun Kyeong Ji ),강현철 ( Hyun Cheol Kang ),최철원 ( Cheol Won Choi ),양광모 ( Gwang Mo Yang ) 대한간암학회 2014 대한간암학회지 Vol.14 No.2
Reserved liver function is one of the most important determinants of survivial in advanced hepatocellular carcinoma (HCC). Especially in cirrhotic patient with decompensated liver function, sorafenib for HCC with main portal vein invasion have limited efficacy and survival benefit. Therefore many clinicians or centers still try locoregional therapy (LRT) such as transarterial chemoembolization (TACE), radiation therapy (RT), or combination with LRT and sorafenib in this situation. However this multidisciplinary approach may increase treatment related toxicity such as liver failure, etc. Recently, studies for combination of RT and sorafenib for HCC with portal vein invasion have been tried and reported not only bettertherapeutic efficacy, but also more hepatic toxicity.Based on above suggestions, we herein offer our experience of a patient that although achieved survival gain via partial remission of intrahepatic tumor and main portal vein thrombosis and metastatic lymph node by combination therapy of RT and sorafenib, finally expired due to hepatictoxicity. Further study, maybe regarding a combination of locoregional and systemic therapy, is necessary on how to manage decompenstated cirrhotic patients with HCC with main portal vein invasion. (J Liver Cancer 2014;14:120-126)
황정해(Jung Hae Hwang),백경임(Kyung Im Baik) 한국아동학회 2004 아동학회지 Vol.25 No.5
Based on ethnographic methods, the present research utilized individual interviews of 1 to 2 hours each with various probe questions to discover early stages of preparation for fatherhood. Interviews of the 12 male participants took place in naturalistic settings. Most were between 28 to 32 years of age and middle SES class. Results showed that during their wife`s pregnancy expectant fathers come to terms with becoming a father; they obtain a new understanding of life and make efforts to behave desirably in society; attitudes towards their own parents change; they have a different relationship with their wife; relations with close associates change, and occupational identity changes in that feelings of responsibility for a wife and child becomes more sincere.
부신, 폐전이를 동반한 거대 간세포암 환자에서 경동맥 화학색전술, 방사선 치료, sorafenib을 병합하여 간내암과 부신전이의 완전관해를 경험한 1예
황상연 ( Sang Youn Hwang ),이선미 ( Seon-mi Lee ),임정우 ( Jung Woo Im ),김준석 ( Joon Suk Kim ),안상부 ( Sang Bu Ahn,),지은경 ( Eun Kyeong Ji ),최철원 ( Chul Won Choi ),양광모 ( Gwang-mo Yang ) 대한간암학회 2013 대한간암학회지 Vol.13 No.1
Extrahepatic metastasis (EHM) associated with hepatocellular carcinoma (HCC) has been increasing due to prolonged survival with recent advances in therapeutic approaches including locoregional therapy such as transarterial chemoemoblization (TACE), radiofrequency ablation and radiation therapy (RT). Though many guidelines recommended systemic therapy such as sorafenib in this situation, some clinicians or centers still select locoregional therapy because the survival improvement of 2 or 3 months by sorafenib is far from optimal. Moreover, some studies showed that complete and partial response of intrahepatic tumors can result in significant improvement of patient survival even in situation of EHM. Based on above suggestions, we herein offer our experience of a patient with complete remission of intrahepatic tumor and adrenal gland metastasis treated with combination therapy of TACE and RT and sorafenib. Further study, maybe regarding a combination of locoregional and systemic therapy (so called multidisciplinary approach), is necessary on how to manage HCC patients with EHM.