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항 Signal Recognition Particle (신호인식입자) 항체와 연관된 근병증
홍현정,선우일남,신하영,김세훈,조정희,김승민 대한신경과학회 2011 대한신경과학회지 Vol.29 No.3
Myopathies associated with anti-signal-recognition particle (SRP) antibodies usually present with severe muscle weakness and exhibit necrotizing myopathy with little inflammation pathologically. Here we report a case of a 61-year-old man who presented with subacute progressive proximal muscle weakness, dysarthria, and dysphagia. Although polymyositis was expected clinically, muscle biopsy revealed myopathic changes with degenerating fibers without definite inflammation. Further laboratory study revealed that the patient was positive for anti-SRP antibodies.
보제소독음(普濟消毒飮)의 진통(鎭痛), 해열(解熱), 소염(消炎), 항균(抗菌) 및 항경련(抗痙攣)에 대한 실험적(實驗的) 연구(硏究)
홍현정,이한철,Hong Hyun-Jung,Lee Han-Cheul 대한한방소아과학회 1995 대한한방소아과학회지 Vol.9 No.1
Experimental studies were done to research the clinical effect of Bojeosodokeum on the Analgesic, Antipyretic, Anti-inflammatory, Antimicrobial and Anti-convulsive effects in mice and rats. The results obtained as follows : 1. The solid extract powders of Bojeosodokeum was revealed significant action on analgesic effect. 2. the solid extract powders of Bojeosodokeum was revealed significant action on Anti-inflammatory effect. 3. The solid extract powders of Bojeosodokeum was revealed significant action on antipyretic effect. 4. Antimicrobial effects of solid extract powders of Bojeosodokeum against Escherichia coli and staphylococcus aureus was observed. 5. The solid extract powders of Bojeosodokeum was revealed significant action on anticonvulsive effect. According to the above results, it is confirmed that analgestic, anti-inflammatory, antipyretic, antimicrobial and anticonvulsive effect were recognized in solid extract powders of Bojeosodokeum.
한국 노인의 일일 수분섭취 상태에 따른 주요 만성질환 유병률 및 탈수 예측 생리적 지표 탐색 연구: 2015년 국민건강영양조사 결과를 바탕으로
홍현정,김나현 기초간호학회 2018 Journal of korean biological nursing science Vol.20 No.2
Purpose: The aim of this study was to explore the prevalence of major chronic diseases related to daily oral water intake and to identify the physiological parameters related to dehydration in Korean elderly. Methods: The data were collected from the sixth Korea Health and Nutrition Examination Survey (KHANES), which was a nationwide and cross-sectional survey in 2015. We analyzed 1,392 participants using t-test and logistic regression. All participants were divided into the adequate water intake (AWI) group and the non-adequate water intake (NAWI) group based on the dietary reference intakes for Koreans. Results: There was a significant difference in the water intake between the AWI (6.8 cups in a day) and NAWI (2.8 cups) groups (p<.001). There was no statistically significant association between the level of water intake and any of the major chronic diseases. Blood urea nitrogen (BUN) and BUN/Creatinine (Cr) ratio were significantly higher in the NAWI group. Especially, BUN/Cr ratio shows that the NAWI group reached dehydration status. Older age (adjusted odd ratio, OR=1.07, 95% confidence interval, CI [1.04-1.10]), female gender (adjusted OR=1.56, 95% CI [1.05-2.33]), lower body mass index (BMI) (adjusted OR=1.00, 95% CI [0.92-1.00]), higher BUN (adjusted OR=1.04, 95% CI [1.01-1.08]), and higher urine specific gravity (USG) (adjusted OR=1.56, 95% CI [1.19-2.05]) were factors associated with the NAWI group. Conclusion: The findings suggest that the level of water intake needs to be considered in relation to age, gender, BMI, BUN, and USG. These are sensitive physiological parameters used for predicting dehydration of the elderly according to their daily oral water intake. It would be helpful to develop strategies to prevent dehydration in elderly individuals and enhance their water intake.
화학기상반응으로 흑연 위에 만든 SiC 반응층의 모양에 미치는 보론 카바이드의 영향
홍현정,류도형,조광연,공은배,신동근,신대규,이재성 한국세라믹학회 2007 한국세라믹학회지 Vol.44 No.8
A conversion layer of SiC was fabricated on the graphite substrate by a chemical vapor reaction method in order to enhance the oxidation resistance of graphite. The effect of boron carbide containing powder bed on the morphology of SiC conversion layer was investigated during the chemical vapor reaction of graphite with the reactive silicon-source at 1650oC and 1700oC for 1 h. The presence of boron species enhanced the conversion of graphite into SiC, and altered the morphology of the conversion layer significantly as well. A continuous and thick SiC conversion layer was formed only when the boron source was used with the other silicon compounds. The boron is deemed to increase the diffusion of SiOx in SiC/C system
양육태도가 청소년의 성의식 및 태도에 미치는 영향: 청소년 인권의식의 매개효과
홍현정 한국청소년복지학회 2018 청소년복지연구 Vol.20 No.4
The purpose of this study is to identify the effect of the main caregiver’s parenting attitude which adolescents perceived on adolescents’ sexual consciousness and sexual attitude, focusing on the mediating effects of the adolescent’s perception of the human right. Students from middle schools in Busan city responded to the questionnaire. 469 questionnaire were statistically analyzed. The results of this study are summarized as follows. First, adolescents’ perception of the human right had a partial mediating effect on the relationship between the main caregiver’s receptive parenting attitude and the adolesent’s sexual consciousness and sexual attitude. Second, the adolescent’s perception of the human right had a partial mediating effect the relationship between the main caregiver’s autonomous parenting attitude and the adolescent’s sexual consciousness and sexual attitude. Based on these findings, this study suggests methods to improve the main caregiver’s parenting attitude and the adolescent’s perception of the human right. 본 연구는 청소년이 지각한 주양육자의 양육태도가 청소년의 성의식 및 태도에 어떠한 영향을 미치는지를 청소년 인권의식의 매개효과를 중심으로 검증하고자 하였다. 이를 위해 부산시중학생을 대상으로 설문조사를 실시하고, 최종 469명의 자료를 통계 분석하였다. 주요 연구결과를 살펴보면 첫째, 청소년의 인권의식은 주양육자의 수용적 양육태도와 청소년의 성의식 및 태도 관계에서 부분매개효과가 있는 것으로 나타났다. 둘째, 청소년의 인권의식은 주양육자의 자율적 양육태도와 청소년의 성의식 및 성태도 관계에서 부분매개효과가 있는 것으로 나타났다. 이와 같은 결과를 바탕으로 주양육자의 양육태도 개선과 인권의식 함양 위한 방안을 제시해 보고자 한다.
특성화고등학생의 학교생활적응 예측요인 탐색: 성차를 중심으로
홍현정,안도희 인하대학교 교육연구소 2022 교육문화연구 Vol.28 No.5
본 연구에서는 부모자녀 관계, 회복탄력성 및 진로결정 자기효능감이 특성화고등학생의 학교생활적응을 예측해주는지에 대해 성별로 탐색하고, 성별에 따른 변인의 차이가 나타나는지에 대해 살펴보고자 하였다. 이를 위해 본 연구에서는서울시, 안양시 및 안산시에 소재한 특성화고등학교 재학생 총 362명을 최종 분석대상으로 하였다. 변인에 대한성별차이를 알아보기 위해 독립표본 t 검증을 수행하였으며, 학교생활적응 예측 요인 탐색을 위해 다중회귀분석을수행하였다. 본 연구결과, 여학생이 남학생보다 어머니의 ‘돌봄’ 요인, 회복탄력성의 ‘긍정성’ 및 ‘대인관계’ 요인, 진로결정 자기효능감의 ‘목표선택’, ‘직업정보’ 및 ‘문제해결’ 요인, 학교생활적응의 ‘사회적 적응’ 요인에서 높게나타났으며, 회복탄력성 전체, 진로결정 자기효능감 전체, 학교생활적응 전체에 있어서도 높게 나타났다. 특성화고등학생들의 학교생활적응에 있어 많은 영향을 미치는 요인을 탐색하기 위하여 단계적 다중회귀분석을 수행한 결과, 학교생활적응 전체에 있어 남녀 모두 회복탄력성의 ‘자기조절’, ‘긍정성’, ‘대인관계’ 요인, 진로결정 자기효능감의 ‘미래계획’. ‘직업정보’ 요인이 긍정적인 영향을 미치는 것으로 나타났다. 본 연구는 특성화고등학생들의 학교생활적응을 돕는요인을 밝혀냄으로써 학생들의 학업중단율을 감소시키는 데 도움을 줄 수 있을 것으로 기대된다.