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- 저자 : 홍숙희(Hong, Sook-Hee) (검색결과 103 건)
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한국인 일반 여성의 HPV 감염 유병율 -부산지역 일반 여성에서의 HPV DNA 및 항 VLPs 항체 양성 빈도 -
홍숙희,이덕희,신해림,Hong, Sook-Hee,Lee, Duk-Hee,Shin, Hai-Rim 대한세포병리학회 2004 대한세포병리학회지 Vol.15 No.1
To investigate a population-based survey of the prevalence of human papillomavirus (HPV) infection in South Korea, we performed Papanicolaou smears and tests for HPV DNA and anti-HPV antibody detection in 909 sexually active general women (age range; 20-74 years, median 44 years) who were randomly selected residents from S district of Busan City. The presence of DNA of 36 different HPV types was detected by means of a GP 5+/6+ primer-mediated PCR enzyme immunoassay in cervical exfoliated cells, and IgG antibodies against L1 virus-like particles (anti-VLPs) of 5 HPV types 16, 18, 31, 33, and 58 were tested by means of enzyme linked immunoassay. The incidence of cytologic abnormality was 5.2% in Pap smear. The positive rate of HPV DNA was 10.4%, high in young women younger than 35 years old and proportionally increased according to the cytologic grades. The most often found HPV type was HPV 70, followed by HPV 16 and 33, and high-risk HPV types were more frequent in women younger than 35 years old. The most common HPV type in abnormal cytologic smears was HPV 16, followed by HPV 58 and 66. Anti-VLPs was positive in 19.7% and the frequent anti-VLPs type was against HPV 18, followed by HPV 31 and 16. The concordance between the markers for each specific HPV type was noted in 10 women and HPV 16 was the most frequent one. The incidence of multiple HPV infection was 18.9% and that of multiple anti-VLPs antibodies was 31%. Among 103 self-reported virgins, 4.9% had anti-VLP antibodies.
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평생교육 기반으로서의 지역사회교육 논의의 역사적 변천 과정 탐색
홍숙희(Hong, Sook Hee) 한국평생교육학회 2010 평생교육학연구 Vol.16 No.1
본 연구는 지역 평생교육의 활성화가 강조되고 있는 우리사회에서 지역평생교육의 일환으로 이미 적용되어온 지역사회교육 논의를 중심으로 그 역사적 변천 과정을 고찰하고, 이를 기반으로 평생교육의 방향성을 모색해보고자 하였다. 이를 위해 본 연구는 지역사회교육의 전개과정을 검토하고, 지역사회교육 논의의 역사적 변천과정을 탐색하여 쟁점들을 검토함으로써 지역 평생교육으로서의 지역사회교육 논의의 방향을 분석하였다. 이를 바탕으로 한국 평생교육학의 발전을 위한 지역사회교육의 발전과제를 제시하였다. 첫째, 지역사회교육은 문제해결을 위한 프로그램뿐만 아니라 공동체 형성 지향의 과정으로서 초점이 맞추어져야할 것이며, 둘째, 특별한 정책이나 제도로서가 아니라 지역사회 구성원들과 교육서비스로서 관계를 맺는 전체를 대상으로 총체적이고, 체제적으로 접근되어야할 것이다. 셋째, 지역사회에서 진행되고 있는 교육․문화․복지․환경 등 전 방위적인 영역과의 관계성을 확립해 나가야할 것이며, 넷째, 지역사회교육의 특성을 반영한 연구방법론의 모색과 정립을 통해 지역사회교육학의 체계화를 모색해 나가야 할 것이다. This study attempted to explore the directivity of Lifelong Education based on examining the historical change process of Community Education discourses which had been applied as the part of Community Lifelong Education in our society. The goal of this paper is to examine the developmental process of Community Education and exploring the historical change process and issues of Community Education discourses, it analyzes the directivity of discourses of Community Education which are performed in our society. The research suggests the issues for improving Community Education to develop Life Education in Korea. First, Community Education will concentrate on the community-oriented process rather than the problem-solving programs. Second , Community Education should not be a specific policy or system, but should be arranged as a holistic and systematic approach on educational service which relates community members and the whole area. Third, it must try to establish the relationships among the omni-directional areas such as the education, culture, welfare, environment which are on the move in the community. Finally, Community Education needs to devise its systemization through constituting and seeking research methodology reflected in the characteristic of Community Education.
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위암의 (胃癌) 통계학적 관찰과 병리조직학적 (病理組織學的) 분류의 문제점에 대하여
홍숙희(Sook Hee Hong),석동수(Dong soo Suk),주종은(Jong Eun Joo),임인숙(In Sook Lim) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A Total 211 lesions of stomach cancer were collected from the pathology department of the Pusan Paik Hospital during 1979 and 1985. Statistical analysis was carried out showing the following findings; 1) Among the total 211 cancers, male 139 and female 72. The male-female ratio is 2:1. 2) Average age is 52 years, male 54.7 and female 47.5 years old. These figures are 7 years lower than Japanese, and 4 years lower than Americans, clearly suggesting higher carcinogenic agents present in the Korean environment (food). 3) The size of the gastric cancer is 2-5 cm in diameter in the majority of the cases. Those of female are 0.6 cm larger in the average diameter than those of male. 4) The site of the cancer is antrum in half of all cases, the next is body and pylorus. 5) Depth of cancer invasion into the gastric wall shows the serosa the most frequent, 37.4%, the next is subserosa, 28.4%. There was the Early Gastric Cancer in 11% among all cancers of the stomach. 6) Metastasis of the regional lymph nodes was found in 66.8%. The frequency of the metastasis is increasing proportionally with the size of the cancer and the depth of the cancer invasion in the gastric wall. 7) Histopathology of the stomach cancer shows in the following order; poorly differentiated(38.4 %), moderately differentiated(22.7%) and well differentiated(18.5%). Together of these three types consist of 80% of total lesions. There is a distinct difference between male and female on the histological types, for there are 52% in undifferentiated and 48% in differentiated types among male while 72% and 28% among female groups. In average, they are 60% and 40%, respectively. 8) Prominent infiltration of lymphocytes in the stroma is found 2-5% of the cancers. Promenent proliferation of fibrous connective tissue of the stroma is found in 3-9% of the cancers. 9) The distinct difference in female group such as lower age group and more frequent association with undifferentiated form, will be elucidated by genetic disposition, and should be tested by tissue typing. 10) The histopathological classification should be as those of the traditional detailed description of the histopathological types. It will be much benefitcial having a standard classicfication adopted by all institutes of Korea such as the currently adopted method of japanese institutes
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신부전을 동반한 신동맥 협착증 환자에서 Gadopentetate Dimeglumine 조영제를 이용한 성공적인 혈관 확장술
홍숙희 ( Hong Sug Hui ),송하헌 ( Song Ha Heon ),윤선애 ( Yun Seon Ae ),김영옥 ( Kim Yeong Og ),문성진 ( Mun Seong Jin ),김영수 ( Kim Yeong Su ),장기육 ( Jang Gi Yug ),장윤식 ( Jang Yun Sig ),방병기 ( Bang Byeong Gi ) 대한신장학회 2003 Kidney Research and Clinical Practice Vol.22 No.5
With the increasing number of interventional angiographic procedures, iodinated contrast induced nephropathy has become an important cause of iatrogenic acute renal failure. Gadopentetate dimeglumine, gadolinium chelated by DTPA, are widely used in magnetic resonance imaging without adverse effect on renal function in patioents with renal insufficiency. It also has sufficient radiographic density to allow visualization and has been described as an alternative contrast agent for angiography. Here we report a case of successful angioplasty using gadopentetate dimeglumine as a contrast agent in a patient with both renal artery stenosis and renal insufficiency. The patient had a history of iodinated contrast induced acute renal failure. Using this contrast agent, angioplasty was successfully performed and contrast induced acute renal failure did not occur after this procedure. (Korean J Nephrol 2003;22(5):602-607)
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홍숙희(Sook Hee Hong),최석렬(Seok Reyol Choi),김두형(Du Hyeong Kim),한상영(Sang Young Han),노명환(Myung Hwan Roh),허기영(Gi Yeong Huh),신우원(Woo Won Shin),김종성(Jong Seong Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5
N/A Background/Aims: This study is aimed to observe the expression of GST-z in colorectal adenomas and adenocarcinomas according to the risk and prognostic factors, and investigate the role during carcinogenesis and the possibility of clinical application as a tumor marker of colorectal neoplasm, in cornparision with the expression of p53 protein and CEA. Methods: Immuno- histochemical stain was performed in 15 cases of normal colon, 31 adenomas and 63 adenocarci- nomas. Results: The incidence of GST- expression was higher in adenocarcinoma (95.2%) than normal colon(40%), adenoma(87.1%) and adjacent norrnal mucosa to adenocarcinoma(63.5%) and the degree of the expression was also significantly different among them. In adenomas, the higher the degree of dysplasia, the higher the expression of GST-z. In adenocarcinomas, the expression was significantly decreased in relation with progression to lower histologic grade. The incidence of p53 expression was higher in adenocarcinomas(54.0%) than normal colon(0%), adenoma(25.8%) and adjacent normal mucosa to adenocarcinoma(0%) and the degree of the expression was also significantly different among them. In adenomas, the higher the degree of dysplasia, the higher the expression of p53. In adenocarcinoma, there was no sifnificant difference in relation with the histologic grade and stage. The incidence of CEA expression was higher in adenocarcinoma (96.8%) than normal colon(33.3%), adenoma(64.5%) and adjacent normal mucosa to adenocarci- norna(95.2%) and the degree of the expression was also significantly different among them. In adenomas, there was no significant difference in relation with size, amount of villous component and degree of dysplasia. In adenocarcinomas, the expression was increased in relation with progression to higher stage. The incidence of intense co-expression of GST-z and p53 in adenocarcinoma showed a tendency to be increasing in relation with progression to higher stage. But there was no statistically significant. Conclusions: It has been found from the above results that the expression of GST-z is progressively increased during colorectal carcinogenesiser. (Korean J Gastroenterol 1997;29:632-644)
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심병용,홍석인,박지찬,홍숙희,최강현,조홍주,김선영,한선애,이옥경,김훈교,Shim, Byoung-Yong,Hong, Seok-In,Park, Ji-Chan,Hong, Sug-Hui,Choi, Gang-Heun,Cho, Hong-Joo,Kim, Seon-Young,Han, Sun-Ae,Lee, Ok-Kyung,Kim, Hoon-Kyo 한국호스피스완화의료학회 2005 한국호스피스.완화의료학회지 Vol.8 No.2
Purpose: The lower extremity edema (LEE) is a common distressful symptom in advanced cancer patients and is hard to manage. We analyze the characteristics of LEE in patients with advanced cancer to provide the basic information of causes and adequate management. Methods: Physical examination, assessment of the location and severity of edema, blood chemistry (albumin, creatinine), Doppler Sono for patients with suspecting deep vein thrombosis (DVT), and abdomen CT scan for patient with suspecting lymph edema were performed. Severity of edema was classified according to NCI lymph edema scaling and improvement was defined as lowering at least 1 grade of edema after management. Results: Among 154 patient who had been admitted to Hospice Ward from Mar 2003 to Jan 2004, 33 had LEE, and 6 had both upper extremity edema and LEE except generalized edema. Their underlying cancers were stomach (7), lung (6), biliary tract (5), liver (5), colorectal (5), pancreas (2), and others (9). There were 12 patient with grade I, 20 patients with grade II, and 7 patients with grade III edema. The causes were hypoalbuminemia (11), lymph edema (10), DVT (7), obstruction of inferior vena cava (IVC) or portal vein (6), and dependent edema (5). The common managements were including leg elevation and diuretics. Elastic stocking was applied for patients with DVT and leg massage and pneumatic compression was used for lymph edema. The 2/3 patients were improved after management. Conclusion: The incidence of LEE in terminal cancer pts was high (25.3%) and their causes were variable including lymph edema, DVT, hypoalbuminemia and dependent edema. Active noninvasive management according to causes could result in good palliation. 목적: 하지 부종은 진행된 말기 암 환자에서 흔하게 발생하는 증상이며 치료하기 어렵다고 생각되고 있다. 우리는 말기 암 환자에서 하지 부종의 특성을 분석하고 원인과 치료에 관한 기본 정보를 얻기 위해 연구를 하였다. 방법: 하지 부종이 있는 환자에서 이학적 검사를 시행하고 부종의 범위, 정도, 혈액 검사(creatinine, albumin)을 시행하였다. 심부정맥 혈전증이 의심되는 환자는 Doppler 초음파를 시행하고 림프부종이 의심되는 환자는 복부 컴퓨터 단층 촬영을 시행하였다. 부종 정도는 NCI의 림프부종 평가를 이용하여 시행하였으며 증상의 호전은 부종의 정도가 1 이상 감소한 경우 호전이라 하였다. 결과: 2003년 3월부터 2004년 1월까지 총 154명의 호스피스 입원 환자 중 하지부종 환자는 39명이었으며 이 중 6명은 상지부종과 하지부종이 모두 있었다. 이 들의 원인 질환은 위암(7명), 폐암(6명), 간담도암(5명), 간암(5명), 대장암(5명), 췌장암(2명), 기타(9명)이었다. 원인으로써는 저알부민혈증(11명), 림프부종(10명), 심부정맥혈전증(7명), 하대정맥 또는 문정맥 폐쇄(6명), 의존성 부종(5명)이었다. 치료로는 하지 거상과 이뇨제를 사용하였으며 심부정맥 혈전증이 있는 경우는 탄력 스타킹을, 림프부종이 있는 경우에는 맛사지와 공기 압축을 이용한 재활 치료를 하였다. 전체 2/3환자에서 증상 호전이 관찰되었다. 결론: 말기 암 환자에서 하지 부종의 빈도는 25.3%로 높으며 원인 질환으로는 저알부민 혈증, 림프부종, 심부정맥혈전증, 의존성 부종 등 다양하다. 적극적인 비침습적 치료로 충분한 증상호전을 가져 올 수 있다.
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조광현,박동식,홍숙희,Cho, Kwang-Hyun,Park, Dong-Sick,Hong, Sook-Hee 대한흉부심장혈관외과학회 1982 Journal of Chest Surgery (J Chest Surg) Vol.15 No.2
The term hamartoma was first used by Albrecht to describe what he considered to be localized errors of development involving one or more tissue native to the organ of origin. The definition was meant to encompass not only abnormal local growth rate, but also the spatial arrangement, relative proportions and degree of the component tissue. But lately the major conclusions are that this group of lesion is neoplastic than developmental in origin. The Importance of pulmonary hamartoma is that they are relatively common among the benign tumor of the lung, but they usually present as asymptomatic coin lesion on chest x-ray film and were find out In routine check up and frequently mimic clinically the more common lung tumor such as cancer. Recently, we have experienced three cases of pulmonary hamartoma which were all discovered during routine chest film check up for certificate of health and evaluation of other disease. All of these were surgically resected with good result. Among the operations, one of these was mass enucleation and the others were lobectomy of lung involved by the mass.
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이상용,김대철,나서희,홍숙희,강태훈,이영호,남경진,정진숙,Lee, Sang-Yong,Kim, Dae-Cheol,Rha, Seo-Hee,Hong, Sook-Hee,Kang, Tae-Hun,Lee, Young-Ho,Nam, Kyoung-Jin,Jeong, Jin-Sook 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.1
Malignant rhabdold tumor is a distinct renal tumor in the pediatric age group. It was originally described as a rhabdomyosarcomatold variant of Wilms' tumor. However, subsequent studies fatted to confirm myogenous differentiation, so it is now considered to be a distinct and unique type of highly malignant tumor, histogenetically unrelated. Although extrarenal forms of this tumor are rare, several examples have been described in other sites, especially the liver, prostate, paravertebral area, urinary bladder and soft tissue. We experienced a case of malignant rhabdiod tumor located in the intraabdominal cavity in a 10 month-old boy. Smear of peritoneal fluid showed round, polygonal and irregular shaped cells with large nuclei, ample cytoplasm containing light pink to purple cytoplasmic inclusions, and one or a few prominent nucleoli. Immunocytochemistry revealed positivity to cytokeratin, epithelial membrane antigen and vimentin, and negativity to desmin and neuron-specific enolase. These distinct cytologic appearance and immunophenotypes were most consistent with a diagnosis of extrarenal malignant rhabdoid tumor. The cytoplasmic inclusions were correlated with eosinophilic inclusions seen in histologic section and electron microscopy confirmed this interpretation, showing filamentous aggregations in the cytoplasms of the tumor cells.
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