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홍경섭,남은우 中央醫學社 1994 中央醫學 Vol.59 No.3
The purpose of this study is to provide the data for the development of Oriental Medicine in Korea. This paper make a content analysis on the some research paper and government reports of the Japan. The results were as follows. First, according to major research fields are hospital related oriental medicine, herbal clinics, cognition to the Oriental Medicine, research staffs and budgets, utilization patterns of the medicine, and prospective of the Oriental Medicine by the professional groups in Japan. Second, the percentage of experiences to the Oriental Medicine is 49 %. Who use of acupuncture are 30 %. And they anticipate useful to the chronical diseases. Third, professional groups are having the opinion, the Oriental Medicine effects or takes effect a little or not, are 80 %, 20 %, respectively. As mentioned above, to understand the Japanese Oriental Medicine of the research fields, utilization pattern, and prospective to the Oriental Medicine will be references to develop Oriental Medicine policies in Korea.
평균유동이 있는 단순확장관의 기하학적 형상이 음향학적 특성에 미치는 영향 - 실험적 고찰
홍경섭,김양한,곽윤근,김광식 대한기계학회 1988 대한기계학회논문집 Vol.12 No.4
본 연구에서는 기존 자동차 소음기를 모델로하여 여러가지로 형상을 변화시켜 가면서 음향학적인 소음감소특성을 실험적으로 해석하였다. 또한 자동차에 부착되는 소음기는 배기가스의 유동이 있는 상태에서 음파의 대류현상이 존재하므로 이에 대한 모델로서, 공기 유동이 있는 경우에 대하여 각종 소음기 모델의 소음 감소 특성을 유 동속도별로 측정하여 해석하였다. The acoustical characteristics of silencer has been investigated by experimental methods. The relations between various geometrical parameters, i.e. length, diameter, offset and twisting angle of silencers and transmission loss have been studied. The effect of mean flow on the transmission loss was also investigated. Results show that experimental decomposition of flow and sound is possible. Experimental results which take into account for the effect of mean flows provide the accurated data which have not been found in the literature.
간이혈당측정기를 이용한 정맥 혈당 측정의 타당성 검증 -간이혈당측정기의 타당성 검증-
홍경섭 대한임상약리학회 2002 Translational and Clinical Pharmacology Vol.10 No.1
Background : Measurement of blood glucose is a basic part of patient care. Increasingly, blood glucose measurement has become a part of self-care. Devices featuring convenience and quickness are used to measure blood glucose and are used in settings often unsupervised by knowledgeable health care personnel. In this context, a validation test of a handy blood sugar measuring instrument(made by R. co. Ltd) will provide health care professionals and consumers with some assurances that the devices that they are using or purchasing are capable of producing valid results. Method : In this study, we fulfilled requirements from the ICH Q2 guidelines for assurance of accuracy, precision, linearity and range. From the two subjects, blood glucose was measured repeatedly at post-prandial 1h/2h/3h/4h, 12 times each , by two investigators and with two instruments. Then, we compared the results of a handy blood sugar measuring instrument with those of a chemistry analyzer, Hitachi 7070 auto-analyzer, in a core laboratory in Clinical Trial Center, Seoul National University Hospital. Results : Mean accuracy, intra-assay precision and intermediate precision were 92.6%, 2.3%(min. 1.07%, max. 4.51%), 1.73%(min. 0%, max. 5.65%) each. In scatter plot of the results of a handy blood sugar measuring instrument and Hitachi 7070 auto-analyzer, linearity was apparent and the correlation coefficient(r), r2 was 0.986 and 0.972 each. Conclusions : Mean accuracy was not satisfactory regarding the criteria for quality control of blood glucose measurement(within ±5%) in SNUH. The intermediate precision was also not satisfactory regarding the criteria for Quality Control (less than 5%).
간이혈당측정기를 이용한 정맥 혈당 측정의 타당성 검증 - 간이혈당측정기의 타당성 검증 -
홍경섭,배균섭,임형석,정재용,김묘경,백정미,강경자,박귀주,신상구,장인진,Hong, Kyoung-Sup,Bae, Kyun-Seop,Lim, Hyeong-Seok,Chung, Jae-Yong,Kim, Myo-Kyoung,Baik, Jung-Mi,Kang, Kyoung-Ja,Park, Gui-Ju,Shin, Sang-Goo,Jang, In-Jin 대한임상약리학회 2002 臨床藥理學會誌 Vol.10 No.1
Background : Measurement of blood glucose is a basic part of patient care. Increasingly, blood glucose measurement has become a part of self-care. Devices featuring convenience and quickness are used to measure blood glucose and are used in settings often unsupervised by knowledgeable health care personnel. In this context, a validation test of a handy assurances that the devices that they are using or purchasing are capable of producing valid results. Method : In this study, we fulfilled requirements from the ICH Q2 guidelines for assurance of accuracy, precision, linearity and range. From the two subjects, blood glucose was measured repeatedly at post-prandial 1h/2h/3h/4h, 12 times each, by two investigators and with two instruments. Then, we compared the results of a handy blood sugar measuring instrument with those of a chemistry analyzer, Hitachi 7070 auto-analyzer, in a core laboratory in Clinical Trial Center, Seoul National University Hospital. Results : Mean accuracy, intra-assay precision and intermediate precision were 92.6%, 2.3%(min. 1.07%, max. 4.51%), 1.73%(min. 0%, max. 5.65%) each. In scatter plot of the results of a handy blood sugar measuring instrument and Hitachi 7070 auto-analyzer, linearity was apparent and the correlation coefficient(r), $r^2$ was 0.986 and 0.972 each. Conclusions : Mean accuracy was not satisfactory regarding the criteria for quality control of blood glucose $measurement(within {\pm}5%)$ in SNUH. The intermediate precision was also not satisfactory regarding the criteria for Quality Control (less than 5%).
홍경섭,김유선,한동수,최창환,장병익,박영숙,이수택,이강문,김현수,김주성 거트앤리버 소화기연관학회협의회 2010 Gut and Liver Vol.4 No.3
Background/Aims: Ciprofloxacin has been widely prescribed for acute infectious diarrhea. However, the resistance to this drug is increasing. Rifaximin is a novel but poorly absorbed rifamycin derivative. This study evaluated and compared the efficacies of rifaximin and ciprofloxacin for the treatment of acute infectious diarrhea. Methods: We performed a randomized controlled multicenter study in Korea. Patients with acute diarrhea were enrolled and randomized to receive rifaximin or ciprofloxacin for 3 days. The primary efficacy endpoint was the time to last unformed stool (TLUS). Secondary endpoints were enteric wellness (reduction of at least 50% in the number of unformed stools during 24-hour postenrollment intervals), general wellness (subjective feeling of improvement), and proportion of patients with treatment failure. Results: Intent-to-treat analysis (n=143) showed no significant difference between the rifaximin and ciprofloxacin groups in the mean TLUS (36.1 hours vs 43.6 hours, p=0.163), enteric wellness (49% vs 57%, p=0.428), general wellness (67%vs 78%, p=0.189), or treatment failure rate (9% vs 12%, p=0.841). The adverse events did not differ significantly between the two groups. Conclusions: These results suggest that rifaximin is as safe and effective as ciprofloxacin in the treatment of acute infectious diarrhea.