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      • KCI등재

        Meridian-Test를 이용한 어깨질환의 임상증례 보고

        형균,원제훈,우창훈 한방재활의학과학회 2019 한방재활의학과학회지 Vol.29 No.3

        This study is to report the effectivenes of Meridian-Test (M-test) in 2 cases on shoulder diseases. The M-test was applied to one patient diagnosed with as impingement syndrome and one patient diagnosed with tear of supraspinatus tendon. The changes in numeral rating scale and range of motion were identified to assess the progress of the treatment. After three times treatments, In example 1, the pain decreased from 6 to 0.5 and the range of flexion and abduction increased from 150° to 180°. In example 2, the pain decreased from 6.5 to 1, and the range of shoulder flexion increased from 120° to 170°, while the range of abduction increased from 90° to 170°. Based on the above results, it would be effective to apply M-test to treat shoulder diseases in these two cases. (J Korean Med Rehabil 2019;29(3):173-182)

      • KCI등재

        출부탕(朮附湯) 추출물의 항산화 및 항염증에 대한 효과

        형균 ( Kyun Hyeong ),원제훈 ( Je-hoon Won ),우창훈 ( Chang-hoon Woo ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.3

        Objectives Even though the various alternative herbal medicine has applied for osteoarthritis (OA) treatment, its scientific proof remains uncertain. The aim of the present study evaluates the effects of Chulbu-tang on inflammatory responses in a monosodium iodoacetate (MIA)-induced osteoarthritis rat model. Methods OA rat model was established by MIA injection in intra-joint of rats. 7 days after, OA rats except OA control rats were administrated Chulbu-tang (100 or 200 mg/kg) or Indomathacin (5 mg/kg) once a day for 14 days. The weight-bearing ability of hind paws were measured when group isolation 0, 7, and 14 days. Western blotting was performed to examine the knockdown/overexpressing efficiency of Chulbu-tang. In addition, cartilage destruction was measured histologically. Results Chulbu-tang treatment significantly reduced the protein expressions of inflammatory mediators such as inducible nitric oxide synthase and cyclooxygenase 2, and inhibited inflammatory cytokines including tumor necrosis factor alpha, interleukin (IL)-1β, and IL-6 through nuclear factor-kappa B (NF-κB) inactivation. Moreover, anti- oxidant enzymes such as superoxide dismutase and glutathione peroxidase-1/2 through nuclear factor-erythroid 2-related factor 2 (Nrf2) pathway significantly increased. Our findings indicate that Chulbu-tang has the potential therapeutic effect on OA through inhibiting the inflammatory responses via inactivating NF-κB signaling pathway. In addition, upregulation of Nrf2 led to anti-oxidant effects. Conclusions Taken together, Chulbu-tang is believed to have antioxidant, anti-inflammatory effects, and cartilage protection for arthritis-causing rats. (J Korean Med Rehabil 2020;30(3):71-87)

      • KCI등재

        Formation of V-Shaped Pits in Nitride Films Grown by Metalorganic Chemical Vapor Deposition

        형균,Jeong Yong Lee 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.III

        We have investigated the formation of V-shaped pits in nitride films such as InGaN/GaN and AlGaN/GaN grown on sapphire substrate using transmission electron microscopy. The mechanism of pit formation strongly depends on the indium (In) and aluminum (Al) compositions in In$_x$Ga$_{1-x}$N and Al$_x$Ga$_{1-x}$N layers, respectively. With increasing the indium composition, V-shaped pits originated from the vertex of threading dislocations to the stacking mismatch boundaries induced by stacking faults and the three-dimensional island growth at the initial stage due to the large lattice mismatch. With increasing the aluminum composition, the origin of the pits also varied from the surface undulation due to the elastic misfit strain to the vertex of threading dislocations.

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