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현진해(J H Hyun),황일순(I S Whang),박민희(M H Park),전훈재(H J Chon),이상우(S W Lee),유호상(H S Ryu) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A From January 1980 to January 1987, a clinical study of 192 cases with colorectal cancer was made in Korea University Haehwa Hospital. The following results were obtained; 1) The peak age incidence was in sixth decade with 68 (35.4%) patients. 2) The male to female ratio was 1.13:l. 3) The location of tumor was in the rectum (36.1%), sigmoid colon (23.7%), ascending colon, descending colon and transverse colon in that order of frequency. 4) Bowel habit changes were the most common complaints. Abdominal pain and bloody stool were next common in rectosigmoid colon cancer cases. 5) Stool occult blood was positive in 63% of the cases. 6) Titer of carcinoembryonic antigen was over 10 ng/ml in 52.6% of the cases. 7) On gross pathologic finding, the exophytic type was the most common and according to Dukes classification, the stage C, was the most common regardless of tumor location.
홍진숙 ( J. S. Hong ),김춘원 ( C. W. Kim ),김유선 ( Y. S. Kim ),현진해 ( J. H. Hyun ) 대한내과학회 1973 대한내과학회지 Vol.16 No.2
A case of acute yellow atrophy of the liver due to Amanita genus is presented. Amanita genus, especially A. phalloides and A. verna, are cytotoxious and induce clinical manifestations of tissue damage of the liver, kidney and central nervous system etc. A
식도운동질환에 있어서 동위원소 식도통과검사와 식도내압검사의 비교연구
오정진(J . J . Oh),송치욱(C . W . Song),현진해(J . H . Hyun) 대한내과학회 1994 대한내과학회지 Vol.47 No.5
N/A Objectives : Esophageal manometry and radionuclide esophageal transit study (RETS) are important tests for the esophageal motor function. So far, there are little available report concerning the correlation between two methods. In the present study, we have compared the results of esophageal manometry and RETS. Methods : Total 66 human subjects were employed in this study including 20 normals, 24 nonspecific esophageal motility disorders, 9 achalasia, 6 diffuse esophageal spasm, 3 hypertensive LES, 2 nutcracker and 2 scleroderma. In each subject, esophageal manomertic study was performed with low compliance pneumohydraulic capillary infusion system. Within 2 days of manometric study, each subject was studied for radionuclide esophageal transit using liquid containine 0.5 μci of Tc-99m tin colloid in supine position. Manometric parameters includes amplitude (A), duration (D) of the distal esophageal contraction, velocity (V) and prevalence of peristalsis (P), The number of abnormal contractions (ACT) and lower esophageal sphincter pressure (LESP) were also included in the parameters. Esophageal pressure (LESP) were also included in the parameters. Esophageal transit time (ETT) was defined as the time taken to reach 10% of the peak activity from the entry of the radionuclide. Results : In normal subjects, the mean ETT was 8.5±6.5 seconds (M±SD) and the mean manometry parameters including A, D, P, V, ACT and LESP were 86.3±37.2 mmHg, 98.2%, 3.4±0.9 cm/sec, 0.1±0.2 and 29.5±4.5 mmHg, respectively. In patients with various esophageal motility disorders ETT was delayed in variable degree from less than 15 seconds to more than 300 seconds. In order to find possible correlation between the ETT delay and manometry parameters, each parameter was compared in relation to ETT by regression analysis. We found an intimate relationship between ETT versus amplitude (r=-0.56, p<0.001), prevalence of perisalsis (r = -0.63, p<0.0001), velocity (r =-0.46, p<0.0015), and number of abnormal contractions (r=0.47, p<0.0011). However, neither duration of esophageal contraction nor LESP related to the ETT delay. Conclusions : Among the esophageal manometry parameters, A, V, P, ACT are related with esophageal transit. However, changes in LESP and duration of contraction are less important to estimate the esophageal transit.
현진해,조원용 대한소화기내시경학회 1988 Clinical Endoscopy Vol.8 No.1
Endoscapic polypectomy or incisional enucleation was performed to 10 cases of esophageal submucosal tumor, from March, 1984 to January, 1988, using biopsy forcep, loop snare with high frequency electric current. The results were as follows. 1) In 10 cases 3 were male and 7 were female, with mean age 49. 2) Tumors were located lower esophagus in 5 cases and middle esophagus in 5 cases. 3) The presenting symptoms were mainly nonspecific, not related to underlying submucosal tomor. 4) In 8 of 10 cases, the procedure was performed completely, and so tumors were removed successfully. And in 2 cases, only biopsy for pathologic diagnosis was performed. 5) Results of histologic examination of these tumors were leiomyoma in all cases, In conclusion, we recommand endoscopic polypectomy or incisional enucleation as safe and effective method for esophageal submucosal tumor to make correct pathologic diagnosis and to treat the tumor.
신복합제산제(新複合制酸濟)에 의한 위염(胃炎)및 소화성궤양치료(消化性潰瘍治療)에 관한 임상적(臨床的) 연구
김정묵,황규찬,유선목,현진해,고광도 대한소화기학회 1976 대한소화기학회지 Vol.8 No.2
In this paper the clinical trial with a new antacid-compound was performed on 5 cases of acute gastritis, 11 of chronic gastritis, 12 of gastric ulcer and 20 of duodenal ulcer. The results were as follows. The complaints of patients were subsided well or excellently in 89. 7 per cent of the cases within 3 weeks after oral administration. The results obtained from X-ray findings and endoscopic findings as a clinical examination confirmed 6S, S per cent of the cases were good. Severe side effect by drugs were not observed in all cases.