중증근무력증환자의 혈장교환요법

현정애,전종찬,하경임,전동석,김재룡 대한임상병리학회 1988 대한임상병리학회지 Vol.8 No.2

Acquired B antigen에 의한 ABO불일치 2례

현정애,하경임,전동척,김재룡 大韓血液學會 1987 大韓血液學會誌 Vol.22 No.2

모세관 중합효소연쇄반응에 의한 결핵균검출

현정애,전효진,김재룡,전동석,이원길,은상진,최성만 대한임상병리학회 1995 대한임상병리학회지 Vol.15 No.2

도립(-6。)에 의한 심장혈관계 및 혈중 Catecholamine농도의 조기 변화

채의업,배재훈,현정애 啓明大學校 醫科大學 1991 계명의대학술지 Vol.10 No.1

Head-down tilt at -6℃ has been used as an experimuntal model to evaluate the effect on hemodynamics by movemunt of blood toward the central portion of the body under the conditions of weightlessness. So far there are a few disagreements between the findings reported by the different authors about early hemodynamic effects of heas-down tilt. Therefore, this study was done for the purpose to determine the early changes of hemodynamics and plasma catecholamine levels at head-down tilt from the prone position, which is more familiar than the supine position in the dog. Ten mongrel dogs weighing 8-12kg were anesthetized with the intravenous infusion of nembutal(30mg/kg), and the electromagnetic flow transducers were set up on the left common carotid and the right femoral artery to measure blood flow. Arterial pressure was measured directly by the strain gauge pressure transducer. Heart rate and respiratory rate, and pH, Po2, Pco2 and hematocrit of arterial and venous blood were also measured. The concentration of plasma epinephrine and norepinephrine was determined by Peuler and Johnson's radioenzymatic method. The postural changes were performe from the supine to the prone position, from the prone to the head-down position, and then to the prone position after head-down tilt and each posture was maintained for 30 minutes. The results are summarized as follows: When the posture was changed from the supine to the prone position, mean arterical pressure, heart rate, respiratory rate, blood flow of common carotid artery and plasma epinephrine level were increased, and blood, flow of femoral artery was decreased. Tilting to the head-down position from the prone position, arterial pressure was increased initially and maintained thereafter, and heart rate was slightly decreased and then gradually increased. Blood flow of common carotid artery was revealed a persistent increase, but that of femoral artery was not significantly changed. The change of carotid peripheral artery resistance was not significant, and femoral peripheral artery resistance was slightly increased, and respiratory rate was increased. At 30 minitues of head-down tilt, plasma norepinephrine level was slightly decreased and epinephrine level was increased. In the early phase of the recovery prone position after head-down tilt, arterial pressure and heart rate were significantly(p<0.01) increased comparing to the values at the end of the head-down tilt, and the higher arterial pressure was shown persistently during the recovery prone position. The changes of blood flow of common carotid artery and carotid peripheral artery resistance were not significant, but in the femoral artery, blood flow was decreased and femoral peripheral artery resistance was increased. Respiratory rate was not significantly changed. At 30 minutes of the recovery prone position after head-down tilt, plasma norepinephrine level was increased and plasma epinphrine level was significantly(p<0.05) increased comparing to the values at the end of head-down tilt. Through the periods of the serial postural changes, the changes of pH of arterial and venous blood were not significant, and gradual increase of Po2 and on the contrary gradual decrease of Pco2 wer revealed, their hematocrit were increased since 30 minutes of head-down tilt. In conclusion, when the posture is changed from the supine to the position, the heart rate is significantly increase and the other changes of cardiovascular systems are not significant. At the early stage of head-down tilt, the heart rate is transiently decreased and it is suggestive that cardiopulmonary baroreceptor is adequately operated according th the increased venous return from the lower body, however the arterial pressure and the blood flow of common carotid artery are increased thereafter. The significant rise of arterial perssure and heart rate in the recovery prone position after head-down tilt may be a result of the pressor reflex by the cardiopulmonary baroreceptor according to the diminution of a hydrostatic pressure produced by the head-down tilt, which is evidenced by an elevation of the plasma catecholamine levels.

이식폐장의 핵의학검사

전석길,현정애 啓明大學校 醫科大學 1995 계명의대학술지 Vol.14 No.4

폐질환환자의 동맥혈가스분석

현정애,김재룡,전동석 啓明大學校 醫科大學 1986 계명의대학술지 Vol.5 No.2

Arterial blood gas anlysis has been established as an important aid to diagnosis, therapy, and prognosis in pulmonary diseases. Authors analyzed the results of arterial blood gas analysis of 136 pulmonary disease patients requiring oxygen therapy at the emergency room. In patients with chronic obstructive pulmonary disease, the findings are consistent with respiratory acidosis, PCO₂being abnormally high in 53.3% of the cases and PO₂below 80mmHg in 88.9%. In patients with bronchial asthma, the PO₂levels were higher than ones with chronic obstructive pulmonary disease but the results of remaining parameters were essentially similar. The patients of lung cancer were significantly iincreased in pH, comparing with ones of other pulmonary diseases (p<0.005), and significantly fell in PCO₂comparing with ones of bronchial asthma (p<0.01).

최근 5년간 성분수혈의 변화

전동석,현정애,김재룡,하경임,전종찬 啓明大學校 醫科大學 1998 계명의대학술지 Vol.7 No.1

The immediate objective of most blood transfusion is to increase the oxygen -carrying capacity of the patient's circulation. Since this can be accomplished with the use of packed red cells alone, the common practice of transfusion of hole blood has been criticized as wasteful. The use of packed red cells allows the preparation of whole blood components, primarily platelets and fresh-frozen plasma, for those patients with specialized bleeding disorders and who do not necessarily need an increase in oxygen-carrying capacity. We observed the changes in component transfusion from 1983 through 1987. Total units of blood transfuse for 5 years were 83,213 units and the use of blood components increased from 17.8% to 51.1% from 1983 to 1987. Large annual increases in the use of packed red cells, fresh-frozen plasma and platelet concentrates occured during 5 years. The apheresis use for transfusion increase from 59 units to 3.8 units from 1985 to 1987.

Myelodysplastic syndrome을 동반한 유전성 타원형 적혈구증 1예

전동석,하경임,현정애,송홍석,김재룡 大韓血液學會 1987 大韓血液學會誌 Vol.22 No.2

Early Allograft Lung Perfusion Scan in Canine Single Lung Transplant

박창권,전석길,현정애 대한핵의학회 1995 핵의학 분자영상 Vol.29 No.2

Extra LD6 Isoenzyme Band 1례

하경임,전동석,김재룡,현정애,전종찬 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.1

Normal human serum and tissue, except testis, show five lactate dehydrogenase isoenzymes on electrophoresis. An unusual band on the cathodic side of LD?? isoezyme has been found on lcatate dehydrogenase eletrophoresis of serum, called LD??, and the presence of which signifies a poor prognosis for the patients. The autors experience one case of LD?? Extraband in 61-year-old female patient suffered from rheumatic heart disease combined with aortic stenosis and regurgitation, congestive heart failure and pulmonary edema. Cardiac arrest was noted within several hours after exhibition of LD?? Extraband and she did not recover from her illness, so we report with brief review of literatures.