만성 B형 간염 바이러스 감염자에서 혈청 HBV DNA 양과 간조직 소견의 관련성

허정호 ( Heo Jeong Ho ),허정 ( Heo Jeong ),권대식 ( Kwon Dae Sig ),문재현 ( Mun Jae Hyeon ),김광하 ( Kim Gwang Ha ),강대환 ( Kang Dae Hwan ),송근암 ( Song Geun Am ),조몽 ( Jo Mong ),양웅석 ( Yang Ung Seog ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.3

Background/Aims: Serum HBV DNA levels are correlated with hepatic histologic activity in chronic HBV infection based on HBeAg. Liver injury may persist, even though HBV DNA are not detected by hybridization assay. This study was to investigate whether serum HBV DNA levels determined by more sensitive quantitative method are correlated with histologic activities in chronic HBV infections. Methods: This study included 66 chronic HBV infected patients. HBV DNA level was quantified by Cobas Amplicor HBV MonitorTM. Results: Serum HBV DNA levels in HBeAg-positive patients were significantly higher than HBeAg-negative patients. In HBeAg-positive patients, serum HBV DNA levels showed a significant negative correlation with portal-periportal activity and fibrosis (r=-0.451, -0.446 respectively). AST levels were correlated with lobular, portal-periportal activity and fibrosis (r=0.432, 0.365, 0.301 respectively), whereas ALT levels were related to lobular activity (r=0.294). Elevated AST levels predicted lobular activity, portal-periportal activity, and fibrosis with moderate to severe degree (OR 1.733, 95% CI 1.083-2.775; OR 1.518, 95% 1.028-2.243, p=0.336; OR 17.897, 95% CI 1.517- 211.208, p=0.022, respectively). Conclusions: In HBeAg-positive patients, serum HBV DNA level correlates inversely with histologic activity. On the other hands AST level correlates with histologic activity and the stage of moderate or severe degree. (Korean J Gastroenterol 2003;42:220-225)

도축처리 단계별 도체 및 환경재료에 대한 미생물학적 분석

허정호 ( Jeong Ho Heo ),박영호 ( Yeong Ho Park ),구정현 ( Jeong Hyen Koo ),조명희 ( Myung Hee Cho ),이주홍 ( Joo Hong Lee ),임삼규 ( Sam Kyu Rim ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.21 No.2

To get the information of sanitary develoment of beef and pork, we get the result of environmental specimens(slaughter house floors, sewage, etc) in laboratory. 1. After examination of bacterial infection on after-bleeding, after-dismemberment and final products at each stage of cattle slaughter process, we got log 3.80~7.48cfu/cm2 of aerobic plate counts and log 2.60~5.23cfu/cm2 of coliform counts or so from the carcasses after bleeding, but these count levels went down little bit after dismemberment but as we continued study to the final products, the count levels kept sililar in mumbers. 2. At the slaughter process of pigs, the aerobic plate counts and the coliform counts reached such high levels of log 5.59~8.80cfu/cm2 and log 3.31~5.67cfu/cm2, respectively, after bleeding, in general, these count diminished in a big way after scalding, but they increased just little bit from dismemberment to final products. And there were few differences in the contamination levels on the final products no matter what seasonal contaminations after bleeding. 3. Test revealed very low levels of cell counts both on the aerobic plate counts of washing water and in the coliform counts, the former was log 1.00~2.69cfu/cm2 and the later was log 3.30~5.67cfu/cm2, but the contamination levels on the beds of transfering vehicles for carcasses were very high as followes: the aerobic counts was log 4.23~7.20cfu/cm2 and coliform counts was log 2.86~5.20cfu/cm2 4. Study showed the aeroboc plate counts and the coliform counts get to the highest levels in summer, the second highest one is in fall, the third in spring, lowest in winter. Resulting from the test results proven above we reached this kind of conclusion the bacterial contaminations on eatable carcasses were upto hygienic treatment of carcasses and cleaniness of transferring vehicles at the final stop of slaughter processes rather than upto at any stage of slaughter processes. Therefore we have got to establish alternatives immediately to develo sanitary quality of meat and Pork.

경남 남부지방의 흑염소 사양관리 및 내부기생충 감염실태 조사

허정호 ( Jeong Ho Heo ),정명호 ( Myung Ho Jung ),조명희 ( Myung Heui Cho ),안동원 ( Dong Won Ahn ),이순선 ( Sun Seon Lee ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.22 No.1

Research results on actual management situation of 16 goat farms and internal parasite infection of 155 goats from January to November in 1997 in southern Kyoungnam area were as follows; 1. An average number of goats was 93. Among them, 81 % were farming the goat as avocation with the income rate less then 50%. Eight-four percent of farms terminated the parasites more than twice a year, and the survey showed the black goats had a high digestive and respiratory disease infection rate. 2. The internal parasite infection rate of the black goat was 96.8%, the goats were infected with 13 types of parasites. Of them, Emeria sp was 87.1%, Ostertagia sp 55.5%, Paraphista-num sp 45.8%, and Moniezia expansa 20%, respectively. 3. On the survey of multiple infection rate, both double and triple infection were 19.4%, more than septuple-infection 15,5%, single infection 13.4%, quintuple infection 12.3%, sextuple infection 9.0% and quadruple infection 7.7%, respectively. 4. Look over on seasonal infection rate, higher in fall and lower in winter. Especially, Paramishi-tom sp was higher in summer and winter, both Moniezia expansan and Bonaostom sp were higher in summer. 5. Research on the infection rate of parasites termination period revealed less-than-l-month period had 10-30 infection rate, the infection rate has increased sharply since 3 months passed after the goats were treated with parasite-cid.

도축처리 단계별 도체 및 환경재료에서 Listeria monocytogenes의 분리

허정호 ( Jeong Ho Heo ),손성기 ( Seong Ki Son ),이주홍 ( Ju Hong Lee ),임삼규 ( Sam Kyu Rim ),구정헌 ( Jeong Heon Ku ),박영호 ( Yeong Ho Park ),조명희 ( Myung Hi Cho ),손원근 ( Won Geun Son ),강호조 ( Ho Jo Kang ) 한국가축위생학회 1997 韓國家畜衛生學會誌 Vol.20 No.1

To invastigate the epidemiological trait of listeriosis, Listeria monocytogenes were isolated from the carcasses of pigs and cattle, and environmental specimens in slaughter house. Also serotype of isolates were classified by rapid slide agglutination test. In the carcasses of pigs, Listeria sp were isolated from the carcasses after bleeding(62%), after dismemberment(60.0%) and before shipping(76.0%), and L monocytogenes were present in 8% of the carcasses after dismemberment and in 14% of the carcasses before shipping. However, few Listeria sp were isolated from the living body skin and the carcasses after scalding. In the carcasses of cattle, Listeria sp were isolated from the carcasses after bleeding(10%), after dismemberment(36.7%) and before shipping(63.3%), L monocytogenes were present in 3.3% of the carcasses after dismemberment and in 10% of the carcasses before shipping. Overall, L monocytogenes, L innocua, L welshimeri, L grayi, and L murrayi were present in 4.8, 40, 2.3, 2.6 and 0.3% of all the carcasses, respectively. Prevalence of Listeria sp in environmental specimens were found to be 80% in slaughter house floors and 100% in sewage, and L monocytogenes were present in 15% of sewage. However, few Listeria sp were isolated from chilled water and from scalding water. Overall, L monocytoge-nes, L innocua, and L welshimeri were present in 3.8, 45 and 6.3% of all the environmental speci-mens, respectively. A total 27 strains of L monocytogenes were isolated from samples tested and all of the strains were classified into serotype 1.

젖소 유방염 관리에 따른 세균 및 체세포수 등급 실태 조사 분속

허정호 ( Jeong Ho Heo ),정명호 ( Myung Ho Jung ),박영호 ( Yeong Ho Park ),조명희 ( Myung Heui Cho ),이주홍 ( Ju Hong Lee ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.21 No.3

1. The number of average milking cows, clinical forms of mastitis, mastitis-developing cows, and cows killed by mastitis a year were 25.7, 1.8(7%), 6.3(26%), and 2.7(10.1%)heads, respectively. The annual grade changes of standard plate counts(SPC) and somatic cell counts(SCC) showed the grade 1A of SPC diminished sharply from April to August, we think it was due to the lack of proper management in farming season and the grade 3 of SCC indirectly influenced increased in huge during August. 2. The average number of parturitions of farms was 2.3, but 50% of below 1 parturition were 22 farms(31%), 50% of above 3 parturitions were 16(23%) out of 71 farms. According to grades of the number of parturitions of milking cows per each farm, the farms` grades recording 3 parturitions and 50% were little bit excellent. 3. The actual situation research of foremilking CMT revealed 35 out of 74 farmers didn`t do CMT. Among them(35 out of 74 farmers), 80% did not test thanks to the troublesome process of the CMT. SCC grade 3, among farms who did foremilking CMT once or twice a month and who did not were 29% and 40% respectively and SPC grade 1A were 55% and 9%, respectively. 4. The research of actual situation on milking management let us know 29 farm s(39%) did not do lastmilking, 37 farms(49%) usually did overmilking, and 34 farms(46%) did milking for 4 or 5 minutes. Grades according to average requiring times of milking showed SCC grade 1 of farms milking within 7 minutes was 11% and SPC grade 1A was 34%, on the other side, farms milking more than 7 minutes were 0% in SCC grade 1 and 13% in SPC grade 1A. Grades according to the starting time of milking after rubbing teats showed SPC grade 1A of farms starting milking at about 1 minute and over 2 minutes were 50% and 20%, respectively. 5. The research of actual situation on hygienic milking management uncovered 65 farms(88%) were using one towel which was used in washing teats and udders to wash more than 3 to 4 cows, and 53 farms(72 %) were using one dried towel to dry udders not for each cow but for more than 3 to 4 cows after washing. Also, on milking turns disclosed 30 farms(40%) were milking cows in the order of incoming without isolation of a dominant group. According to grades of towels used in washing teats and udders, farms using a towel for each cow were 56% and a towel for over 3 cows were 31% in SPC grade 1A. According to using-or-not grades of dried towels after washing udders, farms using a towel for each cow were 79% and a towel for over 3 cows were 21% in SPC grade 1A. 6. Farms doing teat-dipping before milking were 7(10%), not doing teat-dipping after milking, or doing sometimes were 9(12%), and doing right after milking were 57(77%). And farms doing teat-dipping after dry cows and before delivery were 21(28%). Farms using bethadine as an antiseptic solution were 70(95%), 40 farms(59%) diluted it with water as weak as 5 to 10 times, and on drying cows 64 farms(87%) slowly did it more than 2 days. Grade 1A of SPC of farms doing teat-dipping at every milking was 38%, farms doing occasionally or not was 33%, and farms doing it right after milking was 37% and doing after milking more than 5 cows was 20%. Grade 1A of SPC among farms diluting bethadine 5 times and diluting 5 to 10 times with water were 36% and 33%, respectively, and Grade 3 of SCC were 35% and 32%, respectively. 7. Studies on nonlactating period medical treatment, as the cows were on dry, 54 farms treated with their own hands. 73 farms(98%) had bovine mastitis treated for themselves. And on applying medicines against mastitis, 55 farmers chose them on the basis of their own experience, 42 farms(57%) were treated more than 3 days. 41 farms(55%) dumped away the mastitis infected milk separately, 24 farms(32 %) were feeding and milking at the same time. 8. Fifty-six farms(76%) always washed and disinfected milking machines after milking. Farms using the milking machines at low, or variable vacuum pressures, or at the vacuum pressure, set at the moment of its installation were 31(42%), and farms that did not know pulsation ratio were 27(37%). Farms changing liners when they were torn 8(11%), 58 farms(78%) said they checked milking system when there were wrong with them, 31 farms(42%) changed milking hoses when they found out problems, and 42 farms(57%) cleaned vacuum and milking systems when they felt dirty. The SPC grade 1A of farms washing and sterilizing milking machines was 38% and farms only washing was 28%.

경남 남부지방에서 송아지설사병 원인체 바이러스 검출 조사

허정호 ( Jung Ho Heo ),조명희 ( Myung Heui Cho ),이국천 ( Kuk Cheon Lee ),박미남 ( Mi Nam Park ),조은정 ( Eun Jeong Cho ),최만수 ( Man Su Choi ),김충희 ( Chung Hui Kim ),강정부 ( Joung Boo Kang ),김의경 ( Eui Kyung Kim ),김종수 ( 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.3

Among calves` diseases, digestive diseases most frequently occur in Korea, and especially viral diarrhea is one of the most important diseases. This study was conducted to get some basic information for the control of the viral diarrhea in calves. The samples were obtained from 319 calves with clinical diarrhea from 195 farms in Gyeongnam south area (Gosung, Tongyung, Hadong) from June 2005 to August 2006. Viral detection was examined by polymerase chain reaction (PCR). Etiological viruses were detected from 171(53.6%) of 319 calves, and bovine rotavirus (BRV) were 130 (40.8%) and bovine viral diarrhea virus (BVDV) 41 (12.9%), and no coronavirus was confirmed. Statistical difference was found in BRV detection between summer (32.6%) and winter (57.7%). However there was no seasonal difference in BVDV. In detection rate of the calves under 19days, BRV was highest (55.1%), but BVDV lowest (5.1%). No big difference was in rate among herd size. However, BRV was lowest (26.8%) in the group over 51 heads, but BVDV was highest (19.5%) in the same.

경남 남부지방에서 사육 중인 송아지의 설사병에 관한 역학적 연구

허정호 ( Jung Ho Heo ),조명희 ( Myung Heui Cho ),이국천 ( Kuk Cheon Lee ),박미남 ( Mi Nam Park ),조은정 ( Eun Jeong Cho ),최만수 ( Man Su Choi ),김충희 ( Chung Hui Kim ),강정부 ( Joung Boo Kang ),김의경 ( Eui Kyung Kim ),김종수 ( 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.3

The present study was conducted to investigate the epidemiological characteristics such as isolation rate and antimicrobial drug susceptibility of etiological agents. The specimens (stool or intestine) were collected from 319 calves with clinical diarrhea from 195 farms in Gyeongnam south area (Gosung, Tongyung, Hadong) from June 2005 to August 2006. The isolation rate of Salmonella spp was higher in summer (8.4%) than in winter (4.8%) and the average was 7.2% (23/319 head). Some of Salmonella spp isolated were resistant to penicillin, oxytetracycline, tetracycline, and cephalexin (>90%), but some of them were suscep-tible to norfloxacin, ciprofloxacin, sulfamethoxazole/trimethoprim and amikacin(>30%). There was no statistical difference in the isolation rate of Eimeria spp between summer(48.9%) and winter(42.3%). For the evaluation of infection level of Eimeria spp oocyst per gram of feces(OPG) was examined, and severe, moderate and light infection level were 11.9%, 12.5% and 22.3%, respectively. In the isolation rates of Eimeria spp the calves under 19 days was lowerthan those over 60 days, but there was not different among herd size.

침투형 집수정의 우수유출 저감효과 분석을 위한 실시간 계측

이종국,허정호,박상구,Lee, Jong-Guk,Heo, Jeong-Ho,Park, Sang-Gu 한국수자원학회 2000 한국수자원학회논문집 Vol.33 No.1

돼지 분변 및 도체에서 분리한 대장균, 장구균의 항생제 내성율 조사

정귀옥 ( Kwi Ok Jeong ),허정호 ( Jung Ho Heo ),이종민 ( Jong Min Lee ),윤이란 ( I Ran Yun ),최유정 ( You Jeong Choi ),김종수 ( Jong Shu Kim ) 한국가축위생학회 2010 韓國家畜衛生學會誌 Vol.33 No.3

The present study was conducted to investigate isolation and antimicrobial resistance ratio of E. coli, E. faecium and E. faecalis from feces(150 samples) and carcasses (150 samples) on slaughtered pigs from 6 slaughterhouse of 13 cities in the Gyeongnam during the period from January 2009 to December 2009. Isolation ratio of E. coli from feces and carcasses were 98 (65.3%) and 110 (73.3%), respectively, and simultaneously, E. faecalis and E. faecium from feces and carcasses were isolated 21 (14%), 52(34.7%) and 18 (12%), 14 (9.3%), respectively. All E. coli isolated from feces and carcasses except cefepime (0%) and ceftiofur (0%) were exhibited 2.4~83.6% of resistance to teteracycline (83.6%), ampicillin (68.2%), streptomycin (60%), chloram-phenicol (53.8%) and cephalothin (2.4%). All E. faecalis isolated from feces and carcasses except penicillin(0%) and vancomycin (0%) were exhibited 2.7~80.8% of resistance to teteracycline (80.8%), quinupristin/dalfopristin (78%), erythromycin (56.1%), streptomycin (43.8%) and bacitracin (2.7%). All E. faecium isolated from feces and carcasses except gentamicin (0%), vancomycin (0%), florfenicol (0%), linezloid (0%) and bacitracin (0%) were exhibited 3.1~53.1% of resistance to rifampin (53.1%), erythromycin and tetracycline (25%), penicillin (15.6%), ciprofloxacin (9.3%), and streptomycin, chloramphenicol, and quinupristin/dalfopristin (3.1%). According to the heard size, resistance ratio of E. coli strains isolated from feces and carcasses in slaughtered pigs-breeding farms over 1,500 heard to tetracycline, ampicillin, streptomycin and chloramphenicol showed higher resistance ratio (1.0 ~16.8%) than those of farms-breeding under 1,500 heard. From the our results, we suggest that a few of antimicrobials were used in the Gyeongnam than the other cities.

항공사 승무원의 이직요인이 직무만족에 미치는 영향에 관한 연구

이정현(Jung-Hyun Lee),허정호(Heo Jeong Ho) 한국산학기술학회 2015 한국산학기술학회 학술대회 Vol.2015 No.1

본 연구는 승무원의 이직요인을 개인적 이직요인과 직무적 이직요인으로 분류하고 이러한 이직요인이 직무만족에 어떠한 영향을 미치는지 알아보고 지속적이고 만족스러운 직무환경을 조성하는 방법을 모색하는데 그 목적을 두고 있다. 연구결과 승무원의 개인적 이직요인 중 일, 가정 갈등에 대한 요인은 직무만족에 영향을 주고 있지 않으며, 경력개발 기회부족과 업무이직요인인 직무탈진화와 업무과부화는 직무만족에 영향을 미치는 것으로 나타났다. 이에 승무원의 직무만족을 높이고 이직률을 줄이기 위해서 자아실현 및 조직차원에서 성과향상상의 밑거름이 될 수 있는 경력개발 기회를 더 많이 부여하고, 대인 접촉이 많은 승무원의 정서적, 신체적 고갈상태가 오지 않도록 보다 세분화된 제도가 모색되어야 한다.