전이성 위암환자의 심부정맥혈전증에 대한 저분자량 헤파린 투여 사례

허수진,박찬혁,이상길,Su Jin Heo,Chan Hyuk Park,Sang Kil Lee 대한소화기암연구학회 2013 Journal of digestive cancer reports Vol.1 No.2

The relationship between malignancy and venous thromboembolism(VTE) has been well established. About 20% of all VTE cases are associated with cancer and thrombotic events are the second leading cause of death in cancer patients after death from cancer itself. Effective prophylaxis and treatment will reduce morbidity and may decrease overall mortality. We report a case of VTE in a patient with advanced gastric cancer who treated with low-molecular weighted heparin (LMWH). A 49-year-old man with heartburn was admitted to our hospital. On the endoscopic and radiologic imaging, the patient was diagnosed as an advanced gastric cancer with perigastric infiltration and liver metastasis. During the combination chemotherapy, he had pain and swelling of left lower leg. Doppler ultrasonography showed left posterior tibial venous thrombosis and pulmonary embolism CT showed thromboembolism in subsegmental pulmonary artery branch in right lower lobe. He was treated with LMWH, Dalteparin once daily via subcutaneous injection, and his symptoms was subsided.

병원 의료기기의 비용절감

허수진,Heo, Su-Jin 대한병원협회 1985 대한병원협회지 Vol.14 No.4

Antioxidant Activity of Enzymatic Extracts from Brown Seaweeds

허수진,이기완,송춘복,전유진,Heo, Su Jin,Lee, Gi Wan,Song, Chun Bok,Jeon, Yu Jin The Korean Society of Phycology 2003 ALGAE Vol.18 No.1

의료기기 관리 향상방안

허수진,Heo, Su-Jin 대한병원협회 1986 대한병원협회지 Vol.15 No.3

김이교(1764∼1832) 묘 출토 조복 연구

허수진(Heo Su-Jin),심연옥(Sim Yeon-Ok),금종숙(Keum Jong-Suk) 한복문화학회 2021 韓服文化 Vol.24 No.4

This study examines the jo-bok(government official’s ceremonial costume) excavated from Kim I-Gyo(1764∼1832) tomb from Yesan-gun, Chungcheongnam-do. The purpose of the study is to report new excavated relics of the jo-bok, and to reveal the manufacturing method and periodical characteristics of the Kim I-Gyo"s jo-bok. First, an investigation and analysis of the clothing construction, fabric composition,, and weaving characteristics were made. Next, Kim I-Gyo"s jo-bok characteristics are determined by comparing them with those of the mid-17th and mid-19th centuries. Kim I-Gyo"s jo-bok consists of a red outer robe, inner robe, ceremonial skirt, and back drapery. Fabrics used for jo-bok are three-end leno weave, thin silk tabby, satin, and silk tabby. The embroidery technique of back drapery is satin stitch, straight stitch, long and short stitch, outline stitch, knot stitch, padded stitch. Compared to the characteristics of artifacts from the same period, Kim I-Gyo"s jo-bok has typical characteristics of the 18th-century jo-bok and a transitional pattern of change. Kim I-Gyo"s robes are the only existing excavated artifacts that include inner robes and are notable for using three-end leno weave and thin silk as their main fabrics. In addition, Kim I-Gyo’s jo-bok is expected to be used in various research fields as literature, artifacts, and painting related to one person remain.

가시오가피 잎ㆍ뿌리ㆍ줄기ㆍ열매 추출물의 이화학적 특성 및 항산화 효과

Su-Jin Heo(허수진),Hee-Young Ahn(안희영),Min-Jeong Kang(강민정),Jae-Hong Lee(이재홍),Jae-Young Cha(차재영),Young-Su Cho(조영수) 한국생명과학회 2011 생명과학회지 Vol.21 No.7

가시오가피 잎, 뿌리, 줄기 및 열매의 수용성, 에탄올 및 메탄올 추출물의 생리활성 물질 분석과 항산화 활성 (DPPH free radical scavenging 활성, Cu/Fe-환원력, 간 조직 microsome 생체막 및 linoleic acid 과산화지질, Tyrosinase 저해활성)을 측정 하였다. 가시오가피 잎의 열수 추출물에서 추출 수율 16.04%, 폴리페놀 화합물 함량 2.67% 및 플라보노이드 함량 1.43%로 가장 높았다. 가시오가피 잎, 뿌리, 줄기 및 열매의 주요 미네랄은 K, Ca 및 Mg 이었다. DPPH free radical scavenging 활성, Cu/Fe-환원력, 간 조직 microsome 생체막 및 linoleic acid의 과산화 지질 측정에 의한 항산화 활성은 가시오가피 잎, 뿌리, 줄기 및 열매 모두에서 나타났으며, 시료 처리 농도 의존적으로 활성이 증가되는 것으로 나타났다. 이상의 실험 결과에서 가시오가피 잎, 뿌리, 줄기 및 열매 모두에서 높은 항산화 활성이 있었으며, 이는 폴리페놀 화합물과 플라보노이드와 같은 생리활성 성분을 많이 함유하고 있는 것과 깊은 관련성이 있는 것으로 향후 건강기능식품이나 기능성화장품의 천연 항산화제 소재 개발 관련 연구의 기초자료로 활용될 수 있을 것으로 사료되어 진다. The contents of bioactive and antioxidative activities (DPPH (α,α’-diphenyl-β-picrylhydrazyl), free radical scavenging activity, peroxidation of linoleic acid and rat hepatocyte microsome, and Fe/Cu reducing power, tyrosinase inhibition activity) were tested by in vitro experimental models using water, hot water, ethanol and methanol extracts of leaves (ASL), roots (ASR), stems (ASS) and fruits (ASF) from Acanthopanax senticosus. Hot water extract from ASL showed the highest extraction yield (16.04%) as well as highest contents of phenolic compounds (2.67%) and flavonoids (1.43%). Major minerals were K, Ca and Mg. In oxidation in vitro models using DPPH free radical scavenging activity, Fe/Cu reducing power, Fe²?/ascorbate-induced linoleic acid peroxidation by ferric thiocyanate and thiobarbituric acid (TBA) methods, tyrosinase inhibition activity and autooxidation of rat hepatic microsomes membrane, and antioxidative activities were strong in Acanthopanax senticosus. From these results, ASL extracts were shown to have the most potent antioxidative properties and contain the highest amounts of antioxidative compounds such as phenolic compounds and flavonoids. These results may provide the basic data to understand the biological activities of bio-active materials derived from leaves of Acanthopanax senticosus.

2단 모듈 전기차 배터리 케이스 구조에 관한 해석적 연구

허수진(Su-Jin Heo),김덕현(Deok-Hyun Kim),김동섭(Dong-Seob Kim),유경선(Kyung-Sun You),손성만(sung-Man Sohn),이종욱(Jong-Wook Lee),고건우(Gun-Woo Ko) 한국자동차공학회 2022 한국자동차공학회 지부 학술대회 논문집 Vol.2022 No.10

Bioactive Materials and Biological Activity in the Extracts of Leaf, Stem Mixture and Root from Angelica gigas Nakai

Jin Sun Heo(허진선),Jae Young Cha(차재영),Hyun Woo Kim(김현우),Hee Young Ahn(안희영),Kyung Eun Eom(엄경은),Su Jin Heo(허수진),Young Su Cho(조영수) 한국생명과학회 2010 생명과학회지 Vol.20 No.5

지리산 청정지역에서 재배되고 있는 참당귀의 생리활성 물질과 효능을 이용한 건강 기능성 식품 또는 화장품 소재 개발을 위한 기초연구의 일환으로 참당귀의 잎, 줄기 혼합물 및 뿌리의 추출방법에 따른 phenolic compounds, flavonoids, minerals, decursin 및 decursinol angelate 등의 생리활성 물질 분석과 항산화 활성 및 환원력을 측정하였다. 당귀 뿌리의 온수 추출물 수율은 21.89%로 가장 높았다. 페놀성 화합물 및 플라보노이드 함량은 참당귀잎, 줄기 혼합물의 에탄올 추출물에서 가장 높은 함량을 보였고, 참당귀 뿌리 보다는 잎, 줄기 혼합물에서 높았고, 수용성 추출물보다 에탄올 추출물에서 높았다. 미네랄함량은 참당귀 잎, 줄기 혼합물 및 뿌리 모두에서 K, Mg, Fe, Na, Ca, Mn, Zn 순으로 함유되어 있었다. HPLC 분석에 의한 참당귀 잎, 줄기, 뿌리의 decursin 및 decursinol angelate의 혼합 면적 비율은 각각 66.1%, 82.2%, 79.8%로 나타났으며, decursin은 13.0%, 37.6%, 47.1%로 뿌리에서 가장 높았고 decursinol angelate는 53.2%, 44.6%, 32.6%로서 잎에서 가장 높았다. Free radical scavenging 항산화 활성은 참당귀 잎, 줄기 혼합물 및 뿌리 각각의 열수 추출물에서 가장 높았으며, 뿌리보다는 잎, 줄기 혼합물의 모든 추출물에서 항산화 활성이 높았다. Fe 및 Cu 환원력은 참당귀 잎, 줄기 혼합물 및 뿌리의 온수, 열수 및 에탄올 추출물 순으로 높게 나타났으며, 참당귀 잎, 줄기 혼합물의 추출물이 뿌리 추출물 보다 높은 활성을 보였는데 이는 페놀성 화합물이나 플라보노이드 함량과 밀접한 관계를 보였다. Tyrosinase 저해 활성은 참당귀 잎, 줄기혼합물 및 뿌리의 열수 추출물에서 가장 높은 것으로 나타났다. 이상의 실험 결과 참당귀에탄올 추출물에서는 페놀성 화합물과 플라보노이드 함량 및 환원력이 높았으며, 열수 추출물에서는 항산화 효과가 높아 참당귀 유래의 생리활성물질과 그 활성을 이용한 제품 개발에 필요한 기초 자료를 제공해주는데 유용하게 사용될 수 있을 것으로 생각된다. The bioactive materials (phenolic compounds, flavonoids, minerals, decursin and decursinol angelate) and biological activities (DPPH [α,α'-diphenyl-β-picrylhydrazyl] free radical scavenging capability, reducing power, and tyrosinase activity) in the extracts of leaf, stem mixture (AGLS), and root (AGR) from Angelica gigas Nakai were examined by using water, hot water and ethanol solvent. The highest extract yield (21.89%) was found in the water extract of AGR. The highest concentrations of phenolic compounds and flavonoids in the ethanol extracts of AGLS and AGR were 14.99% and 14.79%. Major minerals of AGLS and AGR were K, Mg, Fe, Na and Ca. Decursin and decursinol angelate were the major ingredients of Angelica gigas, detected at 18.71 and 18.89 min of retention time by HPLC analysis, respectively. The highest concentrations of decursin and decursinol angelate in the Angelica gigas ethanol extract were found in root (41.7 ㎍/g ) and leaf (34.04 ㎍/g). The highest free radical scavenging activity was found in the hot water extracts of AGLS and AGR, and its activity was stronger in all extracts of AGLS than AGR. The highest reducing power was found in the ethanol extracts of AGLS and AGR and this was dependent on the sample concentration. The hot water extracts of AGLS and AGR revealed the highest inhibition activity on tyrosinase. Overall, these results may provide the basic data needed to understand the biological activities of bioactive materials derived from Angelica gigas.

멍게양식업의 구조변화와 경쟁력 확보방안

허수진(Su-Jin Heo),이남수(Nam-Su LEE),김대영(Dae-Young KIM) 한국수산해양교육학회 2018 水産海洋敎育硏究 Vol.30 No.3

열간조압연 공정에서의 폭 압하 공정시 슬래브의 변형 특성

허수진(Su-Jin Heo),이상호(Sang-ho Lee),변상민(Sang-Min Byun),박해두(Hae-do Park),이종빈(Jong-Bin Lee),김병민(Byung-Min Kim) 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.5

In general, final width of hot strip should be accomplished in this stage because width reduction of strip hardly appears during typical finishing mill. However, it is difficult to control the width of strip in the roughing mill process as the horizontal rolling of strip is subsequently performed after the vertical rolling. It is therefore important to obtain the deformation of rolling direction on strip width to minimize the width spread of strip during horizontal rolling after vertical rolling. Generally there is Sizing press type and Edger-roll type. The width reduction process in sizing press has small amount of width spread compared with the edger. However, productivity by the sizing press process is much lower than those of the edger. In this study, sizing press and Edger-roll process parameters in a sheet rolling mill were set at specified values and the effect of the change in these parameters on product quality and process performance were evaluated.