풍란과 나도풍란 재배시 단색 및 혼합 LED 광이 생장과 엽록소 함량에 미치는 영향

허경연,김건일,박소영 한국화훼학회 2018 한국화훼학회 정기총회 및 학술발표회 자료집 Vol.26 No.1

장애아동과 비장애 아동의 식습관 및 섭식 행동 비교

김은경,안성연,김은미,허경자 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.6

This study was conducted to compare the eating habits of disabled and non-disabled children in Seoul and Gangneung. Korea. Questionnaires about eating habits were answered by the children's parents and their teachers. The subjects of this study consisted of 146 disabled children (108 boys and 38 girls) from two special education schools and 241 non-disabled children (control group,120 boys and 121 girls) from two elementary schools in Seoul and Gangneung, respectively. The percentage of the children who required more than 30 minutes to eat was 11.3% in the disabled group and 2.5% in the non-disabled group. In the disabled group,44.0% ate excessive amounts of food or could not control their intake. The percentage of the children whose frequency of eating breakfast was less than 1 to 2 times per week was 21.0% in the disabled group and 9.7% in the non-disabled group. Also, 7.6% of the disabled group and 13.9% of the non-disabled group had snacks more than three times per day. The percentage of children who were able to eat by themselves was lower in the disabled group (47.9%) than in the non-disabled group (87.8%). Of the remainder of the disabled group,28.6% spilled food, and 14.3% needed the aid of others when picking up side dishes. The percentage of parents who worried about their children's eating an unbalanced diet was 48.5% in the disabled group and 41.8% in the non-disabled group. In addition, there were problems with eating behaviors in 22.7% in the disabled group, and with under-eating (15.9%) and with excessive intake of instant foods (16.8%) in the non-disabled group. These results suggest that the eating habits and eating behaviors of disabled children are different from those of non-disabled children. Thus, nutritional educational programs and educational materials for disabled children and their parents should be developed.

Comparison of Plasma and Brain Exposure Levels of Bis-pyridinium Oximes KR-22839 and KR-26256 with Asoxime and Obidoxime in Mice

이현명,안선주,이하연,임재민,조성희,Kamil Kuca,Kamil Musilek,한수봉,허경행,정영식 대한화학회 2019 Bulletin of the Korean Chemical Society Vol.40 No.1

김으로부터 Porphyra 334의 양산 및 분석법 밸리데이션에 관한 연구

장성주,이삭,허경연,이정훈,모상현 한국산학기술학회 2022 한국산학기술학회논문지 Vol.23 No.12

Laver comprises large amounts of mycosporine-like amino acids, one of the high-content substances being Porphyra 334. Since this compound reportedly exerts anti-aging effects such as anti-oxidant, wound healing, wrinkle improvement, and UV absorption, it is under constant research and development by cosmetic companies for varied applications as a cosmetic ingredient. However, to date, there is no commercialized Porphyra 334, and there is an unmet necessity to develop a technology for mass production. In this study, extraction was achieved under varied conditions to increase the yield of Porphyra 334, and the optimal solvent, time, and temperature conditions were confirmed. Additionally, a high content of Porphyra 334 was purified from laver extract using liquid chromatography. A quantitative analysis method of Porphyra 334 was devised, and the analytical method was validated by evaluating the specificity, linearity, precision, accuracy, and stability. In conclusion, our study achieved optimizing the bulk extraction process for Porphyra 334. Moreover, the analysis method was established and validated for future industrial applications. 김에는 다양한 종류의 미코스포린 유사 아미노산이라는 물질이 함유되어 있으며 이러한 물질들 중 특히 높은함량으로 함유된 물질 중 하나가 바로 Porphyra 334이다. 항산화, 상처 치유, 주름 개선, 자외선 흡수 등 다양한 효능이확인된 이 물질은 화장품 원료로 사용하기 위해 많은 화장품 회사들이 연구 개발 중에 있다. 이를 위해서는 우선Porphyra 334의 원료 확보가 필요한 실정인데, 현재까지는 대량 생산 방법이 정립되어 있지 않다. 본 연구에서는 김에서부터 Porphyra 334를 산업적으로 정제·생산하는 데 있어 생산 수율을 높이기 위한 다양한 방법의 추출을 수행하였다. 최적의 처리 방법을 찾고자 용매, 시간 및 온도와 같은 여러 조건을 확인하여 최적의 추출 공정을 찾았고, 확립한방법으로 대량 추출한 후 액체 크로마토그래피를 통해 Porphyra 334의 단일 화합물을 정제 및 생산하였다. 이렇게생산된 Porphyra 334를 이용하여 정량분석에 필요한 분석 방법을 연구하였고, 분석법 밸리데이션을 실시하였으며, 그결과 특이성, 직선성, 정밀성, 정확성, 안정성이 확보된 분석법을 확립함으로써 분석법 검증을 완료하였다. 결론적으로본 연구를 통해 확인된 대용량 추출 공정을 거쳐 Porphyra 334를 생산하였고 분석법까지 확립함으로써 본 생산 공정은산업적으로 적용이 가능함을 확인하였다.

유기인제 중독의 복합예방제로서의 Procyclidine과 Physostigmine의 일반약리작용

이선애(Sun Ae Lee),조순옥(Soon Ock Cho),이보영(Bo Young Lee),반주연(Ju Yeon Ban),조영(Young Cho),허경행(Gyeung-Haeng Hur),김왕수(Wang-Soo Kim),김지천(Jee-Cheon Kim),김윤배(Yun-Bae Kim),성연희(Yeon Hee Seong) 한국실험동물학회 2005 Laboratory Animal Research Vol.21 No.3

General pharmacological properties of procyclidine and physostigmine, as a combinational prophylactic regimen for organophosphate poisoning, were investigated in experimental animals and in vitro test system. Procyclidine and physostigmine were administerd by subcutaneous injection or miniosmotic pumps for sustained release. Procyclidine had no effects on general behavior, spontaneous motor activity, pentobarbital sleeping time, motor coordination and normal body temperature at the doses of less than 30 ㎎/㎏ or 1728 ㎍/㎏/hr. Gastric secretion and intestinal motility in rats were not influenced by the sustained release of procyclidine at dose of 1296 ㎍/㎏/hr. Procyclidine up to 40 ㎎/㎏ did not change the mean arterial blood pressure and heart rate in conscious rats. Procyclidine had no effect on the respiratory rate at the same doses when given to anesthetized rats. In in vitro experiments, procyclidine at the concentration of more than 0.1 and 1 ㎎/ℓ showed significant inhibitory action on the acetylcholine-and histamine-induced contractions, respectively, in the isolated ileum of guinea-pig. In the isolated guinea-pig tracheal muscle, procyclidine did not affect the histamine-induced contractions at the dose of 5 ㎎/ℓ, but showed partial inhibition on the acetylcholine-induced contractions at the doses of 3 and 5 ㎎/ℓ. Physostigmine at the concentration of 0.05 ㎎/㎏ or 36 ㎍/㎏/hr neither produced significant change of the normal physiological activity of rats, nor completely recover the inhibitory effect of procyclidine on the gastrointestinal tract. Based on these results, it was concluded that procyclidine and physostigmine did not induce marked adverse effects in experimental animals except the significant inhibitory effect on the gastrointestinal system.

SDE에서 이력 관리를 위한 시간관계 매크로의 구현

허경(Kyung Heo),이종연(Jong Yun Lee),류근호(Keun Ho Ryu) 한국정보과학회 1999 정보과학회 컴퓨팅의 실제 논문지 Vol.5 No.5

SDE^(TM)(Spatial Database Engine)는 ESRI 회사에서 개발한 클라이언트-서버 구조의 공간 데이타베이스로서 빠르고 효율적인 공간 연산의 수행과 대규모의 공간 데이타 집합을 취급하며 다양한 공간 연산과 공간관계 매크로를 지원한다. 아울러 공간상의 지형객체는 공간 또는 속성 변경에 의한 이력 데이타가 발생하지만, SDE와 같은 기존의 공간 도구는 지형객체의 스냅샷 정보만을 취급하므로 시간의 흐름에 따른 이력 데이타는 물론 이력질의를 지원하지 못한다. 따라서, 이 논문에서는 SDE를 이용한 지리정보 시스템의 이력질의 지원을 목표로 시공간 데이타 모델의 정립을 비롯하여 시공간 탐색 조건식의 생성 알고리즘과 시간관계 매크로의 구현 알고리즘을 제시한다. 구현된 시공간 데이타 모델과 시간관계 매크로 확장은 지리정보 시스템에서 시간변이 지형객체의 이력 데이타 관리와시간관계 매크로에 의한 이력질의를 수행할 수 있다. The Spatial Database Engine(SDE^(TM)) developed by Environmental Systems Research Institute, Inc. is a spatial database that employs a client-server architecture incorporated with a set of software services to perform efficient spatial operations and to manage large, shared and geographic data sets. It currently supports a wide variety of spatial search methods and spatial relationships determined dynamically Spatial objects in the space world can be changed by either non-spatial operations or spatial operations. Conventional geographical information systems(GISs) did not manage their historical information, however, because they handle the snapshot Images of spatial objects in the world. In this paper we propose a spatio-temporal data model and an algorithm for temporal relationship macro which is able to manage and retrieve the historical information of spatial objects. The proposed spatio-temporal data model and its operations can be used as a software tool for history management of time-varying objects in database without any change.