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박성학,박주현,신완식,김관형,한현복,김양리,강문원 대한감염학회 1990 감염 Vol.22 No.3
Clinical efficacy and safety of cefixime, a new oral cephem antibiotics, were evaluated in 30 patients with respiratory tract infection. Cefixime was administered to 30 cases consisting of 4 cases of acute tonsillitis, 16 cases of pneumonia (8/16 have underlying chronic lung disease) and 10 cases of acute exacerbation of chronic lung diseases (3 with bronchiectasis, 2 with bronchial asthma and 5 with chronic obstructive lung diseases), at daily dosis of 200~400㎎ for 5~21 days by oral route. Clinical efficacy was evaluated to be excellent in 11 cases, good in 13 cases, fair in 5 cases and poor in 1 case. Thus cefixime was effcetive in 24 of 30 cases in total with a rate of effectiveness of 80%. Effectiveness of cefixime was 100% (12/12) in acute disease, but 66.7%(12/18) in chronic or complicated disease. 16 microorganisms were isolated from 13 cases. 10 cases were eradicated, 2 cases were persisted and 1 case was superinfected with P. aeruginosa. Adverse resactions were found in 3 cases: 1 with eosinophilia, 1 with anorexia and 1 with eosinophilia and skin rash to whom cefixime was discontinued. In conclusion, cefixime is useful oral drug for the empirical treatment of mild to moderate respiratory tract infection.
박동준,김성수,김부성,심규식,백남종,한현복,강동헌,서정민 대한내과학회 1991 대한내과학회지 Vol.41 No.5
The term $quot;biloma$quot; was introduced in 1979 by L. Gould and A. Patel to describe a loculated collection of bile located outside the biliary tree. The underlying causes are iatrogenic, traumatic, and spontaneous rupture of the bile duct system. The diagnostic methods are clinical history and physical examination, ultrasound, computered tomography, HIDA scintigram, and character of the material obtained by aspiration. Pecutaneous drainage is an effective form of therapy that often eliminates the need for surgical drainage. We experienced a case of biloma after percutaneous transhepatic biliary drainage in a patient with extrahepatic biliary obstruction due to advanced gallbladder carcinoma and present a report with a review of the literature.
박동준,강동헌,조철수,김호연,심규식,홍연식,김동집,한현복 대한내과학회 1992 대한내과학회지 Vol.43 No.3
Reflex sympathetic dystrophy syndrome (RSDS) is characterized by pain and tenderness of a distal extremity accompanied by signs and symptoms of vasomotor instability, trophic skin changes and rapid development of bony demineralization. It has been associated with a variety of pathologic conditions and there have been a few case reports of this syndrome as a kind of paraneoplastic manifestation of underlying malignancy. We report two cases of RSDS associated with malignant lymphoma and adenocarcinoma of the lung, respectively. A case with malignant lymphoma was completely cured and the other case was expired one year later after diagnosis. It is necessary to detect the underlying cause associated with malignancy in case of idiopathic RSDS and early detection of malignancy seems to be benefit in tumor-specific thrapy and perhaps improve the prognosis in some cases.
정규원(Kyu Won Chung),선희식(Hee Sik Sun),정인식(In Sik Chung),양진모(Jin Mo Yang),심상인(Sang In Shim),최명규(Myung Gyu Choi),한현복(Hyun Bok Han),정홍량(Hong Ryang Jeong),이재학(Jae Hak Lee),강창석(Chang Suck Kang) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.3
Recent advent of non-surgical treatment for gallstones desires accurate in vivo analysis of chemical composition to select optimal candidate. As preliminary work, we undertook in vitro CT examimation of the surgically removed 53 gallstones and compared CT pattern with chemical compsotion. Those results were correlated with in vitro lithotripsy of the gallstones. The CT appearances were classified as follows: Laminated (43%), dense (32%), rimmed (11%), isodense (8%) and faint (6%). Dense pattern contains high calcium content. As CT density increased, calcium content increased, but cholesterol content decreased proportionslly. The number of shock waves to breakdown the gallstone ]ess than 2 mm in size, has increased as stone volume and cholesterol content increases but did not have any correlation with calcium content level. As a result, the CT exmination is very sensitive to detect small amount of calcium content in gallstones and CT pattern and density of the gallstones are well correlated with chemical compsotion and therefore in vivo CT exmination for ESWL candidate is desirable.