http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
한소라,Young-Ki Chung,Mi Ran Kim,Hanbyul Lee,Yu Jin Kim,,장형윤,서수연 대한수면학회 2018 sleep medicine research Vol.9 No.1
Background and Objective Females with history of sexual violence report a high percentage of insomnia. Guilt is a common symptom among this group. This study investigated differences in trauma-related guilt cognition between females of sexual violence with high or low symptoms of insomnia. Methods Participants were 43 females who reported having a history of sexual violence (mean age 26.56±7.81). All participants completed questionnaires about insomnia symptoms (Insomnia Severity Index, ISI), Posttraumatic stress disorder (PTSD) symptoms (PTSD Symptom Scale Self-Report), trauma-related guilt (Trauma-related Guilt Inventory, TRGI), depression (Beck Depression Inventory) and trauma-related information. The TRGI is consisted by global guilt, distress and guilt cognitions. Guilt cognitions can further be divided into Hindsight-Bias/Responsibility, Wrongdoing, and Lack of Justification subscales. Analyses were conducted using Pearson’s correlation coefficient and analysis of covariance. Results Results indicated ISI scores were significantly positively associated with PSS scores (r = 0.620, p < 0.01) and the distress subscale of the TGRI (r = 0.488, p < 0.01), and negatively associated with guilt cognitions (r = −0.423, p < 0.01). 53.5% (n = 23) of the sample met criteria for clinical insomnia using ISI cut-off scores of 15. Participants in the insomnia group scored significantly lower in overall guilt cognitions (p < 0.001) and significantly higher in distress (p = 0.001) than the non-insomnia group after controlling for depression. Among the subscales of guilt cognitions, hindsight-bias/responsibility was significantly lower in the insomnia group (p < 0.001). Conclusions Guilt can sometimes be adaptive in trauma patients as it may work as a catalyst in cognitively processing their trauma. Our results indicate that individuals with insomnia report lower guilt cognition. This may subsequently interfere with their ability to process the traumatic experience and effectively cope with their situation.
표면근전도 모니터링을 위한 슬리브 일체형 니트 전극 개발
한소라,김혜림,임대영,정원영 한국섬유공학회 2022 한국섬유공학회지 Vol.59 No.6
Wearable biosignal monitoring systems are being developed in various fieldssuch as healthcare, fitness, and military industries. Due to its convenience, the leg sleeveintegratedwith embedded sEMG electrodes can be worn unconsciously in daily life,enabling continuous measurement and collection of biological signals. In this study, theknitting structure, electrode diameter, the amount of conductive yarn required, the coefficientof friction, the electrical resistance, the skin-electrode impedance, and the signal tonoise(SNR) were measured to optimize the knit based sEMG electrodes in the sleeve. Theresults indicated that plain stitch was confirmed to be an economically efficient knittingprocess because the production time is shorter and the amount of conductive yarn perunit area is smaller than other stitch structures. In addition, the biosignal collection performanceof the knitted electrode was slightly lower than that of the conventional Ag-Ag/Cldisposable wet electrode, and an electrode with a plain stitch diameter of 20 mm showedthe highest value of 0.31±0.02 mV in the state of muscle activation. It suggests that it ispossible to develop knitted electrodes for biosignal monitoring system.
Phenotypic and functional dissection of myeloid-derived suppressor cells
한소라,양영 한국응용생명화학회 2016 Applied Biological Chemistry (Appl Biol Chem) Vol.59 No.3
Myeloid-derived suppressor cells (MDSCs) are originated and differentiated population from common hematopoietic progenitor cells. Generally, in the late stage of inflammation, MDSCs differentiation and expansion are promoted to suppress the over-activated immune system so that the immune system can maintain the homeostasis. Recently, it has been revealed that MDSCs accumulate in cancer patients and tumor-bearing experimental animals, and these tumor-derived MDSCs suppress anti-tumor immunity by secreting immunosuppressive cytokines including reactive oxygen species and inducible nitric oxide synthase. This fact prompts scientists to shed light on MDSCs as significant targets for anti-cancer immunotherapy. However, due to morphological, phenotypic, and functional heterogeneities of MDSCs, it is not easy to develop therapeutic strategies targeting MDSCs. In this review, we will summarize recent progress on defined subsets of MDSCs and their strategies to suppress T cellmediated anti-tumor immunity.