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李暎美,朱英愛,表成恩 성신여자대학교 생활문화연구소 1988 生活文化硏究 Vol.2 No.-
This is a translation Empress Inhyomun's Naehun(仁孝文皇后 內訓) into Korean. Following part Ⅰ, part Ⅱis deal with the sections of contents as follows. Chapter 11. Kyung Hyun Bun(景賢範) Chapter 12. Relations between Parents and Children Chapter 13. Marital relations Chapter 14. Relations between Parents-in-low and one's son's wife Chapter 15. Ancestral rites Chapter 16. Education of offspring Chapter 17. Peace within a family Chapter 18. Liberty Chapter 19. Apprehension Chapter 20. Deal with one's a maternal relation
표주연,홍순원,김지섭,최성은,신은아,양석우,박정수,김석모 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.1
We describe herein histologic, immunohistochemical, and molecular findings and clinical manifestations of a rare case of an extremelywell differentiated papillary thyroid carcinoma (EWD-PTC). Similarly, it is also difficult to diagnose follicular variant papillarythyroid carcinoma (FVPTC), whose diagnosis is still met with controversy. A recently reported entity of well-differentiated tumor of uncertain malignant potential (WDT-UMP) is added to the diagnostic spectrum harboring EWD-PTC and FVPTC. We reportthis case, because EWD-PTC is different from FVPTC in its papillary architecture, and also from WDT-UMP in its recurrence and metastatic pattern. These morphologically deceptive entities harbored diagnostic difficulties in the past because the diagnosisdepended solely on histology. However, they are now diagnosed with more certainty by virtue of immunohistochemical and molecularstudies. We experienced a case of EWD-PTC, which had been diagnosed as adenomatous hyperplasia 20 years ago and manifested recurrence with lymph node (LN) metastasis 7 years later. After another 7 years of follow-up, a new thyroid lesion had developed, diagnosed as FVPTC, with LN metastasis of EWD-PTC. One year later, the patient developed metastatic FVPTC in the skull. Immunohistochemically, the EWD-PTC was focally positive for CK19, negative for galectin-3, and focally negative for CD56. Molecular studies revealed BRAF-positivity and K-RAS negativity. The FVPTC in the left thyroid showed both BRAF and K-RAS negativity. In conclusion, EWD-PTC and FVPTC share similar histologic features, but they are different tumors with different molecularbiologic and clinical manifestations. A large cohort of EWD-PTC should be included in further study.
표주연,홍순원,최성은,신은아,구자승 대한병리학회 2017 Journal of Pathology and Translational Medicine Vol.51 No.5
Background: When differential diagnosis is difficult in thyroid follicular lesions with overlapping histological features, the immunohistochemical staining can help confirm the diagnosis. We aimed to evaluate the effectiveness of rapid immunohistochemical stains of CD56 and cytokeratin 19 on frozen sections of thyroid follicular lesion and explore the possible gains and limitations of the practice. Methods: Eighty-six nodules of 79 patients whose intraoperative frozen sections were selected as the control group, and 53 nodules of 48 patients whose intraoperative frozen sections were subject to rapid immunohistochemistry were selected as the study group. Results: Five nodules (6%) in the control group were diagnosed as follicular neoplasm and six nodules (7%) were deferred. In the study group, six nodules (11%) were follicular neoplasm and none were deferred. Three nodules (4%) in the control group showed diagnostic discrepancy between the frozen and permanent diagnoses, but none in the study group. The average turnaround time for the frozen diagnosis of the control group was 24 minutes, whereas it was 54 minutes for the study group. Conclusions: Intraoperative rapid immunohistochemical stains significantly decreased the diagnostic discrepancy in this study. Considering the adverse effects of indefinite frozen diagnosis or discrepancy with permanent diagnoses, the intraoperative rapid immunohistochemical stain can help to accurately diagnose and hence provide guidance to surgical treatment.
리플로우 횟수가 ENIG/Sn-3.5Ag/ENIG BGA 솔더 조인트의 기계적, 전기적 특성에 미치는 영향
성지윤,표성은,구자명,윤정원,노보인,원성호,정승부,Sung, Ji-Yoon,Pyo, Sung-Eun,Koo, Ja-Myeong,Yoon, Jeong-Won,Noh, Bo-In,Won, Sung-Ho,Jung, Seung-Boo 한국마이크로전자및패키징학회 2009 마이크로전자 및 패키징학회지 Vol.16 No.1
본 연구에서는 electroless nickel / immersion gold (ENIG) 처리된 printed circuit board (PCB)를 무연 솔더인 Sn-3.5(wt%)Ag로 접합하였다. 리플로우 횟수를 1회부터 10회까지 다양하게 하여 리플로우 횟수가 증가함에 따른 솔더 접합부의 기계적, 전기적 특성의 변화에 대해 연구하였다. 접합부의 미세 조직 관찰을 위해 접합부 단면을 폴리싱 하여 금속간 화합물의 두께를 측정하고 종류를 분석하였다. 접합부의 기계적 특성을 평가하기 위해서 die 전단 시험을 하였는데, 리플로우 횟수가 4-5회일 때까지 전단 강도 값이 증가하다가 5회 이후로 감소하였다. 전기적 특성을 알아보기 위해 전기 저항 값을 측정하였는데, 리플로우 횟수가 증가할수록 접합부의 전기 저항 값은 점점 증가하였다. In this study, solder joints were made with Sn-3.5Ag (wt%) solder ball. Electroless nickel / immersion gold (ENIG) printed circuit board (PCB) substrates were employed in this work. The mechanical and electrical properties were measured as a function of the number of reflow. Die shear strength was measured with increasing reflow number. Until the forth or fifth reflow, shear force increased and after the fifth reflow the shear force of die decreased. The electrical resistivity of solder joint linearly increased with increasing reflow number.
Sn-3.5Ag BGA 패키지의 기계적,전기적 특성에 미치는 PCB표면 처리
성지윤 ( Ji Yoon Sung ),표성은 ( Sung Eun Pyo ),구자명 ( Ja Myeong Koo ),윤정원 ( Jeong Won Yoon ),신영의 ( Young Eui Shin ),정승부 ( Seung Boo Jung ) 대한금속재료학회 ( 구 대한금속학회 ) 2009 대한금속·재료학회지 Vol.47 No.4
The mechanical and electrical properties of ball grid array (BGA) solder joints were measured, consisting of Sn-3.5Ag, with organic solderability preservative (OSP)-finished Cu pads and Electroless Nickel/Immersion Gold (ENIG) surface finishes. The mechanical properties were measured by die shear test. When ENIG PCB was upper joint and OSP PCB was lower joint, the highest shear force showed at the third reflow. When OSP PCB was upper joint and ENIG PCB was lower joint, the highest shear force showed at the forth reflow. For both joints, after the die shear results reached the highest shear force, shear force decreased as a function of increasing reflow number. Electrical property of the solder joint decreased with the function of increasing reflow number. The scanning electron microscope results show that the IMC thickness at the bonding interface gets thicker while the number of reflow increases.