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식물세포배양에 의한 항암제 Paclitaxel의 대량 생산
최형균,손주선,나광휘,홍승서,박연성,송재영,Choi, Hyung-Kyoon,Son, Joo-Sun,Na, Gwang-Hwee,Hong, Seung-Suh,Park, Yeon-Seung,Song, Jai-Young 한국식물생명공학회 2002 식물생명공학회지 Vol.29 No.1
Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The paclitaxel-Genexol$^{TM}$-is commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.
The Application of Metabolomics to Processed Traditional Chinese Medicine
Xue Jiang,최형균,Il-Hwan Oh,이슬기 한국응용생명화학회 2013 Applied Biological Chemistry (Appl Biol Chem) Vol.56 No.5
Processing technologies, which are required in the production of traditional Chinese medicine (TCM), has garnered attention in recent years. To address challenges associated with processed TCM and to promote its development in academia and industries, the application of metabolomics was introduced in this review, which primarily focuses on exploring TCM theories,identification of discovered compounds, and the evaluation and quality control of TCM through metabolomics. Thus metabolomics could be a powerful method for the TCM processing industry.
Lipids in Ginseng (Panax ginseng) and Their Analysis
김소현,김석영,최형균 한국생약학회 2018 Natural Product Sciences Vol.24 No.1
Ginseng (Panax ginseng) is recognized as one of the most valuable medicinal herbs in Asia and it contains diverse phytochemicals that contribute to its pharmacological effects. Although lipids represent a major component of ginseng, ginseng lipids are still far from being fully explored. This review is focused on ginseng lipid components and methodologies of their analysis. The ginseng lipid compounds were categorized according to the structural features of each lipid class. This basic information on ginseng lipid components and the analysis methods will be applicable to authentification or quality control of ginseng products, and development of lipid-based pharmaceuticals and nutraceuticals from ginseng.