난소임신에 대한 임상적 연구

최지미,김수용,배혜경,조성진,오세현,박인서 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.9

통합탐구 단원에 대한 초등학교 교사들의 인식과 지도 실태

최지미 ( Jimi Choi ),박다혜 ( Dahye Park ),박종욱 ( Jongwook Park ),박종석 ( Jongseok Park ) 한국과학교육학회 2016 한국과학교육학회지 Vol.36 No.5

이 연구는 2009 개정 교육과정 5∼6학년 과학 교과서에 새롭게 제시된 통합탐구 단원에 대한 초등학교 교사들의 인식과 지도 실태를 조사하여 통합탐구 단원 구성과 지도의 개선 방안을 모색하고자 하였다. 이를 위해 탐구지도와 관련된 기존 설문지를 수정, 보완하여 통합탐구 단원을 지도한 경험이 있는 교사들에게 설문을 실시해서 응답내용을 분석하였다. 그 결과, 교사들은 통합탐구과정 지도의 중요성에 대해 긍정적으로 인식하고 있었다. `통합탐구능력 습득 및 발달, 과학 학습의 전이, 자유탐구 실행` 측면에서 교사들의 통합탐구 단원의 적용 효과에 대한 인식은 긍정적이었으며 그 이유로 `통합탐구과정 학습을 위한 별도의 시간 확보, 후속 학습에서의 활용, 자유탐구 활동에서 통합탐구과정 적용의 용이함`을 들었다. 반면에 교사들은 `통합탐구과정의 분절적 학습, 통합탐구 단원과 다른 단원 간의 연계성 부족, 학생의 호기심 유발이 어려운 교과서 내용 구성`을 이유로 통합탐구 단원의 효과에 대해 부정적인 의견을 제시하기도 했다. 또한 통합탐구 단원의 지도 실태에 대한 조사를 통해 많은 교사들이 통합탐구과정 지도 시 교과서 내용을 그대로 따르는 것을 확인하였다. 교사들이 통합탐구 단원 지도 시 어려움을 가장 크게 겪는 과정은 문제인식이었으며 그 다음으로 가설설정, 변인통제, 자료변환 및 자료해석, 일반화, 결론도출 순이었다. 교사들이 어려움을 겪는 이유는 `학생들의 호기심·경험·이해력 부족, 교사의 전문성 부족, 교과서 구성의 한계 및 학습 시간 부족` 등으로 나타났다. 이러한 연구 결과는 통합탐구 단원의 개선 및 통합탐구과정 지도 관련 교사 전문성 제고를 위한 노력이 필요함을 시사한다. The `Integrated Inquiry` unit is a new addition in the 5th∼6th grade science textbooks, and was developed for the 2009 revised national curriculum. The unit deals with six integrated inquiry process skills: problem cognition, formulating hypotheses, controlling variables, transforming and interpreting data, drawing results, and generalization. The purpose of this study is to investigate the perceptions and the teaching practices of elementary school teachers on this unit in their school curriculum and where improvements can be made. Data was collected from questionnaires filled out by 92 elementary school teachers. The results are as follows: First, teachers do have a positive perception on the importance of teaching integrated process skills. Second, with that being true, this unit ended up receiving both positive and negative reviews by teachers. This research found that there were good and bad responses on the educational aspects of this unit in three particular areas: dealing with the development of integrated inquiry process skills, facilitating science learning in other units, and implementing open inquiry. Third, teachers have difficulties particularly in problem cognition, formulating hypotheses, controlling variables, transforming and interpreting data, generalization, and drawing results. There is a lack of student understanding as well as a lack of professionalism for teachers on this unit, and many issues related to the composition of the textbook. This study may have important implications for making improvements in this unit and teaching integrated process skills.

간장의 제조방법에 따른 품질 특성 비교 연구

최지미(Ji-Mi Choi),이춘복(Chun-Bok Lee),김학선(Hak-Seon Kim) 한국조리학회 2016 한국조리학회지 Vol.22 No.2

Time to Reach Target Glycosylated Hemoglobin Is Associated with Long-Term Durable Glycemic Control and Risk of Diabetic Complications in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A 6-Year Observational Study

김경진,최지미,배재현,김경진,류혜진,서지아,김난희,최경묵,백세현,김신곤,김남훈 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.3

Background: To evaluate the association of time to reach the target glycosylated hemoglobin (HbA1c) level with long-term durable glycemic control and risk of diabetic complications in patients with newly diagnosed type 2 diabetes mellitus (T2DM). Methods: In a longitudinal observational cohort, 194 patients with T2DM newly diagnosed between January 2011 and March 2013 were followed up over 6 years. Patients were classified according to the time needed to reach the target HbA1c (<7.0%): <3, 3 to 6 (early achievement group), and ≥6 months (late achievement group). Risks of microvascular complications including diabetic retinopathy, nephropathy, and neuropathy as well as macrovascular events including ischemic heart disease, ischemic stroke, and peripheral arterial disease were assessed by multivariable Cox proportional hazards analysis. Results: During a median follow-up of 6.53 years, 66 microvascular and 14 macrovascular events occurred. Maintenance of durable glycemic control over 6 years was more likely in the early achievement groups than in the late achievement group (34.5%, 30.0%, and 16.1% in <3, 3 to 6, and ≥6 months, respectively, P=0.039). Early target HbA1c achievement was associated with lower risk of composite diabetic complications (adjusted hazard ratio [HR, 0.47; 95% confidence interval [CI], 0.26 to 0.86 in <3 months group) (adjusted HR, 0.50; 95% CI, 0.23 to 1.10 in 3 to 6 months group, in reference to ≥6 months group). Similar trends were maintained for risks of microvascular and macrovascular complications, although statistical significance was not reached for macrovascular complications. Conclusion: Early target HbA1c achievement was associated with long-term durable glycemic control and reduced risk of diabetic complications in newly diagnosed T2DM.

Risk and Risk Factors for Postpartum Type 2 Diabetes Mellitus in Women with Gestational Diabetes: A Korean Nationwide Cohort Study

최미진,최지미,Chae Weon Chung 대한내분비학회 2022 Endocrinology and metabolism Vol.37 No.1

Background: There are differences in risk and risk factor findings of postpartum type 2 diabetes mellitus (T2DM) after gestational diabetes depending on study design and subjects of previous studies. This study aimed to assess these risk and risk factors more accurately through a population-based study to provide basic data for prevention strategies. Methods: This open retrospective cohort included data of 419,101 women with gestational diabetes and matched 1,228,802 control women who delivered between 2004 and 2016 from the South Korea National Health Information Database of the National Health Insurance Service. Following 14 (median 5.9) years of follow-up, the incidence and hazard ratio (HR) of postpartum T2DM were evaluated using Kaplan-Meier curves and Cox proportional regression models. Results: The incidence and HR of postpartum T2DM in women with gestational diabetes (compared to women without gestational diabetes) after the 14-year follow-up was 21.3% and 2.78 (95% confidence interval [CI], 2.74 to 2.82), respectively. Comorbid obesity (body mass index [BMI] ≥25 kg/m2) increased postpartum T2DM risk 7.59 times (95% CI, 7.33 to 7.86). Significant risk factors for postpartum T2DM were fasting glucose level, BMI, age, family history of diabetes, hypertension, and insulin use during pregnancy. Conclusion: This population-based study showed higher postpartum T2DM risk in women with gestational diabetes than in those without, which was further increased by comorbid obesity. BMI and fasting glucose level were important postpartum risk factors. The management of obesity and glycemic control may be important strategies to prevent the incidence of diabetes after delivery.

부인과영역에서 복강경의 진단적 가치

주원식,최지미,홍혜경,배혜경,박찬용,박인서 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.3

Time to Reach Target Glycosylated Hemoglobin Is Associated with Long-Term Durable Glycemic Control and Risk of Diabetic Complications in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A 6-Year Observational Study (Diabetes Metab J 2021;45:368-78)

김경진,최지미,배재현,김경진,류혜진,서지아,김난희,최경묵,백세현,김신곤,김남훈 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.4

임신중 합병된 난소암 1례

김수용,최지미,심재철,배혜경 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.8

Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea

김지원,홍남기,최지미,문주형,김의현,이은직,김신곤,구철룡 대한내분비학회 2023 Endocrinology and metabolism Vol.38 No.6

Background: Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods: We used the Korean nationwide claims database from 2009 to 2019. A total of 931 patients with acromegaly who had never used an osteoporosis drug before and were treated with surgery alone were selected as study participants, and a 1:29 ratio of 26,999 age- and sex-matched osteoporosis drug-naïve controls without acromegaly were randomly selected from the database. Results: The mean age was 46.2 years, and 50.0% were male. During a median follow-up of 54.1 months, there was no difference in the risks of all, vertebral, and non-vertebral fractures between the acromegaly and control groups. However, hip fracture risk was significantly higher (hazard ratio [HR], 2.73; 95% confidence interval [CI], 1.32 to 5.65), and non-hip and non-vertebral fractures risk was significantly lower (HR, 0.40; 95% CI, 0.17 to 0.98) in patients with acromegaly than in controls; these results remained robust even after adjustment for socioeconomic status and baseline comorbidities. Age, type 2 diabetes mellitus, cardio-cerebrovascular disease, fracture history, recent use of acid-suppressant medication, psychotropic medication, and opioids were risk factors for all fractures in patients with acromegaly (all P<0.05). Conclusion: Compared with controls, patients surgically treated for acromegaly had a higher risk of hip fractures. The risk factors for fracture in patients with acromegaly were consistent with widely accepted risk factors in the general population.

주요 신경계질환의 항우울제 처방 패턴: 2017년 제도 변경 이전

박윤아,백은선,최지미,이준영,이수현,박건우 대한신경과학회 2019 대한신경과학회지 Vol.37 No.2

Background: It is well known that patients with neurological disorders are vulnerable to depression. However, in Korea, National Health Insurance services had banned non-psychiatrists from prescribing antidepressants for more than 2 months until January 2017. Now, neurologists are able to prescribe antidepressants to patients with only four neurological disorders. Due to this recent change in national health insurance policy, there will be a large change in the prescription pattern of antidepressants. In this study, we performed an analysis of antidepressant prescription patterns in Korea prior to this recent policy change. Methods: The source population of this retrospective cohort study is the Health Insurance Review & Assessment Service database. We analyzed the claim database for patients who have one of four major neurologic disorders and had healthcare documentation submitted by healthcare providers between January 1, 2011 and December 31, 2016. Results: During 2012-2016, antidepressant prescription rates of 6.21% (127,192 of a total 2,048,165 patients), 9.93% (81,861 out of 824,290), 10.12% (173,582 of 1,714,776), and 13.36% (48,530 of 363,347) were found for cerebrovascular disease, epilepsy, dementia, and Parkinson’s disease respectively. The most frequently prescribed antidepressant in cerebrovascular disease and epilepsy was tricyclic antidepressants (TCAs). In Parkinson’s disease and dementia, the most frequently used antidepressant was selective serotonin reuptake inhibitors. Conclusions: The overall prescription rate of antidepressants was much lower than the estimated rates reported in other countries. TCAs were the primarily prescribed antidepressant. It is now expected that TCAs will be replaced by newer antidepressants.