휴대용 폐기능 검사기의 재현성과 기대치에 관한 연구

최준용,정희재,이건영,정승연,황준호,이형구,정승기,Choi, Jun-Yong,Jung, Hee-Jae,Lee, Kun-Young,Jeong, Seung-Yeon,Hwang, Joon-Ho,Rhee, Hyung-Koo,Jung, Sung-Ki 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3

Objectives : The object of this study was to evaluate repeatability of portable spirometry and to determine an appropriate equation for predicted value. Materials and Methods : The subjects were 76 men and 45 women recruited from among Kyunghee University oriental medical students. Portable spirometry was performed via the procedure recommended in ATS guidelines. Repeatability of spirometry was checked against ATS repeatability standards and NHLEP QC grade. Percentage of predicted value of non-smokers was calculated through a Caucasian population-based regression equation(by Morris et al.) and Korean population based regression equation(by Kim et al.). These were compared. Result : 91.7% of subjects matched repeatability standards of ATS and 95% of subjects got interpretable NHLEP QC grades of A, B, and C. Mean percentage of predicted value by Morris et al. were as follows: Mean of FVC% was 90.86, FEV1% was 96.66, FEV1/FVC% was 107.48. Mean percentage of predicted value by Kim et al. were as follows. Mean FVC% was 92.38, FEV1% was 89.77, FEV1/FVC% was 96.95. Conclusions : Results of this study show that more than 90% of subjects meet repeatability criteria. This supports a role for the portable spirometer as a primary oriental medical office tool. Further, results are a verify that they Korean population-based predicted value equation is a more appropriate standard than the Caucasian population-based one, but a still more accurate standard is needed for the Korean adult population.

두시하태독법의 Th2 분화 조절을 통한 알레르기 비염 완화 효과

최준용,안상현,김기봉,Choi, Jun-yong,Ahn, Sang-hyun,Kim, Ki-bong 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This study investigated the effects of Douchi Hataedock on Th2-skewed conditions to control allergic rhinitis. Methods: NC/Nga mice were divided into three groups: 10 mice were assigned to the control group (CTRL; no treatment), 10 mice to allergic rhinitis-induced (ARE) without treatment group, and 10 mice to the allergic rhinitis-induced (FGT) after Douchi Hataedock treatment group. The 3-week-old mice of the FGT group were given one 10 mg/kg dose of Douchi Hataedock extract and resensitized to allergic antigens at weeks four, five, and six. Allergic rhinitis was induced primarily in mice nasal cavities for five days after one week of final sensitization. The second induction used the same method one week after the first induction was completed. After one week, the nasal mucosal tissues of each group were observed. Immunohistochemical staining for IL-4, STAT6, CD40, $Fc{\varepsilon}RI$, substance P, MMP-9, $NF-{\kappa}B$ p65, p-IkB, and iNOS in the nasal mucosa was also performed. Results: The FGT group had less respiratory epithelial damage and less mucin secretion in goblet cells than the ARE group and showed a 62% decrease in IL-4, 85% decrease in STAT6, 71% decrease in CD40, 69% decrease in $Fc{\varepsilon}RI$, 43% decrease in substance P, 49% decrease in MMP-9, 43% decrease in NF-kB p65, 38% decrease in p-IkB, and 73% decrease in iNOS compared to the ARE group. Conclusions: Douchi Hataedock lessens inflammation in epithelial and goblet cells and reduces inflammatory mediator secretion in a mouse allergic rhinitis model.

청상보하탕(淸上補下湯)의 기관지천식환자에 대한 스테로이드 절약효과

최준용,이재성,주창엽,정희재,이형구,정승기,황우석,Choi Jun-Yong,Lee Jae-Sung,Ju Chang-Yeop,Jung Hee-Jae,Rhee Hyung-Koo,Jung Sung-Ki,Hwang Woo-Suck 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.1

Background : In recent years, the glucocorticoid hormone has become a fundamental medication for asthma. However, a long period of hormone administration will result. in general. side effects on many body parts as well as hormone dependence, which has become a serious problem for western physicians. Objectives : We aimed to identify the clinical effects of Cheongsanghoha-tang and the steroid sparing effects of Cheongsanghoha-tang on. Materials and Methods : A subject group consists of 36 asthmatics who had been treated with Cheongsanghoha-tang for four weeks. Cheongsanghoha-tang is a herbal decoction, which has been used of the traditional therapeutic agent of asthma. PFT, QLQAKA, blood eosinophil, serum IgE, Serum IL-4. IL-5, IFN-${\gamma}$ were checked before and 4weeks after the treatment. Results : The only FVC% in ICSG among asthmatic patients was increased significantly compared to NICSG. Treatment of Cheongsanghoha-tang for four weeks resulted in significant increase in QLQAKA. The NICSG treated with Cheongsangboha-tang for four weeks were no significant difference in the blood eosinophil, serum IgE, IL-4 and IL-5. The PFT and QLQAKA in NICSG were increased significantly after 4 weeks treatment. But the serum IFN-${\gamma}$ in NICSG was decreased significantly after 4 weeks treatment. Discontinuation of treatment with inhaled corticosteroid in ICSG resulted in insignificant changes in PFT, the blood eosinophil, the serum IgE, IL-4, IL-5 and IFN-${\gamma}$ and significant increase in QLQAKA. As a result. 8 of 13 cases were cured with hormones completely and the rest of ICSG reduced the dose of ICS. Conclusions : This study shows that Cheongsanghoha-tang has the effects on the improvement of pulmonary function and cures asthmatic patients. These findings demonstrate that Cheongsanghoha-tang has the steroid sparing effect. Some satisfactory therapeutic results have been obtained in treating hormone-dependent asthma by Cheongsanghoha-tang. However. the concept and mechanism of hormone-dependent asthma have not been fully defined yet, and the standard for judging therapeutic effects have not been established. Obviously further researches concerning all these are still necessary.

HIV 감염인에서 흔히 보는 감염

최준용 ( Jun Yong Choi ) 대한내과학회 2013 대한내과학회지 Vol.84 No.2

Opportunistic infections (OIs) are defined as infections that are more frequent or more severe because of immunosuppression in HIV-infected persons. Before the widespread use of combination antiretroviral therapy (ART), OIs were the major cause of morbidity and mortality of HIV-infected persons. Although hospitalizations and deaths have decreased since the implementation of ART, OIs remain a leading cause of morbidity and mortality in HIV-infected persons. The frequent OIs in HIV-infected persons are tuberculosis, Pneumocystis pneumonia, candidiasis, Cytomegalovirus infection, toxoplasmosis, cryptococcosis, and so on. The aim of the present review is to provide a brief introduction on clinical features, diagnosis and treatment of common OIs in HIV-infected persons. (Korean J Med 2013;84:179-185)

Black subway

최준용 ( Choi Jun Yong ) 한국기초조형학회 2018 한국기초조형학회 작품집 Vol.2018 No.2

다 개체 로봇의 협업기법에 관한 연구

최준용(Jun-Yong Choi),김동환(Dong Hwan Kim),이귀형(Gui Hyung Lee) 대한기계학회 2010 大韓機械學會論文集A Vol.34 No.8

이 연구에서는 다 개체 로봇에 의해 하나의 로봇을 자율적으로 포획하는 협업제어에 관한 연구를 제안한다. 제안된 방안은 각 로봇에 대한 작업역할을 지정하는 역할 분류기, 단일 로봇의 행동 선택기 그리고 복잡한 상황을 대처하는 협업관리기로 구성되어 있다. 이 연구에서는 주변의 다개체 로봇의 다양한 행동을 통하여 단위 로봇을 특정지역으로 몰아가는 결과를 시뮬레이션을 통하여 그 적절성을 검증하였다. In this study, we proposed duty executions to confine a robot in a specific place with multiple robots. The proposed method involved the use of a role classifier for assigning labor roles, behavior selector for each robot, and a collaboration manager for handling complex situations. Further, we verified the validity of the proposed method by performing simulations to confine a robot in the specific location by using multiple robots.

HIV 감염 예방의 최신 지견

최준용 ( Jun Yong Choi ) 대한내과학회 2016 대한내과학회지 Vol.90 No.6

There are many evidence-based methods to prevent human immunodeficiency virus (HIV) transmission. This review describes recent updates on the prevention of HIV infection via sexual contact, mother-to-child transmission, and occupational exposure. The use of antiretroviral therapy to prevent HIV has been a major accomplishment. Successful strategies for preventing the sexual transmission of HIV include the implementation of treatment for prevention, pre-exposure prophylaxis, and microbicides. Mother-to-child HIV transmission can be minimized by screening and administering pre-, intra-, and postpartum prophylaxis. Adherence to universal precautions and post-exposure prophylaxis are effective preventive measures for occupational exposure. The implementation of prevention strategies based on scientific evidence should decrease the spread of this epidemic. (Korean J Med 2016;90:474-480)

폼에 기반한 HTML 문서 생성 방법

최준용(Choi Jun Yong),김병기(Kim Byung Ki) 한국정보처리학회 1999 정보처리학회논문지 Vol.6 No.2

An information structure of large size hypermedia application is usually hierarchical, and the sibling nodes in this structure have same or similar tags and contents. A word "form" that means the common set of sibling nodes in the hierarchical information structure is used in this paper. It proposes a design method that divides form and content from nodes and I proposes HTML page generation algorithm from forms and contents. This method has reusability of form, maintainability of documents and reduction of cost for authoring.

토양 소수성에 따른 미량원소의 흡착 및 이동

최준용(Jun-Yong Choi),이상수(Sang Soo Lee),옥용식(Yong Sik Ok),천소을(Soul Chun),주영규(Young Kyoo Joo) 한국토양비료학회 2012 한국토양비료학회지 Vol.45 No.2

소수성 토양이란 물방울이 떨어져도 자연스럽게 젖지 못하고 표면 위에 그대로 존재하는 토양을 말한다. 소수성 토양은 토양입자들 사이 혹은 토양입자와 그 중간물질의 사이에 소수성 유기물질이 침투하여 입자를 코팅하여 소수성을 띠게 되는 것이다. 토양이 소수성화가 되면 심한 침식과 침출, 농약의 급속한 침출, 식물이 이용할 수 있는 많은 양의 물과 영양분의 손실 그리고 농작물과 목초의 생산성 감소 등을 야기한다. 본 실험에서는 미량원소가 어떤 흡착과 이동 메커니즘을 갖는지를 배치 실험과 컬럼 실험을 통해 비교 평가하였다. 배치 실험에서는 Cu<SUP>2+</SUP>, Mn<SUP>2+</SUP>, Fe<SUP>2+</SUP>, Zn<SUP>2+</SUP> 및 Mo<SUP>5+</SUP>를 이용하여 일반 토양과 소수성 토양의 수착의 차이, 소수성 정도에 따른 차이, 각각의 미량원소 별 차이를 비교하였고, 컬럼 실험에서는 피흡착물질인 미량원소 Fe<SUP>2+</SUP> 및 Mo<SUP>5+</SUP>에 대한 탈착성능 비교와, 특정시간에 따른 공간적 농도 분포를 측정하였다. Fe<SUP>2+</SUP>와 Mo5+의 경우 비소수성 토양보다 소수성 토양에서 더 높은 흡착을 나타났다. Fe<SUP>2+</SUP>의 흡착성능은 소수성 토양별 40% 〉 15% 〉 0% 순으로 나타났다. 특히 Mo5+의 경우 0%, 15% 및 40%의 소수성 토양에서 초기에는 비슷한 경향을 보였으나 시간이 지나면서 소수성 토양에서 비소수성 토양보다 빠른 탈착속도를 보였다. Fe<SUP>2+</SUP>와 Mo5+의 파과곡선 분석결과 소수성 토양에서 더 빠른 이동속도를 나타내었다. Water repellency which affects infiltration, evaporation, erosion and other water transfer mechanisms through soil has been observed under several natural conditions. Water repellency is thought to be caused by hydrophobic organic compounds, which are present as coatings on soil particles or as an interstitial matter between soil particles. This study was conducted to evaluate the characteristics of the water repellent soil and transport characteristics of trace elements within this soil. Capillary height of the water repellent soil was measured. Batch and column studies were accompanied to identify sorption and transport mechanism of trace elements such as Cu<SUP>2+</SUP>, Mn<SUP>2+</SUP>, Fe<SUP>2+</SUP>, Zn<SUP>2+</SUP> and Mo<SUP>5+</SUP>. Difference of sorption capacity between common and repellent soils was observed depended on the degree of repellency. In the column study, the desorption of trace elements and the spatial concentration distribution as a function of time were evaluated. The capillary height was in the repellency order of 0% 〉 15% 〉 40% 〉 70% 〉 100%. No water was absorbed in soil indicating 〉70% repellency. Using trace elements, Fe<SUP>2+</SUP> and Mo<SUP>5+</SUP> showed higher sorption capacity in the repellent soil than in non-repellent soil. The sorption performance of Fe<SUP>2+</SUP> was found to be in the repellency order of 40% 〉 15% 〉 0%. Our results found that transfer of Mo5+ had similar sorption tendency in soils having 0%, 15% and 40% repellency at the beginning, however, the higher desorption capacity was observed as time passes in the repellent soil compared to in non-repellent soils.

소수성 토양에서의 미량원소의 이동

최준용(Jun-Yong Choi),천소을(Soul Chun),주영규(Young-Kyoo Joo) 한국토양비료학회 2007 한국토양비료학회 학술발표회 초록집 Vol.2007 No.10