치매환자와 주 부양자의 관계에 따른 돌봄 부담 요인

최정은(Choi, Jung-Eun),이연화(Lee, Yeon-Hwa) 고령자치매작업치료학회 2021 고령자.치매작업치료학회지 Vol.15 No.2

목적 : 본 연구의 목적은 치매안심센터를 이용하는 주 부양자의 특성별 맞춤형 프로그램과 지원방안을 제시하고자 하며, 치매정책 사업지침 내 가족지원사업의 기초자료를 마련하고자 한다. 연구방법 : 보건소 치매안심센터에 등록된 치매환자의 주 부양자를 대상으로 하였다. 대상자의 일반적 특성 및 우울의 정도와 치매태도, 부양부담, 치매환자의 정신행동증상 여부를 포함한 자가기입 돌봄부담 분석을 활용하여 측정하였다. 측정도구는 각각 Patient Health Questionnaire-9: PHQ-9와 Dementia Attitude Scale: DAS, Short Zarit Burden Inventory: S-ZBI로 평가하였고, 치매환자의 정신행동증상 여부는 Neuropsychiatric Inventory Questionnaire: NPI-Q를 통해 치매환자의 심한정도 및 보호자의 고통정도를 알아보고자 하였다. 또한, 치매안심센터 내 가족지원사업의 서비스 요구도를 5가지 명목척도로 조사 하였다. 연구조사 방법은 우편 및 대면 설문을 통해 진행하였다. 연구 목적에 대한 설명 및 동의를 포함한 설문지를 총 423부를 배부하여 이 중 152부를 회수하였고, 응답에 충실하지 못한 41부를 제외하여 최종 111부룰 대상으로 비교⋅분석하였다. 연구결과 : 치매환자와 주 부양자의 관계에 따른 돌봄부담을 비교한 결과 환자의 정신행동증상여부 (p<.05)에서 배우자 외 집단에서 유의하게 높은 차이를 보였다. 또한, 치매환자의 특성과 부양자의 돌봄 부담에 관한 영향요인을 파악하고자 환자와의 관계를 중심으로 조절 효과를 확인한 결과, 환자의 연령과 부양자 간의 관계가 치매태도에 있어서 상호작용하는 것으로 나타났다. 결론 : 치매안심센터 내 가족지원사업 운영 추진 시 주 부양자의 인구학적 특성 및 환자와의 관계에 따른 맞춤형 프로그램이 요구된다. Objective : The purpose of this study is to collect basic data necessary to propose customized programs and support plans for each characteristic of the Caregiver s who use the Center for dementia. Methods : The subjects were the Caregiver of dementia patients registered at the Center for dementia at the public health center. The general characteristics and depression of the subjects were evaluated as Patient Health Questionnaire-9: PHQ-9, Dementia Attitude Scale: DAS, and the Caregiver’s support burden was evaluated as Short Zarit Burden Inventory: S-ZBI, and whether Behavioral and psychological Symptoms of Dementia Scale (Neuropsychiatric Inventory Questionnaire, NPI-Q) to determine the severity of dementia patients and the degree of pain of caregiver. In addition, a survey was conducted on the service needs of the family support project of the Center for Dementia, The survey was conducted through mail and face-to-face interviews. A total of 423 copies were distributed and 152 of them were recovered, and the final 111 copies were compared and analyzed, excluding 41 copies that were not faithful to the survey. Results : As a result of comparing the burden of care according to the relationship between dementia patients and their caregiver, it was analyzed that there was a significant difference in Behavioral and psychological Symptoms of Dementia (p<.05). In addition, as a result of identifying the characteristics of dementia patients and the factors influencing the care burden of dependents and confirming the moderating effect centering on the relationship with the patient, it was analyzed that there is an interaction according to the patient s age. Conclusion : The Center for dementia needs to organize a program suitable for the characteristics of the caregiver of dementia patients, and for this purpose, the relationship with the patient should be considered.

제왕절개 환자에서 적극적 가온 요법의 효과

최정은(Choi, Jung Eun),김미선(Kim, Mee Sun),송진란(Song, Jin Ran) 기본간호학회 2017 기본간호학회지 Vol.24 No.3

Purpose: The aim of this study was to synthesize the best available evidence for active warming interventions during cesarean section. Methods: A database search was done for randomized controlled trials utilizing active warming interventions. Maternal temperature, shivering and neonatal temperature were evaluated as outcome variables. Data were analyzed using Cochrane Review Manager software Version 5.3. Results: Thirteen studies including 1306 patients were reviewed. The degree of lowering of maternal temperature decreased in the warmed fluids (MD 0.51; p=.004) and warming mattress interventions (MD 0.22; p<.001) compared with control groups. Incidence of shivering was also lower in the active warming group (OR 0.55; p=.003). There was no statistically significant difference in maternal temperature with a forced air warming intervention (MD 0.64; p=.15) or in neonatal temperature (MD 0.12; p=.26). Conclusion: Findings show that with warmed fluids and warming mattresses applied during cesarean sections maternal temperature decline was reduced and also the incidence of shivering declined, but no significant effect was observed for forced air warming interventions. These findings provide a basis for developing a warming guideline for women having a cesarean section and will help to improve the quality of care for cesarean section patients.

성인 천식 환자에서 체질량지수와 기도과민성 및 폐기능의 연관성

최정은 ( Jung Eun Choi ),신태림 ( Tae Rim Shin ),박상면 ( Sang Myeon Park ),김주희 ( Joo Hee Kim ),신성호 ( Sung Ho Shin ),이현영 ( Hyun Young Lee ),장주아 ( Juah Jang ),이훈구 ( Hun Gu Lee ),김철홍 ( Cheol Hong Kim ),현인규 ( In 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1

Purpose: Obesity is commonly regarded as a risk factor for asthma development, poor asthma control, and poor response to asthma therapy. However, its relationships are not always consistent. Gender difference has been reported to influence asthma severity and asthma control. We investigated the contribution of obesity to airway hyperresponsiveness (AHR) and lung function before and after treatment in adult asthmatics. Methods: The medical records of a total of 323 adult asthmatics were analyzed retrospectively. Asthma was diagnosed based on the positive result of methacholine bronchial provocation test (PC20≤25 mg/mL) or bronchodilator test (≥12% and 200-mL improvement in forced expiratory volume in 1 second after inhalation of a bronchodilator). Follow-up spirometry was performed in 113 patients after at least 3 months of asthma treatment with controller medication. Percent change between spirometry before and after treatment was defined as {[(value after treatment.value before treatment)/value before treatment]×100}. Body mass index (BMI, weight [kg]/height [m2]) was categorized into underweight (<18.5), normal weight (18.5.24.9), overweight (25.0.29.9), and obese (>30) according to the world health organization classification. Results: BMI did not show any significant correlation with PC20 value of methacholine provocation test and each lung function parameter before and after treatment. When we divided the study subjects according to gender and age, BMI was negatively correlated with PC20 value only in female adult asthmatics under 65 years old (r=.0.024, P=0.036). Conclusion: Obesity is positively correlated with the intensity of AHR in female adult asthmatics. Gender seems to differentially contribute to the relationship between BMI and AHR. (Allergy Asthma Respir Dis 2014;2:16-22)

식품 및 환경 기타 국내에서 유통 중인 축산환경개선제의 표기사항 및 항생제 내성 현황조사

최정은 ( Jung Eun Choi ),이은영 ( Eun Young Lee ) 한국미생물생명공학회 2009 한국미생물·생명공학회지 Vol.37 No.3

불멸화된 일차 간세포를 이용한 C형 간염바이러스의 in vitro 배양

최정은 ( Jung Eun Choi ),허원희 ( Won Hee Hur ),신주엽 ( Ju Yeop Shin ),박련숙 ( Lian Shu Piao ),윤승규 ( Seung Kew Yoon ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.3

Background/Aims: It is essential to develop an in vitro culture model of primary hepatocytes for the study of hepatocellular function and the pathogenesis of hepatitis C virus (HCV) infection. In this study, we have established the immortalized primary human hepatocyte (IPHH) and performed in vitro culture of HCV derived from human patient. Methods: Primary human hepatocytes were isolated from surgically resected liver tissue and then were immortalized by transfection with the SV40 large T antigen. The characterization of the IPHH during culture was analyzed by immunocytochemistry, RT-PCR, Western blot, ELISA, and soft agar assay. Next, sera and/or liver tissue homogenates from surgically resected liver tissues of patients with HCV infection were inoculated for the culture of HCV in IPHH. After HCV RNA extraction from IPHH and culture media, positive or negative stranded HCV RNA was examined by specific nest RT-PCR. Results: IPHH expressed liver-associated proteins but did not express alpha-fetoprotein. Also IPHH showed ammonia removal activity. With regard to its malignant potential, colony formation in soft agar assay was not observed. Next, positive and negative stranded HCV RNAs in IPHH infected with patient`s sera plus liver tissue homogenates were clearly detected whereas those in IPHH infected with only patient`s sera were not detected. Conclusions: These results demonstrated the phenotypic characteristics of IPHH and the feasibility in vitro culture system of HCV infected human samples. This system might be useful for study of pathogenesis of HCV infection or hepatocyte-based applications. (Korean J Gastroenterol 2008;52:150-160)

역사물『요시쓰네(義經)』의 장르별 표현양상의 비교고찰 : 오슈 도피(奥州落ち) 일화를 중심으로

최정은(崔廷銀)(Choi, Jung-Eun),최중락(崔中洛)(Choi, Joong-Rak) 일본어문학회 2012 일본어문학 Vol.56 No.-

전통 한옥의 지붕 형태와 기둥 재료 변화에 따른 한 스타일 미적 정도 측정에 관한 연구

최정은(Choi, Jung-Eun),이현수(Lee, Hyun-Soo) 대한건축학회 2011 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.31 No.1(계획계)

부 · 모의 양육행동과 유아의 외현화 문제행동의 관계에서 정서조절능력의 매개효과

최정은(Jung Eun Choi),이소연(SoYean Lee) 한국아동학회 2017 아동학회지 Vol.38 No.1

Objective: The purpose of this study was to investigate the mediating effects of emotional regulation abilities on the relationship between parenting behavior and preschoolers’ externalizing behavior problems. Methods: A survey was conducted with the parents of 166 preschoolers; the children were attending seven different daycare centers in Seoul. Results: The results were as follows: First, emotional regulation abilities fully mediated the relationship between fathers’ rejection-restriction parenting behavior and externalizing behavior problems. Second, emotional regulation abilities fully mediated the relationship between mothers’ warmth-acceptance, rejection-restriction, and permissive-neglectful parenting behavior and externalizing behavior problems. Third, after controlling for fathers’ parenting behavior, emotional regulation abilities fully mediated the relationship between mothers’ parenting behavior and externalizing behavior problems. Conclusion: Both parenting behavior and emotional regulation abilities should be considered when attempting to understand the development of preschoolers’ externalizing behavior problems. In particular, the results from this study stress the important role of emotional regulation abilities in decreasing externalizing behavior problems and buffering against the influence of negative parenting behavior.

사상자탕과 가미사상자탕의 항염증 및 항산화 효과 비교 연구

최정은 ( Jung Eun Choi ),박보경 ( Bo Kyung Park ),진미림 ( Mi Rim Jin ) 대전대학교 한의학연구소 2015 혜화의학회지 Vol.23 No.2

Objectives : The anti-inflammatory and antioxidant effects of water extracts of Sasangja-tang(SSJ) and Gami-sasangja-tang(GSJ) were investigated. The effects of SSJ and GSJ were compared. Methods : We performed cell viability assay in HaCaT cells and RAW 264.7 cells using 3- (4,5-dimethylthiazol-2-yl)-2, 5 diphenyltetrazolium bromide(MTT) assay. We measured chemokines( regulated on activation normal T-cell expression and secreted ; RANTES/CCL5, interferon-inducible protein; IP-10/CXCL10, macrophage-derived chemokine; MDC/CCL22) in HaCat cells, also we measured cytokines (tumor necrosis factor-α; TNF-α, interleukin-6; IL-6) and nitric oxide(NO) production in RAW 264.7 cells using enzyme-linked immunosorbent assay(ELISA) and NO assay. Western blot assay was used to evaluate the expression for inducible nitric oxide synthase(iNOS) in RAW 264.7 cells. Results : SSJ and GSJ did not affect the cell viability at the concentrations treated (0-800 μg/ml). As a result of SSJ and GSJ treatment in HaCat cells stimulated by TNF-α(10 ng/ml) and interferon(IFN)-γ(10 ng/ml), the production of RANTES and IP-10 was inhibited significantly. However there was no significant difference in the secretion of MDC. And in RAW 264. 7 cells stimulated by lipopolysaccharide(LPS, 1 μg/ml), SSJ and GSJ treatment significantly inhibited the secretion of TNF-α and IL-6 and the production of NO. The expression of iNOS was also decresed by SSJ and GSJ treatment in RAW 264. 7 cells. Compared with SSJ, GSJ was superior to SSJ in inhibition of RANTES, IP-10, TNF-α, IL-6 and NO production at the concentration of 200 μg/ml. Conclusion : Both SSJ and GSJ have anti-inflammatory and antioxidant effects. And GSJ has better effects than SSJ.

NHK드라마「요시쓰네(義經)」에 나타난 영웅 서사구조의 원형과 변용

최정은(Jung-Eun Choi) 한국콘텐츠학회 2012 한국콘텐츠학회논문지 Vol.12 No.2

영웅은 TV드라마의 오랜 소재이다. TV드라마 속에서의 역사적 영웅은 대중의 욕망에 대한 대리자이자 그것의 집약체로서 기능하는데, 특정 시기 드라마가 형상화 해내는 영웅의 모습과 그것을 환영하는 시청자간의 소통은 당대 대중의식을 가름할 수 있는 장치가 되기도 한다. 본 연구는 오늘날 각종 문화 영역에서 환영받고 있는 일본의 역사적 영웅 ‘요시쓰네’를 주인공으로 한 드라마를 영웅의 서사연구, 스토리 분석에 있어서 중요한 위치를 차지하고 있는 조셉 캠벨의 17가지 영웅 서사 단계를 토대로 분석하여 원형과 변용을 알아보았다. 드라마는 캠벨의 17단계 중 11가지 단계를 적용하고, 2가지단계의 생략과 4가지단계의 변형을 보여주며, 대중문화 콘텐츠로 재탄생하기 위해서는 일정한 선택과 변형이 필요하다는 것을 알 수 있었다. The hero is in the TV dramas long. TV drama Heroes historical blip on the public’s desire to delegate to the body and its functions as an intensive, which have a specific period drama that soars like a heros welcome and it is the communication between the viewer a sense of contemporary popular devices that can be separated. This study today, the various cultural areas which are becoming popular in Japan’s historical hero ‘Yoshitune’ a heroic drama, the hero’s narrative research stories In the analysis occupies an important place in the Joseph Campbell’s 17 steps of heroic narrative, based on analysis achetype and adaptation. Campbell, 11 of the 17 stage dramas to apply different levels, and the omission of two steps, and shows a variation of the four stages, in order to relaunch the popular culture as the content selection and a constant strain was able to find out that you need.