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최정민(Jeongmin Choi),김광우(Kwangwoo Kim) 한국태양에너지학회 1996 한국태양에너지학회 논문집 Vol.16 No.3
建物에서의 日照權 確保는 심리적, 시각적 효과와 더불어 쾌적하고 위생적인 環境維持를 위해서 필요불가결하다. 이를 위해 각국에서는 關聯法에 隣棟距離規定(Distance Criteria)과 性能規定(Performance Criteria)을 두어 적용하고 있다. 그러나 우리나라의 경우 상기 規定들 가운데 設計要素에 직접적으로 제한을 가하는 隣棟距離規定을 주로 적용하고 있으며, 일정수준의 日照環境을 충족시키도록 요구하는 性能規定은 關聯制度 및 이를 검증할 수 있는 評價方法이 일반화되지 못한 관계로 거의 적용되지 않고 있는 실정이다.<br/> 이에 本 硏究에서는 일정수준의 日照環境 確保를 目標로 국내외의 關聯法規上의 내용 및 문제점들을 살펴 보았으며, 性能規定 適用時 이를 정량적으로 評價할 수 있는 方法 및 技法들을 검토하여 제시하였다. The study aims to make it possible to evaluate solar expose rights by the performance criteria in building code. To make the minimum sunshine hours can be achieved in building, the building code was reviewed and evaluation tools were examined.<br/> By applying the performance criteria with evaluation tools it is possible to design the buidings more freely and to evaluate sunshine hours more quantitatively than the distance criteria.
Cosolvent System에서 이온성 유기화합물의 생분해 및 흡착 특성
최정민 ( Jeongmin Choi ),윤홍진 ( Hongjin Yun ),오동기 ( Dongki Oh ) 한국환경농학회 2023 한국환경농학회 학술대회집 Vol.2023 No.0
The existing cosolvency-induced sorption model, which is used to predict the fate of organic solutes in a cosolvent system, is not capable of completely explaining the effects of various interactions between solutes, solvents, and sorbents. Hence, this study aims to evaluate the effect of functional groups and aromatic rings on sorption onto activated carbon in a methanol-water system. The experiment was conducted on a hybrid bioreactor, which consists of a Sorption module and a biodegradation module, was investigated for the enhanced treatment of a organic acid mixture. Benzoic acid, 1-naphthoic acid, and 9-anthroic acid were chosen as organic sorbates, and activated carbon was used as the sorbent. We also summarized information on the biodegradation of each kind of organic acids under cosolvent system. As the microbial population increases, it shows high organic acids removal efficiency. The equilibrium concentrations were analyzed via GC-FID. As explained by the existing cosolvency model, for organic acids at pH 3 (i.e., pK<sub>a</sub>>pH) and pH 7 (i.e., pK<sub>a</sub><pH), the sorption (K<sub>m</sub>) of organic acids decreased on adding methanol. On the other hand, this study showed unexpected results that do not consistent with the existing cosolvency model. At pH 7 for the CaCl<sub>2</sub> system, K<sub>m</sub> increases with increasing methanol volume fractions. A decrease in the dielectric constant of the liquid phase, caused by the presence of methanol, might result in an increase in K<sub>m</sub>. Regardless of the cosolvency power (σ), as the number of aromatic rings in the solute increases, K<sub>m</sub> is reduced in the order of benzoic acid > 1-naphthoic acid > 9-anthroic acid. In order to accurately predict the fate of acidic solutes in a variety of environment, studies for quantitatively estimating of effects of various interaction on the sorption should be conducted. Through the studies the current cosolvency induced sorption model can be advanced.
헬리코박터 파일로리 제균 치료가 위암 관련 유전자의 CpG Island 과염기화에 미치는 영향
최정민 ( Jeongmin Choi ),김상균 ( Sang Gyun Kim ),김병관 ( Byeong Gwan Kim ),고성준 ( Seong-joon Koh ),김지원 ( Ji Won Kim ),이국래 ( Kook Lae Lee ) 대한소화기학회 2016 대한소화기학회지 Vol.68 No.5
Background/Aims: Helicobacter pylori infection induces aberrant DNA methylation in gastric mucosa. We evaluated the long-term effect of H. pylori eradication on promotor CpG island hypermethylation in gastric carcinogenesis. Methods: H. pylori-positive patients with gastric adenoma or early gastric cancer who underwent endoscopic resection were enrolled. According to H. pylori eradication after endoscopic resection, the participants were randomly assigned to H. pylori eradication or non-eradication group. H. pylori-negative gastric mucosa from normal participants provided the normal control. CpG island hypermethylation of tumor-related genes (p16, CDH1, and RUNX-3) was evaluated by quantitative MethyLight assay in non-tumorous gastric mucosa. The gene methylation rate and median values of hypermethylation were compared after one year by H. pylori status. Results: In H. pylori-positive patients, hypermethylation of p16 was found in 80.6%, of CDH1 in 80.6%, and of RUNX-3 in 48.4%. This is significantly higher than normal control (p16, 10%; CDH1, 44%; RUNX-3, 16%) (p<0.05). In the H. pylori eradication group, methylation rates of p16 and CDH1 decreased in 58.1% and 61.3% of the patients, and the median values of hypermethylation were significantly lower at one year compared with the non-eradication group. However, RUNX-3 hypermethylation did not differ significantly at one year after H. pylori eradication. The non-eradication group hypermethylation did not change after one year. Conclusions: H. pylori infection was associated with promotor hypermethylation of genes in gastric carcinogenesis, and H. pylori eradication might reverse p16 and CDH1 hypermethylation. (Korean J Gastroenterol 2016;68:253-259)