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A Case of Nasal Chondromesenchymal Hamartoma Misunderstood as a Sphenochoanal Polyp in an Adult
최장원,김상민,김지연,김용완 대한이비인후과학회 부산,울산,경남 지부회 2017 임상이비인후과 Vol.28 No.2
Nasal chondromesenchymal hamartoma (NCMH) is a rare example of hamartoma and mainly involves the nose and paranasal sinuses. We report a case of NCMH in a 24-year-old Asian adult, which was misunderstood as a sphenochoanal polyp. Endoscopic examination showed the nasal passages were obstructed with a polypoid mass originated from left posterior ethmoid and sphenoidal sinus. Computed tomography (CT) demonstrated non-enhancing bulging soft masses. The patient underwent left endoscopic sinus surgery and resection of left sphenochoanal polypoid mass. Histopathology showed an inflammatory polyp with chondroid metaplasia. After 18 months, the patient visited the hospital again with a recurred polypoid mass at the same area. Revision endoscopic sinus surgery was performed. Finally, based on the histologic findings and results of immunohistochemistry, the nasal polyp was diagnosed as chondromesenchymal hamartoma. In the case of chondroid proliferations of the nose and paranasal sinuses, NCMH should be considered a differential diagnosis.
융합의 시대에(사물인터넷시대에) 남북한 사회통합을 위한 북한이탈주민 보호 및 정착지원법 개선방안 -북한이탈주민의 경제적 적응 및 심리·사회적 적응을 중심으로-
최장원 한국사물인터넷학회 2020 한국사물인터넷학회 논문지 Vol.6 No.2
본 연구의 목적은 남한으로 이주한 북한이탈주민의 경제적 적응과 심리·사회적 적응 실태를 중심으로 북한이탈주민의 보호 및 정책지원법의 문제를 분석하고 개선법을 제안하고자 한다. 이를 위해 서울 및 경기도 지역에 소재한북한이탈주민 225명을 대상으로 설문을 실시하였으며, SPSS 22.0 프로그램을 사용하여 분석을 실시하였다. 주요 연구결과는 다음과 같다. 첫째, 북한이탈주민들의 경제적 적응은 대체적으로 낮은 수준이었다. 둘째, 북한이탈주민들의 심리‧ 사회적 적응 상태는 전반적으로 낮은 가운데 문화적응스트레스와 친구관계, 신체 및 정신 건강에 대한 만족도가 특히낮은 수준이었다. 셋째, 북한이탈주민의 심리문화적 적응전략과 사회적 지지는 삶의 만족도에 유의한 긍정적 영향을미쳤으며, 적응스트레스는 삶의 만족도에 유의한 부정적 영향을 미쳤다. 이러한 연구결과를 바탕으로 북한이탈주민의경제적 적응과 심리적 적응을 증진시킬 수 있는 실질적인 정책적 대안을 제시하였다. This study examines the North Korean defectors' economic and psychological adjustment status in South Korean society focusing on the specificity of North Korean defectors with the social integration perspective. We conducted a questionnaire survey of 225 North Korean defectors in Seoul and Gyeonggi-do and conducted analysis using the SPSS 22.0 program. The results of the study are as follows. First, the economic adaptation of North Korean defectors was evaluated to be generally low. Second, North Korean refugees' psychological and social adjustment status is generally lower than average, especially cultural adaptation stress, friendship, and satisfaction with physical and mental health. Third, the psychological and cultural adaptation strategy and social support of defectors affected the life satisfaction positively and the adaptation stress had significant negative impact on life satisfaction. Therefore, strategies which reducing adaptive stress and enhancing psychological and cultural adaptation strategies are needed to be implemented in South Korean society. Based on results, policy alternatives were discussed.
사회복지생활시설 종사자의 대인관계 기술과 직무스트레스에 관한 융합 연구: TSL 프로그램 개입을 통한 의생명과학적 효과 검증
최장원 한국융합학회 2019 한국융합학회논문지 Vol.10 No.3
The purpose of this study is to examine the effect of TSJ-JSM (Job Stress Management) program, which was developed for improving interpersonal relationship and mitigating job stress among social workers through convergence methods with biomedical and social scientific measurements. In order to achieve the purpose, utilizing quasi-experimental design with non-equivalent control group design was applied. Participants were recruited among social welfare residential facility workers with volunteer intention, and 21 participants divided into three groups randomly: experimental, comparison, and control groups consisted of 7 workers respectively. TSL-JSM program consisted of 12 sessions were implemented to experimental group, on the other hands, other employee assistant program with 12 stages was applied to comparison group. Data analysis for verification of TSL-JSM program was conducted with SPSS 25.0. Both social scientific and biomedical scientific measures show that TSL-JSM program has most strong effects on enhancing interpersonal relationship skills and allaying level of job stress by levels of increased HRV SDNN and decreased Corisol. 본 연구의 목적은 사회복지생활시설종사자의 대인관계기술 향상과 직무스트레스 감소를 위해 개발된 프로그램인 TSL-JSM(Job Stress Management)의 효과를 사회과학과 의생명과학적 방법을 융합적으로 적용하여 검증하는 것이다. 프로그램 효과성 검증을 위해 유사실험 설계를 활용하여 비동일 통제집단 설계를 적용하였다. 연구대상은 경남소재 사회복지법인 산하 생활시설의 종사자 중 자발적 참여자로 구성된 실험집단 7명, 비교집단 7명, 통제집단에 7명이 배정되었으며, 실험집단에는 12회기로 이루어진 TSL-JSM 프로그램을 적용하였고, 비교집단에는 12회기의 시설 종사자들의 대인관계기술 강화프로그램을 적용하였다. 최종 자료 분석은 SPSS 25.0 프로그램을 이용하여 공분산분석, 윌콕슨 순위검증을 실시하였다. 연구결과, 타집단에 비해 실험집단에서 유의미한 대인관계 기술 향상 및 직무스트레스 감소를 보였으며 의생명과학지표인 심박변이도와 코티졸의 긍정변화가 검증되었다.
Water-Soluble Red Pigment Production by Paecilomyces sinclairii and Biological Characterization
최장원,박종필 한국생물공학회 2018 Biotechnology and Bioprocess Engineering Vol.23 No.2
Natural pigments have several advantages over synthetic colorants. In this study, the production of red pigment produced by Paecilomyces sinclairii in microbial fermentation was demonstrated and the pigment was purified and characterized. The red pigment was produced from submerged fungal fermentation and fractionated by medium pressure flash chromatography. After fractionation, the spectrophotometric characterization of the red pigment revealed an λmax at 520 nm. Antimicrobial activity of the red pigment fraction was also studied against Escherichia coli O157 and Pseudomonas aeruginosa PAO1. The fraction (F2-F6) of the red pigment exhibited broad-spectrum antimicrobial activity in both bacteria. These results demonstrate the potential of this pigment in inhibiting bacterial growth and in food processing and other foodrelated applications.